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Yeast Phenotype (YP): cellular processes 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| SNARE-like | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| YjgF-like | 0 | DIRECT |
| Fumarate reductase respiratory complex transmembrane subunits | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Ribosomal protein S2 | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| DNA repair protein MutS, domain II | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| RNI-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| CorA soluble domain-like | 0 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| post-HMGL domain-like | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0.1415 | INHERITED FROM: osmotic stress resistance || cell cycle progression in G2 phase || ionic stress resistance || cell death |
| ARM repeat | 0.1885 | INHERITED FROM: protein transport |
| Nucleic acid-binding proteins | 0.2362 | INHERITED FROM: heat sensitivity || chromosome/plasmid maintenance || temperature sensitive growth || cell cycle progression |
| "Winged helix" DNA-binding domain | 0.2955 | INHERITED FROM: chromosome/plasmid maintenance || cell cycle progression |
| Class II aaRS and biotin synthetases | 0.3265 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| Ankyrin repeat | 0.3641 | INHERITED FROM: cell cycle progression through the G2/M phase transition |
| Translation proteins SH3-like domain | 0.4095 | INHERITED FROM: heat sensitivity |
| P-loop containing nucleoside triphosphate hydrolases | 0.5556 | INHERITED FROM: chromosome/plasmid maintenance || mutation frequency |
| GroEL apical domain-like | 0.5945 | INHERITED FROM: chromosome/plasmid maintenance |
| SH3-domain | 0.6407 | INHERITED FROM: intracellular transport |
| Histone-fold | 0.6407 | INHERITED FROM: cell cycle progression in G2 phase |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7955 | INHERITED FROM: starvation resistance |
| Cyclophilin-like | 0.9067 | INHERITED FROM: freeze-thaw resistance |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| SNARE-like | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| YjgF-like | 0 | Direct |
| Fumarate reductase respiratory complex transmembrane subunits | 0 | Direct |
| HIT-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| eIF1-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| KA1-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| HRDC-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| R3H domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| SAP domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| WW domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Cupredoxins | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| PA domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Acid proteases | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Ribosomal protein S2 | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| GYF domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| DNA repair protein MutS, domain II | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| Kelch motif | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Ras GEF | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| HMG-box | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Nop domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| RNI-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| CorA soluble domain-like | 0 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| post-HMGL domain-like | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Magnesium transport protein CorA, transmembrane region | 0 | Direct |
| CheY-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| L30e-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| vWA-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| POZ domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Cytochrome c | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| SET domain | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| HCP-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Protein kinase-like (PK-like) | 0.1415 | Inherited |
| ARM repeat | 0.1885 | Inherited |
| Nucleic acid-binding proteins | 0.2362 | Inherited |
| "Winged helix" DNA-binding domain | 0.2955 | Inherited |
| Class II aaRS and biotin synthetases | 0.3265 | Inherited |
| Ankyrin repeat | 0.3641 | Inherited |
| Translation proteins SH3-like domain | 0.4095 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.5556 | Inherited |
| GroEL apical domain-like | 0.5945 | Inherited |
| SH3-domain | 0.6407 | Inherited |
| Histone-fold | 0.6407 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7955 | Inherited |
| Cyclophilin-like | 0.9067 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| eIF1-like | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| PyrH-like | 0 | DIRECT |
| TRAPP components | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| FAD-linked oxidases, N-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| FAD/NAD-linked reductases, N-terminal and central domains | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Glycosyl hydrolases family 16 | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| CheY-related | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| Lysophospholipase | 0 | DIRECT |
| RING finger domain, C3HC4 | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| PHD domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Multidomain cupredoxins | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Thiamin biosynthesis kinases | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Ribosomal protein L14e | 0 | DIRECT |
| Tetratricopeptide repeat (TPR) | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| C-terminal domain of ribosomal protein L2 | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| CorA soluble domain-like | 0 | DIRECT |
| Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Trehalose-6-phosphate synthase, OtsA | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| YjgF/L-PSP | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| Ribosomal protein S13 | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Ubiquitin-related | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Bacteriorhodopsin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Ribosomal protein S2 | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| La domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Folylpolyglutamate synthetase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Ribosomal protein S4 | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| ENTH domain | 0 | DIRECT |
| Forkhead DNA-binding domain | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Vacuolar sorting protein domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Tryptophan biosynthesis enzymes | 0 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
| DJ-1/PfpI | 0 | DIRECT |
| Ran-binding domain | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| Gastric lipase | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.04864 | INHERITED FROM: radiation resistance |
| Protein kinases, catalytic subunit | 0.16 | INHERITED FROM: osmotic stress resistance || cell cycle progression in G2 phase || cell death |
| Cold shock DNA-binding domain-like | 0.3394 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| Ankyrin repeat | 0.3606 | INHERITED FROM: cell cycle progression through the G2/M phase transition |
| Glutathione peroxidase-like | 0.6091 | INHERITED FROM: oxidative stress resistance |
| SH3-domain | 0.639 | INHERITED FROM: intracellular transport |
| Thioltransferase | 0.683 | INHERITED FROM: oxidative stress resistance |
| 5' to 3' exonuclease catalytic domain | 0.7823 | INHERITED FROM: starvation resistance |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.7823 | INHERITED FROM: transposable element transposition |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7823 | INHERITED FROM: starvation resistance |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0.8217 | INHERITED FROM: hyperosmotic stress resistance || osmotic stress resistance |
| G proteins | 0.8866 | INHERITED FROM: autophagy |
| Cyclophilin (peptidylprolyl isomerase) | 0.9337 | INHERITED FROM: freeze-thaw resistance |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.9392 | INHERITED FROM: prion state || prion formation |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| eIF1-like | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| PyrH-like | 0 | Direct |
| TRAPP components | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| FAD-linked oxidases, N-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| HCP-like | 0 | Direct |
| FAD/NAD-linked reductases, N-terminal and central domains | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Hexokinase | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| MPP-like | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Glycosyl hydrolases family 16 | 0 | Direct |
| PUA domain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| NagB-like | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| CheY-related | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| HMGL-like | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| Lysophospholipase | 0 | Direct |
| RING finger domain, C3HC4 | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| PHD domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| FHA domain | 0 | Direct |
| Multidomain cupredoxins | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Thiamin biosynthesis kinases | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Class I aldolase | 0 | Direct |
| PA domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Ribosomal protein L14e | 0 | Direct |
| Tetratricopeptide repeat (TPR) | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| FabD-like | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| VHS domain | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| C-terminal domain of ribosomal protein L2 | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Subtilases | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| CorA soluble domain-like | 0 | Direct |
| Magnesium transport protein CorA, transmembrane region | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Trehalose-6-phosphate synthase, OtsA | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| PR-1-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| YjgF/L-PSP | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| UBC-related | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| PDI-like | 0 | Direct |
| Ribosomal protein S13 | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Ubiquitin-related | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Bacteriorhodopsin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| ALDH-like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Ribosomal protein S2 | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| La domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Folylpolyglutamate synthetase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Thiolase-related | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| WW domain | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| HMG-box | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Ribosomal protein S4 | 0 | Direct |
| UBA domain | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| ENTH domain | 0 | Direct |
| Forkhead DNA-binding domain | 0 | Direct |
| GAPDH-like | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| GYF domain | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Vacuolar sorting protein domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Ras GEF | 0 | Direct |
| Tryptophan biosynthesis enzymes | 0 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
| DJ-1/PfpI | 0 | Direct |
| Ran-binding domain | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Pepsin-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Reductases | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| Gastric lipase | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Tandem AAA-ATPase domain | 0.04864 | Inherited |
| Protein kinases, catalytic subunit | 0.16 | Inherited |
| Cold shock DNA-binding domain-like | 0.3394 | Inherited |
| Ankyrin repeat | 0.3606 | Inherited |
| Glutathione peroxidase-like | 0.6091 | Inherited |
| SH3-domain | 0.639 | Inherited |
| Thioltransferase | 0.683 | Inherited |
| 5' to 3' exonuclease catalytic domain | 0.7823 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.7823 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7823 | Inherited |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0.8217 | Inherited |
| G proteins | 0.8866 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 0.9337 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.9392 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| YjgF-like | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Fumarate reductase respiratory complex transmembrane subunits | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Ribosomal protein S2 | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| CorA soluble domain-like | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| RNI-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | DIRECT |
| DNA repair protein MutS, domain II | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| post-HMGL domain-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0.1295 | INHERITED FROM: cell cycle progression in G2 phase || cell death || ionic stress resistance || osmotic stress resistance |
| ARM repeat | 0.1749 | INHERITED FROM: protein transport |
| Nucleic acid-binding proteins | 0.2215 | INHERITED FROM: chromosome segregation || chromosome/plasmid maintenance || temperature sensitive growth || heat sensitivity || cell cycle progression |
| "Winged helix" DNA-binding domain | 0.2797 | INHERITED FROM: chromosome/plasmid maintenance || cell cycle progression |
| Class II aaRS and biotin synthetases | 0.3106 | INHERITED FROM: temperature sensitive growth || heat sensitivity |
| Ankyrin repeat | 0.3472 | INHERITED FROM: cell cycle progression through the G2/M phase transition |
| Translation proteins SH3-like domain | 0.3917 | INHERITED FROM: heat sensitivity |
| ENTH/VHS domain | 0.4364 | INHERITED FROM: intracellular transport |
| P-loop containing nucleoside triphosphate hydrolases | 0.5395 | INHERITED FROM: chromosome/plasmid maintenance || mutation frequency |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.5477 | INHERITED FROM: ionic stress resistance |
| GroEL apical domain-like | 0.5792 | INHERITED FROM: chromosome/plasmid maintenance |
| Histone-fold | 0.6262 | INHERITED FROM: cell cycle progression in G2 phase |
| SH3-domain | 0.6262 | INHERITED FROM: intracellular transport |
| Nucleotidyltransferase | 0.7505 | INHERITED FROM: temperature sensitive growth |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7869 | INHERITED FROM: starvation resistance |
| Cyclophilin-like | 0.8993 | INHERITED FROM: freeze-thaw resistance |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Cytochrome c | 0 | Direct |
| PA domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| YjgF-like | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| GYF domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| HIT-like | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Fumarate reductase respiratory complex transmembrane subunits | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Ribosomal protein S2 | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Aldolase | 0 | Direct |
| CorA soluble domain-like | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| CheY-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| HRDC-like | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| RNI-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| Acid proteases | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| WW domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| POZ domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | Direct |
| DNA repair protein MutS, domain II | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| SET domain | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| L30e-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| R3H domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Kelch motif | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| PR-1-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| SAP domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Nop domain | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Bromodomain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
| SNARE-like | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| eIF1-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| vWA-like | 0 | Direct |
| PUA domain-like | 0 | Direct |
| HMG-box | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| post-HMGL domain-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| KA1-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Magnesium transport protein CorA, transmembrane region | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| HCP-like | 0 | Direct |
| Protein kinase-like (PK-like) | 0.1295 | Inherited |
| ARM repeat | 0.1749 | Inherited |
| Nucleic acid-binding proteins | 0.2215 | Inherited |
| "Winged helix" DNA-binding domain | 0.2797 | Inherited |
| Class II aaRS and biotin synthetases | 0.3106 | Inherited |
| Ankyrin repeat | 0.3472 | Inherited |
| Translation proteins SH3-like domain | 0.3917 | Inherited |
| ENTH/VHS domain | 0.4364 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.5395 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.5477 | Inherited |
| GroEL apical domain-like | 0.5792 | Inherited |
| Histone-fold | 0.6262 | Inherited |
| SH3-domain | 0.6262 | Inherited |
| Nucleotidyltransferase | 0.7505 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7869 | Inherited |
| Cyclophilin-like | 0.8993 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | DIRECT |
50249,50104
50249 - Nucleic acid-binding proteins
50104 - Translation proteins SH3-like domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49503,49503
49503 - Cupredoxins
49503 - Cupredoxins | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
-9,52954
-9 - PDB
52954 - Class II aaRS ABD-related | 0 | DIRECT |
-9,-9
-9 - PDB
-9 - PDB | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
54747,46906
54747 - Ribosomal L11/L12e N-terminal domain
46906 - Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | DIRECT |
54631,51412
54631 - CBS-domain pair
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
81995,82919
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24 | 0 | DIRECT |
48371,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
56235,52402
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
56053,56053
56053 - Ribosomal protein L6
56053 - Ribosomal protein L6 | 0 | DIRECT |
54236,57829
54236 - Ubiquitin-like
57829 - Zn-binding ribosomal proteins | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
53150,48334
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
143865,144083
143865 - CorA soluble domain-like
144083 - Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2545 | INHERITED FROM: gamma ray resistance |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | Direct |
50249,50104
50249 - Nucleic acid-binding proteins
50104 - Translation proteins SH3-like domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
49503,49503
49503 - Cupredoxins
49503 - Cupredoxins | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
-9,52954
-9 - PDB
52954 - Class II aaRS ABD-related | 0 | Direct |
-9,-9
-9 - PDB
-9 - PDB | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
54747,46906
54747 - Ribosomal L11/L12e N-terminal domain
46906 - Ribosomal protein L11, C-terminal domain | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | Direct |
54631,51412
54631 - CBS-domain pair
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
81995,82919
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24 | 0 | Direct |
48371,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
56235,52402
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
56053,56053
56053 - Ribosomal protein L6
56053 - Ribosomal protein L6 | 0 | Direct |
54236,57829
54236 - Ubiquitin-like
57829 - Zn-binding ribosomal proteins | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
53150,48334
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
143865,144083
143865 - CorA soluble domain-like
144083 - Magnesium transport protein CorA, transmembrane region | 0 | Direct |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2545 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
49503,49503,49503
49503 - Cupredoxins
49503 - Cupredoxins
49503 - Cupredoxins | 0 | DIRECT |
49562,49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
81995,82919,53300
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57756,57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48371,52540,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53150,48334,52540
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
49503,49503,49503
49503 - Cupredoxins
49503 - Cupredoxins
49503 - Cupredoxins | 0 | Direct |
49562,49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
81995,82919,53300
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
57756,57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48371,52540,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53150,48334,52540
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this YP term
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Plot tree as:
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Download Newick format tree:
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Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this YP term
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Plot tree as:
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Download Newick format tree:
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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> BO Hierarchy > cellular processes
