Ribokinase-like family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Alpha and beta proteins (a/b) [ 51349] (147)
• Fold: Ribokinase-like [ 53612] (3)
• Superfamily: Ribokinase-like [ 53613] (5)
• Family: Ribokinase-like [ 53614] (9)

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Family statistics

	Genomes (2,346)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	7,162	50,551	16
Proteins	7,159	50,547	16

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Fructokinase	0	2.44	--	DIRECT
Enzyme Commission (EC)	Adenosine kinase	0	2.741	--	DIRECT
Enzyme Commission (EC)	Tagatose-6-phosphate kinase	0	2.741	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0	--	DIRECT
Enzyme Commission (EC)	5-dehydro-2-deoxygluconokinase	0	2.741	--	DIRECT
Enzyme Commission (EC)	Transferring phosphorous-containing groups	0	0.2728	--	DIRECT
Enzyme Commission (EC)	Ribokinase	0.000000000000002579	2.741	--	DIRECT
Enzyme Commission (EC)	1-phosphofructokinase	0.0000000000008084	2.741	--	DIRECT
Enzyme Commission (EC)	Phosphotransferases with an alcohol group as accep	0	0.8381	Moderately Informative	DIRECT

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Worm Phenotype (WP)

Highlighted in gray are those with FDR_all>0.001

	WP term	FDR (all)	IC level	SDWP level	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	0.3438	--	DIRECT
Worm Phenotype (WP)	developmental timing variant	0	0.4548	--	DIRECT
Worm Phenotype (WP)	general pace of development variant	0	0.4786	--	DIRECT
Worm Phenotype (WP)	postembryonic development variant	0	0.269	--	DIRECT
Worm Phenotype (WP)	embryonic lethal	0	0.046	--	DIRECT
Worm Phenotype (WP)	lethal	0	0.00521	--	DIRECT
Worm Phenotype (WP)	fertility variant	0	0.05937	--	DIRECT
Worm Phenotype (WP)	retarded heterochronic variations	0	0.4548	--	DIRECT
Worm Phenotype (WP)	development variant	0	0.001482	--	DIRECT
Worm Phenotype (WP)	morphology variant	0	0.046	--	DIRECT
Worm Phenotype (WP)	organism development variant	0	0.00297	--	DIRECT
Worm Phenotype (WP)	organism morphology variant	0	0.1372	--	DIRECT
Worm Phenotype (WP)	organ system physiology variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	organism physiology variant	0	0.1342	--	DIRECT
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	0.1444	--	DIRECT
Worm Phenotype (WP)	reproductive system physiology variant	0	0.05515	--	DIRECT
Worm Phenotype (WP)	maternal sterile	0	0.1213	--	DIRECT
Worm Phenotype (WP)	hermaphrodite sterile	0	0.1203	--	DIRECT
Worm Phenotype (WP)	embryonic development variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	larval development variant	0	0.4322	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility variant	0	0.0947	--	DIRECT
Worm Phenotype (WP)	developmental growth variant	0	0.4991	--	DIRECT
Worm Phenotype (WP)	larval growth variant	0	0.4991	--	DIRECT
Worm Phenotype (WP)	sterile progeny	0	0.6547	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	0.1193	--	DIRECT
Worm Phenotype (WP)	fertility reduced	0	0.06449	--	DIRECT
Worm Phenotype (WP)	physiology variant	1	0	--	INHERITED FROM: hermaphrodite fertility variant || developmental growth variant || retarded heterochronic variations || larval lethal || reproductive system physiology variant || organism homeostasis metabolism variant || lethal || larval development variant || sterile progeny || organism physiology variant || progeny variant || slow growth || development variant || developmental timing variant || hermaphrodite sterile || growth variant || hermaphrodite fertility reduced || embryonic development variant || embryonic lethal || larval growth variant || general pace of development variant || fertility variant || postembryonic development variant || larval arrest || organ system physiology variant || maternal sterile || organism development variant || fertility reduced
Worm Phenotype (WP)	sterile	1	0.1135	--	INHERITED FROM: hermaphrodite sterile || maternal sterile || sterile progeny
Worm Phenotype (WP)	slow growth	0	0.4945	Least Informative	DIRECT
Worm Phenotype (WP)	larval lethal	0	0.5727	Least Informative	DIRECT
Worm Phenotype (WP)	larval arrest	0	0.4991	Least Informative	DIRECT
Worm Phenotype (WP)	progeny variant	0	0.6514	Least Informative	DIRECT

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Yeast Phenotype (YP)

Highlighted in gray are those with FDR_all>0.001

	YP term	FDR (all)	IC level	SDYP level	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	0.09186	--	DIRECT
Yeast Phenotype (YP)	stress resistance	0	0.1452	--	DIRECT
Yeast Phenotype (YP)	competitive fitness	0	0.1116	--	DIRECT
Yeast Phenotype (YP)	fitness	0	0.1096	--	DIRECT
Yeast Phenotype (YP)	resistance to chemicals	0	0.3202	Least Informative	DIRECT

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Arabidopsis Plant Ontology (AP)

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	shoot system	0	0.05272	--	DIRECT
Plant ANatomical entity (PAN)	collective plant structure	0	0.01555	--	DIRECT
Plant ANatomical entity (PAN)	flower bud	0.00001912	2.299	--	DIRECT
Plant ANatomical entity (PAN)	reproductive bud	0.00002248	2.299	--	DIRECT
Plant ANatomical entity (PAN)	reproductive shoot system	0.5956	0.3304	--	INHERITED FROM: reproductive bud || flower bud
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: collective plant structure || bud || reproductive bud || shoot system || flower bud
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.03998	--	INHERITED FROM: flower bud || bud || reproductive bud || shoot system
Plant ANatomical entity (PAN)	bud	0.00004258	2.202	Highly Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Transferring phosphorus-containing groups	0	0.7021	--	DIRECT
Enzyme Commission (EC)	Tagatose-6-phosphate kinase	0	3.23	--	DIRECT
Enzyme Commission (EC)	D-glycero-beta-D-manno-heptose-7-phosphate kinase	0	2.929	--	DIRECT
Enzyme Commission (EC)	Fructokinase	0	2.929	--	DIRECT
Enzyme Commission (EC)	5-dehydro-2-deoxygluconokinase	0	3.23	--	DIRECT
Enzyme Commission (EC)	D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase	0	2.929	--	DIRECT
Enzyme Commission (EC)	Ribokinase	0.00000000000004677	3.23	--	DIRECT
Enzyme Commission (EC)	Adenosine kinase	0.00000000000004677	3.23	--	DIRECT
Enzyme Commission (EC)	1-phosphofructokinase	0.0000000001593	3.23	--	DIRECT
Enzyme Commission (EC)	2-dehydro-3-deoxygluconokinase	0.000000009231	3.23	--	DIRECT
Enzyme Commission (EC)	Fructoselysine 6-kinase	0.00003117	3.23	--	DIRECT
Enzyme Commission (EC)	Ketohexokinase	0.00003117	3.23	--	DIRECT
Enzyme Commission (EC)	Inositol 3-kinase	0.00003117	3.23	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0.3972	Least Informative	DIRECT
Enzyme Commission (EC)	Phosphotransferases with an alcohol group as acceptor	0	1.238	Moderately Informative	DIRECT
Enzyme Commission (EC)	Nucleotidyltransferases	0.0000004709	1.126	Moderately Informative	DIRECT

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