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CTD Chemicals (CC): Hydrocarbons, Aromatic 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DNA-glycosylase | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Lipoxigenase | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Probable bacterial effector-binding domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Saposin | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| STAT | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Virus ectodomain | 0 | DIRECT |
| Hermes dimerisation domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| GDNF receptor-like | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| TSP-1 type 1 repeat | 0.0008405 | DIRECT |
| Growth factor receptor domain | 0.002614 | INHERITED FROM: Curcumin || Chloromercuribenzoates || napabucasin || Benzamides || Triclosan || Diarylheptanoids |
| NAD(P)-binding Rossmann-fold domains | 0.005085 | INHERITED FROM: 9,10-phenanthrenequinone || 2,6-dibromophenol || 3,3',4,4',5,5'-hexabromobiphenyl || Benzophenones || Pentachlorophenol || 2,4-dibromophenol || Fenofibrate || DEET || K 7174 || 2-bromophenol || 1,2-naphthoquinone || 3,3',4,4'-tetrabromobiphenyl || 2,2',3,4',5',6-hexachlorobiphenyl || methyl salicylate || 2,6-dichloro-4-nitrophenol |
| PLP-dependent transferases | 0.01392 | INHERITED FROM: K 7174 |
| (Phosphotyrosine protein) phosphatases II | 0.02199 | INHERITED FROM: 2-(oxalylamino)benzoic acid || Benzo(a)pyrene || ortho-Aminobenzoates || nitrophenylphosphate || Aminobenzoates || Sertraline |
| Leucine zipper domain | 0.02318 | INHERITED FROM: Terphenyl Compounds || Hydroxybenzoates || Fibric Acids || Chloromercuribenzoates || Styrene || Benzophenones || 1-Naphthylamine || Anthracenes || Chlorobenzenes || Benzylidene Compounds || Benzoates || 1-nitropyrene || Dinitrobenzenes || 1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one || Catechols || Sulindac || Mercuribenzoates || Biphenyl Compounds || Nitrobenzenes || Chlorodiphenyl (54% Chlorine) || NSC668394 || Stilbenes || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Benzenesulfonates || Lignans || Naphthalenes || nectandrin-B || Diarylheptanoids || Chlorobenzoates || Sertraline |
| PH domain-like | 0.03523 | INHERITED FROM: Daunorubicin || Pyrenes || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Polycyclic Aromatic Hydrocarbons |
| Calponin-homology domain, CH-domain | 0.03758 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || Polycyclic Aromatic Hydrocarbons |
| FnI-like domain | 0.04074 | INHERITED FROM: Lovastatin || Simvastatin || Phenylurea Compounds || Stilbenes |
| GTPase activation domain, GAP | 0.05177 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Polycyclic Aromatic Hydrocarbons |
| Interleukin 8-like chemokines | 0.05254 | INHERITED FROM: Oxytetracycline || 3,4,5,3',4'-pentachlorobiphenyl || Hydroxybenzoates || acteoside || butenafine || Styrene || roflumilast N-oxide || hydroxyhydroquinone || Terbinafine || Minocycline || sirtinol || Chlorobenzenes || Zearalenone || catechol || Toluene 2,4-Diisocyanate || Benzylidene Compounds || 1-nitropyrene || Tosyllysine Chloromethyl Ketone || Telmisartan || Halogenated Diphenyl Ethers || Simvastatin || Isoproterenol || Dibenzocycloheptenes || Dinitrobenzenes || meclocycline || Catechols || 3-nitrofluoranthene || Hydrolyzable Tannins || Styrenes || Polychlorinated Biphenyls || Chlorophenols || Biphenyl Compounds || Nitrobenzenes || Catecholamines || Imatinib Mesylate || Roflumilast || fexofenadine || beta-hydroxy simvastatin acid || polydatin || Benzocycloheptenes || 3-aminofluoranthene || Benzylamines || Tetracyclines || Chrysenes || BIRB 796 || Morphinans || Fluorenes || 3-chlorophenol || Polyphenols || Terfenadine || Morphine Derivatives |
| Mitochondrial carrier | 0.07125 | INHERITED FROM: Abietanes || dehydroabietylamine |
| HMG-box | 0.07789 | INHERITED FROM: Lignans || Polyphenols |
| Histone-fold | 0.08028 | INHERITED FROM: decabromobiphenyl ether || Naphthoquinones || Benzhydryl Compounds || 2,3-bis(3'-hydroxybenzyl)butyrolactone || bisphenol A |
| SNARE fusion complex | 0.08104 | INHERITED FROM: Heroin || Morphinans || Morphine Derivatives |
| RNA-binding domain, RBD | 0.08701 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || Dihydroxydihydrobenzopyrenes || 2,3,5-(triglutathion-S-yl)hydroquinone || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Second domain of FERM | 0.1002 | INHERITED FROM: Pyrenes || Benzopyrenes |
| Cysteine-rich domain | 0.1079 | INHERITED FROM: puag-haad || 2,2',4,4',5-brominated diphenyl ether || Emodin |
| Integrin alpha N-terminal domain | 0.113 | INHERITED FROM: Tetracycline || napabucasin || Tetracyclines |
| Hemopexin-like domain | 0.113 | INHERITED FROM: pyrazolanthrone || demethoxycurcumin || Tyrphostins || Anthracenes || Lovastatin || Silybin || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Benzylidene Compounds || Simvastatin || bis(4-hydroxycinnamoyl)methane || Catechols || Doxycycline || Chloramphenicol || Nitrobenzenes || Phloroglucinol || Tetracyclines || Benzenesulfonates || Flavonolignans || Diarylheptanoids || hydroquinone |
| BRCT domain | 0.113 | INHERITED FROM: Pyrogallol || Benzyl Compounds || Daunorubicin || Anthracyclines || riccardin D || myristicin || Etoposide |
| Periplasmic binding protein-like II | 0.1258 | INHERITED FROM: Dizocilpine Maleate || Dibenzocycloheptenes || Benzocycloheptenes |
| Rhodanese/Cell cycle control phosphatase | 0.1258 | INHERITED FROM: 1-Naphthylamine || 2-(2-hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone || riccardin D || pifithrin || Naphthalenes || Sertraline |
| GroES-like | 0.1403 | INHERITED FROM: Naphthols || Benzophenones || Pentachlorophenol || Fenofibrate || Chlorobenzenes || Benz(a)Anthracenes || Chlorophenols || walrycin A |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.1403 | INHERITED FROM: VER-246608 || tamibarotene || riccardin D || Catechols || Dopamine |
| Frizzled cysteine-rich domain | 0.1561 | INHERITED FROM: tetrachlorodian |
| PGBD-like | 0.1733 | INHERITED FROM: Fibric Acids || pyrazolanthrone || Tyrphostins || 3,3',4,5'-tetrahydroxystilbene || Benzophenones || Fenofibrate || Benzene || Anthracenes || Lovastatin || Silybin || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Benzylidene Compounds || Simvastatin || bis(4-hydroxycinnamoyl)methane || Catechols || Doxycycline || Chloramphenicol || Phenylurea Compounds || Nitrobenzenes || Phloroglucinol || Tetracyclines || Benzenesulfonates || RTKI cpd || Flavonolignans || Diarylheptanoids || hydroquinone |
| SMAD/FHA domain | 0.1782 | INHERITED FROM: Pyrogallol || sirtinol || Benzopyrenes || Aristolochic Acids |
| Periplasmic binding protein-like I | 0.2339 | INHERITED FROM: Dizocilpine Maleate || Dibenzocycloheptenes || lactisole |
| A DNA-binding domain in eukaryotic transcription factors | 0.2363 | INHERITED FROM: 4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol || Hydroxybenzoates || 4-(E)-((p-tolylimino)-methylbenzene-1,2-diol) || Chloromercuribenzoates || 1-Naphthylamine || Chlorobenzenes || Benzoates || Vitamin K 3 || Dinitrobenzenes || Catechols || Nitrobenzenes || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Vitamin K || Dinitrochlorobenzene || Diarylheptanoids || Sertraline |
| Nucleic acid-binding proteins | 0.2598 | INHERITED FROM: riccardin D || Anisoles || Lignans |
| Caspase-like | 0.2623 | INHERITED FROM: Pyrogallol || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Donepezil || Hydroxybenzoates || fosbretabulin || Morphine || Stilbestrols || Benzyl Compounds || pyrazolanthrone || 5-OH-BDE-47 || NSC 680410 || Phenanthrenes || 3-bromoacetylamino benzoic acid ethyl ester || 4-(3,5-dimethoxystyryl)phenyl acetate || Parabens || Cresols || 1-Naphthylamine || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Anacardic Acids || 10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone || Polybrominated Biphenyls || Toluene || Thymol || WP 631 || Anthracenes || Lovastatin || Remoxipride || Humic Substances || Loratadine || catechol || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || Epirubicin || NCX 4040 || Benzylidene Compounds || 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea || BDMC-A || Bromobenzoates || 1,4-anthraquinone || Indenes || Halogenated Diphenyl Ethers || gingerol || Isoproterenol || NCQ 344 || dehydroxymethylepoxyquinomicin || Dibenzocycloheptenes || Propranolol || Hydroquinones || Capsaicin || Sorafenib || ABT-737 || propylparaben || Anthraquinones || Catechols || Sulindac || 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane || Phenylurea Compounds || pifithrin || honokiol || Aminobenzoates || Resveratrol || Biphenyl Compounds || sesamol || Allylbenzene Derivatives || Nitrobenzenes || FLLL 32 || Catecholamines || Imatinib Mesylate || suillin || Win 55212-2 || Benzocycloheptenes || Stilbenes || Cyproheptadine || Fenamates || Tosyl Compounds || 2,4,3',5'-tetramethoxystilbene || Benzenesulfonates || bakuchiol || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || Lignans || Flavonolignans || Polyphenols || sulindac sulfide || Phenol || Naphthalenes || Boc-D-FMK || Nitrophenols || Diarylheptanoids || Masoprocol || Terfenadine || Sertraline || Morphine Derivatives |
| Serpins | 0.2699 | INHERITED FROM: 2,3-dimethoxy-1,4-naphthoquinone |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2809 | INHERITED FROM: Naphthols || Terphenyl Compounds || entacapone || Phloretin || Fibric Acids || Morphine || 1,2,5,8-tetrahydroxy anthraquinone || 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene || Vanillic Acid || 2,6-dihydroxyanthraquinone || 3-hydroxydesloratadine || Phenanthrenes || 1-hydroxypyrene || alizarin || dibenzo(a,l)pyrene || ortho-Aminobenzoates || shikonin || Carbanilides || 4-nitrophenol || Flurbiprofen || Thymol || Anthracenes || 1,4-dihydroxyanthraquinone || Zearalenone || plumbagin || Loratadine || Silybin || Hydroxyestrones || glabridin || 1-naphthol || Polychloroterphenyl Compounds || Benz(a)Anthracenes || pterostilbene || triclocarban || Naproxen || Dibenzocycloheptenes || Anthraquinones || Catechols || Salicylic Acid || Aminobenzoates || Naphthaleneacetic Acids || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || Diflunisal || Hydroxybenzoate Ethers || Methylcholanthrene || Estrogens, Catechol || Chlorodiphenyl (54% Chlorine) || anthrarobin || methyl salicylate || Phloroglucinol || Benzocycloheptenes || Cyproheptadine || Fenamates || Aroclors || Flavonolignans || Morphinans || 4-hydroxyestrone || sulindac sulfone || alloin || Anthralin || Clofibric Acid || Nitrophenols || Masoprocol || Morphine Derivatives |
| Bcl-2 inhibitors of programmed cell death | 0.29 | INHERITED FROM: 2,2-bis(4-glycidyloxyphenyl)propane || AH 23848 || bicalutamide || naphtho(1,2-b)furan-4,5-dione || Hydroxybenzoates || Morphine || 9,10-anthraquinone || Iodobenzoates || Benzyl Compounds || Plicamycin || pyrazolanthrone || Tyrphostins || Phenanthrenes || 3,4,5,4'-tetramethoxystilbene || Parabens || gyrophoric acid || Aspirin || Fenofibrate || 1-Naphthylamine || 2-(2-hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone || ortho-Aminobenzoates || 2,4,5,2',4',5'-hexachlorobiphenyl || Polybrominated Biphenyls || Toluene || Anthracenes || atranorin || Silybin || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || Benzylidene Compounds || benzo(a)pyrene diolepoxide I || pterostilbene || Indenes || Halogenated Diphenyl Ethers || Isoproterenol || 2,2',4,4'-tetrabromodiphenyl ether || Capsaicin || Sorafenib || danthron || ABT-737 || propylparaben || Anthraquinones || Tetrahydronaphthalenes || tetracycline CMT-3 || Catechols || Sulindac || Phenylurea Compounds || Hydrolyzable Tannins || Aminobenzoates || Resveratrol || Styrenes || Biphenyl Compounds || N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate || Allylbenzene Derivatives || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || Catecholamines || Imatinib Mesylate || Triiodobenzoic Acids || 6-OH-BDE-47 || Safrole || salvin || Stilbenes || Tetracyclines || Fenamates || Toluidines || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || 1'-acetoxychavicol acetate || acetochlor || Flavonolignans || BP-1-102 || Morphinans || Etoposide || Fluorenes || Polyphenols || 3,4,5,4'-tetrahydroxystilbene || Nitrophenols || Diarylheptanoids || Benzyl Alcohols || Morphine Derivatives |
| TNF receptor-like | 0.3121 | INHERITED FROM: Hydroxybenzoates || Fibric Acids || Stilbestrols || 5-OH-BDE-47 || 3,4,5,4'-tetramethoxystilbene || Benzophenones || Parabens || Fenofibrate || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Polybrominated Biphenyls || Benzylidene Compounds || aloe emodin || 2,2',4,4'-tetrabromodiphenyl ether || Catechols || Biphenyl Compounds || Stilbenes || butylphen || Polyphenols || Diarylheptanoids |
| Protein kinase-like (PK-like) | 0.3198 | INHERITED FROM: ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate || Hydroxybenzoates || tylophorine || N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide || 5-OH-BDE-47 || puag-haad || 5-7-oxo-zeaenol || NSC 680410 || 2-aminodiphenyl || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || chrysophanic acid || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Benzylidene Compounds || tamibarotene || anethole || 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione || Indenes || AG-012986 || vaticanol C || Capsaicin || labedipinedilol A || Sorafenib || Pyrenes || afimoxifene || Catechols || Phenylurea Compounds || napabucasin || pifithrin || Polychlorinated Biphenyls || Biphenyl Compounds || Imatinib Mesylate || Win 55212-2 || liposomal doxorubicin || Triiodobenzoic Acids || Benzocycloheptenes || 6,7-dimethoxy-3-phenylquinoxaline || Stilbenes || Polycyclic Aromatic Hydrocarbons || Hexachlorobenzene || picropodophyllin || Polyphenols || Naphthalenes || Diarylheptanoids |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.3211 | INHERITED FROM: GW 7647 |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.3409 | INHERITED FROM: AGN 193109 || EPI 001 || Carbaryl || pyrene || isobutylparaben || 2,2-bis(4-glycidyloxyphenyl)propane || Dihydrostilbenoids || homosalate || benzylparaben || 3-phenoxybenzoic acid || ethyl-p-hydroxybenzoate || Hexestrol || Tritolyl Phosphates || 2,4,6-trichlorophenyl-4'-aminophenyl ether || Gemfibrozil || 4-nonylphenol || nonylphenol || Benzophenones || 2,2',4,4'-tetrahydroxybenzophenone || phantolid || 4-tert-octylphenol || Dicofol || pentabrominated diphenyl ether 100 || 2-tert-butylphenol || Resorcinols || Bibenzyls || Cresols || isobutyl-4-hydroxybenzoate || chlormethoxynil || 1,1-bis(4-hydroxyphenyl)cyclohexane || 2,4,6-trichlorophenyl 4-nitrophenyl ether || bisphenol B || phenanthrene || Bezafibrate || Anthracenes || Chlorobenzenes || Zearalenone || Butylated Hydroxyanisole || Silybin || Epirubicin || tetralin || Benzoates || 2-phenylphenol || tetrachlorodian || Clomiphene || 4-ethylphenol || triclocarban || Indenes || Clofibrate || 4-cumylphenol || tribromodiphenyl ether 28 || aroclor 1260 || 2,2',4,4',5-brominated diphenyl ether || 3,4,3',4'-tetrachloroazobenzene || Bexarotene || dioxybenzone || Permethrin || Trityl Compounds || 4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid || p-tert-amylphenol || pencycuron || 4-phenylphenol || 3,5-di-tert-butyl-4-hydroxybenzaldehyde || SR 11237 || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || Idarubicin || 2,2',3,5',6-pentachlorobiphenyl || Chlorophenols || 2,2-di(4-methacryloxyphenyl)propane || 4,4'-hexafluorisopropylidene diphenol || 2,6-diisopropylnaphthalene || bifenox || Stilbenes || oxybenzone || 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane || nitrofen || Ro 41-5253 || pirarubicin || 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene || 3-benzylidene camphor || bakuchiol || Toluidines || fenpyroximate || butylphen || 2,4,5,2',5'-pentachlorobiphenyl || acetyl methyl tetramethyl tetralin || hexabrominated diphenyl ether 153 || sulindac sulfone || Toremifene || Naphthalenes || 4,4'-bisphenol F || Aclarubicin || Phenolphthaleins || versalide || Diarylheptanoids || 4-octylphenol || Chlorobenzoates |
| Leukotriene A4 hydrolase N-terminal domain | 0.3536 | INHERITED FROM: 2-Naphthylamine |
| GroEL-intermediate domain like | 0.3536 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.3905 | INHERITED FROM: Masoprocol |
| Kazal-type serine protease inhibitors | 0.3926 | INHERITED FROM: Fluorobenzenes || Sulfobromophthalein || Rosuvastatin Calcium || Phenolphthaleins |
| MFS general substrate transporter | 0.4123 | INHERITED FROM: 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Hippurates || Phloretin || Amitriptyline || Diphenhydramine || 7-(deoxyadenosin-N(6)-yl)aristolactam I || 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid || Fluorobenzenes || Sulfobromophthalein || Rosuvastatin Calcium || Sulpiride || Norepinephrine || Naproxen || Propranolol || Bumetanide || p-Aminohippuric Acid || Salicylic Acid || Aminobenzoates || Naphthaleneacetic Acids || 2,2',4,4',5,6'-hexabromodiphenyl ether || Aminohippuric Acids || Fenamates || Phenolphthaleins |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4301 | INHERITED FROM: Chloromercuribenzoates || Isoproterenol || Dinitrobenzenes || Catechols || Biphenyl Compounds || Nitrobenzenes || Catecholamines || 6-OH-BDE-47 || Naphthalenes |
| Six-hairpin glycosidases | 0.4301 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
| Glycerol-3-phosphate (1)-acyltransferase | 0.4502 | INHERITED FROM: GW 7647 |
| SNF-like | 0.4502 | INHERITED FROM: Indans || Norepinephrine || Dopamine || 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || indatraline |
| ARM repeat | 0.4604 | INHERITED FROM: Dihydroxydihydrobenzopyrenes || 2,3,5-(triglutathion-S-yl)hydroquinone |
| SCOP hierarchy in SUPERFAMILY | 0.4658 | INHERITED FROM: Hydroquinones || Benzhydryl Compounds || bisphenol F |
| alpha/beta-Hydrolases | 0.4698 | INHERITED FROM: 6-O-monoacetylmorphine || bis(4-nitrophenyl)phosphate || Heroin || Bisphenol A-Glycidyl Methacrylate || Nitrophenols || Morphine Derivatives |
| E2F-DP heterodimerization region | 0.4734 | INHERITED FROM: 5-OH-BDE-47 || 6-OH-BDE-47 || UF010 compound |
| Kringle-like | 0.504 | INHERITED FROM: N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Hydroxybenzoates || demethoxycurcumin || Aspirin || Humic Substances || Silybin || anethole || Norepinephrine || Simvastatin || gingerol || Isoproterenol || bis(4-hydroxycinnamoyl)methane || Propranolol || alpha-benzoylamino-1,4-naphthoquinone || Benzenesulfonates || Flavonolignans |
| AN1-like Zinc finger | 0.5214 | INHERITED FROM: Anisoles |
| Cytokine | 0.5397 | INHERITED FROM: Phloretin || 3,4,5,3',4'-pentachlorobiphenyl || Suramin || Trinitrobenzenes || Anthracenes || 1-nitropyrene || Isoproterenol || Phloroglucinol || Naphthalenesulfonates |
| DNA/RNA polymerases | 0.5518 | INHERITED FROM: Phenalenes || Benz(a)Anthracenes || Perylene |
| Actin-like ATPase domain | 0.5598 | INHERITED FROM: Catecholamines || 6-OH-BDE-47 |
| Prefoldin | 0.5617 | INHERITED FROM: Bexarotene || ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid |
| P-loop containing nucleoside triphosphate hydrolases | 0.5885 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || riccardin D || 1-hydroxymethylpyrene || 2,3-bis(3'-hydroxybenzyl)butyrolactone |
| EGF/Laminin | 0.6005 | INHERITED FROM: Benzoates || Benzamides || benzo(e)pyrene || Triclosan |
| Ubiquitin-like | 0.6071 | INHERITED FROM: Benzopyrenes |
| GLA-domain | 0.6283 | INHERITED FROM: Tamoxifen |
| Polo-box domain | 0.6296 | INHERITED FROM: Curcumin || Benzyl Compounds || Dihydroxydihydrobenzopyrenes || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Catechols || Lignans || Diarylheptanoids |
| Smc hinge domain | 0.6296 | INHERITED FROM: 2,3-bis(3'-hydroxybenzyl)butyrolactone |
| "Winged helix" DNA-binding domain | 0.6364 | INHERITED FROM: UF010 compound |
| Concanavalin A-like lectins/glucanases | 0.6611 | INHERITED FROM: Triclosan |
| DBL homology domain (DH-domain) | 0.6698 | INHERITED FROM: benzo(e)pyrene |
| PDZ domain-like | 0.6985 | INHERITED FROM: Polycyclic Aromatic Hydrocarbons || benzo(e)pyrene |
| Cytochrome P450 | 0.7025 | INHERITED FROM: N,N-didesmethyl-4-hydroxytamoxifen || isoproturon || Pyrogallol || 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid || 2,6-dibromophenol || S-sulindac || Carbaryl || Naphthols || Terphenyl Compounds || pyrene || 4-hydroxy-N-desmethyltamoxifen || Indans || pinostilbene || 3,4,5,3',4'-pentachlorobiphenyl || 4-bromo-2-chlorophenol || Meclizine || Fibric Acids || diphenyl || Benzyl Compounds || 3,3',4,4',5,5'-hexabromobiphenyl || 2-(4-chloro-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene || pentachlorobenzene || 1-phenylazo-2-naphthol || puag-haad || benzo(c)phenanthrene || dihydrocapsaicin || Gemfibrozil || 1,4-naphthoquinone || estragole || 3,4,5,3',4',5'-hexachlorobiphenyl || elemicin || Styrene || Phenanthrenes || 3,3',4,5'-tetrahydroxystilbene || Benzophenones || 1-chloropyrene || alizarin || 2,4-dibromophenol || hexafluoron || 2,3,3',4,4',5-hexachlorobiphenyl || 4-tert-octylphenol || droloxifene || 1,3-dinitropyrene || 2,2',4,6'-tetramethoxystilbene || Linuron || 6-methylchrysene || 6-chrysenamine || Cresols || 1-Naphthylamine || chrysophanic acid || shikonin || Orphenadrine || Carbanilides || Toluene || 2,6-dimethylnaphthalene || Dextrorphan || chlorfluazuron || 2-nitrofluoranthene || Xylenes || phenanthrene || physcione || Bezafibrate || Anthracenes || fimasartan || DEET || 3-methylchrysene || Chlorobenzenes || Loratadine || Silybin || indeno(1,2,3-cd)pyrene || dimethocaine || 4-biphenylamine || 3,6-dinitrobenzopyrene || 1-naphthol || Polychloroterphenyl Compounds || Phenalenes || Benz(a)Anthracenes || dibenzoanthracene-3,4-dihydrodiol || benzotriphenylene || pentabromophenol || 4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide || Indenes || 2-bromophenol || 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide || tribromodiphenyl ether 28 || Dibenzocycloheptenes || Propranolol || 6-nitrobenzo(a)pyrene || teriflunomide || 4-dichlorobenzene || N-desmethyltamoxifen || 2-nitroanisole || 2-Naphthylamine || naphtho(2,3-a)pyrene || Permethrin || 4-(methylsulfinyl)phenol || 3,3',4,4'-tetrabromobiphenyl || Phenylurea Compounds || zafirlukast || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || GW 3965 || Aminobenzoates || Styrenes || Polychlorinated Biphenyls || naphthalene || purpurin || Acenaphthenes || KN 93 || styrofoam || Chlorophenols || Biphenyl Compounds || 4,4'-cyclohexylidenebisphenol || 4,4'-hexafluorisopropylidene diphenol || Allylbenzene Derivatives || dimethoxycurcumin || epsilon-viniferin || Nitrobenzenes || triptolide || 6-nitrochrysene || UAB 30 || 1,2,4-trichlorobenzene || Chlorodiphenyl (54% Chlorine) || 9,10-Dimethyl-1,2-benzanthracene || cumene hydroperoxide || dimemorfan || 9-phenanthrol || 2,2',3,4',5',6-hexachlorobiphenyl || trans-1,2-dihydro-1,2-naphthalenediol || Phloroglucinol || Dextromethorphan || Benzocycloheptenes || Stilbenes || 2,4,6-tribromophenol || Benzylamines || Fenamates || 2-dichlorobenzene || hyperforin || 2,4,3',5'-tetramethoxystilbene || Toluidines || benzo(a)pyrene 7,8-dihydrodiol || 4-isopropylphenol || 2,4,5,2',5'-pentachlorobiphenyl || 5-methylchrysene || Emodin || Aroclors || triflumuron || Morphinans || Fluorenes || Naphthalenes || 4,4'-bisphenol F || 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || 5,12-naphthacenequinone || 4-methylchrysene || Nitrophenols || walrycin A || Diarylheptanoids || Sertraline |
| Chaperone J-domain | 0.7056 | INHERITED FROM: Carbaryl |
| Tropomyosin | 0.7206 | INHERITED FROM: Mitoxantrone |
| FAD/NAD(P)-binding domain | 0.7253 | INHERITED FROM: juglone || Nitrobenzoates |
| UBC-like | 0.749 | INHERITED FROM: K 7174 || Anisoles |
| Cystine-knot cytokines | 0.7591 | INHERITED FROM: N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Plicamycin || Phenanthrenes || Chlorobenzenes || Zearalenone || Benzylidene Compounds || Simvastatin || Nitrobenzenes || MOPP protocol || Procarbazine || Stilbenes || Tetracyclines || aristolochic acid I |
| Bromodomain | 0.7898 | INHERITED FROM: 4,4'-hexafluorisopropylidene diphenol |
| Flavoproteins | 0.7924 | INHERITED FROM: Hydroxybenzoates || Fibric Acids || Phenanthrenes || Benzophenones || Aspirin || ortho-Aminobenzoates || Toluene || Salicylates || pterostilbene || Simvastatin || Capsaicin || Aminobenzoates || Polychlorinated Biphenyls || Biphenyl Compounds || Indophenol || Phloroglucinol || Fenamates || Benzoic Acid || Fluorenes |
| p53-like transcription factors | 0.7956 | INHERITED FROM: benzo(a)pyrene-3,6-quinone || Morphine || Iodobenzoates || 2-Acetylaminofluorene || 1-Naphthylamine || benzo(a)pyrene-1,6-quinone || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Anacardic Acids || Benzene || Chlorobenzenes || Iopamidol || Norepinephrine || Simvastatin || Catechols || Resveratrol || Acenaphthenes || Nitrobenzenes || Indophenol || Imatinib Mesylate || Triiodobenzoic Acids || Stilbenes || WP 744 || Benzenesulfonates || 1'-acetoxychavicol acetate || Polyphenols || Diarylheptanoids || Benzyl Alcohols || Terfenadine |
| Acetyl-CoA synthetase-like | 0.8066 | INHERITED FROM: Benzophenones || Phenylurea Compounds || GW 7647 |
| GST C-terminal domain-like | 0.8143 | INHERITED FROM: dibenzo(a,l)pyrene || ortho-Aminobenzoates || 2-allylphenol || Chlorobenzenes || Cysteinyldopa || Dinitrobenzenes || Dihydroxyphenylalanine || Aminobenzoates || isomethyleugenol || Nitrobenzenes || cumene hydroperoxide || Fenamates || 4-propylphenol || Naphthalenesulfonates || Dinitrochlorobenzene |
| PYP-like sensor domain (PAS domain) | 0.8524 | INHERITED FROM: Hydroxybenzoates || butamben || 3,3',4,5'-tetrahydroxystilbene || Benzoates || Benzocaine || Pyrenes || Catechols || Aminobenzoates || Benzopyrenes || Polychlorinated Biphenyls || 4,4'-hexafluorisopropylidene diphenol || Catecholamines || Fluorenes || Polyphenols || Diarylheptanoids |
| E set domains | 0.8606 | INHERITED FROM: Tosyllysine Chloromethyl Ketone || Naphthalenes |
| Nucleotidylyl transferase | 0.8724 | INHERITED FROM: Benzophenones || 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || Fenofibrate |
| CCCH zinc finger | 0.8853 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
| ABC transporter transmembrane region | 0.8853 | INHERITED FROM: 4'-methoxy-1-naphthylfenoterol || Zeranol || 2-Acetylaminofluorene || Cresols || tetrabromobisphenol A || Bezafibrate || Loratadine || Epirubicin || Dibenzocycloheptenes || Pravastatin || Catechols || Phenylurea Compounds || zafirlukast || Metaproterenol || Catecholamines || Imatinib Mesylate || fexofenadine || Benzocycloheptenes || Cyproheptadine || zearalenol || Flavonolignans || Fluorenes || Terfenadine |
| Toll/Interleukin receptor TIR domain | 0.9124 | INHERITED FROM: 9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || bis(4-hydroxycinnamoyl)methane || Diarylheptanoids |
| DEATH domain | 0.9215 | INHERITED FROM: N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Hydroxybenzoates || tylophorine || fosbretabulin || Stilbestrols || Benzyl Compounds || 5-OH-BDE-47 || Phenanthrenes || 3,4,5,4'-tetramethoxystilbene || Parabens || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Anacardic Acids || Polybrominated Biphenyls || Toluene || Anthracenes || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || Benzylidene Compounds || Halogenated Diphenyl Ethers || dehydroxymethylepoxyquinomicin || aloe emodin || Capsaicin || Sorafenib || propylparaben || Anthraquinones || Catechols || Sulindac || Polychlorinated Biphenyls || Biphenyl Compounds || Allylbenzene Derivatives || Nitrobenzenes || Imatinib Mesylate || suillin || Win 55212-2 || Stilbenes || bakuchiol || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || butylphen || 1'-acetoxychavicol acetate || Polyphenols || Phenol || Aclarubicin || Diarylheptanoids || Benzyl Alcohols || Terfenadine |
| MHC antigen-recognition domain | 0.9263 | INHERITED FROM: Minocycline || tamibarotene || Tetrahydronaphthalenes || Tetracyclines || entinostat || Naphthalenes |
| Lipocalins | 0.9263 | INHERITED FROM: 1-anilino-8-naphthalenesulfonate || 11-(dansylamino)undecanoic acid || Bezafibrate || Dansyl Compounds || Naphthalenesulfonates || Anilino Naphthalenesulfonates |
| ClpP/crotonase | 0.9332 | INHERITED FROM: GW 7647 |
| Tubulin nucleotide-binding domain-like | 0.934 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || dibenzo(a,l)pyrene || resorcinol || 2,4,3',5'-tetramethoxystilbene |
| Fibronectin type III | 0.9405 | INHERITED FROM: 2-(oxalylamino)benzoic acid || Pyrenes || Benzamides || benzo(e)pyrene || Triclosan |
| Tubulin C-terminal domain-like | 0.9519 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || dibenzo(a,l)pyrene || resorcinol || 2,4,3',5'-tetramethoxystilbene |
| Hairpin loop containing domain-like | 0.9535 | INHERITED FROM: Tamoxifen |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.9538 | INHERITED FROM: N-(4-O-glycerol-3-methoxybenzyl)nonivamide || Capsaicin || Hydroxydopamines || Phloroglucinol || Polyphenols |
| Riboflavin synthase domain-like | 0.9538 | INHERITED FROM: N-(4-O-glycerol-3-methoxybenzyl)nonivamide || Capsaicin || Hydroxydopamines || Phloroglucinol || Polyphenols |
| Thioredoxin-like | 0.9699 | INHERITED FROM: dichlone || dinocap || dibenzo(a,l)pyrene || ortho-Aminobenzoates || 2-allylphenol || Chlorobenzenes || Cysteinyldopa || 2,2',4,4',5-brominated diphenyl ether || Dihydroxyphenylalanine || Anisoles || isomethyleugenol || Nitrobenzenes || cumene hydroperoxide || Fenamates || 4-propylphenol |
| Voltage-gated potassium channels | 0.9795 | INHERITED FROM: Flufenamic Acid || Mibefradil || Niflumic Acid || Mexiletine |
| Cadherin-like | 0.9847 | INHERITED FROM: dibenzo(a,l)pyrene || Triclosan |
| SH2 domain | 0.9889 | INHERITED FROM: naphtho(1,2-b)furan-4,5-dione || benzo(a)pyrene-3,6-quinone || benzo(a)pyrene-1,6-quinone || Benzylidene Compounds || tamibarotene || Simvastatin || honokiol || Imatinib Mesylate || WP1066 || Polyphenols || Naphthalenes |
| Single hybrid motif | 0.9948 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Metalloproteases ("zincins"), catalytic domain | 1 | INHERITED FROM: PD 0325901 || pyrazolanthrone || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Doxycycline || Chloramphenicol || Tetracyclines || RTKI cpd |
| Ribosomal protein S5 domain 2-like | 1 | INHERITED FROM: riccardin D |
| FYVE/PHD zinc finger | 1 | INHERITED FROM: 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Cyclin-like | 1 | INHERITED FROM: N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || bicalutamide || Hydroxybenzoates || acteoside || tylophorine || 5-OH-BDE-47 || Parabens || Polybrominated Biphenyls || Silybin || Indenes || gingerol || riccardin D || labedipinedilol A || Sulindac || aspidin BB || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || AGN 194204 || LG 100268 || Stilbenes || Ro 41-5253 || UF010 compound || 3,5,3',4',5'-pentamethoxystilbene |
| SH3-domain | 1 | INHERITED FROM: Benzo(a)pyrene || honokiol || Benzopyrenes || 2,3',4,4',5-pentachlorobiphenyl |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: resorcinol |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: resorcinol |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | INHERITED FROM: Pyrenes |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | INHERITED FROM: 2,5,2',5'-tetrachlorobiphenyl || 4-nonylphenol || 2,4,2',4'-tetrachlorobiphenyl || tetrabromobisphenol A || Polybrominated Biphenyls || Toluene || 2,4,4'-trichlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || benzamide || 2,2',3,5',6-pentachlorobiphenyl || Propofol || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || 4-octylphenol |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: Fibric Acids || butamben || 3,3',4,5'-tetrahydroxystilbene || Clofibrate || Benzocaine || Polychlorinated Biphenyls || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: 2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone || Epinephrine || 8-Hydroxy-2-(di-n-propylamino)tetralin || Norepinephrine || 1-(8-bromobenzo(1,2-b;4,5-b')difuran-4-yl)-2-aminopropane |
| Nicotinic receptor ligand binding domain-like | 1 | INHERITED FROM: 2,5,2',5'-tetrachlorobiphenyl || 4-nonylphenol || 2,4,2',4'-tetrachlorobiphenyl || tetrabromobisphenol A || Polybrominated Biphenyls || Toluene || 2,4,4'-trichlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || benzamide || 2,2',3,5',6-pentachlorobiphenyl || Propofol || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || 4-octylphenol |
| TNF-like | 1 | INHERITED FROM: diphenyliodonium || Diphenhydramine || Plicamycin || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Bezafibrate || Lovastatin || aloe emodin || peroben || Biphenyl Compounds || Indophenol |
| 4-helical cytokines | 1 | INHERITED FROM: 2,2',3',4,4',5-hexachlorobiphenyl || Sodium Salicylate || Phloretin || FK 706 || Hydroxybenzoates || 2-tert-butylhydroquinone || 4-nonylphenol || Tyrphostins || Trinitrobenzenes || FEC protocol || Phenanthrenes || Benzene || Anthracenes || Lovastatin || Epirubicin || Benzylidene Compounds || Simvastatin || Dibenzocycloheptenes || Catechols || Aminobenzoates || Polychlorinated Biphenyls || Biphenyl Compounds || Catecholamines || Phloroglucinol || Benzocycloheptenes || Stilbenes || Ro 41-5253 || Propofol || Flavonolignans || Morphinans || Polyphenols || Diarylheptanoids || Terfenadine |
| Intermediate filament protein, coiled coil region | 1 | INHERITED FROM: Hydroquinones || ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid |
| Immunoglobulin | 1 | INHERITED FROM: HX 630 || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Triclosan |
| Homeodomain-like | 1 | INHERITED FROM: Triclosan |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DNA-glycosylase | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| BolA-like | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| SIS domain | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| DUSP-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| ARID-like | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| FF domain | 0 | Direct |
| N-(deoxy)ribosyltransferase-like | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Lipoxigenase | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| AXH domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PUG domain-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| AhpD-like | 0 | Direct |
| LanC-like | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| BRK domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| MIT domain | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| ISP domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Nop domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Metallothionein | 0 | Direct |
| Stathmin | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| PEBP-like | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| DNA clamp | 0 | Direct |
| Release factor | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| SRF-like | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| ITPase-like | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| AlbA-like | 0 | Direct |
| R3H domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| BSD domain-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Proteasome activator | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Aldolase | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| BEACH domain | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| PKD domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| KA1-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PWI domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Probable bacterial effector-binding domain | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| LEM domain | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| GFP-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| RGC domain-like | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Pentein | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| CalX-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Saposin | 0 | Direct |
| DLC | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| STAT | 0 | Direct |
| ALDH-like | 0 | Direct |
| Connexin43 | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| TIMP-like | 0 | Direct |
| PRTase-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Integrin domains | 0 | Direct |
| Annexin | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Mss4-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Virus ectodomain | 0 | Direct |
| Hermes dimerisation domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Notch domain | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Tim10-like | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| WW domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| PapD-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| GDNF receptor-like | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| TSP-1 type 1 repeat | 0.0008405 | Direct |
| Growth factor receptor domain | 0.002614 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.005085 | Inherited |
| PLP-dependent transferases | 0.01392 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.02199 | Inherited |
| Leucine zipper domain | 0.02318 | Inherited |
| PH domain-like | 0.03523 | Inherited |
| Calponin-homology domain, CH-domain | 0.03758 | Inherited |
| FnI-like domain | 0.04074 | Inherited |
| GTPase activation domain, GAP | 0.05177 | Inherited |
| Interleukin 8-like chemokines | 0.05254 | Inherited |
| Mitochondrial carrier | 0.07125 | Inherited |
| HMG-box | 0.07789 | Inherited |
| Histone-fold | 0.08028 | Inherited |
| SNARE fusion complex | 0.08104 | Inherited |
| RNA-binding domain, RBD | 0.08701 | Inherited |
| Second domain of FERM | 0.1002 | Inherited |
| Cysteine-rich domain | 0.1079 | Inherited |
| Integrin alpha N-terminal domain | 0.113 | Inherited |
| Hemopexin-like domain | 0.113 | Inherited |
| BRCT domain | 0.113 | Inherited |
| Periplasmic binding protein-like II | 0.1258 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.1258 | Inherited |
| GroES-like | 0.1403 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.1403 | Inherited |
| Frizzled cysteine-rich domain | 0.1561 | Inherited |
| PGBD-like | 0.1733 | Inherited |
| SMAD/FHA domain | 0.1782 | Inherited |
| Periplasmic binding protein-like I | 0.2339 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.2363 | Inherited |
| Nucleic acid-binding proteins | 0.2598 | Inherited |
| Caspase-like | 0.2623 | Inherited |
| Serpins | 0.2699 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2809 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.29 | Inherited |
| TNF receptor-like | 0.3121 | Inherited |
| Protein kinase-like (PK-like) | 0.3198 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.3211 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.3409 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.3536 | Inherited |
| GroEL-intermediate domain like | 0.3536 | Inherited |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.3905 | Inherited |
| Kazal-type serine protease inhibitors | 0.3926 | Inherited |
| MFS general substrate transporter | 0.4123 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4301 | Inherited |
| Six-hairpin glycosidases | 0.4301 | Inherited |
| Glycerol-3-phosphate (1)-acyltransferase | 0.4502 | Inherited |
| SNF-like | 0.4502 | Inherited |
| ARM repeat | 0.4604 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 0.4658 | Inherited |
| alpha/beta-Hydrolases | 0.4698 | Inherited |
| E2F-DP heterodimerization region | 0.4734 | Inherited |
| Kringle-like | 0.504 | Inherited |
| AN1-like Zinc finger | 0.5214 | Inherited |
| Cytokine | 0.5397 | Inherited |
| DNA/RNA polymerases | 0.5518 | Inherited |
| Actin-like ATPase domain | 0.5598 | Inherited |
| Prefoldin | 0.5617 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.5885 | Inherited |
| EGF/Laminin | 0.6005 | Inherited |
| Ubiquitin-like | 0.6071 | Inherited |
| GLA-domain | 0.6283 | Inherited |
| Polo-box domain | 0.6296 | Inherited |
| Smc hinge domain | 0.6296 | Inherited |
| "Winged helix" DNA-binding domain | 0.6364 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.6611 | Inherited |
| DBL homology domain (DH-domain) | 0.6698 | Inherited |
| PDZ domain-like | 0.6985 | Inherited |
| Cytochrome P450 | 0.7025 | Inherited |
| Chaperone J-domain | 0.7056 | Inherited |
| Tropomyosin | 0.7206 | Inherited |
| FAD/NAD(P)-binding domain | 0.7253 | Inherited |
| UBC-like | 0.749 | Inherited |
| Cystine-knot cytokines | 0.7591 | Inherited |
| Bromodomain | 0.7898 | Inherited |
| Flavoproteins | 0.7924 | Inherited |
| p53-like transcription factors | 0.7956 | Inherited |
| Acetyl-CoA synthetase-like | 0.8066 | Inherited |
| GST C-terminal domain-like | 0.8143 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.8524 | Inherited |
| E set domains | 0.8606 | Inherited |
| Nucleotidylyl transferase | 0.8724 | Inherited |
| CCCH zinc finger | 0.8853 | Inherited |
| ABC transporter transmembrane region | 0.8853 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.9124 | Inherited |
| DEATH domain | 0.9215 | Inherited |
| MHC antigen-recognition domain | 0.9263 | Inherited |
| Lipocalins | 0.9263 | Inherited |
| ClpP/crotonase | 0.9332 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.934 | Inherited |
| Fibronectin type III | 0.9405 | Inherited |
| Tubulin C-terminal domain-like | 0.9519 | Inherited |
| Hairpin loop containing domain-like | 0.9535 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.9538 | Inherited |
| Riboflavin synthase domain-like | 0.9538 | Inherited |
| Thioredoxin-like | 0.9699 | Inherited |
| Voltage-gated potassium channels | 0.9795 | Inherited |
| Cadherin-like | 0.9847 | Inherited |
| SH2 domain | 0.9889 | Inherited |
| Single hybrid motif | 0.9948 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 1 | Inherited |
| Ribosomal protein S5 domain 2-like | 1 | Inherited |
| FYVE/PHD zinc finger | 1 | Inherited |
| Cyclin-like | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Nicotinic receptor ligand binding domain-like | 1 | Inherited |
| TNF-like | 1 | Inherited |
| 4-helical cytokines | 1 | Inherited |
| Intermediate filament protein, coiled coil region | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| beta-CASP RNA-metabolising hydrolases | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| GDNF receptor-like | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| Co-chaperone p23-like | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Pentapeptide repeats | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Ricin B-like | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| TRASH domain | 0 | DIRECT |
| Ornithine decarboxylase antizyme-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Putative glucosidase YicI, domain 3 | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Alkaline phosphatase | 0 | DIRECT |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| eIF5a N-terminal domain-like | 0 | DIRECT |
| A20-like zinc finger | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Synatpobrevin N-terminal domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| Bacterial PLC | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Complement components | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| DEATH effector domain, DED | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Hermes transposase-like | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| GAF domain | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Prokaryotic proteases | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Nuclear receptor | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| TatD Mg-dependent DNase-like | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| Platelet-derived growth factor-like | 0 | DIRECT |
| Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| PUG domain | 0 | DIRECT |
| FolH catalytic domain-like | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| SelR domain | 0 | DIRECT |
| Interferon regulatory factor | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Virus ectodomain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Ribosomal proteins L24p and L21e | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| CalX-beta domain | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Crisp domain | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Starch-binding domain | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| p53 DNA-binding domain-like | 0 | DIRECT |
| Glycosyl hydrolases family 35 catalytic domain | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| Cysteine rich domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| IMD domain | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Sedlin (SEDL) | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Short-chain cytokines | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| Osteonectin | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| HtrA-like serine proteases | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| HkH motif-containing C2H2 finger | 0 | DIRECT |
| Diacylglycerol kinase-like | 0 | DIRECT |
| GAT domain | 0 | DIRECT |
| Aldo-keto reductases (NADP) | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Colipase-binding domain | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| CPH domain | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| YicI N-terminal domain-like | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Retinoblastoma tumor suppressor domains | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| GDI-like N domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Animal lipoxigenases | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Glycerol-3-phosphate transporter | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Oligosaccharide phosphorylase | 0 | DIRECT |
| Arylamine N-methyltransferase | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Link domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Pseudouridine synthase II TruB | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| PNP-oxidase like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Ccg1/TafII250-interacting factor B (Cib) | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| PCI domain (PINT motif) | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| Variant SAM domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| NKL-like | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| 5' nucleotidase-like | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | DIRECT |
| Integrin beta EGF-like domains | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| gamma-adaptin C-terminal appendage domain-like | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| Exostosin | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Interleukin-1 (IL-1) | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| STAT DNA-binding domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| MBT repeat | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| RGC domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Splicing factor U2AF subunits | 0 | DIRECT |
| Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Ecto-ART | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0.0006587 | DIRECT |
| Tandem AAA-ATPase domain | 0.01271 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Tyrosine-dependent oxidoreductases | 0.01648 | INHERITED FROM: 9,10-phenanthrenequinone || 2,6-dibromophenol || 3,3',4,4',5,5'-hexabromobiphenyl || 2,4-dibromophenol || DEET || 2-bromophenol || 1,2-naphthoquinone || 3,3',4,4'-tetrabromobiphenyl || 2,2',3,4',5',6-hexachlorobiphenyl || 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane || 2,4,5,2',5'-pentachlorobiphenyl |
| Leucine zipper domain | 0.01966 | INHERITED FROM: Terphenyl Compounds || Hydroxybenzoates || Fibric Acids || Chloromercuribenzoates || Styrene || Benzophenones || 1-Naphthylamine || Anthracenes || Chlorobenzenes || Benzoates || 1-nitropyrene || Dinitrobenzenes || 1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one || Catechols || Sulindac || Mercuribenzoates || Biphenyl Compounds || Nitrobenzenes || Chlorodiphenyl (54% Chlorine) || NSC668394 || Stilbenes || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Benzenesulfonates || Naphthalenes || nectandrin-B || Diarylheptanoids || Chlorobenzoates || Sertraline |
| Growth factor receptor domain | 0.02453 | INHERITED FROM: Curcumin || Chloromercuribenzoates || Tetracycline || Benzamides || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Triclosan || Lignans || Diarylheptanoids |
| Calponin-homology domain, CH-domain | 0.03234 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || Polycyclic Aromatic Hydrocarbons |
| Interleukin 8-like chemokines | 0.04573 | INHERITED FROM: Oxytetracycline || 3,4,5,3',4'-pentachlorobiphenyl || Hydroxybenzoates || acteoside || butenafine || Styrene || roflumilast N-oxide || hydroxyhydroquinone || Terbinafine || Minocycline || sirtinol || Chlorobenzenes || Zearalenone || catechol || Toluene 2,4-Diisocyanate || Benzylidene Compounds || 1-nitropyrene || Tosyllysine Chloromethyl Ketone || Telmisartan || Halogenated Diphenyl Ethers || Simvastatin || Isoproterenol || Dibenzocycloheptenes || Dinitrobenzenes || meclocycline || 3-nitrofluoranthene || Hydrolyzable Tannins || Styrenes || Polychlorinated Biphenyls || Chlorophenols || Biphenyl Compounds || Nitrobenzenes || Catecholamines || Imatinib Mesylate || Roflumilast || fexofenadine || beta-hydroxy simvastatin acid || polydatin || Benzocycloheptenes || 3-aminofluoranthene || Benzylamines || Tetracyclines || Chrysenes || BIRB 796 || Morphinans || Fluorenes || 3-chlorophenol || Polyphenols || Terfenadine || Morphine Derivatives |
| PLC-like (P variant) | 0.05056 | INHERITED FROM: puag-haad |
| DEATH domain, DD | 0.05628 | INHERITED FROM: Hydroxybenzoates || Parabens || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Anthracenes || Halogenated Diphenyl Ethers || Anthraquinones || Catechols || Biphenyl Compounds || Stilbenes || 1'-acetoxychavicol acetate || Polyphenols || Phenol || Diarylheptanoids || hydroquinone |
| Glutathione S-transferase (GST), C-terminal domain | 0.05628 | INHERITED FROM: dibenzo(a,l)pyrene || ortho-Aminobenzoates || 2-allylphenol || Chlorobenzenes || Cysteinyldopa || Dinitrobenzenes || Dihydroxyphenylalanine || Aminobenzoates || isomethyleugenol || Nitrobenzenes || cumene hydroperoxide || Fenamates || 4-propylphenol || Naphthalenesulfonates || Dinitrochlorobenzene |
| Mitochondrial carrier | 0.06804 | INHERITED FROM: dehydroabietylamine |
| HMG-box | 0.06804 | INHERITED FROM: Polyphenols |
| SNARE fusion complex | 0.07087 | INHERITED FROM: Heroin || Morphinans || Morphine Derivatives |
| First domain of FERM | 0.07949 | INHERITED FROM: Benzopyrenes |
| Motor proteins | 0.08047 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || Pyrenes || Benzopyrenes |
| Canonical RBD | 0.09508 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || Dihydroxydihydrobenzopyrenes || 2,3,5-(triglutathion-S-yl)hydroquinone || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Hemopexin-like domain | 0.09961 | INHERITED FROM: pyrazolanthrone || demethoxycurcumin || Tyrphostins || Anthracenes || Lovastatin || Silybin || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Benzylidene Compounds || Simvastatin || bis(4-hydroxycinnamoyl)methane || Catechols || Doxycycline || Chloramphenicol || Nitrobenzenes || Phloroglucinol || Tetracyclines || Benzenesulfonates || Flavonolignans || Diarylheptanoids || hydroquinone |
| Glutathione S-transferase (GST), N-terminal domain | 0.09961 | INHERITED FROM: ortho-Aminobenzoates || Mefenamic Acid || Chlorobenzenes || Dinitrobenzenes || Nitrobenzenes || cumene hydroperoxide || Fenamates || Dinitrochlorobenzene |
| Matrix metalloproteases, catalytic domain | 0.09961 | INHERITED FROM: pyrazolanthrone || demethoxycurcumin || Tyrphostins || Fenofibrate || Anthracenes || Lovastatin || Silybin || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Benzylidene Compounds || Simvastatin || bis(4-hydroxycinnamoyl)methane || Catechols || Doxycycline || Chloramphenicol || Nitrobenzenes || Phloroglucinol || Tetracyclines || Benzenesulfonates || RTKI cpd || Flavonolignans || Diarylheptanoids || hydroquinone |
| Third domain of FERM | 0.09975 | INHERITED FROM: Doxorubicin || Daunorubicin || Anthracyclines || Benzopyrenes |
| Second domain of FERM | 0.1043 | INHERITED FROM: Pyrenes || Benzopyrenes |
| Nucleosome core histones | 0.1057 | INHERITED FROM: decabromobiphenyl ether || Naphthoquinones || Hydroquinones || Benzhydryl Compounds || 2,3-bis(3'-hydroxybenzyl)butyrolactone || bisphenol A |
| BCR-homology GTPase activation domain (BH-domain) | 0.1214 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Frizzled cysteine-rich domain | 0.1392 | INHERITED FROM: tetrachlorodian |
| UDPGT-like | 0.1392 | INHERITED FROM: Naphthols || Terphenyl Compounds || entacapone || Phloretin || Hydroxybenzoates || 2-tert-butylhydroquinone || Fibric Acids || Morphine || Benzyl Compounds || 1,2,5,8-tetrahydroxy anthraquinone || 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene || Vanillic Acid || 2,6-dihydroxyanthraquinone || 3-hydroxydesloratadine || Phenanthrenes || 1-hydroxypyrene || alizarin || dibenzo(a,l)pyrene || Resorcinols || ortho-Aminobenzoates || shikonin || Carbanilides || 4-nitrophenol || Flurbiprofen || Thymol || Anthracenes || 1,4-dihydroxyanthraquinone || Zearalenone || plumbagin || Loratadine || Silybin || Hydroxyestrones || glabridin || 1-naphthol || Polychloroterphenyl Compounds || Benz(a)Anthracenes || pterostilbene || triclocarban || Indenes || Naproxen || Dibenzocycloheptenes || Anthraquinones || Catechols || Sulindac || Phenylurea Compounds || Salicylic Acid || Aminobenzoates || Naphthaleneacetic Acids || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || Diflunisal || Hydroxybenzoate Ethers || Methylcholanthrene || Estrogens, Catechol || Chlorodiphenyl (54% Chlorine) || anthrarobin || methyl salicylate || Phloroglucinol || Benzocycloheptenes || Cyproheptadine || Fenamates || Emodin || Lignans || Aroclors || Flavonolignans || Morphinans || 4-hydroxyestrone || sulindac sulfone || Naphthalenes || alloin || Anthralin || Clofibric Acid || Nitrophenols || Diarylheptanoids || Masoprocol || Morphine Derivatives |
| MMP N-terminal domain | 0.1549 | INHERITED FROM: Fibric Acids || pyrazolanthrone || demethoxycurcumin || Tyrphostins || 3,3',4,5'-tetrahydroxystilbene || Benzophenones || Fenofibrate || Benzene || Anthracenes || Lovastatin || Silybin || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Benzylidene Compounds || Simvastatin || bis(4-hydroxycinnamoyl)methane || Catechols || Doxycycline || Chloramphenicol || Phenylurea Compounds || Nitrobenzenes || Phloroglucinol || Tetracyclines || Benzenesulfonates || RTKI cpd || Flavonolignans || Diarylheptanoids || hydroquinone |
| Phosphate binding protein-like | 0.1549 | INHERITED FROM: Dizocilpine Maleate || Dibenzocycloheptenes || Benzocycloheptenes |
| Caspase recruitment domain, CARD | 0.1549 | INHERITED FROM: Terphenyl Compounds || pyrazolanthrone || 5-OH-BDE-47 || Parabens || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || Halogenated Diphenyl Ethers || Capsaicin || propylparaben || Catechols || Resveratrol || Polychlorinated Biphenyls || Biphenyl Compounds || Chlorodiphenyl (54% Chlorine) || Flavonolignans || Diarylheptanoids |
| G proteins | 0.1617 | INHERITED FROM: Lovastatin |
| Double-stranded RNA-binding domain (dsRBD) | 0.1729 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Protein kinases, catalytic subunit | 0.2042 | INHERITED FROM: ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate || Hydroxybenzoates || Iodobenzoates || 4-vinyl-2,6-dimethoxyphenol || puag-haad || 5-7-oxo-zeaenol || NSC 680410 || 2-aminodiphenyl || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || chrysophanic acid || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Benzylidene Compounds || tamibarotene || anethole || Indenes || AG-012986 || vaticanol C || labedipinedilol A || Sorafenib || afimoxifene || Catechols || Phenylurea Compounds || napabucasin || pifithrin || Benzopyrenes || Polychlorinated Biphenyls || Biphenyl Compounds || Imatinib Mesylate || Win 55212-2 || liposomal doxorubicin || Triiodobenzoic Acids || Benzocycloheptenes || 6,7-dimethoxy-3-phenylquinoxaline || Stilbenes || Polycyclic Aromatic Hydrocarbons || Hexachlorobenzene || picropodophyllin || Polyphenols || Naphthalenes || Diarylheptanoids |
| A DNA-binding domain in eukaryotic transcription factors | 0.2142 | INHERITED FROM: 4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol || Hydroxybenzoates || 4-(E)-((p-tolylimino)-methylbenzene-1,2-diol) || Chloromercuribenzoates || 1-Naphthylamine || Chlorobenzenes || Benzoates || Vitamin K 3 || Dinitrobenzenes || Catechols || Nitrobenzenes || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Vitamin K || Dinitrochlorobenzene || Diarylheptanoids || Sertraline |
| Pleckstrin-homology domain (PH domain) | 0.2417 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.2566 | INHERITED FROM: puag-haad || 2,2',4,4',5-brominated diphenyl ether |
| Serpins | 0.2636 | INHERITED FROM: 2,3-dimethoxy-1,4-naphthoquinone |
| Acetylcholinesterase-like | 0.2648 | INHERITED FROM: 6-O-monoacetylmorphine || Indans || Phenanthrenes || Heroin || Aminobenzoates || Bisphenol A-Glycidyl Methacrylate || Morphinans || Nitrophenols || Morphine Derivatives |
| Ephrin receptor ligand binding domain | 0.2648 | INHERITED FROM: 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide |
| Bcl-2 inhibitors of programmed cell death | 0.2648 | INHERITED FROM: 2,2-bis(4-glycidyloxyphenyl)propane || AH 23848 || bicalutamide || naphtho(1,2-b)furan-4,5-dione || Hydroxybenzoates || Morphine || 9,10-anthraquinone || Iodobenzoates || Benzyl Compounds || Plicamycin || pyrazolanthrone || Tyrphostins || Phenanthrenes || 3,4,5,4'-tetramethoxystilbene || Parabens || gyrophoric acid || Aspirin || Fenofibrate || 1-Naphthylamine || 2-(2-hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone || ortho-Aminobenzoates || 2,4,5,2',4',5'-hexachlorobiphenyl || Polybrominated Biphenyls || Toluene || Anthracenes || atranorin || Silybin || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || shogaol || Benzylidene Compounds || benzo(a)pyrene diolepoxide I || pterostilbene || Indenes || Halogenated Diphenyl Ethers || gingerol || Isoproterenol || 2,2',4,4'-tetrabromodiphenyl ether || Capsaicin || Sorafenib || danthron || ABT-737 || propylparaben || Anthraquinones || Tetrahydronaphthalenes || tetracycline CMT-3 || Catechols || Sulindac || Phenylurea Compounds || Hydrolyzable Tannins || Aminobenzoates || Resveratrol || Styrenes || Biphenyl Compounds || N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate || Allylbenzene Derivatives || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || Catecholamines || Imatinib Mesylate || Triiodobenzoic Acids || 6-OH-BDE-47 || Safrole || salvin || Stilbenes || Tetracyclines || Fenamates || Toluidines || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || 1'-acetoxychavicol acetate || acetochlor || Flavonolignans || BP-1-102 || Morphinans || Etoposide || Fluorenes || Polyphenols || 3,4,5,4'-tetrahydroxystilbene || Nitrophenols || Diarylheptanoids || Benzyl Alcohols || Morphine Derivatives |
| Dual specificity phosphatase-like | 0.2727 | INHERITED FROM: 1-Naphthylamine || Sertraline |
| Caspase catalytic domain | 0.294 | INHERITED FROM: Pyrogallol || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Donepezil || Hydroxybenzoates || fosbretabulin || Morphine || Stilbestrols || Benzyl Compounds || pyrazolanthrone || 5-OH-BDE-47 || NSC 680410 || Phenanthrenes || 3,3',4,5'-tetrahydroxystilbene || 3,4,5,4'-tetramethoxystilbene || 4-(3,5-dimethoxystyryl)phenyl acetate || Parabens || Cresols || 1-Naphthylamine || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Anacardic Acids || 10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone || Polybrominated Biphenyls || Toluene || Thymol || WP 631 || Anthracenes || Lovastatin || Remoxipride || Loratadine || catechol || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || Epirubicin || NCX 4040 || Benzylidene Compounds || 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea || BDMC-A || Bromobenzoates || 1,4-anthraquinone || Indenes || Halogenated Diphenyl Ethers || gingerol || Isoproterenol || NCQ 344 || dehydroxymethylepoxyquinomicin || Dibenzocycloheptenes || Propranolol || Hydroquinones || Capsaicin || Sorafenib || ABT-737 || propylparaben || Anthraquinones || Catechols || Sulindac || 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane || Phenylurea Compounds || pifithrin || honokiol || Aminobenzoates || Resveratrol || Biphenyl Compounds || sesamol || Allylbenzene Derivatives || Nitrobenzenes || FLLL 32 || Catecholamines || Imatinib Mesylate || suillin || Win 55212-2 || Benzocycloheptenes || Stilbenes || Cyproheptadine || Fenamates || Tosyl Compounds || 2,4,3',5'-tetramethoxystilbene || Vitamin K || Benzenesulfonates || bakuchiol || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || Lignans || Flavonolignans || Niflumic Acid || Polyphenols || sulindac sulfide || Phenol || Naphthalenes || Boc-D-FMK || Nitrophenols || Diarylheptanoids || Masoprocol || Terfenadine || Sertraline || Morphine Derivatives |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.294 | INHERITED FROM: juglone || Polybrominated Biphenyls || Indenes || Dinitrobenzenes || Sulindac || Dinitrochlorobenzene |
| L-arabinose binding protein-like | 0.3029 | INHERITED FROM: lactisole |
| Single strand DNA-binding domain, SSB | 0.3254 | INHERITED FROM: riccardin D |
| Actin/HSP70 | 0.3273 | INHERITED FROM: Catechols || Nitrobenzenes || Catecholamines || 6-OH-BDE-47 |
| Cell cycle transcription factor e2f-dp | 0.3606 | INHERITED FROM: Benzyl Compounds || 5-OH-BDE-47 || Benzylidene Compounds || Resveratrol || 6-OH-BDE-47 || Stilbenes || UF010 compound || Lignans |
| Rap/Ran-GAP | 0.3606 | INHERITED FROM: Dihydroxydihydrobenzopyrenes |
| RING finger domain, C3HC4 | 0.3638 | INHERITED FROM: K 7174 || Anisoles |
| FHA domain | 0.3934 | INHERITED FROM: Pyrogallol || myristicin |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4001 | INHERITED FROM: Chloromercuribenzoates || Isoproterenol || Dinitrobenzenes || Catechols || Biphenyl Compounds || Nitrobenzenes || Catecholamines || 6-OH-BDE-47 |
| Pancreatic lipase, N-terminal domain | 0.4001 | INHERITED FROM: Fibric Acids |
| SNF-like | 0.4203 | INHERITED FROM: Indans || Norepinephrine || Dopamine || 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || indatraline |
| Leukotriene A4 hydrolase N-terminal domain | 0.4416 | INHERITED FROM: 2-Naphthylamine |
| Glutathione peroxidase-like | 0.4513 | INHERITED FROM: Chlorobenzenes || Nitrobenzenes || cumene hydroperoxide |
| AN1-like Zinc finger | 0.4897 | INHERITED FROM: Anisoles |
| EGF-type module | 0.5278 | INHERITED FROM: Tyrphostins || tetrabromobisphenol A || Benzoates || Benzamides || benzo(e)pyrene || RTKI cpd |
| Proprotein convertase P-domain | 0.5397 | INHERITED FROM: Aspirin |
| L domain | 0.5397 | INHERITED FROM: Curcumin || Stilbestrols || Benzyl Compounds || Tyrphostins || Mitoxantrone || Anthracenes || Chlorobenzenes || Podophyllotoxin || Epirubicin || Benzylidene Compounds || Indenes || Tetrahydronaphthalenes || Catechols || Sulindac || Phenylurea Compounds || Resveratrol || Stilbenes || Hexachlorobenzene || Lignans || Etoposide || Polyphenols || sulindac sulfide || Diarylheptanoids || Masoprocol |
| Lipoxigenase N-terminal domain | 0.5397 | INHERITED FROM: hydroquinone |
| Papain-like | 0.557 | INHERITED FROM: Dinitrochlorobenzene |
| GLA-domain | 0.5961 | INHERITED FROM: Tamoxifen |
| Smc hinge domain | 0.5973 | INHERITED FROM: 2,3-bis(3'-hydroxybenzyl)butyrolactone |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0.5973 | INHERITED FROM: Fibric Acids || Phenanthrenes || Aspirin || Salicylates || Capsaicin || Polychlorinated Biphenyls || Biphenyl Compounds || Phloroglucinol |
| NADPH-cytochrome p450 reductase-like | 0.5973 | INHERITED FROM: Fibric Acids || Phenanthrenes || Aspirin || Salicylates || Capsaicin || Polychlorinated Biphenyls || Biphenyl Compounds || Phloroglucinol |
| Long-chain cytokines | 0.6365 | INHERITED FROM: Hydroxybenzoates || Anthracenes || Dibenzocycloheptenes || Catechols || Aminobenzoates || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || Methylcholanthrene || Catecholamines || Benzocycloheptenes || Stilbenes |
| DBL homology domain (DH-domain) | 0.6373 | INHERITED FROM: benzo(e)pyrene |
| Chaperone J-domain | 0.674 | INHERITED FROM: Carbaryl |
| Cytochrome P450 | 0.6757 | INHERITED FROM: N,N-didesmethyl-4-hydroxytamoxifen || isoproturon || Pyrogallol || 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid || 2,6-dibromophenol || S-sulindac || Carbaryl || Naphthols || Terphenyl Compounds || pyrene || 4-hydroxy-N-desmethyltamoxifen || Indans || pinostilbene || 4-bromo-2-chlorophenol || Meclizine || Fibric Acids || diphenyl || acenaphthylene || 3,3',4,4',5,5'-hexabromobiphenyl || 2-(4-chloro-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene || pentachlorobenzene || 1-phenylazo-2-naphthol || puag-haad || benzo(c)phenanthrene || dihydrocapsaicin || Gemfibrozil || 1,4-naphthoquinone || estragole || 3,4,5,3',4',5'-hexachlorobiphenyl || elemicin || Styrene || Phenanthrenes || 3,3',4,5'-tetrahydroxystilbene || Benzophenones || 1-chloropyrene || alizarin || 2,4-dibromophenol || hexafluoron || 2,3,3',4,4',5-hexachlorobiphenyl || 4-tert-octylphenol || droloxifene || 1,3-dinitropyrene || 2,2',4,6'-tetramethoxystilbene || Linuron || 6-methylchrysene || 6-chrysenamine || Cresols || 1-Naphthylamine || chrysophanic acid || Mefenamic Acid || shikonin || Orphenadrine || Carbanilides || Toluene || 2,6-dimethylnaphthalene || Dextrorphan || chlorfluazuron || 2-nitrofluoranthene || Xylenes || phenanthrene || physcione || Bezafibrate || Anthracenes || fimasartan || DEET || 3-methylchrysene || Chlorobenzenes || Loratadine || indeno(1,2,3-cd)pyrene || dimethocaine || 4-biphenylamine || 3,6-dinitrobenzopyrene || 1-naphthol || Polychloroterphenyl Compounds || Phenalenes || Benz(a)Anthracenes || dibenzoanthracene-3,4-dihydrodiol || benzotriphenylene || pentabromophenol || 4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide || 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide || Dibenzocycloheptenes || Propranolol || 2,2',4,4',5-brominated diphenyl ether || 6-nitrobenzo(a)pyrene || teriflunomide || 4-dichlorobenzene || Anthraquinones || N-desmethyltamoxifen || 2-nitroanisole || naphtho(2,3-a)pyrene || Permethrin || 4-(methylsulfinyl)phenol || 3,3',4,4'-tetrabromobiphenyl || Phenylurea Compounds || zafirlukast || GW 3965 || Aminobenzoates || Styrenes || naphthalene || purpurin || Acenaphthenes || KN 93 || styrofoam || Chlorophenols || Biphenyl Compounds || 4,4'-cyclohexylidenebisphenol || 4,4'-hexafluorisopropylidene diphenol || Allylbenzene Derivatives || dimethoxycurcumin || epsilon-viniferin || triptolide || 6-nitrochrysene || UAB 30 || 1,2,4-trichlorobenzene || Chlorodiphenyl (54% Chlorine) || 9,10-Dimethyl-1,2-benzanthracene || cumene hydroperoxide || dimemorfan || 9-phenanthrol || 2,2',3,4',5',6-hexachlorobiphenyl || trans-1,2-dihydro-1,2-naphthalenediol || Phloroglucinol || Dextromethorphan || Benzocycloheptenes || Stilbenes || 2,4,6-tribromophenol || Benzylamines || Fenamates || 2-dichlorobenzene || hyperforin || 2,4,3',5'-tetramethoxystilbene || Toluidines || benzo(a)pyrene 7,8-dihydrodiol || 4-isopropylphenol || 2,4,5,2',5'-pentachlorobiphenyl || 5-methylchrysene || Emodin || Aroclors || triflumuron || Morphinans || Fluorenes || Phenol || Naphthalenes || 4,4'-bisphenol F || 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || 5,12-naphthacenequinone || 4-methylchrysene || Nitrophenols || walrycin A || Diarylheptanoids || Sertraline |
| Leukotriene A4 hydrolase catalytic domain | 0.6775 | INHERITED FROM: 2-Naphthylamine |
| Ran-binding domain | 0.6775 | INHERITED FROM: Methylcholanthrene |
| MATH domain | 0.6775 | INHERITED FROM: Catechols || Diarylheptanoids |
| Tropomyosin | 0.6898 | INHERITED FROM: Mitoxantrone |
| Polo-box duplicated region | 0.7295 | INHERITED FROM: Curcumin || Benzyl Compounds || Catechols || Lignans || Diarylheptanoids |
| Enolase | 0.7295 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
| Extended AAA-ATPase domain | 0.7427 | INHERITED FROM: 2,3-dimethoxy-1,4-naphthoquinone |
| Bromodomain | 0.762 | INHERITED FROM: 4,4'-hexafluorisopropylidene diphenol |
| Acetyl-CoA synthetase-like | 0.7797 | INHERITED FROM: Benzophenones || Phenylurea Compounds || GW 7647 |
| Fatty acid binding protein-like | 0.7901 | INHERITED FROM: Bezafibrate |
| Galectin (animal S-lectin) | 0.7901 | INHERITED FROM: Benz(a)Anthracenes |
| UBC-related | 0.8076 | INHERITED FROM: K 7174 |
| Fibroblast growth factors (FGF) | 0.811 | INHERITED FROM: Suramin || Naphthalenesulfonates |
| Prefoldin | 0.8235 | INHERITED FROM: sulindac sulfide |
| C1 set domains (antibody constant domain-like) | 0.8342 | INHERITED FROM: Minocycline || tamibarotene || Tetrahydronaphthalenes || Tetracyclines || entinostat || Naphthalenes |
| Ngr ectodomain-like | 0.8611 | INHERITED FROM: Triclosan |
| CCCH zinc finger | 0.8623 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
| ets domain | 0.8847 | INHERITED FROM: PD 0325901 |
| ABC transporter transmembrane region | 0.8919 | INHERITED FROM: 4'-methoxy-1-naphthylfenoterol || Benzyl Compounds || Zeranol || 2-Acetylaminofluorene || Cresols || tetrabromobisphenol A || Bezafibrate || Loratadine || Daunorubicin || Epirubicin || Benzylidene Compounds || Anthracyclines || Dibenzocycloheptenes || Pravastatin || Catechols || Phenylurea Compounds || zafirlukast || Metaproterenol || Catecholamines || Imatinib Mesylate || fexofenadine || Benzocycloheptenes || Stilbenes || Cyproheptadine || zearalenol || Flavonolignans || Etoposide || Fluorenes || Terfenadine |
| Cytochrome p450 reductase N-terminal domain-like | 0.8955 | INHERITED FROM: Fibric Acids || Phenanthrenes || Aspirin || Capsaicin || Polychlorinated Biphenyls || Biphenyl Compounds || Phloroglucinol |
| Toll/Interleukin receptor TIR domain | 0.9068 | INHERITED FROM: 9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || bis(4-hydroxycinnamoyl)methane || Dinitrobenzenes || Diarylheptanoids |
| MHC antigen-recognition domain | 0.9073 | INHERITED FROM: Minocycline || tamibarotene || Tetrahydronaphthalenes || Tetracyclines || entinostat || Naphthalenes |
| Tubulin, GTPase domain | 0.9153 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || dibenzo(a,l)pyrene || resorcinol || 2,4,3',5'-tetramethoxystilbene |
| Fibronectin type II module | 0.9173 | INHERITED FROM: 3,4,5,3',4'-pentachlorobiphenyl || Tyrphostins || Norepinephrine || gingerol || Isoproterenol || Propranolol || Catecholamines || Benzenesulfonates |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.9218 | INHERITED FROM: Fibric Acids || Benzophenones || Fenofibrate |
| Fibronectin type III | 0.9219 | INHERITED FROM: 2-(oxalylamino)benzoic acid || Pyrenes || Benzamides || benzo(e)pyrene || Triclosan |
| Tubulin, C-terminal domain | 0.9352 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || dibenzo(a,l)pyrene || resorcinol || 2,4,3',5'-tetramethoxystilbene |
| S100 proteins | 0.937 | INHERITED FROM: Norepinephrine |
| Retinol binding protein-like | 0.937 | INHERITED FROM: 1-anilino-8-naphthalenesulfonate || 11-(dansylamino)undecanoic acid || Dansyl Compounds || Naphthalenesulfonates || Anilino Naphthalenesulfonates |
| PHD domain | 0.9398 | INHERITED FROM: Dihydroxydihydrobenzopyrenes || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0.9519 | INHERITED FROM: fluoranthene || 3,3',4,5'-tetrahydroxystilbene || Isoproterenol || Polychlorinated Biphenyls || Catecholamines || Fluorenes |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0.9519 | INHERITED FROM: Curcumin || Hydroxybenzoates || Aspirin || riccardin D || butylparaben || Phenylurea Compounds || Diarylheptanoids |
| ABC transporter ATPase domain-like | 0.9625 | INHERITED FROM: Hippurates || 4'-methoxy-1-naphthylfenoterol || Benzyl Compounds || Gemfibrozil || Zeranol || 2-Acetylaminofluorene || Bezafibrate || Fluorobenzenes || Loratadine || Rosuvastatin Calcium || Dibenzocycloheptenes || Pravastatin || zafirlukast || Metaproterenol || Catecholamines || fexofenadine || Benzocycloheptenes || Cyproheptadine || zearalenol || Terfenadine |
| Penta-EF-hand proteins | 0.9668 | INHERITED FROM: Diethylstilbestrol |
| Crotonase-like | 0.9668 | INHERITED FROM: GW 7647 |
| SH2 domain | 0.9751 | INHERITED FROM: naphtho(1,2-b)furan-4,5-dione || benzo(a)pyrene-3,6-quinone || 4-(3,5-dimethoxystyryl)phenyl acetate || benzo(a)pyrene-1,6-quinone || Benzylidene Compounds || tamibarotene || honokiol || Imatinib Mesylate || WP1066 || Polyphenols || Naphthalenes |
| Biotinyl/lipoyl-carrier proteins and domains | 0.9823 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| I set domains | 0.991 | INHERITED FROM: 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Benzocycloheptenes || 4-cresol |
| TNF-like | 0.9948 | INHERITED FROM: diphenyliodonium || Diphenhydramine || Plicamycin || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Bezafibrate || Lovastatin || aloe emodin || peroben || Biphenyl Compounds || Indophenol |
| Translational machinery components | 0.9977 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| C2 set domains | 0.9977 | INHERITED FROM: 3,4,5,3',4'-pentachlorobiphenyl || Hydroxybenzoates || Phenanthrenes || Benzophenones || Aspirin || Salicylates || Indenes || Simvastatin || Sulindac |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: Fibric Acids || butamben || Clofibrate || Benzocaine || Polychlorinated Biphenyls || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid |
| SH3-domain | 1 | INHERITED FROM: Benzo(a)pyrene || honokiol || Benzopyrenes || 2,3',4,4',5-pentachlorobiphenyl |
| Cyclin | 1 | INHERITED FROM: N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || bicalutamide || Hydroxybenzoates || acteoside || tylophorine || 5-OH-BDE-47 || Parabens || Silybin || gingerol || riccardin D || labedipinedilol A || Sulindac || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || AGN 194204 || Biphenyl Compounds || LG 100268 || 3,5,3',4',5'-pentamethoxystilbene |
| Pyrin domain, PYD | 1 | INHERITED FROM: Dinitrobenzenes || Dinitrochlorobenzene |
| Rhodopsin-like | 1 | INHERITED FROM: 2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone || Epinephrine || 8-Hydroxy-2-(di-n-propylamino)tetralin || Norepinephrine || 1-(8-bromobenzo(1,2-b;4,5-b')difuran-4-yl)-2-aminopropane |
| Interferons/interleukin-10 (IL-10) | 1 | INHERITED FROM: Tyrphostins || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide |
| Homeodomain | 1 | INHERITED FROM: Chloromercuribenzoates || Mercuribenzoates || Triclosan |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: resorcinol |
| Nicotinic receptor ligand binding domain-like | 1 | INHERITED FROM: 2,5,2',5'-tetrachlorobiphenyl || 4-nonylphenol || 2,4,2',4'-tetrachlorobiphenyl || tetrabromobisphenol A || Polybrominated Biphenyls || Toluene || 2,4,4'-trichlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || benzamide || 2,2',3,5',6-pentachlorobiphenyl || Propofol || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || 4-octylphenol |
| Intermediate filament protein, coiled coil region | 1 | INHERITED FROM: Hydroquinones || ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | INHERITED FROM: 2,5,2',5'-tetrachlorobiphenyl || 4-nonylphenol || 2,4,2',4'-tetrachlorobiphenyl || tetrabromobisphenol A || Polybrominated Biphenyls || Toluene || 2,4,4'-trichlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || benzamide || 2,2',3,5',6-pentachlorobiphenyl || Propofol || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || 4-octylphenol |
| Classic zinc finger, C2H2 | 1 | INHERITED FROM: resorcinol |
| Voltage-gated potassium channels | 1 | INHERITED FROM: ortho-Aminobenzoates || Flufenamic Acid || Propranolol || Fenamates || Niflumic Acid |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| beta-CASP RNA-metabolising hydrolases | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| GDNF receptor-like | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| Co-chaperone p23-like | 0 | Direct |
| RWD domain | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Stathmin | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Pentapeptide repeats | 0 | Direct |
| Connexin43 | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| Laminin-type module | 0 | Direct |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Release factor | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Ricin B-like | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| TRASH domain | 0 | Direct |
| Ornithine decarboxylase antizyme-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Putative glucosidase YicI, domain 3 | 0 | Direct |
| BolA-like | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Alkaline phosphatase | 0 | Direct |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| eIF5a N-terminal domain-like | 0 | Direct |
| A20-like zinc finger | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Class I aldolase | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | Direct |
| AXH domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Synatpobrevin N-terminal domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| FF domain | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| LON domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| APC10-like | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| Bacterial PLC | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Ferritin | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Complement components | 0 | Direct |
| DNA ligase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| DEATH effector domain, DED | 0 | Direct |
| PWI domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Hermes transposase-like | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| MAPEG domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| WW domain | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| NagB-like | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| GAF domain | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| FCH domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| DLC | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Prokaryotic proteases | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Nuclear receptor | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| STAT | 0 | Direct |
| TatD Mg-dependent DNase-like | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| Metallothionein | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| Platelet-derived growth factor-like | 0 | Direct |
| Pseudouridine synthase RsuA/RluD | 0 | Direct |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | Direct |
| Troponin T | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| PUG domain | 0 | Direct |
| FolH catalytic domain-like | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| SelR domain | 0 | Direct |
| Interferon regulatory factor | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Virus ectodomain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Ribosomal proteins L24p and L21e | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| BTG domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| CalX-beta domain | 0 | Direct |
| HMGL-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Crisp domain | 0 | Direct |
| CCHHC domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Starch-binding domain | 0 | Direct |
| Adenain-like | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Choline kinase | 0 | Direct |
| p53 DNA-binding domain-like | 0 | Direct |
| Glycosyl hydrolases family 35 catalytic domain | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| Cysteine rich domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Transferrin | 0 | Direct |
| IMD domain | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| CAT-like | 0 | Direct |
| La domain | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Sedlin (SEDL) | 0 | Direct |
| AAT-like | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Short-chain cytokines | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Troponin I | 0 | Direct |
| YWTD domain | 0 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | Direct |
| FAS1 domain | 0 | Direct |
| NagD-like | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| Osteonectin | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| LanC-like | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| HtrA-like serine proteases | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| HkH motif-containing C2H2 finger | 0 | Direct |
| Diacylglycerol kinase-like | 0 | Direct |
| GAT domain | 0 | Direct |
| Aldo-keto reductases (NADP) | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Colipase-binding domain | 0 | Direct |
| CUE domain | 0 | Direct |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | Direct |
| B56-like | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| MSP-like | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Notch domain | 0 | Direct |
| PUA domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| CPH domain | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| YicI N-terminal domain-like | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| COMT-like | 0 | Direct |
| Retinoblastoma tumor suppressor domains | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| GDI-like N domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Animal lipoxigenases | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| VHS domain | 0 | Direct |
| Glycerol-3-phosphate transporter | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Oligosaccharide phosphorylase | 0 | Direct |
| Arylamine N-methyltransferase | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Macro domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Link domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Fumble-like | 0 | Direct |
| Pseudouridine synthase II TruB | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| PNP-oxidase like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Ccg1/TafII250-interacting factor B (Cib) | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| PCI domain (PINT motif) | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Reductases | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| Variant SAM domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Neurotrophin | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Nop domain | 0 | Direct |
| ARID domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| BSD domain | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| WGR domain | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| LeuD-like | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| PDEase | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| UBX domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Thiolase-related | 0 | Direct |
| NKL-like | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| SRF-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| SAND domain | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| 5' nucleotidase-like | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | Direct |
| Integrin beta EGF-like domains | 0 | Direct |
| PKD domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| Ras GEF | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| gamma-adaptin C-terminal appendage domain-like | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| Exostosin | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Interleukin-1 (IL-1) | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Variant RING domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| SMAD domain | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| HD domain | 0 | Direct |
| GYF domain | 0 | Direct |
| MIT domain | 0 | Direct |
| STAT DNA-binding domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| MBT repeat | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| CAD domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| RGC domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| R3H domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Splicing factor U2AF subunits | 0 | Direct |
| Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Ecto-ART | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| TSP-1 type 1 repeat | 0.0006587 | Direct |
| Tandem AAA-ATPase domain | 0.01271 | Inherited |
| Tyrosine-dependent oxidoreductases | 0.01648 | Inherited |
| Leucine zipper domain | 0.01966 | Inherited |
| Growth factor receptor domain | 0.02453 | Inherited |
| Calponin-homology domain, CH-domain | 0.03234 | Inherited |
| Interleukin 8-like chemokines | 0.04573 | Inherited |
| PLC-like (P variant) | 0.05056 | Inherited |
| DEATH domain, DD | 0.05628 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.05628 | Inherited |
| Mitochondrial carrier | 0.06804 | Inherited |
| HMG-box | 0.06804 | Inherited |
| SNARE fusion complex | 0.07087 | Inherited |
| First domain of FERM | 0.07949 | Inherited |
| Motor proteins | 0.08047 | Inherited |
| Canonical RBD | 0.09508 | Inherited |
| Hemopexin-like domain | 0.09961 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.09961 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.09961 | Inherited |
| Third domain of FERM | 0.09975 | Inherited |
| Second domain of FERM | 0.1043 | Inherited |
| Nucleosome core histones | 0.1057 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.1214 | Inherited |
| Frizzled cysteine-rich domain | 0.1392 | Inherited |
| UDPGT-like | 0.1392 | Inherited |
| MMP N-terminal domain | 0.1549 | Inherited |
| Phosphate binding protein-like | 0.1549 | Inherited |
| Caspase recruitment domain, CARD | 0.1549 | Inherited |
| G proteins | 0.1617 | Inherited |
| Double-stranded RNA-binding domain (dsRBD) | 0.1729 | Inherited |
| Protein kinases, catalytic subunit | 0.2042 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.2142 | Inherited |
| Pleckstrin-homology domain (PH domain) | 0.2417 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.2566 | Inherited |
| Serpins | 0.2636 | Inherited |
| Acetylcholinesterase-like | 0.2648 | Inherited |
| Ephrin receptor ligand binding domain | 0.2648 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.2648 | Inherited |
| Dual specificity phosphatase-like | 0.2727 | Inherited |
| Caspase catalytic domain | 0.294 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.294 | Inherited |
| L-arabinose binding protein-like | 0.3029 | Inherited |
| Single strand DNA-binding domain, SSB | 0.3254 | Inherited |
| Actin/HSP70 | 0.3273 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.3606 | Inherited |
| Rap/Ran-GAP | 0.3606 | Inherited |
| RING finger domain, C3HC4 | 0.3638 | Inherited |
| FHA domain | 0.3934 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4001 | Inherited |
| Pancreatic lipase, N-terminal domain | 0.4001 | Inherited |
| SNF-like | 0.4203 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.4416 | Inherited |
| Glutathione peroxidase-like | 0.4513 | Inherited |
| AN1-like Zinc finger | 0.4897 | Inherited |
| EGF-type module | 0.5278 | Inherited |
| Proprotein convertase P-domain | 0.5397 | Inherited |
| L domain | 0.5397 | Inherited |
| Lipoxigenase N-terminal domain | 0.5397 | Inherited |
| Papain-like | 0.557 | Inherited |
| GLA-domain | 0.5961 | Inherited |
| Smc hinge domain | 0.5973 | Inherited |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0.5973 | Inherited |
| NADPH-cytochrome p450 reductase-like | 0.5973 | Inherited |
| Long-chain cytokines | 0.6365 | Inherited |
| DBL homology domain (DH-domain) | 0.6373 | Inherited |
| Chaperone J-domain | 0.674 | Inherited |
| Cytochrome P450 | 0.6757 | Inherited |
| Leukotriene A4 hydrolase catalytic domain | 0.6775 | Inherited |
| Ran-binding domain | 0.6775 | Inherited |
| MATH domain | 0.6775 | Inherited |
| Tropomyosin | 0.6898 | Inherited |
| Polo-box duplicated region | 0.7295 | Inherited |
| Enolase | 0.7295 | Inherited |
| Extended AAA-ATPase domain | 0.7427 | Inherited |
| Bromodomain | 0.762 | Inherited |
| Acetyl-CoA synthetase-like | 0.7797 | Inherited |
| Fatty acid binding protein-like | 0.7901 | Inherited |
| Galectin (animal S-lectin) | 0.7901 | Inherited |
| UBC-related | 0.8076 | Inherited |
| Fibroblast growth factors (FGF) | 0.811 | Inherited |
| Prefoldin | 0.8235 | Inherited |
| C1 set domains (antibody constant domain-like) | 0.8342 | Inherited |
| Ngr ectodomain-like | 0.8611 | Inherited |
| CCCH zinc finger | 0.8623 | Inherited |
| ets domain | 0.8847 | Inherited |
| ABC transporter transmembrane region | 0.8919 | Inherited |
| Cytochrome p450 reductase N-terminal domain-like | 0.8955 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.9068 | Inherited |
| MHC antigen-recognition domain | 0.9073 | Inherited |
| Tubulin, GTPase domain | 0.9153 | Inherited |
| Fibronectin type II module | 0.9173 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.9218 | Inherited |
| Fibronectin type III | 0.9219 | Inherited |
| Tubulin, C-terminal domain | 0.9352 | Inherited |
| S100 proteins | 0.937 | Inherited |
| Retinol binding protein-like | 0.937 | Inherited |
| PHD domain | 0.9398 | Inherited |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0.9519 | Inherited |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0.9519 | Inherited |
| ABC transporter ATPase domain-like | 0.9625 | Inherited |
| Penta-EF-hand proteins | 0.9668 | Inherited |
| Crotonase-like | 0.9668 | Inherited |
| SH2 domain | 0.9751 | Inherited |
| Biotinyl/lipoyl-carrier proteins and domains | 0.9823 | Inherited |
| I set domains | 0.991 | Inherited |
| TNF-like | 0.9948 | Inherited |
| Translational machinery components | 0.9977 | Inherited |
| C2 set domains | 0.9977 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| Cyclin | 1 | Inherited |
| Pyrin domain, PYD | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Interferons/interleukin-10 (IL-10) | 1 | Inherited |
| Homeodomain | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| Nicotinic receptor ligand binding domain-like | 1 | Inherited |
| Intermediate filament protein, coiled coil region | 1 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | Inherited |
| Classic zinc finger, C2H2 | 1 | Inherited |
| Voltage-gated potassium channels | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| MOSC N-terminal domain-like | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Hermes dimerisation domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Virus ectodomain | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| Saposin | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Probable bacterial effector-binding domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| GDNF receptor-like | 0 | DIRECT |
| Lipoxigenase | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| TSP-1 type 1 repeat | 0.0004972 | DIRECT |
| Growth factor receptor domain | 0.001638 | INHERITED FROM: Triclosan || Benzamides || napabucasin || Curcumin || Chloromercuribenzoates || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Diarylheptanoids |
| NAD(P)-binding Rossmann-fold domains | 0.003294 | INHERITED FROM: 1,2-naphthoquinone || 2,4-dibromophenol || K 7174 || 2-bromophenol || 2,2',3,4',5',6-hexachlorobiphenyl || Benzophenones || Fenofibrate || 3,3',4,4',5,5'-hexabromobiphenyl || 2,6-dichloro-4-nitrophenol || 9,10-phenanthrenequinone || DEET || Polycyclic Aromatic Hydrocarbons || 2,6-dibromophenol || methyl salicylate || 3,3',4,4'-tetrabromobiphenyl || Pentachlorophenol |
| PLP-dependent transferases | 0.009561 | INHERITED FROM: K 7174 || Naphthoquinones |
| BAR/IMD domain-like | 0.01109 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Plexin repeat | 0.01239 | INHERITED FROM: Triclosan |
| (Phosphotyrosine protein) phosphatases II | 0.01552 | INHERITED FROM: ortho-Aminobenzoates || Benzo(a)pyrene || Sertraline || 2-(oxalylamino)benzoic acid || 1-Naphthylamine || Aminobenzoates || anthranilic acid || nitrophenylphosphate |
| Leucine zipper domain | 0.01642 | INHERITED FROM: Lignans || Mercuribenzoates || Chlorodiphenyl (54% Chlorine) || Chlorobenzoates || nectandrin-B || Biphenyl Compounds || Sulindac || Naphthalenes || Styrene || 1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one || Sertraline || 1-Naphthylamine || Benzophenones || Anthracenes || Stilbenes || Terphenyl Compounds || 1-nitropyrene || Benzylidene Compounds || Chloromercuribenzoates || NSC668394 || Benzenesulfonates || Benzoates || Chlorobenzenes || tamibarotene || Catechols || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Hydroxybenzoates || Fibric Acids || Phenylurea Compounds || Nitrobenzenes || Dinitrobenzenes || Carbaryl || Diarylheptanoids |
| PH domain-like | 0.02556 | INHERITED FROM: Pyrenes || 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Daunorubicin || Polycyclic Aromatic Hydrocarbons |
| Calponin-homology domain, CH-domain | 0.02735 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || Polycyclic Aromatic Hydrocarbons |
| FnI-like domain | 0.02977 | INHERITED FROM: Benzamides || Stilbenes || Simvastatin || Lovastatin || Phenylurea Compounds |
| Sema domain | 0.03372 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
| GTPase activation domain, GAP | 0.03839 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Polycyclic Aromatic Hydrocarbons |
| Interleukin 8-like chemokines | 0.03899 | INHERITED FROM: BIRB 796 || Chlorophenols || Polyphenols || Benzylamines || Tosyllysine Chloromethyl Ketone || Dibenzocycloheptenes || Terfenadine || Benzocycloheptenes || hydroxyhydroquinone || 3-chlorophenol || 3-nitrofluoranthene || 3-aminofluoranthene || Biphenyl Compounds || Minocycline || Phenanthrenes || Styrene || Oxytetracycline || sirtinol || Telmisartan || meclocycline || Polychlorinated Biphenyls || polydatin || acteoside || Styrenes || Fluorenes || fexofenadine || Tetracyclines || Simvastatin || 1-nitropyrene || Benzylidene Compounds || beta-hydroxy simvastatin acid || Zearalenone || Halogenated Diphenyl Ethers || Catecholamines || Chlorobenzenes || Catechols || Hydrolyzable Tannins || Isoproterenol || Morphine Derivatives || Toluene 2,4-Diisocyanate || Hydroxybenzoates || Morphinans || 3,4,5,3',4'-pentachlorobiphenyl || butenafine || Imatinib Mesylate || Terbinafine || catechol || Nitrobenzenes || Chrysenes || Dinitrobenzenes || Roflumilast || roflumilast N-oxide |
| Mitochondrial carrier | 0.05377 | INHERITED FROM: Abietanes || dehydroabietylamine |
| HMG-box | 0.05909 | INHERITED FROM: Polyphenols || Lignans || methylparaben |
| Histone-fold | 0.061 | INHERITED FROM: bisphenol A || 2,3-bis(3'-hydroxybenzyl)butyrolactone || decabromobiphenyl ether || Naphthoquinones || Benzhydryl Compounds |
| SNARE fusion complex | 0.06161 | INHERITED FROM: Heroin || Morphine Derivatives || Morphinans |
| RNA-binding domain, RBD | 0.06631 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || 2,3,5-(triglutathion-S-yl)hydroquinone || 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol || Dihydroxydihydrobenzopyrenes |
| Second domain of FERM | 0.07708 | INHERITED FROM: Pyrenes || Benzopyrenes |
| Cysteine-rich domain | 0.08321 | INHERITED FROM: puag-haad || 2,2',4,4',5-brominated diphenyl ether || Emodin |
| Integrin alpha N-terminal domain | 0.08739 | INHERITED FROM: Tetracycline || napabucasin || Tetracyclines |
| Hemopexin-like domain | 0.08739 | INHERITED FROM: hydroquinone || 3,3',4,5'-tetrahydroxystilbene || Doxycycline || Chloramphenicol || Phloroglucinol || bis(4-hydroxycinnamoyl)methane || demethoxycurcumin || Anthracenes || Silybin || Benzene || Tetracyclines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Simvastatin || Benzylidene Compounds || Flavonolignans || Benzenesulfonates || Catechols || Lovastatin || Phenylurea Compounds || Nitrobenzenes || Tyrphostins || pyrazolanthrone || Diarylheptanoids |
| BRCT domain | 0.08739 | INHERITED FROM: Etoposide || riccardin D || Daunorubicin || Anthracyclines || Pyrogallol || Benzyl Compounds || myristicin |
| Periplasmic binding protein-like II | 0.09794 | INHERITED FROM: Dibenzocycloheptenes || Benzocycloheptenes || Dizocilpine Maleate |
| Ran binding protein zinc finger-like | 0.09794 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
| Rhodanese/Cell cycle control phosphatase | 0.09794 | INHERITED FROM: pifithrin || Naphthalenes || Sertraline || 1-Naphthylamine || riccardin D || 2-(2-hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.1099 | INHERITED FROM: Dopamine || riccardin D || VER-246608 || tamibarotene || Catechols || Raloxifene Hydrochloride || Diarylheptanoids |
| GroES-like | 0.1099 | INHERITED FROM: Naphthols || Chlorophenols || walrycin A || Benz(a)Anthracenes || Benzophenones || Fenofibrate || Chlorobenzenes || Pentachlorophenol |
| Frizzled cysteine-rich domain | 0.1231 | INHERITED FROM: Chlorophenols || tetrachlorodian || Mitoxantrone |
| PGBD-like | 0.1377 | INHERITED FROM: hydroquinone || 3,3',4,5'-tetrahydroxystilbene || Doxycycline || Chloramphenicol || RTKI cpd || Phloroglucinol || bis(4-hydroxycinnamoyl)methane || demethoxycurcumin || Benzophenones || Anthracenes || Silybin || Hydroquinones || Fenofibrate || Benzene || Tetracyclines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Simvastatin || Benzylidene Compounds || Flavonolignans || Benzenesulfonates || Chlorobenzenes || Catechols || Lovastatin || Fibric Acids || Phenylurea Compounds || Nitrobenzenes || Toluene || Tyrphostins || pyrazolanthrone || Diarylheptanoids |
| PUA domain-like | 0.1377 | INHERITED FROM: K 7174 |
| SMAD/FHA domain | 0.1419 | INHERITED FROM: Polyphenols || Chlorodiphenyl (54% Chlorine) || sirtinol || Benzopyrenes || Aristolochic Acids || Pyrogallol |
| Periplasmic binding protein-like I | 0.19 | INHERITED FROM: Dibenzocycloheptenes || Dizocilpine Maleate || lactisole |
| A DNA-binding domain in eukaryotic transcription factors | 0.192 | INHERITED FROM: Dinitrochlorobenzene || Vitamin K || Resveratrol || Sertraline || 1-Naphthylamine || Vitamin K 3 || Fenofibrate || Chloromercuribenzoates || 4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol || Benzoates || Chlorobenzenes || Catechols || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Hydroxybenzoates || Nitrobenzenes || Dinitrobenzenes || Diarylheptanoids || 4-(E)-((p-tolylimino)-methylbenzene-1,2-diol) |
| Nucleic acid-binding proteins | 0.2126 | INHERITED FROM: Lignans || riccardin D || Anisoles |
| Caspase-like | 0.2149 | INHERITED FROM: Loratadine || FLLL 32 || bakuchiol || 3,3',4,5'-tetrahydroxystilbene || honokiol || Masoprocol || Polyphenols || dehydroxymethylepoxyquinomicin || pifithrin || ABT-737 || Lignans || Dibenzocycloheptenes || Terfenadine || Benzocycloheptenes || NCQ 344 || Donepezil || BDMC-A || Vitamin K || 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane || 2,4,3',5'-tetramethoxystilbene || Parabens || Phenol || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || propylparaben || NSC 680410 || 3,4,5,4'-tetramethoxystilbene || Win 55212-2 || Bromobenzoates || Stilbestrols || Biphenyl Compounds || Sulindac || Naphthalenes || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || Phenanthrenes || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Resveratrol || Sertraline || 1-Naphthylamine || Cyproheptadine || Fenamates || Sorafenib || Boc-D-FMK || Capsaicin || Anthracenes || 4-(3,5-dimethoxystyryl)phenyl acetate || Hydroquinones || Nitrophenols || Niflumic Acid || gingerol || Remoxipride || Indenes || Stilbenes || WP 631 || sesamol || Morphine || Aminobenzoates || Benzylidene Compounds || Anthraquinones || Zearalenone || Pyrogallol || Halogenated Diphenyl Ethers || Tosyl Compounds || Flavonolignans || Catecholamines || Benzenesulfonates || sulindac sulfide || Propranolol || Allylbenzene Derivatives || Catechols || fosbretabulin || Lovastatin || Cresols || Isoproterenol || Morphine Derivatives || Hydroxybenzoates || Polybrominated Biphenyls || Phenylurea Compounds || Thymol || Imatinib Mesylate || Anacardic Acids || 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea || 3-bromoacetylamino benzoic acid ethyl ester || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || catechol || suillin || Nitrobenzenes || Toluene || 10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone || Benzyl Compounds || pyrazolanthrone || 1,4-anthraquinone || Diarylheptanoids || Epirubicin || Humic Substances || NCX 4040 || 5-OH-BDE-47 |
| Serpins | 0.2215 | INHERITED FROM: 2,3-dimethoxy-1,4-naphthoquinone || 1-Naphthylisothiocyanate |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2311 | INHERITED FROM: Loratadine || Naphthols || 2,6-dihydroxyanthraquinone || Masoprocol || shikonin || plumbagin || Dibenzocycloheptenes || Benzocycloheptenes || Clofibric Acid || ortho-Aminobenzoates || Chlorodiphenyl (54% Chlorine) || dibenzo(a,l)pyrene || Hydroxyestrones || Biphenyl Compounds || Sulindac || Naphthalenes || Vanillic Acid || Phenanthrenes || alizarin || sulindac sulfone || Diflunisal || 4,4'-hexafluorisopropylidene diphenol || Phloroglucinol || 3-hydroxydesloratadine || Cyproheptadine || Fenamates || Benz(a)Anthracenes || Methylcholanthrene || Anthracenes || Silybin || Nitrophenols || anthrarobin || entacapone || Anthralin || 1-naphthol || Terphenyl Compounds || Naproxen || Phloretin || glabridin || Morphine || Aminobenzoates || Anthraquinones || Polychloroterphenyl Compounds || 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene || Aroclors || Zearalenone || Flavonolignans || pterostilbene || 1-hydroxypyrene || methyl salicylate || Salicylic Acid || 1,2,5,8-tetrahydroxy anthraquinone || Catechols || 4-nitrophenol || 1,4-dihydroxyanthraquinone || Morphine Derivatives || Morphinans || Fibric Acids || Carbanilides || Thymol || triclocarban || Estrogens, Catechol || Naphthaleneacetic Acids || Hydroxybenzoate Ethers || Flurbiprofen || 4-hydroxyestrone || alloin |
| GroEL apical domain-like | 0.2391 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| GroEL equatorial domain-like | 0.2391 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Bcl-2 inhibitors of programmed cell death | 0.2391 | INHERITED FROM: Plicamycin || Polyphenols || Triiodobenzoic Acids || Tetrahydronaphthalenes || ABT-737 || Safrole || 2,4,5,2',4',5'-hexachlorobiphenyl || 6-OH-BDE-47 || ortho-Aminobenzoates || bicalutamide || Parabens || Iodobenzoates || gyrophoric acid || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || propylparaben || 3,4,5,4'-tetramethoxystilbene || AH 23848 || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || acetochlor || Biphenyl Compounds || Sulindac || Naphthalenes || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || Phenanthrenes || Aspirin || 1'-acetoxychavicol acetate || Resveratrol || BP-1-102 || 1-Naphthylamine || naphtho(1,2-b)furan-4,5-dione || 2,2',4,4'-tetrabromodiphenyl ether || Etoposide || Fenamates || Sorafenib || Capsaicin || Podophyllotoxin || tetracycline CMT-3 || Anthracenes || Silybin || danthron || Nitrophenols || Fenofibrate || 3,4,5,4'-tetrahydroxystilbene || gingerol || Indenes || Styrenes || Fluorenes || Stilbenes || benzo(a)pyrene diolepoxide I || N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate || Tetracyclines || Morphine || Aminobenzoates || Benzylidene Compounds || Anthraquinones || Halogenated Diphenyl Ethers || Flavonolignans || pterostilbene || Catecholamines || Benzyl Alcohols || Allylbenzene Derivatives || Catechols || atranorin || 2-(2-hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone || Hydrolyzable Tannins || Isoproterenol || Morphine Derivatives || Hydroxybenzoates || Morphinans || Polybrominated Biphenyls || Phenylurea Compounds || 2,2-bis(4-glycidyloxyphenyl)propane || Toluidines || Imatinib Mesylate || salvin || Toluene || Benzyl Compounds || shogaol || Tyrphostins || pyrazolanthrone || Diarylheptanoids || 9,10-anthraquinone |
| TNF receptor-like | 0.2589 | INHERITED FROM: Polyphenols || Parabens || 3,4,5,4'-tetramethoxystilbene || Stilbestrols || Biphenyl Compounds || Aspirin || 2,2',4,4'-tetrabromodiphenyl ether || Benzophenones || aloe emodin || Fenofibrate || Stilbenes || Benzylidene Compounds || butylphen || Catechols || Hydroxybenzoates || Polybrominated Biphenyls || Fibric Acids || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Diarylheptanoids || 5-OH-BDE-47 |
| Protein kinase-like (PK-like) | 0.266 | INHERITED FROM: 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione || Pyrenes || liposomal doxorubicin || Polyphenols || Triiodobenzoic Acids || pifithrin || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Benzocycloheptenes || Iodobenzoates || puag-haad || 6,7-dimethoxy-3-phenylquinoxaline || NSC 680410 || Win 55212-2 || anethole || labedipinedilol A || afimoxifene || Biphenyl Compounds || Naphthalenes || tylophorine || 2-aminodiphenyl || 2''-galloylhyperin || picropodophyllin || Sorafenib || 4-vinyl-2,6-dimethoxyphenol || Capsaicin || Hexachlorobenzene || 5-7-oxo-zeaenol || napabucasin || Polychlorinated Biphenyls || Indenes || AG-012986 || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || Stilbenes || Polycyclic Aromatic Hydrocarbons || Benzylidene Compounds || tamibarotene || vaticanol C || Catechols || N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide || Hydroxybenzoates || Phenylurea Compounds || chrysophanic acid || Imatinib Mesylate || ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate || 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide || Benzyl Compounds || Diarylheptanoids || 5-OH-BDE-47 || 2,2',4,6,6'-pentachlorobiphenyl |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2673 | INHERITED FROM: GW 7647 |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.2852 | INHERITED FROM: isobutylparaben || phenanthrene || bakuchiol || Chlorophenols || 2,4,2',4'-tetrachlorobiphenyl || Aclarubicin || tetrachlorodian || 2,4,5,2',5'-pentachlorobiphenyl || Trityl Compounds || Hexestrol || tribromodiphenyl ether 28 || Zeranol || ethyl-p-hydroxybenzoate || Clofibrate || 2,2',4,4'-tetrahydroxybenzophenone || 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane || acetyl methyl tetramethyl tetralin || Chlorobenzoates || fenpyroximate || 4-nonylphenol || 2,2',4,4',5-brominated diphenyl ether || pirarubicin || Phenolphthaleins || Idarubicin || 2-tert-butylphenol || pencycuron || 4-ethylphenol || Naphthalenes || 1,1-bis(4-hydroxyphenyl)cyclohexane || 2,2-di(4-methacryloxyphenyl)propane || Gemfibrozil || nonylphenol || AGN 193109 || sulindac sulfone || EPI 001 || 4,4'-hexafluorisopropylidene diphenol || isobutyl-4-hydroxybenzoate || 4-tert-octylphenol || bisphenol B || Clomiphene || hexabrominated diphenyl ether 153 || Dihydrostilbenoids || Benzophenones || Anthracenes || Benzamides || Silybin || 2-phenylphenol || benzylparaben || 2,2',3,5',6-pentachlorobiphenyl || Indenes || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || tetralin || Stilbenes || homosalate || pentabrominated diphenyl ether 100 || chlormethoxynil || 3,4,3',4'-tetrachloroazobenzene || Butylated Hydroxyanisole || bifenox || versalide || 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene || aroclor 1260 || Tritolyl Phosphates || 4-cumylphenol || 3-benzylidene camphor || pyrene || butylphen || 2,4,6-trichlorophenyl 4-nitrophenyl ether || 4,4'-bisphenol F || Permethrin || Resorcinols || Zearalenone || Ro 41-5253 || Toremifene || Benzoates || phantolid || Chlorobenzenes || 3,5-di-tert-butyl-4-hydroxybenzaldehyde || dioxybenzone || 2,4,6-trichlorophenyl-4'-aminophenyl ether || Cresols || p-tert-amylphenol || 2,2',3,3',4,4',5-heptachlorobiphenyl || Fibric Acids || Dicofol || SR 11237 || 4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid || 2,2-bis(4-glycidyloxyphenyl)propane || nitrofen || 3-phenoxybenzoic acid || Toluidines || Bexarotene || triclocarban || 4-octylphenol || 4-phenylphenol || 2,3',4,4',5-pentachlorobiphenyl || Bibenzyls || Bezafibrate || oxybenzone || Carbaryl || Diarylheptanoids || Epirubicin || 2,6-diisopropylnaphthalene |
| Leukotriene A4 hydrolase N-terminal domain | 0.2969 | INHERITED FROM: 2-Naphthylamine |
| GroEL-intermediate domain like | 0.2969 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Rap/Ran-GAP | 0.3298 | INHERITED FROM: Dihydroxydihydrobenzopyrenes |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.3301 | INHERITED FROM: Masoprocol |
| Kazal-type serine protease inhibitors | 0.3321 | INHERITED FROM: Rosuvastatin Calcium || Phenolphthaleins || Fluorobenzenes || Sulfobromophthalein |
| MFS general substrate transporter | 0.3502 | INHERITED FROM: Sulpiride || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Rosuvastatin Calcium || Phenolphthaleins || Hippurates || 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid || p-Aminohippuric Acid || Fluorobenzenes || 7-(deoxyadenosin-N(6)-yl)aristolactam I || Fenamates || Amitriptyline || Bumetanide || Diphenhydramine || Norepinephrine || 2,2',4,4',5,6'-hexabromodiphenyl ether || Sulfobromophthalein || Naproxen || Tetracyclines || Phloretin || 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid || Aminobenzoates || Propranolol || Salicylic Acid || Aminohippuric Acids || Naphthaleneacetic Acids |
| EF-hand | 0.3662 | INHERITED FROM: entinostat || benzo(e)pyrene |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.367 | INHERITED FROM: 6-OH-BDE-47 || Biphenyl Compounds || Naphthalenes || Chloromercuribenzoates || Catecholamines || Chlorobenzenes || Catechols || Isoproterenol || Nitrobenzenes || Dinitrobenzenes |
| Six-hairpin glycosidases | 0.367 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
| Glycerol-3-phosphate (1)-acyltransferase | 0.3858 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || GW 7647 |
| SNF-like | 0.3858 | INHERITED FROM: indatraline || 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || Dopamine || Norepinephrine || Indans |
| ARM repeat | 0.3951 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || bisphenol F || Dihydroxydihydrobenzopyrenes |
| alpha/beta-Hydrolases | 0.404 | INHERITED FROM: Heroin || bis(4-nitrophenyl)phosphate || Nitrophenols || Morphine Derivatives || 6-O-monoacetylmorphine || Bisphenol A-Glycidyl Methacrylate |
| E2F-DP heterodimerization region | 0.4075 | INHERITED FROM: 6-OH-BDE-47 || Naphthalenes || Stilbenes || UF010 compound || 5-OH-BDE-47 |
| Kringle-like | 0.4367 | INHERITED FROM: alpha-benzoylamino-1,4-naphthoquinone || anethole || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Aspirin || bis(4-hydroxycinnamoyl)methane || demethoxycurcumin || Silybin || Norepinephrine || gingerol || Simvastatin || Flavonolignans || Benzenesulfonates || Propranolol || Isoproterenol || Hydroxybenzoates || Humic Substances |
| AN1-like Zinc finger | 0.4532 | INHERITED FROM: Anisoles |
| Cytokine | 0.4703 | INHERITED FROM: Suramin || ortho-Aminobenzoates || Naphthalenesulfonates || Phloroglucinol || Trinitrobenzenes || Anthracenes || Phloretin || Simvastatin || 1-nitropyrene || Tosyl Compounds || Flavonolignans || Lovastatin || Isoproterenol || 3,4,5,3',4'-pentachlorobiphenyl |
| DNA/RNA polymerases | 0.4817 | INHERITED FROM: Perylene || Benz(a)Anthracenes || Phenalenes |
| Actin-like ATPase domain | 0.4894 | INHERITED FROM: 6-OH-BDE-47 || Catecholamines |
| Prefoldin | 0.4914 | INHERITED FROM: ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid || Bexarotene |
| P-loop containing nucleoside triphosphate hydrolases | 0.5176 | INHERITED FROM: N-hydroxy-4-aminobiphenyl || 2,3,5-(triglutathion-S-yl)hydroquinone || 2,3-bis(3'-hydroxybenzyl)butyrolactone || riccardin D || Pyrogallol || 2-Acetylaminofluorene || 1-hydroxymethylpyrene || Benzyl Alcohol || Benzyl Compounds |
| EGF/Laminin | 0.5291 | INHERITED FROM: Triclosan || benzo(e)pyrene || Benzamides || Benzoates |
| Ubiquitin-like | 0.5357 | INHERITED FROM: ABT-737 || Benzopyrenes |
| GLA-domain | 0.5569 | INHERITED FROM: Tamoxifen |
| PAP/OAS1 substrate-binding domain | 0.5569 | INHERITED FROM: tamibarotene |
| Smc hinge domain | 0.5581 | INHERITED FROM: 2,3-bis(3'-hydroxybenzyl)butyrolactone |
| Polo-box domain | 0.5581 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Lignans || Curcumin || Dihydroxydihydrobenzopyrenes || Catechols || Benzyl Compounds || Diarylheptanoids |
| "Winged helix" DNA-binding domain | 0.5647 | INHERITED FROM: UF010 compound |
| Concanavalin A-like lectins/glucanases | 0.5896 | INHERITED FROM: Triclosan |
| DBL homology domain (DH-domain) | 0.598 | INHERITED FROM: benzo(e)pyrene |
| Enolase C-terminal domain-like | 0.6197 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
| HMA, heavy metal-associated domain | 0.6197 | INHERITED FROM: Naphthalenes |
| Enolase N-terminal domain-like | 0.6197 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
| PDZ domain-like | 0.6266 | INHERITED FROM: benzo(e)pyrene || Polycyclic Aromatic Hydrocarbons |
| Cytochrome P450 | 0.6308 | INHERITED FROM: Loratadine || physcione || phenanthrene || teriflunomide || Naphthols || chlorfluazuron || 3,3',4,5'-tetrahydroxystilbene || Chlorophenols || dimethocaine || shikonin || 2,4,5,2',5'-pentachlorobiphenyl || Benzylamines || Dibenzocycloheptenes || Xylenes || Benzocycloheptenes || tribromodiphenyl ether 28 || dibenzoanthracene-3,4-dihydrodiol || 1-chloropyrene || 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || estragole || 4-isopropylphenol || Dextromethorphan || 3,6-dinitrobenzopyrene || 6-chrysenamine || KN 93 || hyperforin || walrycin A || 2,4,3',5'-tetramethoxystilbene || Phenol || Chlorodiphenyl (54% Chlorine) || puag-haad || diphenyl || indeno(1,2,3-cd)pyrene || Biphenyl Compounds || 2,4-dibromophenol || Benzene Derivatives || Naphthalenes || 2,3,3',4,4',5-hexachlorobiphenyl || fimasartan || 2-dichlorobenzene || Phenanthrenes || Meclizine || Gemfibrozil || UAB 30 || 4,4'-cyclohexylidenebisphenol || 1,3-dinitropyrene || Styrene || 4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide || 6-nitrochrysene || alizarin || 5,12-naphthacenequinone || naphtho(2,3-a)pyrene || 4-methylchrysene || 4-biphenylamine || 3-methylchrysene || 6-methylchrysene || Sertraline || 4,4'-hexafluorisopropylidene diphenol || 2-(4-chloro-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine || Phloroglucinol || 1-Naphthylamine || pentachlorobenzene || 4-tert-octylphenol || Linuron || benzotriphenylene || 9-phenanthrol || purpurin || 2-bromophenol || styrofoam || acenaphthylene || Fenamates || pentabromophenol || 2,2',3,4',5',6-hexachlorobiphenyl || dimethoxycurcumin || Benz(a)Anthracenes || triflumuron || Benzophenones || 1,2,5,6-dibenzanthracene || Anthracenes || Silybin || 2-Naphthylamine || aloe emodin || Polychlorinated Biphenyls || Nitrophenols || dimemorfan || 4-(methylsulfinyl)phenol || triptolide || Indenes || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || Styrenes || 3,3',4,4',5,5'-hexabromobiphenyl || Fluorenes || Stilbenes || 2,6-dimethylnaphthalene || benzo(c)phenanthrene || 4-hydroxy-N-desmethyltamoxifen || epsilon-viniferin || 1-naphthol || Terphenyl Compounds || 5-methylchrysene || droloxifene || 1,2,4-trichlorobenzene || 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide || 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid || N,N-didesmethyl-4-hydroxytamoxifen || DEET || N-desmethyltamoxifen || anthracene || Dextrorphan || hexafluoron || 2,6-dibromophenol || Aminobenzoates || Anthraquinones || pyrene || 4-dichlorobenzene || Polychloroterphenyl Compounds || 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene || 4,4'-bisphenol F || Permethrin || Emodin || Aroclors || Orphenadrine || Pyrogallol || elemicin || zafirlukast || 3,4,5,3',4',5'-hexachlorobiphenyl || isoproturon || Indans || Propranolol || 3,3',4,4'-tetrabromobiphenyl || 1,4-naphthoquinone || Chlorobenzenes || Allylbenzene Derivatives || 2-nitroanisole || pinostilbene || 1-phenylazo-2-naphthol || 2,2',4,6'-tetramethoxystilbene || Cresols || trans-1,2-dihydro-1,2-naphthalenediol || 9,10-Dimethyl-1,2-benzanthracene || Morphinans || Fibric Acids || S-sulindac || Carbanilides || 2-nitrofluoranthene || 3,4,5,3',4'-pentachlorobiphenyl || Phenylurea Compounds || Toluidines || chrysophanic acid || Pentachlorophenol || Phenalenes || GW 3965 || 2,3',4,4',5-pentachlorobiphenyl || cumene hydroperoxide || 4-bromo-2-chlorophenol || Nitrobenzenes || Acenaphthenes || Bezafibrate || Toluene || 6-nitrobenzo(a)pyrene || Benzyl Compounds || naphthalene || dihydrocapsaicin || benzo(a)pyrene 7,8-dihydrodiol || Carbaryl || Diarylheptanoids || 2,4,6-tribromophenol || 2-nitrophenol |
| Chaperone J-domain | 0.6339 | INHERITED FROM: Carbaryl |
| Multidrug efflux transporter AcrB transmembrane domain | 0.6377 | INHERITED FROM: Simvastatin || Lovastatin |
| Tropomyosin | 0.6493 | INHERITED FROM: Mitoxantrone |
| FAD/NAD(P)-binding domain | 0.6539 | INHERITED FROM: juglone || Nitrobenzoates |
| UBC-like | 0.6777 | INHERITED FROM: K 7174 || Anisoles |
| Cystine-knot cytokines | 0.6879 | INHERITED FROM: Plicamycin || Procarbazine || Phenanthrenes || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Stilbenes || Tetracyclines || Simvastatin || Benzylidene Compounds || Zearalenone || Chlorobenzenes || Morphinans || Nitrobenzenes || aristolochic acid I || MOPP protocol |
| G protein-binding domain | 0.6882 | INHERITED FROM: K 7174 || Anisoles |
| Ribosomal L27 protein-like | 0.6882 | INHERITED FROM: K 7174 || Anisoles |
| SAP domain | 0.7133 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| Bromodomain | 0.7202 | INHERITED FROM: 4,4'-hexafluorisopropylidene diphenol |
| Flavoproteins | 0.7229 | INHERITED FROM: Indophenol || ortho-Aminobenzoates || Biphenyl Compounds || Phenanthrenes || Aspirin || Phloroglucinol || Salicylates || Fenamates || Benzoic Acid || Capsaicin || Benz(a)Anthracenes || Benzophenones || Polychlorinated Biphenyls || Fluorenes || Simvastatin || Aminobenzoates || pterostilbene || Catechols || Hydroxybenzoates || Fibric Acids || Chrysenes || Toluene |
| p53-like transcription factors | 0.7263 | INHERITED FROM: 3,3',4,5'-tetrahydroxystilbene || Polyphenols || Triiodobenzoic Acids || Terfenadine || Indophenol || Iodobenzoates || Iopamidol || 1'-acetoxychavicol acetate || Tosylphenylalanyl Chloromethyl Ketone || Resveratrol || benzo(a)pyrene-1,6-quinone || Salicylates || 1-Naphthylamine || Norepinephrine || WP 744 || Stilbenes || benzo(a)pyrene-3,6-quinone || Benzene || Morphine || Simvastatin || Benzylidene Compounds || 2-Acetylaminofluorene || Benzyl Alcohols || Benzenesulfonates || Chlorobenzenes || Catechols || Morphine Derivatives || Imatinib Mesylate || Anacardic Acids || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Nitrobenzenes || Acenaphthenes || Tyrphostins || Diarylheptanoids |
| Acetyl-CoA synthetase-like | 0.7378 | INHERITED FROM: Benzophenones || GW 7647 || Phenylurea Compounds |
| GST C-terminal domain-like | 0.7458 | INHERITED FROM: Dinitrochlorobenzene || isomethyleugenol || Dihydroxyphenylalanine || ortho-Aminobenzoates || dibenzo(a,l)pyrene || Naphthalenesulfonates || Fenamates || 2-allylphenol || 4-propylphenol || Aminobenzoates || Chlorobenzenes || cumene hydroperoxide || Nitrobenzenes || Cysteinyldopa || Dinitrobenzenes |
| PYP-like sensor domain (PAS domain) | 0.7861 | INHERITED FROM: Pyrenes || 3,3',4,5'-tetrahydroxystilbene || Polyphenols || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || Polychlorinated Biphenyls || Fluorenes || Benzocaine || Benzopyrenes || Aminobenzoates || Catecholamines || Benzoates || Catechols || Isoproterenol || Hydroxybenzoates || butamben || Diarylheptanoids |
| E set domains | 0.7947 | INHERITED FROM: Tosyllysine Chloromethyl Ketone || Naphthalenes |
| Nucleotidylyl transferase | 0.8075 | INHERITED FROM: Benzophenones || Fenofibrate || 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
| ABC transporter transmembrane region | 0.8213 | INHERITED FROM: Loratadine || tetrabromobisphenol A || Dibenzocycloheptenes || Terfenadine || Benzocycloheptenes || Zeranol || Metaproterenol || 4'-methoxy-1-naphthylfenoterol || Cyproheptadine || Etoposide || Benz(a)Anthracenes || Daunorubicin || Fluorenes || fexofenadine || Anthracyclines || 2-Acetylaminofluorene || Flavonolignans || Catecholamines || zafirlukast || Catechols || Cresols || Isoproterenol || Phenylurea Compounds || Pravastatin || Imatinib Mesylate || Bezafibrate || Benzyl Compounds || zearalenol || Epirubicin |
| CCCH zinc finger | 0.8213 | INHERITED FROM: 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
| Toll/Interleukin receptor TIR domain | 0.8505 | INHERITED FROM: 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || bis(4-hydroxycinnamoyl)methane || 9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Dinitrobenzenes || Diarylheptanoids |
| DEATH domain | 0.8604 | INHERITED FROM: bakuchiol || Polyphenols || Aclarubicin || dehydroxymethylepoxyquinomicin || Terfenadine || Parabens || Phenol || Chlorodiphenyl (54% Chlorine) || 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone || propylparaben || 3,4,5,4'-tetramethoxystilbene || Win 55212-2 || Stilbestrols || Biphenyl Compounds || Sulindac || Naphthalenes || 1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane || Phenanthrenes || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || tylophorine || 1'-acetoxychavicol acetate || Tosylphenylalanyl Chloromethyl Ketone || Sorafenib || Capsaicin || Anthracenes || aloe emodin || danthron || Polychlorinated Biphenyls || Stilbenes || Benzylidene Compounds || Anthraquinones || butylphen || Halogenated Diphenyl Ethers || Flavonolignans || Benzyl Alcohols || Allylbenzene Derivatives || Catechols || fosbretabulin || Lovastatin || Hydroxybenzoates || Polybrominated Biphenyls || Imatinib Mesylate || Anacardic Acids || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || suillin || Nitrobenzenes || Toluene || Benzyl Compounds || Diarylheptanoids || 5-OH-BDE-47 |
| MHC antigen-recognition domain | 0.8656 | INHERITED FROM: entinostat || Tetrahydronaphthalenes || Minocycline || Naphthalenes || Tetracyclines || tamibarotene |
| Lipocalins | 0.8656 | INHERITED FROM: Naphthalenesulfonates || 1-anilino-8-naphthalenesulfonate || Anilino Naphthalenesulfonates || 11-(dansylamino)undecanoic acid || Dansyl Compounds || Bezafibrate |
| ClpP/crotonase | 0.8731 | INHERITED FROM: GW 7647 || Phenylurea Compounds |
| Tubulin nucleotide-binding domain-like | 0.874 | INHERITED FROM: 2,4,3',5'-tetramethoxystilbene || resorcinol || dibenzo(a,l)pyrene || 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
| Fibronectin type III | 0.8811 | INHERITED FROM: Pyrenes || Triclosan || benzo(e)pyrene || 2-(oxalylamino)benzoic acid || Benzamides || Simvastatin |
| Tubulin C-terminal domain-like | 0.8936 | INHERITED FROM: 2,4,3',5'-tetramethoxystilbene || resorcinol || dibenzo(a,l)pyrene || 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
| Hairpin loop containing domain-like | 0.8955 | INHERITED FROM: Tamoxifen |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.8958 | INHERITED FROM: Polyphenols || Phloroglucinol || Hydroxydopamines || Capsaicin || N-(4-O-glycerol-3-methoxybenzyl)nonivamide |
| Riboflavin synthase domain-like | 0.8958 | INHERITED FROM: Polyphenols || Phloroglucinol || Hydroxydopamines || Capsaicin || N-(4-O-glycerol-3-methoxybenzyl)nonivamide |
| Thioredoxin-like | 0.9142 | INHERITED FROM: isomethyleugenol || Dihydroxyphenylalanine || dinocap || ortho-Aminobenzoates || dibenzo(a,l)pyrene || 2,2',4,4',5-brominated diphenyl ether || Fenamates || Anisoles || 2-allylphenol || 4-propylphenol || Chlorobenzenes || dichlone || cumene hydroperoxide || Nitrobenzenes || Cysteinyldopa |
| Voltage-gated potassium channels | 0.9251 | INHERITED FROM: Flufenamic Acid || Niflumic Acid || Propranolol || Mibefradil || Mexiletine |
| Cadherin-like | 0.931 | INHERITED FROM: Triclosan || dibenzo(a,l)pyrene |
| SH2 domain | 0.9358 | INHERITED FROM: honokiol || Polyphenols || Naphthalenes || benzo(a)pyrene-1,6-quinone || naphtho(1,2-b)furan-4,5-dione || WP1066 || 4-(3,5-dimethoxystyryl)phenyl acetate || benzo(a)pyrene-3,6-quinone || Simvastatin || Benzylidene Compounds || tamibarotene || Imatinib Mesylate |
| Single hybrid motif | 0.9425 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
| TNF-like | 0.9495 | INHERITED FROM: Plicamycin || Indophenol || 3,4,5,4'-tetramethoxystilbene || Biphenyl Compounds || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Diphenhydramine || aloe emodin || Curcumin || peroben || Lovastatin || diphenyliodonium || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Bezafibrate || Diarylheptanoids |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9587 | INHERITED FROM: Pyrenes |
| Metalloproteases ("zincins"), catalytic domain | 0.9621 | INHERITED FROM: Doxycycline || Chloramphenicol || RTKI cpd || PD 0325901 || Tetracyclines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Simvastatin || Tyrphostins || pyrazolanthrone |
| SH3-domain | 0.9628 | INHERITED FROM: honokiol || Benzo(a)pyrene || Benzopyrenes || 2,3',4,4',5-pentachlorobiphenyl |
| LDL receptor-like module | 0.971 | INHERITED FROM: tanshinone |
| Cyclin-like | 0.976 | INHERITED FROM: bicalutamide || Parabens || AGN 194204 || labedipinedilol A || Sulindac || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || tylophorine || Phloroglucinol || riccardin D || Silybin || gingerol || acteoside || Indenes || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || Stilbenes || aspidin BB || 3,5,3',4',5'-pentamethoxystilbene || UF010 compound || LG 100268 || Ro 41-5253 || Hydroxybenzoates || Polybrominated Biphenyls || Tyrphostins || 5-OH-BDE-47 |
| FYVE/PHD zinc finger | 0.9787 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide |
| Ribosomal protein S5 domain 2-like | 0.9876 | INHERITED FROM: riccardin D || tamibarotene |
| Intermediate filament protein, coiled coil region | 0.9909 | INHERITED FROM: Hydroquinones || ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid |
| Immunoglobulin | 0.998 | INHERITED FROM: 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Triclosan || HX 630 |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: 2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone || 1-(8-bromobenzo(1,2-b;4,5-b')difuran-4-yl)-2-aminopropane || 8-Hydroxy-2-(di-n-propylamino)tetralin || Norepinephrine || Epinephrine |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: resorcinol |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: 3,3',4,5'-tetrahydroxystilbene || Clofibrate || Phenol || Chlorobenzoates || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || Polychlorinated Biphenyls || 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid || Benzocaine || Fibric Acids || butamben |
| RNI-like | 1 | INHERITED FROM: 3,5-bis(2-fluorobenzylidene)piperidin-4-one |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | INHERITED FROM: tetrabromobisphenol A || 2,4,2',4'-tetrachlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 4-nonylphenol || 2,5,2',5'-tetrachlorobiphenyl || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || PCB 180 || 2,2',3,5',6-pentachlorobiphenyl || 2,4,4'-trichlorobiphenyl || Propofol || benzamide || Polybrominated Biphenyls || 4-octylphenol || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || Toluene |
| Nicotinic receptor ligand binding domain-like | 1 | INHERITED FROM: tetrabromobisphenol A || 2,4,2',4'-tetrachlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 4-nonylphenol || 2,5,2',5'-tetrachlorobiphenyl || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || PCB 180 || 2,2',3,5',6-pentachlorobiphenyl || 2,4,4'-trichlorobiphenyl || Propofol || benzamide || Polybrominated Biphenyls || 4-octylphenol || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || Toluene |
| 4-helical cytokines | 1 | INHERITED FROM: Polyphenols || Benzylamines || Dibenzocycloheptenes || Terfenadine || Benzocycloheptenes || FEC protocol || 4-nonylphenol || Biphenyl Compounds || Phenanthrenes || Phloroglucinol || FK 706 || Trinitrobenzenes || 2-tert-butylhydroquinone || Anthracenes || Polychlorinated Biphenyls || Stilbenes || Benzene || Phloretin || Simvastatin || Aminobenzoates || Benzylidene Compounds || Ro 41-5253 || Propofol || Flavonolignans || Catecholamines || Catechols || Lovastatin || Isoproterenol || Hydroxybenzoates || Morphinans || 2,2',3',4,4',5-hexachlorobiphenyl || Sodium Salicylate || Tyrphostins || Diarylheptanoids || Epirubicin |
| Homeodomain-like | 1 | INHERITED FROM: Triclosan || Mercuribenzoates || Chloromercuribenzoates |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: resorcinol |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| MOSC N-terminal domain-like | 0 | Direct |
| AlbA-like | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| BEACH domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| ARID-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| CalX-like | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| PUG domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| DNA clamp | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| WW domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Release factor | 0 | Direct |
| PAH2 domain | 0 | Direct |
| AhpD-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| KA1-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| LanC-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| BAG domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| DLC | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| PRTase-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Hermes dimerisation domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| Proteasome activator | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| HRDC-like | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| PKD domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| FF domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| LCCL domain | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Connexin43 | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| BSD domain-like | 0 | Direct |
| GYF domain | 0 | Direct |
| BTG domain-like | 0 | Direct |
| ClpS-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Notch domain | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| R3H domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| TIMP-like | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Virus ectodomain | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Stathmin | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| ITPase-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| SIS domain | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| SRF-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Metallothionein | 0 | Direct |
| Annexin | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| PapD-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| GFP-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Pentein | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Aldolase | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| N-(deoxy)ribosyltransferase-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| Saposin | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| DUSP-like | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Sec7 domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| AXH domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Probable bacterial effector-binding domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| PEBP-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| PWI domain | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| STAT | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| BolA-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| RGC domain-like | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Mss4-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Nop domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| GDNF receptor-like | 0 | Direct |
| Lipoxigenase | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| WGR domain-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| ISP domain | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| TSP-1 type 1 repeat | 0.0004972 | Direct |
| Growth factor receptor domain | 0.001638 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.003294 | Inherited |
| PLP-dependent transferases | 0.009561 | Inherited |
| BAR/IMD domain-like | 0.01109 | Inherited |
| Plexin repeat | 0.01239 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.01552 | Inherited |
| Leucine zipper domain | 0.01642 | Inherited |
| PH domain-like | 0.02556 | Inherited |
| Calponin-homology domain, CH-domain | 0.02735 | Inherited |
| FnI-like domain | 0.02977 | Inherited |
| Sema domain | 0.03372 | Inherited |
| GTPase activation domain, GAP | 0.03839 | Inherited |
| Interleukin 8-like chemokines | 0.03899 | Inherited |
| Mitochondrial carrier | 0.05377 | Inherited |
| HMG-box | 0.05909 | Inherited |
| Histone-fold | 0.061 | Inherited |
| SNARE fusion complex | 0.06161 | Inherited |
| RNA-binding domain, RBD | 0.06631 | Inherited |
| Second domain of FERM | 0.07708 | Inherited |
| Cysteine-rich domain | 0.08321 | Inherited |
| Integrin alpha N-terminal domain | 0.08739 | Inherited |
| Hemopexin-like domain | 0.08739 | Inherited |
| BRCT domain | 0.08739 | Inherited |
| Periplasmic binding protein-like II | 0.09794 | Inherited |
| Ran binding protein zinc finger-like | 0.09794 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.09794 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.1099 | Inherited |
| GroES-like | 0.1099 | Inherited |
| Frizzled cysteine-rich domain | 0.1231 | Inherited |
| PGBD-like | 0.1377 | Inherited |
| PUA domain-like | 0.1377 | Inherited |
| SMAD/FHA domain | 0.1419 | Inherited |
| Periplasmic binding protein-like I | 0.19 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.192 | Inherited |
| Nucleic acid-binding proteins | 0.2126 | Inherited |
| Caspase-like | 0.2149 | Inherited |
| Serpins | 0.2215 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2311 | Inherited |
| GroEL apical domain-like | 0.2391 | Inherited |
| GroEL equatorial domain-like | 0.2391 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.2391 | Inherited |
| TNF receptor-like | 0.2589 | Inherited |
| Protein kinase-like (PK-like) | 0.266 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2673 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.2852 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.2969 | Inherited |
| GroEL-intermediate domain like | 0.2969 | Inherited |
| Rap/Ran-GAP | 0.3298 | Inherited |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.3301 | Inherited |
| Kazal-type serine protease inhibitors | 0.3321 | Inherited |
| MFS general substrate transporter | 0.3502 | Inherited |
| EF-hand | 0.3662 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.367 | Inherited |
| Six-hairpin glycosidases | 0.367 | Inherited |
| Glycerol-3-phosphate (1)-acyltransferase | 0.3858 | Inherited |
| SNF-like | 0.3858 | Inherited |
| ARM repeat | 0.3951 | Inherited |
| alpha/beta-Hydrolases | 0.404 | Inherited |
| E2F-DP heterodimerization region | 0.4075 | Inherited |
| Kringle-like | 0.4367 | Inherited |
| AN1-like Zinc finger | 0.4532 | Inherited |
| Cytokine | 0.4703 | Inherited |
| DNA/RNA polymerases | 0.4817 | Inherited |
| Actin-like ATPase domain | 0.4894 | Inherited |
| Prefoldin | 0.4914 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.5176 | Inherited |
| EGF/Laminin | 0.5291 | Inherited |
| Ubiquitin-like | 0.5357 | Inherited |
| GLA-domain | 0.5569 | Inherited |
| PAP/OAS1 substrate-binding domain | 0.5569 | Inherited |
| Smc hinge domain | 0.5581 | Inherited |
| Polo-box domain | 0.5581 | Inherited |
| "Winged helix" DNA-binding domain | 0.5647 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.5896 | Inherited |
| DBL homology domain (DH-domain) | 0.598 | Inherited |
| Enolase C-terminal domain-like | 0.6197 | Inherited |
| HMA, heavy metal-associated domain | 0.6197 | Inherited |
| Enolase N-terminal domain-like | 0.6197 | Inherited |
| PDZ domain-like | 0.6266 | Inherited |
| Cytochrome P450 | 0.6308 | Inherited |
| Chaperone J-domain | 0.6339 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.6377 | Inherited |
| Tropomyosin | 0.6493 | Inherited |
| FAD/NAD(P)-binding domain | 0.6539 | Inherited |
| UBC-like | 0.6777 | Inherited |
| Cystine-knot cytokines | 0.6879 | Inherited |
| G protein-binding domain | 0.6882 | Inherited |
| Ribosomal L27 protein-like | 0.6882 | Inherited |
| SAP domain | 0.7133 | Inherited |
| Bromodomain | 0.7202 | Inherited |
| Flavoproteins | 0.7229 | Inherited |
| p53-like transcription factors | 0.7263 | Inherited |
| Acetyl-CoA synthetase-like | 0.7378 | Inherited |
| GST C-terminal domain-like | 0.7458 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.7861 | Inherited |
| E set domains | 0.7947 | Inherited |
| Nucleotidylyl transferase | 0.8075 | Inherited |
| ABC transporter transmembrane region | 0.8213 | Inherited |
| CCCH zinc finger | 0.8213 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.8505 | Inherited |
| DEATH domain | 0.8604 | Inherited |
| MHC antigen-recognition domain | 0.8656 | Inherited |
| Lipocalins | 0.8656 | Inherited |
| ClpP/crotonase | 0.8731 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.874 | Inherited |
| Fibronectin type III | 0.8811 | Inherited |
| Tubulin C-terminal domain-like | 0.8936 | Inherited |
| Hairpin loop containing domain-like | 0.8955 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.8958 | Inherited |
| Riboflavin synthase domain-like | 0.8958 | Inherited |
| Thioredoxin-like | 0.9142 | Inherited |
| Voltage-gated potassium channels | 0.9251 | Inherited |
| Cadherin-like | 0.931 | Inherited |
| SH2 domain | 0.9358 | Inherited |
| Single hybrid motif | 0.9425 | Inherited |
| TNF-like | 0.9495 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9587 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.9621 | Inherited |
| SH3-domain | 0.9628 | Inherited |
| LDL receptor-like module | 0.971 | Inherited |
| Cyclin-like | 0.976 | Inherited |
| FYVE/PHD zinc finger | 0.9787 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.9876 | Inherited |
| Intermediate filament protein, coiled coil region | 0.9909 | Inherited |
| Immunoglobulin | 0.998 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 1 | Inherited |
| RNI-like | 1 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | Inherited |
| Nicotinic receptor ligand binding domain-like | 1 | Inherited |
| 4-helical cytokines | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
54928,90209
54928 - RNA-binding domain, RBD
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
47353,109640
47353 - Retrovirus capsid dimerization domain-like
109640 - KRAB domain (Kruppel-associated box) | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | DIRECT |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
54416,54416
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | DIRECT |
102848,54236
102848 - NSFL1 (p97 ATPase) cofactor p47, SEP domain
54236 - Ubiquitin-like | 0 | DIRECT |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
141072,141072
141072 - CalX-like
141072 - CalX-like | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
48670,48097
48670 - Transducin (heterotrimeric G protein), gamma chain
48097 - Regulator of G-protein signaling, RGS | 0 | DIRECT |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | DIRECT |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
48452,48371
48452 - TPR-like
48371 - ARM repeat | 0 | DIRECT |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | DIRECT |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | DIRECT |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | DIRECT |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
48065,103657
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like | 0 | DIRECT |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
53300,69179
53300 - vWA-like
69179 - Integrin domains | 0 | DIRECT |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | DIRECT |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
103657,48350
103657 - BAR/IMD domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
100895,50494
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | DIRECT |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
48371,101447
48371 - ARM repeat
101447 - Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
57581,57581
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | DIRECT |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | DIRECT |
81837,50978
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | DIRECT |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
57196,56496
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | DIRECT |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
57196,69687
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
54695,54695
54695 - POZ domain
54695 - POZ domain | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
47113,-7
47113 - Histone-fold
-7 - CATH | 0 | DIRECT |
49410,50242
49410 - Alpha-macroglobulin receptor domain
50242 - TIMP-like | 0 | DIRECT |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | DIRECT |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,46785
50729 - PH domain-like
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
100895,48726
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | DIRECT |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | DIRECT |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49695,50370
49695 - gamma-Crystallin-like
50370 - Ricin B-like lectins | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
56496,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
54416,49998
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
50104,50249
50104 - Translation proteins SH3-like domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | DIRECT |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
63763,57903
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
49299,49299
49299 - PKD domain
49299 - PKD domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | DIRECT |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | DIRECT |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | DIRECT |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | DIRECT |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | DIRECT |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | DIRECT |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
81901,81901
81901 - HCP-like
81901 - HCP-like | 0 | DIRECT |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
47576,140612
47576 - Calponin-homology domain, CH-domain
140612 - EB1 dimerisation domain-like | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
51905,47576
51905 - FAD/NAD(P)-binding domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | DIRECT |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | DIRECT |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | DIRECT |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | DIRECT |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | DIRECT |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | DIRECT |
48452,46785
48452 - TPR-like
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47862,47862
47862 - Saposin
47862 - Saposin | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
55186,55681
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
47576,143575
47576 - Calponin-homology domain, CH-domain
143575 - GAS2 domain-like | 0 | DIRECT |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | DIRECT |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | DIRECT |
50370,57440
50370 - Ricin B-like lectins
57440 - Kringle-like | 0 | DIRECT |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
57440,56436
57440 - Kringle-like
56436 - C-type lectin-like | 0 | DIRECT |
48371,49348
48371 - ARM repeat
49348 - Clathrin adaptor appendage domain | 0 | DIRECT |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | DIRECT |
90193,90193
90193 - Notch domain
90193 - Notch domain | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
48452,81901
48452 - TPR-like
81901 - HCP-like | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
52540,50729
52540 - P-loop containing nucleoside triphosphate hydrolases
50729 - PH domain-like | 0 | DIRECT |
47473,57610
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0.03372 | INHERITED FROM: bis(4-hydroxyphenyl)sulfone |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.04837 | INHERITED FROM: Dinitrochlorobenzene || isomethyleugenol || Dihydroxyphenylalanine || ortho-Aminobenzoates || Chlorodiphenyl (54% Chlorine) || dibenzo(a,l)pyrene || Naphthalenesulfonates || Fenamates || 2-allylphenol || 4-propylphenol || Aminobenzoates || Catecholamines || Chlorobenzenes || cumene hydroperoxide || Nitrobenzenes || Cysteinyldopa || Dinitrobenzenes |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.1099 | INHERITED FROM: tanshinone |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.1377 | INHERITED FROM: hydroquinone || 3,3',4,5'-tetrahydroxystilbene || Doxycycline || Chloramphenicol || RTKI cpd || Phloroglucinol || bis(4-hydroxycinnamoyl)methane || demethoxycurcumin || Benzophenones || Anthracenes || Silybin || Hydroquinones || Fenofibrate || Benzene || Tetracyclines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Simvastatin || Benzylidene Compounds || Flavonolignans || Benzenesulfonates || Chlorobenzenes || Catechols || Lovastatin || Fibric Acids || Phenylurea Compounds || Nitrobenzenes || Toluene || Tyrphostins || pyrazolanthrone || Diarylheptanoids |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.1377 | INHERITED FROM: Polyphenols || Parabens || 3,4,5,4'-tetramethoxystilbene || Stilbestrols || Biphenyl Compounds || Aspirin || 2,2',4,4'-tetrabromodiphenyl ether || Benzophenones || aloe emodin || Fenofibrate || Stilbenes || Benzylidene Compounds || butylphen || Catechols || Hydroxybenzoates || Polybrominated Biphenyls || Fibric Acids || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Diarylheptanoids || 5-OH-BDE-47 |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.1541 | INHERITED FROM: Doxycycline || Chloramphenicol || Tetracycline || Phloroglucinol || Anthracenes || Tetracyclines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Simvastatin || Lovastatin || Nitrobenzenes || pyrazolanthrone |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.1627 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.1627 | INHERITED FROM: Pyrenes || Doxorubicin || Daunorubicin || Benzopyrenes |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.2087 | INHERITED FROM: 6-OH-BDE-47 || Catecholamines |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.2118 | INHERITED FROM: Benzamides |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.2149 | INHERITED FROM: Dinitrochlorobenzene || Vitamin K || Sertraline || 1-Naphthylamine || Vitamin K 3 || Anthracenes || Fenofibrate || Chloromercuribenzoates || Benzoates || Chlorobenzenes || Catechols || 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene || Hydroxybenzoates || Nitrobenzenes || Dinitrobenzenes |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.2215 | INHERITED FROM: Benzopyrenes |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.2377 | INHERITED FROM: Parabens || AGN 194204 || labedipinedilol A || Biphenyl Compounds || Sulindac || Phenanthrenes || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || tylophorine || Aspirin || Resveratrol || riccardin D || Anthracenes || Silybin || triptolide || gingerol || acteoside || Indenes || 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid || Stilbenes || 3,5,3',4',5'-pentamethoxystilbene || LG 100268 || Flavonolignans || Hydroxybenzoates || bis(4-hydroxyphenyl)sulfone || Nitrobenzenes || 5-OH-BDE-47 |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.2391 | INHERITED FROM: puag-haad || Curcumin || Diarylheptanoids |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0.2391 | INHERITED FROM: 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0.2589 | INHERITED FROM: resorcinol |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0.2673 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.2969 | INHERITED FROM: 2-Naphthylamine |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.2969 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.3298 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0.3298 | INHERITED FROM: Naphthalenes || Sertraline || 1-Naphthylamine || Chloromercuribenzoates |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0.3298 | INHERITED FROM: Rosuvastatin Calcium || Phenolphthaleins || Fluorobenzenes || Sulfobromophthalein |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.367 | INHERITED FROM: Vitamin K || Vitamin K 3 |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.4075 | INHERITED FROM: 6-OH-BDE-47 || Naphthalenes || Stilbenes || UF010 compound || 5-OH-BDE-47 |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0.4075 | INHERITED FROM: Sulindac || Aspirin || Indenes || Stilbenes || Tamoxifen || Simvastatin || Benzylidene Compounds || Nitrobenzenes |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0.4075 | INHERITED FROM: Aspirin |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0.4532 | INHERITED FROM: afimoxifene || Simvastatin || Lovastatin |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4947 | INHERITED FROM: Triclosan || ML 7 || napabucasin || Benzoates |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.5013 | INHERITED FROM: Masoprocol || Polyphenols || Tetrahydronaphthalenes || Lignans || Stilbestrols || Sulindac || Resveratrol || Mitoxantrone || Etoposide || Hexachlorobenzene || Podophyllotoxin || Anthracenes || Indenes || Stilbenes || Curcumin || Benzylidene Compounds || sulindac sulfide || Chlorobenzenes || Catechols || Phenylurea Compounds || Benzyl Compounds || Tyrphostins || Diarylheptanoids || Epirubicin |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0.5013 | INHERITED FROM: Dibenzocycloheptenes || Benzocycloheptenes || Dizocilpine Maleate |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.5013 | INHERITED FROM: Masoprocol || Polyphenols || Tetrahydronaphthalenes || Lignans || Stilbestrols || Sulindac || Resveratrol || Mitoxantrone || Etoposide || Hexachlorobenzene || Podophyllotoxin || Anthracenes || Indenes || Stilbenes || Curcumin || Benzylidene Compounds || sulindac sulfide || Chlorobenzenes || Catechols || Phenylurea Compounds || Benzyl Compounds || Tyrphostins || Diarylheptanoids || Epirubicin |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0.5013 | INHERITED FROM: Aspirin || Salicylates |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0.5569 | INHERITED FROM: tamibarotene |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0.5581 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Dihydroxydihydrobenzopyrenes |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.6197 | INHERITED FROM: benzo(e)pyrene || Benzopyrenes |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0.6197 | INHERITED FROM: Mercuribenzoates || Chlorobenzoates || Chloromercuribenzoates |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.6363 | INHERITED FROM: 2-xylene || ethylbenzene |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0.6493 | INHERITED FROM: ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.6806 | INHERITED FROM: Biphenyl Compounds || Naphthalenes || Phenanthrenes || N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide || Aspirin || Resveratrol || Benzophenones || Anthracenes || Polychlorinated Biphenyls || Norepinephrine || gingerol || Stilbenes || Tamoxifen || Curcumin || Simvastatin || Benzylidene Compounds || Catecholamines || Benzenesulfonates || Propranolol || Chlorobenzenes || Lovastatin || Isoproterenol || Hydroxybenzoates || Fibric Acids || Phenylurea Compounds || Nitrobenzenes || Diarylheptanoids || Humic Substances |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.6882 | INHERITED FROM: Lignans || Curcumin || Catechols || Benzyl Compounds || Diarylheptanoids |
46579,64593
46579 - Prefoldin
64593 - Intermediate filament protein, coiled coil region | 0.7229 | INHERITED FROM: Sulindac || ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid || Indenes || sulindac sulfide || Bexarotene |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.8213 | INHERITED FROM: Loratadine || tetrabromobisphenol A || Dibenzocycloheptenes || Terfenadine || Benzocycloheptenes || Zeranol || Metaproterenol || 4'-methoxy-1-naphthylfenoterol || Cyproheptadine || Etoposide || Benz(a)Anthracenes || Daunorubicin || Fluorenes || fexofenadine || Anthracyclines || 2-Acetylaminofluorene || Flavonolignans || Catecholamines || zafirlukast || Catechols || Cresols || Isoproterenol || Phenylurea Compounds || Pravastatin || Imatinib Mesylate || Bezafibrate || Benzyl Compounds || zearalenol || Epirubicin |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.8285 | INHERITED FROM: entinostat || Tetrahydronaphthalenes || Minocycline || Naphthalenes || Tetracyclines || tamibarotene |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.8731 | INHERITED FROM: Triclosan |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.8749 | INHERITED FROM: Benzene || Simvastatin |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.8936 | INHERITED FROM: 2,4,3',5'-tetramethoxystilbene || resorcinol || dibenzo(a,l)pyrene || 3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.8958 | INHERITED FROM: Pyrenes || 3,3',4,5'-tetrahydroxystilbene || Polyphenols || Biphenyl Compounds || 4,4'-hexafluorisopropylidene diphenol || Polychlorinated Biphenyls || Fluorenes || Stilbenes || Benzocaine || Benzopyrenes || Aminobenzoates || Catecholamines || Catechols || Isoproterenol || Hydroxybenzoates || Fibric Acids || butamben || Diarylheptanoids |
47986,52540
47986 - DEATH domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.9369 | INHERITED FROM: benzo(e)pyrene |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.9492 | INHERITED FROM: dibenzo(a,l)pyrene |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.9579 | INHERITED FROM: para-Aminobenzoates || 4,4'-hexafluorisopropylidene diphenol || Benzocaine || Aminobenzoates || Catechols || Hydroxybenzoates || butamben |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0.9657 | INHERITED FROM: tamibarotene |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.9977 | INHERITED FROM: honokiol || Sorafenib || tamibarotene || Imatinib Mesylate |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 1 | INHERITED FROM: honokiol || Aspirin || Stilbenes || Benzylidene Compounds || tamibarotene || Hydroxybenzoates || Imatinib Mesylate |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: resorcinol |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Benzocycloheptenes |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 1 | INHERITED FROM: ortho-Aminobenzoates || Flufenamic Acid || Fenamates || Niflumic Acid || Mefenamic Acid || Aminobenzoates |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 1 | INHERITED FROM: tetrabromobisphenol A || 2,4,2',4'-tetrachlorobiphenyl || N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline || 4-nonylphenol || 2,5,2',5'-tetrachlorobiphenyl || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || PCB 180 || 2,2',3,5',6-pentachlorobiphenyl || 2,4,4'-trichlorobiphenyl || Propofol || benzamide || Polybrominated Biphenyls || 4-octylphenol || 3,5-dibromo-2-(2,4-dibromophenoxy)phenol || Toluene |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
54928,90209
54928 - RNA-binding domain, RBD
90209 - Ran binding protein zinc finger-like | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
47353,109640
47353 - Retrovirus capsid dimerization domain-like
109640 - KRAB domain (Kruppel-associated box) | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | Direct |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | Direct |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | Direct |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
54416,54416
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | Direct |
102848,54236
102848 - NSFL1 (p97 ATPase) cofactor p47, SEP domain
54236 - Ubiquitin-like | 0 | Direct |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
141072,141072
141072 - CalX-like
141072 - CalX-like | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
48670,48097
48670 - Transducin (heterotrimeric G protein), gamma chain
48097 - Regulator of G-protein signaling, RGS | 0 | Direct |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | Direct |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
48452,48371
48452 - TPR-like
48371 - ARM repeat | 0 | Direct |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | Direct |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | Direct |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | Direct |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
48065,103657
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like | 0 | Direct |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
53300,69179
53300 - vWA-like
69179 - Integrin domains | 0 | Direct |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | Direct |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
103657,48350
103657 - BAR/IMD domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
100895,50494
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | Direct |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
48371,101447
48371 - ARM repeat
101447 - Formin homology 2 domain (FH2 domain) | 0 | Direct |
57581,57581
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | Direct |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | Direct |
81837,50978
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | Direct |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
57196,56496
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | Direct |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
57196,69687
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
54695,54695
54695 - POZ domain
54695 - POZ domain | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
47113,-7
47113 - Histone-fold
-7 - CATH | 0 | Direct |
49410,50242
49410 - Alpha-macroglobulin receptor domain
50242 - TIMP-like | 0 | Direct |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | Direct |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,46785
50729 - PH domain-like
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
100895,48726
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | Direct |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | Direct |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49695,50370
49695 - gamma-Crystallin-like
50370 - Ricin B-like lectins | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
56496,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
54416,49998
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
50104,50249
50104 - Translation proteins SH3-like domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | Direct |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
63763,57903
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
49299,49299
49299 - PKD domain
49299 - PKD domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | Direct |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | Direct |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | Direct |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | Direct |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | Direct |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | Direct |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
81901,81901
81901 - HCP-like
81901 - HCP-like | 0 | Direct |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
47576,140612
47576 - Calponin-homology domain, CH-domain
140612 - EB1 dimerisation domain-like | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
51905,47576
51905 - FAD/NAD(P)-binding domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | Direct |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | Direct |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | Direct |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | Direct |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | Direct |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | Direct |
48452,46785
48452 - TPR-like
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47862,47862
47862 - Saposin
47862 - Saposin | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
55186,55681
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
47576,143575
47576 - Calponin-homology domain, CH-domain
143575 - GAS2 domain-like | 0 | Direct |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | Direct |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | Direct |
50370,57440
50370 - Ricin B-like lectins
57440 - Kringle-like | 0 | Direct |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
57440,56436
57440 - Kringle-like
56436 - C-type lectin-like | 0 | Direct |
48371,49348
48371 - ARM repeat
49348 - Clathrin adaptor appendage domain | 0 | Direct |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | Direct |
90193,90193
90193 - Notch domain
90193 - Notch domain | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
48452,81901
48452 - TPR-like
81901 - HCP-like | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
52540,50729
52540 - P-loop containing nucleoside triphosphate hydrolases
50729 - PH domain-like | 0 | Direct |
47473,57610
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | Direct |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0.03372 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.04837 | Inherited |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.1099 | Inherited |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.1377 | Inherited |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.1377 | Inherited |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.1541 | Inherited |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.1627 | Inherited |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.1627 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.2087 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.2118 | Inherited |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.2149 | Inherited |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.2215 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.2377 | Inherited |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.2391 | Inherited |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0.2391 | Inherited |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0.2589 | Inherited |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0.2673 | Inherited |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.2969 | Inherited |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.2969 | Inherited |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.3298 | Inherited |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0.3298 | Inherited |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0.3298 | Inherited |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.367 | Inherited |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.4075 | Inherited |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0.4075 | Inherited |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0.4075 | Inherited |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0.4532 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4947 | Inherited |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.5013 | Inherited |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0.5013 | Inherited |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.5013 | Inherited |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0.5013 | Inherited |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0.5569 | Inherited |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0.5581 | Inherited |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.6197 | Inherited |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0.6197 | Inherited |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.6363 | Inherited |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0.6493 | Inherited |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.6806 | Inherited |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.6882 | Inherited |
46579,64593
46579 - Prefoldin
64593 - Intermediate filament protein, coiled coil region | 0.7229 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.8213 | Inherited |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.8285 | Inherited |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.8731 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.8749 | Inherited |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.8936 | Inherited |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.8958 | Inherited |
47986,52540
47986 - DEATH domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.9369 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.9492 | Inherited |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.9579 | Inherited |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0.9657 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.9977 | Inherited |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 1 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 1 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50370,57440,56436
50370 - Ricin B-like lectins
57440 - Kringle-like
56436 - C-type lectin-like | 0 | DIRECT |
54416,54416,49998
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
57184,100895,48726
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | DIRECT |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
100895,47473,57610
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
49899,57196,56496
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
49299,49299,49299
49299 - PKD domain
49299 - PKD domain
49299 - PKD domain | 0 | DIRECT |
50978,50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
55186,55681,52954
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
49854,57535,49854
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
63763,57903,47370
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
48065,50729,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
47473,47473,57850
47473 - EF-hand
47473 - EF-hand
57850 - RING/U-box | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
50729,81837,50978
50729 - PH domain-like
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | DIRECT |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
57184,100895,50494
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | DIRECT |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
56496,49899,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
141072,141072,141072
141072 - CalX-like
141072 - CalX-like
141072 - CalX-like | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
81271,55186,55681
81271 - TGS-like
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
49785,49899,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
57184,57581,57184
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
50729,57863,48403
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
100895,50494,50156
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | DIRECT |
57196,56496,49899
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
57581,57184,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57440,56436,56436
57440 - Kringle-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57184,57581,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48065,103657,50044
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
82185,82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
57184,57184,57581
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
81901,48452,48452
81901 - HCP-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.1541 | INHERITED FROM: tanshinone |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.192 | INHERITED FROM: hydroquinone || Doxycycline || Chloramphenicol || Tetracycline || Phloroglucinol || Anthracenes || Tetracyclines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Simvastatin || Catechols || Lovastatin || Nitrobenzenes || pyrazolanthrone |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.2215 | INHERITED FROM: Benzopyrenes |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.3298 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.3609 | INHERITED FROM: 1-Naphthylisothiocyanate |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.4075 | INHERITED FROM: 2,3,5-(triglutathion-S-yl)hydroquinone || Hydroquinones |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0.5013 | INHERITED FROM: Aspirin || Salicylates |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.5013 | INHERITED FROM: Masoprocol || Polyphenols || Tetrahydronaphthalenes || Lignans || Stilbestrols || Sulindac || Resveratrol || Mitoxantrone || Etoposide || Hexachlorobenzene || Podophyllotoxin || Anthracenes || Indenes || Stilbenes || Curcumin || Benzylidene Compounds || sulindac sulfide || Chlorobenzenes || Catechols || Phenylurea Compounds || Benzyl Compounds || Tyrphostins || Diarylheptanoids || Epirubicin |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.5013 | INHERITED FROM: Biphenyl Compounds || Aspirin || Salicylates || Tamoxifen || Benzene || Curcumin || Simvastatin || Hydroxybenzoates || Fibric Acids || 3,4,5,3',4'-pentachlorobiphenyl || Diarylheptanoids || Humic Substances |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0.5581 | INHERITED FROM: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide || Dihydroxydihydrobenzopyrenes |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.7523 | INHERITED FROM: Benzopyrenes |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.9646 | INHERITED FROM: dibenzo(a,l)pyrene |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0.9657 | INHERITED FROM: tamibarotene |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.9657 | INHERITED FROM: para-Aminobenzoates || 4,4'-hexafluorisopropylidene diphenol || Benzocaine || Aminobenzoates || Catechols || Hydroxybenzoates || butamben || Diarylheptanoids |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9711 | INHERITED FROM: 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: resorcinol |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 1 | INHERITED FROM: honokiol || Sorafenib || Stilbenes || tamibarotene || Hydroxybenzoates || Imatinib Mesylate |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50370,57440,56436
50370 - Ricin B-like lectins
57440 - Kringle-like
56436 - C-type lectin-like | 0 | Direct |
54416,54416,49998
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
57184,100895,48726
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | Direct |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
100895,47473,57610
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | Direct |
49899,57196,56496
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
49299,49299,49299
49299 - PKD domain
49299 - PKD domain
49299 - PKD domain | 0 | Direct |
50978,50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | Direct |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
55186,55681,52954
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
49854,57535,49854
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
63763,57903,47370
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
48065,50729,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
47473,47473,57850
47473 - EF-hand
47473 - EF-hand
57850 - RING/U-box | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
50729,81837,50978
50729 - PH domain-like
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | Direct |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
57184,100895,50494
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | Direct |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
56496,49899,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
141072,141072,141072
141072 - CalX-like
141072 - CalX-like
141072 - CalX-like | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
81271,55186,55681
81271 - TGS-like
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
49785,49899,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
57184,57581,57184
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
50729,57863,48403
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
100895,50494,50156
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | Direct |
57196,56496,49899
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | Direct |
57581,57184,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57440,56436,56436
57440 - Kringle-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57184,57581,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48065,103657,50044
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
82185,82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
57184,57184,57581
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
81901,48452,48452
81901 - HCP-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.1541 | Inherited |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.192 | Inherited |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.2215 | Inherited |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.3298 | Inherited |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.3609 | Inherited |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.4075 | Inherited |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0.5013 | Inherited |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.5013 | Inherited |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.5013 | Inherited |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0.5581 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.7523 | Inherited |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.9646 | Inherited |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0.9657 | Inherited |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.9657 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9711 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Hydrocarbons, Aromatic
