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Zebrafish Anatomy (ZA): whole organism  
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: ZA Hierarchy (zebrafish anatomy from ZFIN zebrafish anatomy ontology)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DUSP-like | 0 | DIRECT |
| Lipocalins | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| Interleukin 8-like chemokines | 0 | DIRECT |
| Ubiquitin-like | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| C-type lectin-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| ARM repeat | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| EF-hand | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| Kazal-type serine protease inhibitors | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| p53-like transcription factors | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| LDL receptor-like module | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| PLP-dependent transferases | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| RNA-binding domain, RBD | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Homeodomain-like | 0 | DIRECT |
| UBA-like | 0 | DIRECT |
| Voltage-gated potassium channels | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Galactose-binding domain-like | 0 | DIRECT |
| FnI-like domain | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| TPR-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Orange domain-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| TNF-like | 0 | DIRECT |
| BPTI-like | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| 4-helical cytokines | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| MFS general substrate transporter | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| beta-beta-alpha zinc fingers | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| EGF/Laminin | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| (Trans)glycosidases | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| alpha/beta-Hydrolases | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| GTPase activation domain, GAP | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Thioredoxin-like | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| E set domains | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Cystine-knot cytokines | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Cysteine proteinases | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| WD40 repeat-like | 0.8511 | INHERITED FROM: photoreceptor outer segment layer || retinal outer nuclear layer |
| Immunoglobulin | 0.8511 | INHERITED FROM: white matter || olfactory bulb glomerulus || medial longitudinal fasciculus |
| Fibronectin type III | 0.8986 | INHERITED FROM: white matter || synencephalon || medial longitudinal fasciculus || glomerular layer |
| Concanavalin A-like lectins/glucanases | 0.9103 | INHERITED FROM: epidermis |
| Ankyrin repeat | 0.9513 | INHERITED FROM: radial glial cell |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DUSP-like | 0 | Direct |
| Lipocalins | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| PKD domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| F-box domain | 0 | Direct |
| Interleukin 8-like chemokines | 0 | Direct |
| Ubiquitin-like | 0 | Direct |
| HIT-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| ALDH-like | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| Integrin domains | 0 | Direct |
| C-type lectin-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| ADC-like | 0 | Direct |
| Connexin43 | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| TIMP-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| ARM repeat | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Translation proteins | 0 | Direct |
| EF-hand | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Caspase-like | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| MIR domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Cytokine | 0 | Direct |
| Kazal-type serine protease inhibitors | 0 | Direct |
| DEATH domain | 0 | Direct |
| NAD(P)-binding Rossmann-fold domains | 0 | Direct |
| Bromodomain | 0 | Direct |
| p53-like transcription factors | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Histone-fold | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| LDL receptor-like module | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| L27 domain | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| BRCT domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| PLP-dependent transferases | 0 | Direct |
| PP2C-like | 0 | Direct |
| GroES-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| RNA-binding domain, RBD | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| L domain-like | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Plakin repeat | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| GFP-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Homeodomain-like | 0 | Direct |
| UBA-like | 0 | Direct |
| Voltage-gated potassium channels | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Galactose-binding domain-like | 0 | Direct |
| FnI-like domain | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| UBC-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| SRF-like | 0 | Direct |
| LCCL domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| HMG-box | 0 | Direct |
| TPR-like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Kringle-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| PH domain-like | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| HAD-like | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| PGBD-like | 0 | Direct |
| WW domain | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Orange domain-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| NHL repeat | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| ACT-like | 0 | Direct |
| TNF-like | 0 | Direct |
| BPTI-like | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| GLA-domain | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| SH2 domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Kelch motif | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| Nicotinic receptor ligand binding domain-like | 0 | Direct |
| Aldolase | 0 | Direct |
| 4-helical cytokines | 0 | Direct |
| SNARE-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| SH3-domain | 0 | Direct |
| MFS general substrate transporter | 0 | Direct |
| SET domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| beta-beta-alpha zinc fingers | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| CalX-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| EGF/Laminin | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Insulin-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| (Trans)glycosidases | 0 | Direct |
| vWA-like | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| alpha/beta-Hydrolases | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| STAT | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| PX domain | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| GTPase activation domain, GAP | 0 | Direct |
| Sema domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| POZ domain | 0 | Direct |
| Ras GEF | 0 | Direct |
| Notch domain | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Thioredoxin-like | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| E set domains | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Cystine-knot cytokines | 0 | Direct |
| HCP-like | 0 | Direct |
| DNase I-like | 0 | Direct |
| Cyclin-like | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| (Phosphotyrosine protein) phosphatases II | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Cysteine proteinases | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| WD40 repeat-like | 0.8511 | Inherited |
| Immunoglobulin | 0.8511 | Inherited |
| Fibronectin type III | 0.8986 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.9103 | Inherited |
| Ankyrin repeat | 0.9513 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| SPRY domain | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Fibroblast growth factors (FGF) | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| EF-hand modules in multidomain proteins | 0 | DIRECT |
| N-acetyl transferase, NAT | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| PWWP domain | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Arrestin/Vps26-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| Platelet-derived growth factor-like | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Extended AAA-ATPase domain | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| G proteins | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| Motor proteins | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| L domain | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Classic zinc finger, C2H2 | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
| CalX-beta domain | 0 | DIRECT |
| LDL receptor-like module | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| MYND zinc finger | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Eukaryotic proteases | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Homeodomain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Anion transport protein, cytoplasmic domain | 0 | DIRECT |
| V set domains (antibody variable domain-like) | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Calmodulin-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| ABC transporter ATPase domain-like | 0 | DIRECT |
| PHD domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Small Kunitz-type inhibitors & BPTI-like toxins | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Transforming growth factor (TGF)-beta | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Penta-EF-hand proteins | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Hedgehog (development protein), N-terminal signaling domain | 0 | DIRECT |
| Plakophilin 1 helical region | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| TNF-like | 0 | DIRECT |
| Caspase recruitment domain, CARD | 0 | DIRECT |
| Rhodopsin-like | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| RUNT domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Integrin A (or I) domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Pyridoxal-dependent decarboxylase | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Hairy Orange domain | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Link domain | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Fibronectin type II module | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| Short-chain cytokines | 0 | DIRECT |
| p53 DNA-binding domain-like | 0 | DIRECT |
| T-box | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Nuclear receptor | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Tetratricopeptide repeat (TPR) | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Voltage-gated potassium channels | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| LIM domain | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Dachshund-homology domain | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Synaptotagmin-like (S variant) | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| VWC domain | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Forkhead DNA-binding domain | 0 | DIRECT |
| Tetramerization domain of potassium channels | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| C-type lectin domain | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Long-chain cytokines | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Flavin-binding PAS domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| L-arabinose binding protein-like | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| BTB/POZ domain | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Interleukin 8-like chemokines | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| Ubiquitin-related | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| STAT DNA-binding domain | 0 | DIRECT |
| BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Tyrosine-dependent oxidoreductases | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Pentraxin (pentaxin) | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| MMP N-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Ovomucoid domain III-like | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Canonical RBD | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| WD40-repeat | 0.9019 | INHERITED FROM: photoreceptor outer segment layer || retinal cone cell |
| Fibronectin type III | 0.9019 | INHERITED FROM: white matter || synencephalon || medial longitudinal fasciculus || glomerular layer |
| I set domains | 0.949 | INHERITED FROM: white matter || synencephalon || medial longitudinal fasciculus |
| Ankyrin repeat | 0.954 | INHERITED FROM: radial glial cell |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| SPRY domain | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Fibroblast growth factors (FGF) | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| SRF-like | 0 | Direct |
| EF-hand modules in multidomain proteins | 0 | Direct |
| N-acetyl transferase, NAT | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| GLA-domain | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Elongation factors | 0 | Direct |
| UBA domain | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| PWWP domain | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| Protein kinases, catalytic subunit | 0 | Direct |
| FCH domain | 0 | Direct |
| Arrestin/Vps26-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| NHL repeat | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| Platelet-derived growth factor-like | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| F-box domain | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Extended AAA-ATPase domain | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| G proteins | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| Motor proteins | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| L domain | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| Cadherin | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Laminin-type module | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Classic zinc finger, C2H2 | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
| CalX-beta domain | 0 | Direct |
| LDL receptor-like module | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| MYND zinc finger | 0 | Direct |
| BAR domain | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Eukaryotic proteases | 0 | Direct |
| L27 domain | 0 | Direct |
| Homeodomain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| PX domain | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Anion transport protein, cytoplasmic domain | 0 | Direct |
| V set domains (antibody variable domain-like) | 0 | Direct |
| Sema domain | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Calmodulin-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| ABC transporter ATPase domain-like | 0 | Direct |
| PHD domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Small Kunitz-type inhibitors & BPTI-like toxins | 0 | Direct |
| Tudor domain | 0 | Direct |
| PAZ domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Transforming growth factor (TGF)-beta | 0 | Direct |
| Paired domain | 0 | Direct |
| Penta-EF-hand proteins | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Hedgehog (development protein), N-terminal signaling domain | 0 | Direct |
| Plakophilin 1 helical region | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| TNF-like | 0 | Direct |
| Caspase recruitment domain, CARD | 0 | Direct |
| Rhodopsin-like | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| RUNT domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Integrin A (or I) domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Pyridoxal-dependent decarboxylase | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| PDZ domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Hairy Orange domain | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| CCHHC domain | 0 | Direct |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| STAT | 0 | Direct |
| Link domain | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| MIR domain | 0 | Direct |
| Fibronectin type II module | 0 | Direct |
| LCCL domain | 0 | Direct |
| Connexin43 | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| ets domain | 0 | Direct |
| CUT domain | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| Short-chain cytokines | 0 | Direct |
| p53 DNA-binding domain-like | 0 | Direct |
| T-box | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Nicotinic receptor ligand binding domain-like | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| Papain-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Troponin T | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Nuclear receptor | 0 | Direct |
| SH3-domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| SMAD domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Tetratricopeptide repeat (TPR) | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Voltage-gated potassium channels | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Chromo domain | 0 | Direct |
| LIM domain | 0 | Direct |
| PB1 domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Dachshund-homology domain | 0 | Direct |
| SH2 domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Synaptotagmin-like (S variant) | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| EGF-type module | 0 | Direct |
| Subtilases | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| VWC domain | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Forkhead DNA-binding domain | 0 | Direct |
| Tetramerization domain of potassium channels | 0 | Direct |
| YWTD domain | 0 | Direct |
| C-type lectin domain | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| MAPEG domain | 0 | Direct |
| PKD domain | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Plakin repeat | 0 | Direct |
| UBC-related | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Long-chain cytokines | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Flavin-binding PAS domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| L-arabinose binding protein-like | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| HMG-box | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| WW domain | 0 | Direct |
| BTB/POZ domain | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Interleukin 8-like chemokines | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| Ubiquitin-related | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| STAT DNA-binding domain | 0 | Direct |
| BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Tyrosine-dependent oxidoreductases | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Notch domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Kelch motif | 0 | Direct |
| Ras GEF | 0 | Direct |
| Pentraxin (pentaxin) | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| Tandem AAA-ATPase domain | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| FHA domain | 0 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| MMP N-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Ovomucoid domain III-like | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Canonical RBD | 0 | Direct |
| SWIRM domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| WD40-repeat | 0.9019 | Inherited |
| Fibronectin type III | 0.9019 | Inherited |
| I set domains | 0.949 | Inherited |
| Ankyrin repeat | 0.954 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| TPR-like | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| alpha/beta-Hydrolases | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| Ubiquitin-like | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| PLP-dependent transferases | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Interleukin 8-like chemokines | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| Lipocalins | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| 4-helical cytokines | 0 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| LDL receptor-like module | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| UBA-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| BPTI-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| EF-hand | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| TNF-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| MFS general substrate transporter | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
| Cysteine proteinases | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| GTPase activation domain, GAP | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Orange domain-like | 0 | DIRECT |
| beta-beta-alpha zinc fingers | 0 | DIRECT |
| ARM repeat | 0 | DIRECT |
| Thioredoxin-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| p53-like transcription factors | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Homeodomain-like | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| C-type lectin-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Galactose-binding domain-like | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Cystine-knot cytokines | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| FnI-like domain | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| RNA-binding domain, RBD | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| E set domains | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| (Trans)glycosidases | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| EGF/Laminin | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Voltage-gated potassium channels | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Kazal-type serine protease inhibitors | 0 | DIRECT |
| Immunoglobulin | 0.8383 | INHERITED FROM: synencephalon || olfactory bulb glomerulus || medial longitudinal fasciculus || scale || white matter || glomerular layer |
| WD40 repeat-like | 0.8383 | INHERITED FROM: sensory system || eye || retinal photoreceptor layer || photoreceptor outer segment layer || retinal outer nuclear layer |
| Fibronectin type III | 0.8888 | INHERITED FROM: synencephalon || medial longitudinal fasciculus || white matter || glomerular layer |
| Concanavalin A-like lectins/glucanases | 0.9024 | INHERITED FROM: epidermis |
| Ankyrin repeat | 0.9479 | INHERITED FROM: radial glial cell || ventricular zone || neuroblast (sensu Vertebrata) |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| "Winged helix" DNA-binding domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| DUSP-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| TIMP-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| SH3-domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| BRCT domain | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| (Phosphotyrosine protein) phosphatases II | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Nicotinic receptor ligand binding domain-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| TPR-like | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| GFP-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| GLA-domain | 0 | Direct |
| NAD(P)-binding Rossmann-fold domains | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| L domain-like | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| SRF-like | 0 | Direct |
| alpha/beta-Hydrolases | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Connexin43 | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| Ubiquitin-like | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Ras GEF | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| PLP-dependent transferases | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| PP2C-like | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| ADC-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Interleukin 8-like chemokines | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Kelch motif | 0 | Direct |
| Caspase-like | 0 | Direct |
| Lipocalins | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| 4-helical cytokines | 0 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
| POZ domain | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| LDL receptor-like module | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| UBA-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| BPTI-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| CCHHC domain | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| DNase I-like | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| PGBD-like | 0 | Direct |
| EF-hand | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| TNF-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| MFS general substrate transporter | 0 | Direct |
| Kringle-like | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| ALDH-like | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
| Cysteine proteinases | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| HAD-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| F-box domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| HCP-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| L27 domain | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| WW domain | 0 | Direct |
| GTPase activation domain, GAP | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Orange domain-like | 0 | Direct |
| beta-beta-alpha zinc fingers | 0 | Direct |
| ARM repeat | 0 | Direct |
| Thioredoxin-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| GroES-like | 0 | Direct |
| SET domain | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| p53-like transcription factors | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Histone-fold | 0 | Direct |
| DEATH domain | 0 | Direct |
| STAT | 0 | Direct |
| Homeodomain-like | 0 | Direct |
| SNARE-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Sema domain | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Insulin-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| NHL repeat | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| PX domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| vWA-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| ACT-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| C-type lectin-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Galactose-binding domain-like | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Cystine-knot cytokines | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| UBC-like | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Translational machinery components | 0 | Direct |
| FnI-like domain | 0 | Direct |
| PH domain-like | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| Cyclin-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| Translation proteins | 0 | Direct |
| Notch domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| SH2 domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| LCCL domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| RNA-binding domain, RBD | 0 | Direct |
| Polo-box domain | 0 | Direct |
| E set domains | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| HMG-box | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| CalX-like | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| (Trans)glycosidases | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| EGF/Laminin | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Voltage-gated potassium channels | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Cytokine | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| HIT-like | 0 | Direct |
| PKD domain | 0 | Direct |
| Kazal-type serine protease inhibitors | 0 | Direct |
| Immunoglobulin | 0.8383 | Inherited |
| WD40 repeat-like | 0.8383 | Inherited |
| Fibronectin type III | 0.8888 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.9024 | Inherited |
| Ankyrin repeat | 0.9479 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
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Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49785,57184 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
111418,81321 111418 - Hormone receptor domain 81321 - Family A G protein-coupled receptor-like | 0 | DIRECT |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
56112,47769 56112 - Protein kinase-like (PK-like) 47769 - SAM/Pointed domain | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
75399,75399 75399 - Plakin repeat 75399 - Plakin repeat | 0 | DIRECT |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | DIRECT |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC) | 0 | DIRECT |
82153,82153 82153 - FAS1 domain 82153 - FAS1 domain | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | DIRECT |
69179,69179 69179 - Integrin domains 69179 - Integrin domains | 0 | DIRECT |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | DIRECT |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | DIRECT |
52799,49562 52799 - (Phosphotyrosine protein) phosphatases II 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
54001,143791 54001 - Cysteine proteinases 143791 - DUSP-like | 0 | DIRECT |
90193,90193 90193 - Notch domain 90193 - Notch domain | 0 | DIRECT |
46966,47473 46966 - Spectrin repeat 47473 - EF-hand | 0 | DIRECT |
57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like | 0 | DIRECT |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55021,56534 55021 - ACT-like 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0 | DIRECT |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
55550,55550 55550 - SH2 domain 55550 - SH2 domain | 0 | DIRECT |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0 | DIRECT |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
51412,51412 51412 - Inosine monophosphate dehydrogenase (IMPDH) 51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | DIRECT |
57196,90193 57196 - EGF/Laminin 90193 - Notch domain | 0 | DIRECT |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0 | DIRECT |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | DIRECT |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | DIRECT |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56112,56112 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | DIRECT |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin | 0 | DIRECT |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0 | DIRECT |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
47655,49417 47655 - STAT 49417 - p53-like transcription factors | 0 | DIRECT |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0 | DIRECT |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
55166,51294 55166 - Hedgehog/DD-peptidase 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
49785,49899 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | DIRECT |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | DIRECT |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | DIRECT |
49562,48350 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48350 - GTPase activation domain, GAP | 0 | DIRECT |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
57603,57603 57603 - FnI-like domain 57603 - FnI-like domain | 0 | DIRECT |
82109,100909 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | DIRECT |
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT | 0 | DIRECT |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | DIRECT |
103575,48726 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | DIRECT |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | DIRECT |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | DIRECT |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53300,53300 53300 - vWA-like 53300 - vWA-like | 0 | DIRECT |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | DIRECT |
57184,57603 57184 - Growth factor receptor domain 57603 - FnI-like domain | 0 | DIRECT |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
82199,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
103575,81296 103575 - Plexin repeat 81296 - E set domains | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
48452,81901 48452 - TPR-like 81901 - HCP-like | 0 | DIRECT |
82109,82109 82109 - MIR domain 82109 - MIR domain | 0 | DIRECT |
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains | 0 | DIRECT |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
49758,47473 49758 - Calpain large subunit, middle domain (domain III) 47473 - EF-hand | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 0 | DIRECT |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | DIRECT |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | DIRECT |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | DIRECT |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
101288,50156 101288 - L27 domain 50156 - PDZ domain-like | 0 | DIRECT |
49265,49899 49265 - Fibronectin type III 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | DIRECT |
100909,49899 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like | 0 | DIRECT |
49417,47719 49417 - p53-like transcription factors 47719 - p53 tetramerization domain | 0 | DIRECT |
47454,57959 47454 - A DNA-binding domain in eukaryotic transcription factors 57959 - Leucine zipper domain | 0 | DIRECT |
49854,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48097,56112 48097 - Regulator of G-protein signaling, RGS 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | DIRECT |
52058,49265 52058 - L domain-like 49265 - Fibronectin type III | 0 | DIRECT |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
141072,141072 141072 - CalX-like 141072 - CalX-like | 0 | DIRECT |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49785,49785 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | DIRECT |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | DIRECT |
50729,50729 50729 - PH domain-like 50729 - PH domain-like | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
50729,50044 50729 - PH domain-like 50044 - SH3-domain | 0 | DIRECT |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | DIRECT |
90257,57997 90257 - Myosin rod fragments 57997 - Tropomyosin | 0 | DIRECT |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | DIRECT |
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels | 0 | DIRECT |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | DIRECT |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | DIRECT |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
49854,57196 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin | 0 | DIRECT |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | DIRECT |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9024 | INHERITED FROM: synencephalon || medial longitudinal fasciculus || white matter |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9855 | INHERITED FROM: synencephalon || brain nucleus || brainstem || medial longitudinal fasciculus || white matter |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | Direct |
49785,57184 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | Direct |
111418,81321 111418 - Hormone receptor domain 81321 - Family A G protein-coupled receptor-like | 0 | Direct |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
56112,47769 56112 - Protein kinase-like (PK-like) 47769 - SAM/Pointed domain | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
75399,75399 75399 - Plakin repeat 75399 - Plakin repeat | 0 | Direct |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | Direct |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC) | 0 | Direct |
82153,82153 82153 - FAS1 domain 82153 - FAS1 domain | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | Direct |
69179,69179 69179 - Integrin domains 69179 - Integrin domains | 0 | Direct |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | Direct |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | Direct |
52799,49562 52799 - (Phosphotyrosine protein) phosphatases II 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
54001,143791 54001 - Cysteine proteinases 143791 - DUSP-like | 0 | Direct |
90193,90193 90193 - Notch domain 90193 - Notch domain | 0 | Direct |
46966,47473 46966 - Spectrin repeat 47473 - EF-hand | 0 | Direct |
57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like | 0 | Direct |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | Direct |
55021,56534 55021 - ACT-like 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0 | Direct |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
55550,55550 55550 - SH2 domain 55550 - SH2 domain | 0 | Direct |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0 | Direct |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
51412,51412 51412 - Inosine monophosphate dehydrogenase (IMPDH) 51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | Direct |
57196,90193 57196 - EGF/Laminin 90193 - Notch domain | 0 | Direct |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0 | Direct |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | Direct |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | Direct |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56112,56112 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | Direct |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin | 0 | Direct |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0 | Direct |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
47655,49417 47655 - STAT 49417 - p53-like transcription factors | 0 | Direct |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0 | Direct |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
55166,51294 55166 - Hedgehog/DD-peptidase 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
49785,49899 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | Direct |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | Direct |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | Direct |
49562,48350 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48350 - GTPase activation domain, GAP | 0 | Direct |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
57603,57603 57603 - FnI-like domain 57603 - FnI-like domain | 0 | Direct |
82109,100909 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | Direct |
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT | 0 | Direct |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | Direct |
103575,48726 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | Direct |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | Direct |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | Direct |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | Direct |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | Direct |
53300,53300 53300 - vWA-like 53300 - vWA-like | 0 | Direct |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | Direct |
57184,57603 57184 - Growth factor receptor domain 57603 - FnI-like domain | 0 | Direct |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
82199,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
103575,81296 103575 - Plexin repeat 81296 - E set domains | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
48452,81901 48452 - TPR-like 81901 - HCP-like | 0 | Direct |
82109,82109 82109 - MIR domain 82109 - MIR domain | 0 | Direct |
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains | 0 | Direct |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | Direct |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
49758,47473 49758 - Calpain large subunit, middle domain (domain III) 47473 - EF-hand | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 0 | Direct |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | Direct |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | Direct |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | Direct |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
101288,50156 101288 - L27 domain 50156 - PDZ domain-like | 0 | Direct |
49265,49899 49265 - Fibronectin type III 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | Direct |
100909,49899 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like | 0 | Direct |
49417,47719 49417 - p53-like transcription factors 47719 - p53 tetramerization domain | 0 | Direct |
47454,57959 47454 - A DNA-binding domain in eukaryotic transcription factors 57959 - Leucine zipper domain | 0 | Direct |
49854,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48097,56112 48097 - Regulator of G-protein signaling, RGS 56112 - Protein kinase-like (PK-like) | 0 | Direct |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | Direct |
52058,49265 52058 - L domain-like 49265 - Fibronectin type III | 0 | Direct |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
141072,141072 141072 - CalX-like 141072 - CalX-like | 0 | Direct |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49785,49785 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | Direct |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | Direct |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | Direct |
50729,50729 50729 - PH domain-like 50729 - PH domain-like | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
50729,50044 50729 - PH domain-like 50044 - SH3-domain | 0 | Direct |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | Direct |
90257,57997 90257 - Myosin rod fragments 57997 - Tropomyosin | 0 | Direct |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | Direct |
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels | 0 | Direct |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | Direct |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | Direct |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
49854,57196 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin | 0 | Direct |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | Direct |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9024 | Inherited |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9855 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
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Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49899,57196,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
82109,82109,100909 82109 - MIR domain 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
101912,103575,48726 101912 - Sema domain 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | DIRECT |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
75399,75399,75399 75399 - Plakin repeat 75399 - Plakin repeat 75399 - Plakin repeat | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57196,57196,90193 57196 - EGF/Laminin 57196 - EGF/Laminin 90193 - Notch domain | 0 | DIRECT |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | DIRECT |
49854,57196,49854 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
57603,57603,57603 57603 - FnI-like domain 57603 - FnI-like domain 57603 - FnI-like domain | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
69179,69179,69179 69179 - Integrin domains 69179 - Integrin domains 69179 - Integrin domains | 0 | DIRECT |
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | DIRECT |
57184,52058,49265 57184 - Growth factor receptor domain 52058 - L domain-like 49265 - Fibronectin type III | 0 | DIRECT |
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0 | DIRECT |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
82109,100909,49899 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57184,57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
48726,49265,49265 48726 - Immunoglobulin 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
52058,49265,49265 52058 - L domain-like 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
57196,63825,57196 57196 - EGF/Laminin 63825 - YWTD domain 57196 - EGF/Laminin | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
57184,57184,57196 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
57196,90193,90193 57196 - EGF/Laminin 90193 - Notch domain 90193 - Notch domain | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
46966,46966,47473 46966 - Spectrin repeat 46966 - Spectrin repeat 47473 - EF-hand | 0 | DIRECT |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
103575,81296,81296 103575 - Plexin repeat 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors | 0 | DIRECT |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
82199,57667,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
52743,49785,57184 52743 - Subtilisin-like 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
49854,49785,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
50156,50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
90193,90193,90193 90193 - Notch domain 90193 - Notch domain 90193 - Notch domain | 0 | DIRECT |
49265,49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
47459,55785,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | DIRECT |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
49785,49785,49899 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47031,50729,50729 47031 - Second domain of FERM 50729 - PH domain-like 50729 - PH domain-like | 0 | DIRECT |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9297 | INHERITED FROM: synencephalon || medial longitudinal fasciculus || white matter |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9977 | INHERITED FROM: synencephalon || skeletal muscle cell || brain nucleus || brainstem || medial longitudinal fasciculus || white matter |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49899,57196,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
82109,82109,100909 82109 - MIR domain 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
101912,103575,48726 101912 - Sema domain 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | Direct |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
75399,75399,75399 75399 - Plakin repeat 75399 - Plakin repeat 75399 - Plakin repeat | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57196,57196,90193 57196 - EGF/Laminin 57196 - EGF/Laminin 90193 - Notch domain | 0 | Direct |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | Direct |
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | Direct |
49854,57196,49854 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | Direct |
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
57603,57603,57603 57603 - FnI-like domain 57603 - FnI-like domain 57603 - FnI-like domain | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
69179,69179,69179 69179 - Integrin domains 69179 - Integrin domains 69179 - Integrin domains | 0 | Direct |
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | Direct |
57184,52058,49265 57184 - Growth factor receptor domain 52058 - L domain-like 49265 - Fibronectin type III | 0 | Direct |
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | Direct |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0 | Direct |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
82109,100909,49899 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57184,57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
48726,49265,49265 48726 - Immunoglobulin 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
52058,49265,49265 52058 - L domain-like 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
57196,63825,57196 57196 - EGF/Laminin 63825 - YWTD domain 57196 - EGF/Laminin | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
57184,57184,57196 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
57196,90193,90193 57196 - EGF/Laminin 90193 - Notch domain 90193 - Notch domain | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
46966,46966,47473 46966 - Spectrin repeat 46966 - Spectrin repeat 47473 - EF-hand | 0 | Direct |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
103575,81296,81296 103575 - Plexin repeat 81296 - E set domains 81296 - E set domains | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors | 0 | Direct |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
82199,57667,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
52743,49785,57184 52743 - Subtilisin-like 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | Direct |
49854,49785,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | Direct |
50156,50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
90193,90193,90193 90193 - Notch domain 90193 - Notch domain 90193 - Notch domain | 0 | Direct |
49265,49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
47459,55785,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | Direct |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
49785,49785,49899 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47031,50729,50729 47031 - Second domain of FERM 50729 - PH domain-like 50729 - PH domain-like | 0 | Direct |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9297 | Inherited |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9977 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this ZA term
 |
Plot tree as:
| |
Download Newick format tree:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this ZA term
 |
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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