Domain combination pairs in Clostridium acetobutylicum ATCC 824

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

697 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	29	12
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	26	8
CheY-like	C-terminal effector domain of the bipartite response regulators	20	2
Actin-like ATPase domain	Actin-like ATPase domain	19	8
"Winged helix" DNA-binding domain	Periplasmic binding protein-like II	14	1
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	12	2
(Trans)glycosidases	Glycosyl hydrolase domain	12	9
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	12	3
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	12	2
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	11	5
HAMP domain-like	Homodimeric domain of signal transducing histidine kinase	11	2
TPR-like	TPR-like	11	3
Invasin/intimin cell-adhesion fragments	Invasin/intimin cell-adhesion fragments	11	6
HAMP domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	11	2
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	11	4
Homeodomain-like	Tetracyclin repressor-like, C-terminal domain	10	1
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	10	7
Sensory domain-like	Methyl-accepting chemotaxis protein (MCP) signaling domain	9	3
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	9	6
lambda repressor-like DNA-binding domains	TPR-like	9	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	8	4
Penicillin binding protein dimerisation domain	beta-lactamase/transpeptidase-like	8	5
"Winged helix" DNA-binding domain	NagB/RpiA/CoA transferase-like	8	1
lambda repressor-like DNA-binding domains	Periplasmic binding protein-like I	7	1
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	6	3
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	6	4
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	6	6
Thiolase-like	Thiolase-like	6	1
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	6	3
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	6	1
Metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	6	4
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	6	1
Translation proteins	EF-G C-terminal domain-like	6	4
PGBD-like	PGBD-like	6	3
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	6	3
Invasin/intimin cell-adhesion fragments	L domain-like	6	4
Regulatory protein AraC	Homeodomain-like	6	3
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	5	4
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	5	4
Calcium ATPase, transduction domain A	HAD-like	5	4
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	5	2
Homeodomain-like	Homeodomain-like	5	2
EF-G C-terminal domain-like	EF-G C-terminal domain-like	5	3
HAD-like	Calcium ATPase, transmembrane domain M	5	4
Alpha-L RNA-binding motif	Pseudouridine synthase	5	1
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	5	3
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	5	4
Six-hairpin glycosidases	Type I dockerin domain	5	4
PTS-regulatory domain, PRD	PTS-regulatory domain, PRD	5	2
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	4	2
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	4	2
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	4	1
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	4	1
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	4	2
(Trans)glycosidases	PGBD-like	4	1
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	4	3
MFS general substrate transporter	MFS general substrate transporter	4	2
Homeodomain-like	SIS domain	4	1
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	4	3
Ferritin-like	Rubredoxin-like	4	2
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	4	4
Nucleic acid-binding proteins	Nucleic acid-binding proteins	4	4
RuvA domain 2-like	Nucleic acid-binding proteins	4	3
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	4	1
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	4	1
SacY-like RNA-binding domain	PTS-regulatory domain, PRD	4	1
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	4	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	4	3
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	4	2
(Trans)glycosidases	Type I dockerin domain	4	3
Trypsin-like serine proteases	PDZ domain-like	4	3
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	3	2
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	3	1
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	3	3
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	3	1
Glucose permease domain IIB	Duplicated hybrid motif	3	2
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	3	3
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	TK C-terminal domain-like	3	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	3	2
Translation proteins	Ribosomal protein S5 domain 2-like	3	2
PurM N-terminal domain-like	PurM C-terminal domain-like	3	2
Nucleotide cyclase	EAL domain-like	3	3
(Trans)glycosidases	Galactose-binding domain-like	3	3
PreATP-grasp domain	Rudiment single hybrid motif	3	2
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	3	1
GreA transcript cleavage protein, N-terminal domain	FKBP-like	3	1
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	3	2
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	3	2
"Winged helix" DNA-binding domain	GntR ligand-binding domain-like	3	1
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	3	3
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	3	2
"Winged helix" DNA-binding domain	Chorismate lyase-like	3	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	3	3
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	3	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	3	1
Galactose mutarotase-like	(Trans)glycosidases	3	2
Galactose mutarotase-like	Glycosyl hydrolase domain	3	2
tRNA-binding arm	Class II aaRS and biotin synthetases	3	1
cAMP-binding domain-like	"Winged helix" DNA-binding domain	3	1
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	3	3
ACT-like	ACT-like	3	2
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	3	1
4Fe-4S ferredoxins	FMN-dependent nitroreductase-like	3	1
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	Thiamin diphosphate-binding fold (THDP-binding)	3	2
(Trans)glycosidases	Ricin B-like lectins	3	2
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	3	1
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	3	3
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	3	1
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	3	3
Nucleotide-diphospho-sugar transferases	Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain	3	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	3	1
PYP-like sensor domain (PAS domain)	P-loop containing nucleoside triphosphate hydrolases	2	2
Galactose-binding domain-like	Galactose-binding domain-like	2	2
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	2	2
DNA ligase/mRNA capping enzyme, catalytic domain	RuvA domain 2-like	2	1
Class I glutamine amidotransferase-like	LD-carboxypeptidase A C-terminal domain-like	2	1
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	2	1
P-loop containing nucleoside triphosphate hydrolases	MOP-like	2	1
L domain-like	L domain-like	2	1
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	2	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	2	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	2	1
Histidine-containing phosphotransfer domain, HPT domain	CheY-binding domain of CheA	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheW-like	2	2
Glutamine synthetase/guanido kinase	GatB/YqeY motif	2	1
Integrin alpha N-terminal domain	Cysteine proteinases	2	2
alpha-helical ferredoxin	Nucleotide-binding domain	2	1
4Fe-4S ferredoxins	Fe-only hydrogenase	2	2
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	2	1
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	2	1
Phospholipase D/nuclease	Phospholipase D/nuclease	2	2
MurCD N-terminal domain	MurD-like peptide ligases, peptide-binding domain	2	1
Nucleotide-diphospho-sugar transferases	UDP-Glycosyltransferase/glycogen phosphorylase	2	1
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	2	2
PK beta-barrel domain-like	PK C-terminal domain-like	2	1
"Winged helix" DNA-binding domain	Dimeric alpha+beta barrel	2	1
"Winged helix" DNA-binding domain	Actin-like ATPase domain	2	1
Nucleic acid-binding proteins	Translation proteins SH3-like domain	2	2
Protein kinase-like (PK-like)	TPR-like	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	2
Glycosyl hydrolase domain	Galactose-binding domain-like	2	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	2	1
Glycosyl hydrolase domain	Ricin B-like lectins	2	1
Galactose mutarotase-like	Six-hairpin glycosidases	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	2	1
Homodimeric domain of signal transducing histidine kinase	CheW-like	2	2
P-loop containing nucleoside triphosphate hydrolases	TPR-like	2	2
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	2	2
TK C-terminal domain-like	4Fe-4S ferredoxins	2	1
Translation proteins	ThrRS/AlaRS common domain	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	2	2
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	2	1
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	2	1
CheY-binding domain of CheA	CheW-like	2	2
Six-hairpin glycosidases	Carbohydrate-binding domain	2	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	2	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	2	1
GAF domain-like	"Winged helix" DNA-binding domain	2	2
Nucleic acid-binding proteins	BRCT domain	2	1
Arabinanase/levansucrase/invertase	Ricin B-like lectins	2	2
CheC-like	Surface presentation of antigens (SPOA)	2	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	2	2
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	2	2
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	2	2
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	2	2
FAD/NAD(P)-binding domain	HI0933 insert domain-like	2	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	2	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	2	1
beta-lactamase/transpeptidase-like	Penicillin-binding protein associated domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	2	2
CheY-binding domain of CheA	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
GIY-YIG endonuclease	C-terminal UvrC-binding domain of UvrB	2	2
L,D-transpeptidase catalytic domain-like	PGBD-like	2	2
Aldolase	post-HMGL domain-like	2	2
LysM domain	LysM domain	2	2
"Winged helix" DNA-binding domain	PLP-dependent transferases	2	1
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	2	2
FucI/AraA N-terminal and middle domains	FucI/AraA C-terminal domain-like	2	1
Histidine-containing phosphotransfer domain, HPT domain	Homodimeric domain of signal transducing histidine kinase	2	2
PYP-like sensor domain (PAS domain)	Homeodomain-like	2	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	2	1
Cysteine proteinases	Tricorn protease N-terminal domain	2	1
"Winged helix" DNA-binding domain	Iron-dependent repressor protein, dimerization domain	2	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	2	1
Invasin/intimin cell-adhesion fragments	Cysteine proteinases	2	1
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	2	2
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	4Fe-4S ferredoxins	2	1
PUA domain-like	Ribosomal protein S5 domain 2-like	2	1
Glucocorticoid receptor-like (DNA-binding domain)	P-loop containing nucleoside triphosphate hydrolases	2	2
Invasin/intimin cell-adhesion fragments	Tricorn protease N-terminal domain	2	1
ALDH-like	Dehydroquinate synthase-like	2	1
Histidine-containing phosphotransfer domain, HPT domain	CheW-like	2	2
Pectin lyase-like	Pectin lyase-like	2	1
Carbohydrate-binding domain	Type I dockerin domain	2	1
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Nucleotide cyclase	GAF domain-like	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	2
Histidine-containing phosphotransfer domain, HPT domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	2	2
Thiamin diphosphate-binding fold (THDP-binding)	4Fe-4S ferredoxins	2	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	2	1
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	2	1
YrdC/RibB	Actin-like ATPase domain	2	2
Integrin alpha N-terminal domain	Integrin alpha N-terminal domain	2	2
L30e-like	alpha/beta knot	2	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	2	1
Nucleotide-binding domain	Nucleotide-binding domain	2	1
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Metallo-hydrolase/oxidoreductase	Flavoproteins	2	1
MurCD N-terminal domain	MurD-like peptide ligases, catalytic domain	2	1
HD-domain/PDEase-like	HD-domain/PDEase-like	2	1
Arabinanase/levansucrase/invertase	Galactose-binding domain-like	2	2
RuvA domain 2-like	BRCT domain	2	1
CheY-binding domain of CheA	Homodimeric domain of signal transducing histidine kinase	2	2
Chemotaxis receptor methyltransferase CheR, N-terminal domain	S-adenosyl-L-methionine-dependent methyltransferases	2	1
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	2	2
FKBP-like	Triger factor/SurA peptide-binding domain-like	2	2
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	2	1
MetI-like	Periplasmic binding protein-like II	2	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	2	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	2	2
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	2	2
HAD-like	Acyl-CoA N-acyltransferases (Nat)	2	1
Nucleotide-diphospho-sugar transferases	PilZ domain-like	2	1
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	2	1
Carbamate kinase-like	ACT-like	2	1
HMA, heavy metal-associated domain	HAD-like	2	2
NAD(P)-linked oxidoreductase	alpha-helical ferredoxin	2	1
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	2	1
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
Methionine synthase domain	Cobalamin (vitamin B12)-binding domain	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	1	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	1	1
LigB-like	AMMECR1-like	1	1
2Fe-2S ferredoxin-like	Fe-only hydrogenase	1	1
HD-domain/PDEase-like	Nucleotidyltransferase	1	1
HD-domain/PDEase-like	TGS-like	1	1
GroES-like	NAD(P)-binding Rossmann-fold domains	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	1	1
Phage fibre proteins	Ricin B-like lectins	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Resolvase-like	BAR/IMD domain-like	1	1
alpha/beta-Hydrolases	Invasin/intimin cell-adhesion fragments	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
GroEL equatorial domain-like	GroEL apical domain-like	1	1
Adenine nucleotide alpha hydrolases-like	MesJ substrate recognition domain-like	1	1
Galactose-binding domain-like	E set domains	1	1
P-loop containing nucleoside triphosphate hydrolases	TGS-like	1	1
lambda repressor-like DNA-binding domains	LexA/Signal peptidase	1	1
"Winged helix" DNA-binding domain	PRTase-like	1	1
"Winged helix" DNA-binding domain	PTS system fructose IIA component-like	1	1
PDZ domain-like	Radical SAM enzymes	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
Nucleic acid-binding proteins	HD-domain/PDEase-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Galactose-binding domain-like	Type I dockerin domain	1	1
Transcription factor NusA, N-terminal domain	Prokaryotic type KH domain (KH-domain type II)	1	1
(Trans)glycosidases	Invasin/intimin cell-adhesion fragments	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
Ribonuclease H-like	DNA/RNA polymerases	1	1
DnaD domain-like	DnaD domain-like	1	1
Actin-like ATPase domain	HD-domain/PDEase-like	1	1
Putative DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Thiolase-like	FabD/lysophospholipase-like	1	1
post-HMGL domain-like	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
Rho N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	1	1
Flavoproteins	Flavoproteins	1	1
PreATP-grasp domain	Single hybrid motif	1	1
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	1	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Penicillin binding protein dimerisation domain	Penicillin-binding protein 2x (pbp-2x), c-terminal domain	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
LysM domain	(Trans)glycosidases	1	1
PGBD-like	Hedgehog/DD-peptidase	1	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	1	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	1	1
"Winged helix" DNA-binding domain	TrkA C-terminal domain-like	1	1
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD	CoaB-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	1	1
Nudix	Nudix	1	1
HprK N-terminal domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
beta-lactamase/transpeptidase-like	Penicillin-binding protein 2x (pbp-2x), c-terminal domain	1	1
"Winged helix" DNA-binding domain	HprK N-terminal domain-like	1	1
Homocysteine S-methyltransferase	Dihydropteroate synthetase-like	1	1
Nucleotide-diphospho-sugar transferases	Phosphoglucomutase, C-terminal domain	1	1
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	1	1
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Acylphosphatase/BLUF domain-like	Actin-like ATPase domain	1	1
PreATP-grasp domain	Aldolase	1	1
4Fe-4S ferredoxins	Adenine nucleotide alpha hydrolases-like	1	1
Dihydropteroate synthetase-like	Methionine synthase domain	1	1
"Winged helix" DNA-binding domain	NAD(P)-binding Rossmann-fold domains	1	1
NAD(P)-binding Rossmann-fold domains	Nucleotide-binding domain	1	1
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	1	1
Zinc beta-ribbon	DNA primase core	1	1
(Trans)glycosidases	Putative glucosidase YicI, C-terminal domain	1	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	1	1
MoeA C-terminal domain-like	Periplasmic binding protein-like II	1	1
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Invasin/intimin cell-adhesion fragments	Class I glutamine amidotransferase-like	1	1
Trimeric LpxA-like enzymes	Phosphoglucomutase, C-terminal domain	1	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
P-loop containing nucleoside triphosphate hydrolases	C-terminal effector domain of the bipartite response regulators	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	1	1
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	Multidrug efflux transporter AcrB transmembrane domain	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	1	1
FliG	FliG	1	1
Transcription factor NusA, N-terminal domain	Nucleic acid-binding proteins	1	1
"Helical backbone" metal receptor	Radical SAM enzymes	1	1
GroEL-intermediate domain like	GroEL apical domain-like	1	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	1	1
Ribonuclease H-like	BRCT domain	1	1
Translation proteins	Initiation factor IF2/eIF5b, domain 3	1	1
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	1	1
E set domains	Six-hairpin glycosidases	1	1
Nucleic acid-binding proteins	Anticodon-binding domain of PheRS	1	1
DnaK suppressor protein DksA, alpha-hairpin domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Prokaryotic type I DNA topoisomerase	Zinc beta-ribbon	1	1
Rudiment single hybrid motif	post-HMGL domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	1	1
FAD-binding/transporter-associated domain-like	Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain	1	1
Cation efflux protein cytoplasmic domain-like	Cation efflux protein cytoplasmic domain-like	1	1
THUMP domain-like	Adenine nucleotide alpha hydrolases-like	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
HPr-like	PYP-like sensor domain (PAS domain)	1	1
DeoB insert domain-like	Alkaline phosphatase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Restriction endonuclease-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	1	1
P-loop containing nucleoside triphosphate hydrolases	Homodimeric domain of signal transducing histidine kinase	1	1
Homocysteine S-methyltransferase	FAD-linked oxidoreductase	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
Nucleic acid-binding proteins	PheT/TilS domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PTS system fructose IIA component-like	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	NAD(P)-binding Rossmann-fold domains	1	1
P-loop containing nucleoside triphosphate hydrolases	GAF domain-like	1	1
PDZ domain-like	ClpP/crotonase	1	1
Concanavalin A-like lectins/glucanases	Glycosyl hydrolase domain	1	1
Cytidine deaminase-like	Dihydrofolate reductase-like	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Galactose-binding domain-like	Six-hairpin glycosidases	1	1
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	1	1
HPr-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
Galactose mutarotase-like	Galactose mutarotase-like	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
PIN domain-like	DNA/RNA polymerases	1	1
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	1	1
PheT/TilS domain	Putative DNA-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	TrpR-like	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
Trimeric LpxA-like enzymes	Phosphoglucomutase, first 3 domains	1	1
Aspartate/glutamate racemase	Aspartate/glutamate racemase	1	1
YojJ-like	RuvA domain 2-like	1	1
GyrA/ParC C-terminal domain-like	GyrA/ParC C-terminal domain-like	1	1
YhbC-like, N-terminal domain	YhbC-like, C-terminal domain	1	1
CbiG N-terminal domain-like	CobE/GbiG C-terminal domain-like	1	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	1	1
"Winged helix" DNA-binding domain	LexA/Signal peptidase	1	1
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
Integrin alpha N-terminal domain	Lysozyme-like	1	1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain	Phosphohistidine domain	1	1
Molybdenum cofactor biosynthesis proteins	CinA-like	1	1
"Winged helix" DNA-binding domain	CBS-domain pair	1	1
5' to 3' exonuclease, C-terminal subdomain	Ribonuclease H-like	1	1
Methionine synthase domain	Methionine synthase activation domain-like	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
HPr-like	Homeodomain-like	1	1
Concanavalin A-like lectins/glucanases	Invasin/intimin cell-adhesion fragments	1	1
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	1	1
Trigger factor ribosome-binding domain	FKBP-like	1	1
RuvA domain 2-like	P-loop containing nucleoside triphosphate hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	C-terminal UvrC-binding domain of UvrB	1	1
Dihydropteroate synthetase-like	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
GIY-YIG endonuclease	RuvA domain 2-like	1	1
GroEL equatorial domain-like	GroEL-intermediate domain like	1	1
PPK N-terminal domain-like	PHP14-like	1	1
TPR-like	GAF domain-like	1	1
Galactose-binding domain-like	Ricin B-like lectins	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
Thiolase-like	NAD(P)-binding Rossmann-fold domains	1	1
Putative DNA-binding domain	Anticodon-binding domain of PheRS	1	1
all-alpha NTP pyrophosphatases	all-alpha NTP pyrophosphatases	1	1
Nucleic acid-binding proteins	DNA helicase RuvA subunit, C-terminal domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	1	1
PTS system IIB component-like	Phoshotransferase/anion transport protein	1	1
Nudix	"Winged helix" DNA-binding domain	1	1
4Fe-4S ferredoxins	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Thiolase-like	ACP-like	1	1
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
Dihydropteroate synthetase-like	Methionine synthase activation domain-like	1	1
"Winged helix" DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PTS-regulatory domain, PRD	1	1
Tropomyosin	Smc hinge domain	1	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	1	1
Homocysteine S-methyltransferase	Methionine synthase activation domain-like	1	1
HD-domain/PDEase-like	ACT-like	1	1
Chaperone J-domain	TPR-like	1	1
NAD(P)-binding Rossmann-fold domains	ACT-like	1	1
Rudiment single hybrid motif	Single hybrid motif	1	1
PreATP-grasp domain	post-HMGL domain-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	1	1
Ligand-binding domain in the NO signalling and Golgi transport	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
Flavoproteins	4Fe-4S ferredoxins	1	1
MesJ substrate recognition domain-like	PheT/TilS domain	1	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	1	1
PTS-regulatory domain, PRD	PTS system fructose IIA component-like	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Type I dockerin domain	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
Tetrapyrrole methylase	HemD-like	1	1
Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	1	1
C-terminal UvrC-binding domain of UvrB	RuvA domain 2-like	1	1
Chorismate mutase II	NAD(P)-binding Rossmann-fold domains	1	1
"Winged helix" DNA-binding domain	PTS-regulatory domain, PRD	1	1
CheY-like	Methylesterase CheB, C-terminal domain	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
DNA clamp	DNA clamp	1	1
Nucleic acid-binding proteins	ArfGap/RecO-like zinc finger	1	1
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	1	1
PPK N-terminal domain-like	Phospholipase D/nuclease	1	1
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain	Phosphoenolpyruvate/pyruvate domain	1	1
N-terminal domain of DnaB helicase	P-loop containing nucleoside triphosphate hydrolases	1	1
Invasin/intimin cell-adhesion fragments	Type I dockerin domain	1	1
Acylphosphatase/BLUF domain-like	YrdC/RibB	1	1
Rho N-terminal domain-like	Nucleic acid-binding proteins	1	1
PrpR receptor domain-like	PYP-like sensor domain (PAS domain)	1	1
TPR-like	C-terminal effector domain of the bipartite response regulators	1	1
PreATP-grasp domain	PreATP-grasp domain	1	1
Nucleotidylyl transferase	tRNA-binding arm	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
Adenine nucleotide alpha hydrolases-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Putative DNA-binding domain	Antibiotic binding domain of TipA-like multidrug resistance regulators	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
Nucleic acid-binding proteins	Prokaryotic type KH domain (KH-domain type II)	1	1
MoeA N-terminal region -like	Periplasmic binding protein-like II	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
E set domains	E set domains	1	1
lambda repressor-like DNA-binding domains	lambda repressor-like DNA-binding domains	1	1
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
(Trans)glycosidases	Phage fibre proteins	1	1
CheW-like	CheY-like	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	1	1
Periplasmic binding protein-like II	ACT-like	1	1
Beta-galactosidase LacA, domain 3	Galactose-binding domain-like	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	1	1
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	1	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	1	1
"Winged helix" DNA-binding domain	Periplasmic binding protein-like I	1	1
4Fe-4S ferredoxins	DHS-like NAD/FAD-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	CBS-domain pair	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
L,D-transpeptidase pre-catalytic domain-like	L,D-transpeptidase catalytic domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	1	1
EAL domain-like	Sensory domain-like	1	1
Tropomyosin	Lysozyme-like	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	HD-domain/PDEase-like	1	1
TGS-like	Class II aaRS ABD-related	1	1
P-loop containing nucleoside triphosphate hydrolases	Adenine nucleotide alpha hydrolases-like	1	1
Aldehyde ferredoxin oxidoreductase, N-terminal domain	Aldehyde ferredoxin oxidoreductase, C-terminal domains	1	1
Regulatory protein AraC	(Trans)glycosidases	1	1
CBS-domain pair	Nucleotide cyclase	1	1
YjeF N-terminal domain-like	Ribokinase-like	1	1
TrmE connector domain	P-loop containing nucleoside triphosphate hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Fibronectin type III	(Trans)glycosidases	1	1
Tetrapyrrole methylase	all-alpha NTP pyrophosphatases	1	1
Pentapeptide repeat-like	Galactose-binding domain-like	1	1
E set domains	(Trans)glycosidases	1	1
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	1	1
Homeodomain-like	Glycosyl hydrolase domain	1	1
NTF2-like	Penicillin binding protein dimerisation domain	1	1
Galactose mutarotase-like	Putative glucosidase YicI, C-terminal domain	1	1
CBS-domain pair	Thioesterase/thiol ester dehydrase-isomerase	1	1
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	1	1
Homocysteine S-methyltransferase	Cobalamin (vitamin B12)-binding domain	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Putative DNA-binding domain	Probable bacterial effector-binding domain	1	1
Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain	Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	1	1
PUA domain-like	alpha/beta knot	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	1	1
E set domains	Type I dockerin domain	1	1
Thymidylate synthase-complementing protein Thy1	Thymidylate synthase-complementing protein Thy1	1	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	1	1
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	1	1
Chorismate mutase II	Aminoacid dehydrogenase-like, N-terminal domain	1	1
Glycosyl hydrolase domain	Beta-galactosidase LacA, domain 3	1	1
Nucleotidylyl transferase	Riboflavin kinase-like	1	1
PrpR receptor domain-like	Homeodomain-like	1	1
Hsp33 domain	HSP33 redox switch-like	1	1
lambda repressor-like DNA-binding domains	RmlC-like cupins	1	1
HprK N-terminal domain-like	PEP carboxykinase-like	1	1
Fibronectin type III	Pectin lyase-like	1	1
Ricin B-like lectins	Ricin B-like lectins	1	1
Protein kinase-like (PK-like)	Nucleotide cyclase	1	1
YbaK/ProRS associated domain	Class II aaRS ABD-related	1	1
Cell wall binding repeat	Cell wall binding repeat	1	1
Nucleotidyltransferase	ACT-like	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	ACT-like	1	1
TGS-like	ACT-like	1	1
Nitrite/Sulfite reductase N-terminal domain-like	4Fe-4S ferredoxins	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Nucleotide cyclase	1	1
FAD/NAD(P)-binding domain	ISP domain	1	1
Subtilisin-like	Subtilisin-like	1	1
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	1	1
Acid phosphatase/Vanadium-dependent haloperoxidase	Pectin lyase-like	1	1
NAD(P)-binding Rossmann-fold domains	GAF domain-like	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Nucleotide-diphospho-sugar transferases	Phosphoglucomutase, first 3 domains	1	1
Galactose-binding domain-like	Concanavalin A-like lectins/glucanases	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
PIN domain-like	Ribonuclease H-like	1	1
Copper amine oxidase, domain N	"Helical backbone" metal receptor	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
"Winged helix" DNA-binding domain	Thioesterase/thiol ester dehydrase-isomerase	1	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Homeodomain-like	Probable bacterial effector-binding domain	1	1
YrdC/RibB	RibA-like	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
"Helical backbone" metal receptor	Nitrogenase accessory factor-like	1	1
EAL domain-like	CBS-domain pair	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	1	1
Glycosyl hydrolase domain	Putative glucosidase YicI, C-terminal domain	1	1
RNase III domain-like	dsRNA-binding domain-like	1	1
Bacillus cereus metalloprotein-like	Bacillus cereus metalloprotein-like	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
Phospholipase C/P1 nuclease	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
post-HMGL domain-like	Single hybrid motif	1	1
TPR-like	Nucleotide cyclase	1	1
Aldolase	AFP III-like domain	1	1
ThrRS/AlaRS common domain	P-loop containing nucleoside triphosphate hydrolases	1	1
"Winged helix" DNA-binding domain	Putative transcriptional regulator TM1602, C-terminal domain	1	1
EspE N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
PTS-regulatory domain, PRD	Phoshotransferase/anion transport protein	1	1
P-loop containing nucleoside triphosphate hydrolases	CarD-like	1	1
Cobalamin (vitamin B12)-binding domain	Radical SAM enzymes	1	1
Class II aaRS and biotin synthetases	C-terminal domain of transcriptional repressors	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	1	1
Nucleic acid-binding proteins	Putative DNA-binding domain	1	1
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
Phospholipase D/nuclease	P-loop containing nucleoside triphosphate hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	1	1
L9 N-domain-like	Ribosomal protein L9 C-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
Methylated DNA-protein cysteine methyltransferase domain	Methylated DNA-protein cysteine methyltransferase, C-terminal domain	1	1
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	1	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Mechanosensitive channel protein MscS (YggB), C-terminal domain	1	1
Glutathione synthetase ATP-binding domain-like	Aldolase	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	ACP-like	1	1
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
HIT-like	HIT-like	1	1
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	1	1
Thiolase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Prokaryotic type KH domain (KH-domain type II)	Prokaryotic type KH domain (KH-domain type II)	1	1
Serine metabolism enzymes domain	ACT-like	1	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
Aconitase iron-sulfur domain	LeuD/IlvD-like	1	1
CarD-like	TRCF domain-like	1	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	1	1
CheY-like	CheC-like	1	1
5' to 3' exonuclease, C-terminal subdomain	DNA/RNA polymerases	1	1
HD-domain/PDEase-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
Heat shock protein 70kD (HSP70), peptide-binding domain	vWA-like	1	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB transmembrane domain	1	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
ParB/Sulfiredoxin	KorB DNA-binding domain-like	1	1
Class II aaRS and biotin synthetases	Translation proteins	1	1
Homeodomain-like	(Trans)glycosidases	1	1
Translation proteins	Translation proteins	1	1
FabD/lysophospholipase-like	ACP-like	1	1
PRTase-like	PRTase-like	1	1
Adenine nucleotide alpha hydrolases-like	Homodimeric domain of signal transducing histidine kinase	1	1
Class II aaRS and biotin synthetases	YbaK/ProRS associated domain	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	ACT-like	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	1	1
Cobalamin (vitamin B12)-binding domain	Methionine synthase activation domain-like	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Homocysteine S-methyltransferase	Methionine synthase domain	1	1
alpha/beta-Hydrolases	Ricin B-like lectins	1	1
Nucleotide-diphospho-sugar transferases	TPR-like	1	1
Carbohydrate-binding domain	Carbohydrate-binding domain	1	1
PRC-barrel domain	PRC-barrel domain	1	1
Radical SAM enzymes	Nitrogenase accessory factor-like	1	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	1	1
Lysozyme-like	beta-lactamase/transpeptidase-like	1	1
Actin-like ATPase domain	vWA-like	1	1
CheY-like	P-loop containing nucleoside triphosphate hydrolases	1	1
RuvA domain 2-like	DNA helicase RuvA subunit, C-terminal domain	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Glycosyl hydrolase domain	Type I dockerin domain	1	1
Dihydropteroate synthetase-like	Cobalamin (vitamin B12)-binding domain	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
FabD/lysophospholipase-like	NAD(P)-binding Rossmann-fold domains	1	1
Molybdenum cofactor biosynthesis proteins	Periplasmic binding protein-like II	1	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Penicillin-binding protein 2x (pbp-2x), c-terminal domain	Penicillin-binding protein 2x (pbp-2x), c-terminal domain	1	1
(Trans)glycosidases	Concanavalin A-like lectins/glucanases	1	1
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	1	1
PTS system fructose IIA component-like	PTS IIb component	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
Protein kinase-like (PK-like)	GAF domain-like	1	1
"Winged helix" DNA-binding domain	C-terminal domain of arginine repressor	1	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	1	1
NTF2-like	beta-lactamase/transpeptidase-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
PTS-regulatory domain, PRD	PTS system IIB component-like	1	1
NAD(P)-binding Rossmann-fold domains	ACP-like	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
PHP14-like	Phospholipase D/nuclease	1	1
Ribosomal protein L6	Ribosomal protein L6	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
Protease propeptides/inhibitors	Subtilisin-like	1	1
HprK N-terminal domain-like	CBS-domain pair	1	1
PheT/TilS domain	Anticodon-binding domain of PheRS	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Translation proteins	PRC-barrel domain	1	1
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Sm-like ribonucleoproteins	Mechanosensitive channel protein MscS (YggB), C-terminal domain	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
PrpR receptor domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	1	1
Aldolase	Single hybrid motif	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
Rudiment single hybrid motif	Aldolase	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	1	1
HAMP domain-like	PYP-like sensor domain (PAS domain)	1	1
RBP11-like subunits of RNA polymerase	C-terminal domain of RNA polymerase alpha subunit	1	1
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	1	1
Regulatory protein AraC	Glycosyl hydrolase domain	1	1
(Trans)glycosidases	Beta-galactosidase LacA, domain 3	1	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Radical SAM enzymes	RuvA domain 2-like	1	1
Adenine nucleotide alpha hydrolases-like	PheT/TilS domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
Carbohydrate-binding domain	E set domains	1	1
Nucleotidyltransferase	TGS-like	1	1
Insert subdomain of RNA polymerase alpha subunit	C-terminal domain of RNA polymerase alpha subunit	1	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1

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