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CTD Chemicals (CC): Heterocyclic Compounds, Fused-Ring 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| GLA-domain | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Lipoxigenase | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| FKBP-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Probable bacterial effector-binding domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Pentapeptide repeat-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Uteroglobin-like | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Triple coiled coil domain of C-type lectins | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Hermes dimerisation domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.01007 | INHERITED FROM: Benzothiepins || pomiferin || Dronedarone || osajin || Purine Nucleotides || tegaserod || quinoxyfen || Reserpine || Benzoxazines || Aminoacridines || kaempferol || Ro 41-5253 || Flavonoids || Nebivolol || ZK 216348 || Isoquinolines || biochanin A || Benomyl || pitavastatin || Emetine || galaxolide || 2-acetylphenothiazine || Adenine Nucleotides || irilone || Quinolines || daidzein || Kaempferols || Silybin || Acridines || Proflavine || chlormidazole || Heterocyclic Compounds, 4 or More Rings || norathyriol || flavone || icaritin || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || 3-methylquercetin || Staurosporine |
| ARM repeat | 0.01458 | INHERITED FROM: N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.01602 | INHERITED FROM: N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || aflatoxin B2 |
| Protein kinase-like (PK-like) | 0.02653 | INHERITED FROM: Semaxinib || quercetin 4'-O-glucopyranoside || Tubercidin || tylophorine || baohuoside I || orantinib || indole-5-carboxamide || Indolizines || Cantharidin || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || Cyclic GMP || Benzopyrans || Folfox protocol || Coumarins || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || Quinazolines || Pyocyanine || Phenazines || dracorhodin || SU 6656 || APS-2-79 || 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbo || Heterocyclic Compounds, 3-Ring || Naphthyridines || Anthocyanins || pifithrin || 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide || 103D5R || Flavones || 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine || dihydromyricetin || Adenosine Diphosphate || Xanthenes || Isoindoles || Benzodioxoles || Indoles || bisindolylmaleimide || esculetin || Isoquinolines || staurosporine aglycone || Chromones || didymin || GSK 1363089 || rottlerin || Quinoxalines || Tocopherols || Carbazoles || deguelin || bisindolylmaleimide I || WHI P154 || fascaplysine || Indazoles || copper-1,10-phenanthroline || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || Quinolines || Sunitinib || dictamnine || 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone || 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione || coptisine || 1',2'-dihydrorotenone || dehydroglyasperin C || alvocidib || Benzimidazoles || napabucasin || aflatoxin B2 || Sterigmatocystin || Ochratoxins || Win 55212-2 || Benzothiazoles || 5-iodotubercidin || 6,7-dimethoxy-3-phenylquinoxaline || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Polyphenols || Staurosporine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| SMAD/FHA domain | 0.04338 | INHERITED FROM: casticin || fludarabine || osthol || Cytochalasins || galangin || Vidarabine || Cytochalasin D |
| PH domain-like | 0.0526 | INHERITED FROM: Benzopyrans || Catechin || (N)-methanocarba-2MeSADP || Indoles || aflatoxin B2 |
| NAD(P)-binding Rossmann-fold domains | 0.05883 | INHERITED FROM: Oxcarbazepine || Purine Nucleotides || NAD || Isatin || Adenine Nucleotides || NADP || Purines |
| PLP-dependent transferases | 0.09244 | INHERITED FROM: Tetrachlorodibenzodioxin |
| Periplasmic binding protein-like I | 0.113 | INHERITED FROM: Citalopram |
| MHC antigen-recognition domain | 0.1207 | INHERITED FROM: beta-Lactams || Benzothiadiazines || Gefitinib || Quinazolines || Ampicillin || Ketorolac || Diltiazem || Cephalosporins || Omeprazole || Quinolines || Penicillin G || Chlorothiazide |
| vWA-like | 0.1208 | INHERITED FROM: 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| P-loop containing nucleoside triphosphate hydrolases | 0.1537 | INHERITED FROM: Vinca Alkaloids || Thioxanthenes || calcein AM || bisbenzimide ethoxide trihydrochloride || fluorexon || pitavastatin || verlukast || Elacridar || 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)a || Phosphoadenosine Phosphosulfate || TAK-875 || Tolvaptan || Coumestrol || AC 93253 |
| PDZ domain-like | 0.1557 | INHERITED FROM: aflatoxin B2 || Heterocyclic Compounds, 2-Ring |
| Cadherin-like | 0.1573 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
| SH2 domain | 0.1653 | INHERITED FROM: 4'-methoxy licoflavanone || Heterocyclic Compounds, 3-Ring || alpinumisoflavone || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine || isoquercitrin || WP1066 || Polyphenols || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside |
| Alkaline phosphatase-like | 0.1776 | INHERITED FROM: PP242 |
| Acetyl-CoA synthetase-like | 0.1894 | INHERITED FROM: Tetrachlorodibenzodioxin |
| SH3-domain | 0.1979 | INHERITED FROM: aflatoxin B2 |
| EGF/Laminin | 0.1979 | INHERITED FROM: Tetrachlorodibenzodioxin || Heterocyclic Compounds, 3-Ring || GSK1210151A || Quinoxalines || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || aflatoxin B2 |
| E set domains | 0.2003 | INHERITED FROM: scoparone || piperine || Harmala Alkaloids || Benzoxazoles || Calcimycin || Carbolines |
| Fibronectin type III | 0.2393 | INHERITED FROM: Panobinostat || aflatoxin B2 |
| FAD/NAD(P)-binding domain | 0.2515 | INHERITED FROM: Purine Nucleosides || Benzydamine || Indazoles || senkirkine || Pyrrolizidine Alkaloids |
| Leucine zipper domain | 0.2746 | INHERITED FROM: Tetrachlorodibenzodioxin || Pteridines || Aminopterin || Quinazolines || Vinca Alkaloids || quinomethionate || Heterocyclic Compounds, 3-Ring || Hemin || Penicillins || Citrinin || piperine || BIX 02189 || Phenanthrolines || Benzofurans || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Flavonoids || Phthalimides || Isoindoles || Benzodioxoles || Isoquinolines || rottlerin || sauchinone || Quercetin || Quinoxalines || Quinolines || Tetrapyrroles || alpha-Tocopherol || Cyclic AMP || Penicillin G || fisetin || Heterocyclic Compounds, 4 or More Rings || Uric Acid || Indole Alkaloids || Ochratoxins || 4-Quinolones || NSC668394 || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbamazepine |
| TNF receptor-like | 0.2753 | INHERITED FROM: Genistein || Pteridines || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Flavones || motexafin gadolinium || fludarabine || Pentoxifylline || Benzophenanthridines || Isoindoles || Quinolones || osthol || Aripiprazole || sanguinarine || Quinolines || Theobromine || licochalcone A || Vidarabine || Vemurafenib || Polyphenols |
| Growth factor receptor domain | 0.2784 | INHERITED FROM: Pteridines || Folfox protocol || Quinazolines || Troglitazone || Heterocyclic Compounds, 3-Ring || Flavones || baicalin || Formyltetrahydrofolates || napabucasin || CMF regimen |
| PX domain | 0.2825 | INHERITED FROM: Go 6976 |
| Cyclin-like | 0.2882 | INHERITED FROM: 7,3'-dihydroxy-4'-methoxyisoflavone || tylophorine || Indolizines || Flavanones || Quinazolines || abemaciclib || THRX 165724 || scriptaid || Trabectedin || Aminoacridines || MK-886 || Citrinin || fludarabine || Ro 41-5253 || Phenanthridines || rottlerin || Quinoxalines || Tocopherols || Chromans || Indazoles || Quinolines || cryptolepine || Silybin || Roscovitine || Acridines || CP-654577 || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || 1',2'-dihydrorotenone || alvocidib || Hypoxanthines || Guanine || 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-d || Benzimidazoles || Vemurafenib || Ochratoxins || Benzothiazoles || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || AC 93253 || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Chaperone J-domain | 0.2906 | INHERITED FROM: motexafin gadolinium || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Dibenzazepines || Carbamazepine |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.2948 | INHERITED FROM: S-Adenosylmethionine || procyanidin B2 |
| Nuclear receptor ligand-binding domain | 0.2993 | INHERITED FROM: Tetrachlorodibenzodioxin || Benzothiepins || pomiferin || Fluvastatin || Coumarins || Dronedarone || osajin || Quinazolines || Purine Nucleotides || puerarin || tegaserod || quinoxyfen || Reserpine || Heterocyclic Compounds, 3-Ring || 8-prenylnaringenin || Yohimbine || Furocoumarins || Benzoxazines || Aminoacridines || MK-886 || Flavones || Berberine || Benzofurans || kaempferol || Ro 41-5253 || Melatonin || Flavonoids || Nebivolol || ZK 216348 || Benzoflavones || Isoquinolines || Lansoprazole || biochanin A || Benomyl || pitavastatin || Emetine || galaxolide || Quercetin || Quinoxalines || 2-acetylphenothiazine || Tocopherols || Adenine Nucleotides || Carbazoles || Chromans || Phenothiazines || irilone || Quinolines || daidzein || Kaempferols || Silybin || Acridines || Rifamycins || Proflavine || Purines || chlormidazole || Heterocyclic Compounds, 4 or More Rings || norathyriol || flavone || Benzimidazoles || chrysin || icaritin || 3,3'-diindolylmethane || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tryptamines || 3-methylquercetin || Staurosporine |
| SET domain | 0.3262 | INHERITED FROM: Benzylisoquinolines || Berberine || Isoquinolines || Berberine Alkaloids |
| Frizzled cysteine-rich domain | 0.35 | INHERITED FROM: Panobinostat || deguelin || 1-Methyl-3-isobutylxanthine || Carbamazepine |
| Histone-fold | 0.41 | INHERITED FROM: Thioxanthenes || Xanthones || Folic Acid || Benzylisoquinolines || Berberine || OTX015 || Xanthenes || Isoquinolines || Heterocyclic Compounds, 4 or More Rings || Berberine Alkaloids || Lucanthone || Coumestrol |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.4585 | INHERITED FROM: naringenin chalcone || 4-Hydroxycoumarins || Tetrachlorodibenzodioxin || Phloretin || 7,3'-dihydroxy-4'-methoxyisoflavone || grepafloxacin || Benzodiazepines || bergamottin || auriculasin || Ofloxacin || Flavanones || Benzodiazepinones || puerarin || glabridin || Indoprofen || lorcaserin || Moxifloxacin || Furocoumarins || Indoleacetic Acids || Fluoroquinolones || amentoflavone || kaempferol || Umbelliferones || 2',5'-dihydroxychalcone || 2',4'-dihydroxychalcone || Benzoflavones || MK-0524 || biochanin A || Oxazepam || Morphine || morin || Omeprazole || 7-hydroxy-4-(trifluoromethyl)coumarin || daidzein || Hymecromone || Kaempferols || mangiferin || Scopoletin || Chalcones || Silybin || 7-hydroxy-4-trifluoromethylcoumarin || Equol || licochalcone A || sitafloxacin || Biflavonoids || galangin || 2-Pyridinylmethylsulfinylbenzimidazoles || formononetin || fisetin || Benzimidazoles || chrysin || Warfarin || Etodolac || Apigenin || Morphinans || Flavonolignans || naringenin || Pyrrolizidine Alkaloids || Morphine Derivatives || beta-Naphthoflavone |
| DEATH domain | 0.4598 | INHERITED FROM: tylophorine || Genistein || Indolizines || Cantharidin || polyphenon E || auriculasin || gardenin B || Flavanones || Pteridines || quinoline-val-asp(OMe)-CH2-OPH || Dactinomycin || Quinazolines || Benzodiazepinones || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || dracorhodin || Purine Nucleosides || KN 62 || casticin || abexinostat || Indoleacetic Acids || Benzoxazines || Flavones || EKB 569 || fludarabine || Benzofurans || Pentoxifylline || Phenanthridines || Flavonoids || Umbelliferones || Benzophenanthridines || Phthalimides || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || Isoindoles || esculetin || Isoquinolines || Adenosine || Bendamustine Hydrochloride || Riluzole || Quinolones || osthol || Quercetin || Allopurinol || sanguinarine || echimidine || Tocopherols || morin || Pterins || Carbazoles || indole-3-carbinol || Quinolines || Tetrapyrroles || Theobromine || Chalcones || 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid || idelalisib || Vidarabine || alvocidib || Guanine || fisetin || Heterocyclic Compounds, 4 or More Rings || Vemurafenib || CFM 1 || Cladribine || Win 55212-2 || Porphyrins || Benzothiazoles || Calcimycin || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide || Apigenin || Polyphenols || SRT2183 || Staurosporine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| FnI-like domain | 0.4672 | INHERITED FROM: Pteridines || GSK1210151A || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Adenine Nucleotides || Tetrapyrroles || Quinazolinones || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| Terpenoid cyclases/Protein prenyltransferases | 0.4696 | INHERITED FROM: Benzodiazepines || Olanzapine |
| Fibrinogen C-terminal domain-like | 0.4804 | INHERITED FROM: Adenosine Diphosphate |
| Translation proteins SH3-like domain | 0.4979 | INHERITED FROM: Vitamin E |
| RNA-binding domain, RBD | 0.5428 | INHERITED FROM: PP242 || Vinca Alkaloids || Vitamin E |
| SNARE fusion complex | 0.55 | INHERITED FROM: Heroin || Morphinans || Morphine Derivatives |
| Toll/Interleukin receptor TIR domain | 0.5649 | INHERITED FROM: 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || Aripiprazole || Quinolines || Erlotinib Hydrochloride || chrysin || E804 bisindole |
| Kringle-like | 0.5649 | INHERITED FROM: baicalein || Flavanones || Dactinomycin || Quinazolines || 3-hydroxyflavone || Benzoxazines || GSK1210151A || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || kaempferol || Benzophenanthridines || Benomyl || Tetrapyrroles || Chalcones || Silybin || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Chlorpromazine || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || chrysin || Porphyrins || 3,3'-diindolylmethane || carbendazim || Apigenin || Flavonolignans |
| HSP20-like chaperones | 0.5805 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Adenosine Triphosphate |
| BRCT domain | 0.5972 | INHERITED FROM: fludarabine |
| "Winged helix" DNA-binding domain | 0.5998 | INHERITED FROM: Harmine || Harmala Alkaloids |
| beta-beta-alpha zinc fingers | 0.6033 | INHERITED FROM: GSK-J4 || Aflatoxin M1 || Benzazepines || pomalidomide |
| HMG-box | 0.6038 | INHERITED FROM: Polyphenols |
| Serpins | 0.6178 | INHERITED FROM: Tetrachlorodibenzodioxin || periodate-oxidized adenosine || Rifampin || Benzoflavones || Polychlorinated Dibenzodioxins |
| Hemopexin-like domain | 0.6235 | INHERITED FROM: Benzodiazepines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || Quinazolines || Purine Nucleosides || Benzylisoquinolines || Berberine || piperine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Ciprofloxacin || sauchinone || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Tyrphostins || dieckol || deguelin || Tetrapyrroles || varespladib methyl || Silybin || chrysin || Porphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Cystatin/monellin | 0.6235 | INHERITED FROM: Lucanthone |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.6269 | INHERITED FROM: Troglitazone || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Quercetin || Chromans || Tetrapyrroles || usnic acid || Heterocyclic Compounds, 4 or More Rings || Benzimidazoles || Porphyrins |
| MFS general substrate transporter | 0.631 | INHERITED FROM: Phloretin || Serotonin || pseudoisocyanine || Quinine || 6-carboxyfluorescein || Heterocyclic Compounds, 3-Ring || 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine || Ethidium || Mirtazapine || Rifampin || Cephalexin || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Formyltetrahydrofolates || 7-(deoxyadenosin-N(6)-yl)aristolactam I || Quinidine || Rifamycins || Ceftibuten || Heterocyclic Compounds, 4 or More Rings || Uric Acid || 2-amino-3,4-dimethylimidazo(4,5-f)quinoline || Cytochalasin B || Carbolines |
| Metalloproteases ("zincins"), catalytic domain | 0.6598 | INHERITED FROM: manganese(III)-tetrakis(4-benzoic acid)porphyrin || Benomyl || sauchinone || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || dieckol || varespladib methyl || benazepril || RTKI cpd |
| E2F-DP heterodimerization region | 0.6633 | INHERITED FROM: Coumarins || Ochratoxins |
| FAD-linked reductases, C-terminal domain | 0.665 | INHERITED FROM: periodate-oxidized adenosine |
| p53-like transcription factors | 0.6947 | INHERITED FROM: Flavanones || scoparone || Dactinomycin || Vinca Alkaloids || Benzodiazepinones || 4'-methoxy licoflavanone || Anthocyanins || Ergolines || Ellagic Acid || Luteolin || Flavones || piperine || alpinumisoflavone || isoquercitrin || Umbelliferones || Isoindoles || Benzodioxoles || esculetin || Harmala Alkaloids || Cytochalasins || Morphine || Carbazoles || Pergolide || alpha-naphthoflavone || bisindolylmaleimide I || Dicumarol || Kaempferols || fisetin || chrysin || Benzoxazoles || Resveratrol || Benzothiazoles || Calcimycin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Apigenin || myricetin || Polyphenols || SRT2183 || Carbolines || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Staurosporine |
| NAD(P)-linked oxidoreductase | 0.7014 | INHERITED FROM: beta-Lactams || Oxcarbazepine || Benzodiazepines || 1,10-phenanthroline || Flavanones || Purine Nucleotides || Benzodiazepinones || Penicillins || Medazepam || Ampicillin || Phenanthrolines || Azathioprine || Umbelliferones || Benzoflavones || Diazepam || Nitrazepam || Benzbromarone || Adenine Nucleotides || NADP || cloxazolam || Penicillin G || Estazolam || Oxyquinoline || Flunitrazepam || Benzothiazoles || NSC668394 || naringenin || beta-Naphthoflavone |
| Carbonic anhydrase | 0.7014 | INHERITED FROM: Benzothiazoles || Ethoxzolamide || Flavonolignans |
| A DNA-binding domain in eukaryotic transcription factors | 0.7205 | INHERITED FROM: Hemin || S-Adenosylmethionine || Tetrapyrroles || Heterocyclic Compounds, 4 or More Rings || Indole Alkaloids |
| PGBD-like | 0.7216 | INHERITED FROM: manganese(III)-tetrakis(4-benzoic acid)porphyrin || Aminopterin || Quinazolines || Xanthones || piperine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Ciprofloxacin || sauchinone || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Quinoxalines || Tyrphostins || dieckol || Carbazoles || deguelin || Tetrapyrroles || varespladib methyl || Silybin || chrysin || Porphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || RTKI cpd || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Caspase-like | 0.7404 | INHERITED FROM: 2-Chloroadenosine || baohuoside I || Mitomycins || Chloroquine || Ellipticines || Benzodiazepines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 3',4'-dimethoxyflavone || 4-chromone || Cantharidin || polyphenon E || auriculasin || gardenin B || Flavanones || Secologanin Tryptamine Alkaloids || Fluvastatin || Pteridines || senecionine || mangostin || quinoline-val-asp(OMe)-CH2-OPH || Dactinomycin || phthalocyanine Pc 4 || 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline || Quinazolines || Benzodiazepinones || dracorhodin || Purine Nucleosides || NMS-873 || cyanidin 3-O-glucoside || Rutin || Xanthones || Naphthyridines || Anthocyanins || 2-hydroxy-3',5,5'-trimethoxychalcone || casticin || abexinostat || pifithrin || Furocoumarins || 6-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone || Indoleacetic Acids || Benzoxazines || Indolequinones || cobaltiprotoporphyrin || Fluoroquinolones || 9-hydroxycanthin-6-one || Aminoacridines || Clofarabine || SCIO-469 || Flavones || Berberine || Benzoxepins || fludarabine || Benzofurans || alpha-viniferin || anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione || 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one || kaempferol || Pentoxifylline || Melatonin || Phenanthridines || Umbelliferones || Benzophenanthridines || Catechin || Phthalimides || dihydromyricetin || Deoxyadenosines || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || Isoindoles || Benzodioxoles || esculetin || Isoquinolines || Adenosine || gambogic acid || Bendamustine Hydrochloride || Riluzole || rottlerin || ellipticine || osthol || Ciprofloxacin || isoangustone A || Quercetin || Morphine || ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate || sanguinarine || echimidine || 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide || Tocopherols || morin || Pterins || Adenine Nucleotides || tetrandrine || Carbazoles || indole-3-carbinol || Chromans || deguelin || copper-1,10-phenanthroline || Quinolines || Adenine || Theobromine || sinularin || Chalcones || xanthohumol || Acridines || Equol || 3-methyladenine || paederosidic acid || idelalisib || Methoxsalen || Flavonols || MK 2206 || SNX 2112 || Vidarabine || alvocidib || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || formononetin || fisetin || Heterocyclic Compounds, 4 or More Rings || zinc protoporphyrin || Benzimidazoles || CFM 1 || 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane || chrysin || Benzoxazoles || Resveratrol || sesamol || p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane || Cladribine || Ochratoxins || Win 55212-2 || Benzothiazoles || Calcimycin || senkirkine || heliotrine || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || 5,6-dichlorobenzimidazole || Etodolac || lonidamine || Tryptamines || Apigenin || quercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside || trovafloxacin || (2)-5,6,7,8,4'-pentamethoxyflavanone || Flavonolignans || myricetin || Polyphenols || Pyrrolizidine Alkaloids || Staurosporine || Morphine Derivatives || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| GroEL equatorial domain-like | 0.7597 | INHERITED FROM: Albendazole |
| Arginase/deacetylase | 0.7597 | INHERITED FROM: Benzothiepins || polyphenon E || Berberine |
| GroEL apical domain-like | 0.7597 | INHERITED FROM: Albendazole |
| Ubiquitin-like | 0.7627 | INHERITED FROM: N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| Polo-box domain | 0.7849 | INHERITED FROM: Genistein || Troglitazone |
| Ribosomal protein S5 domain 2-like | 0.7896 | INHERITED FROM: O(6)-benzylguanine || Guanine || Adenosine Triphosphate |
| cAMP-binding domain-like | 0.7931 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide |
| GroEL-intermediate domain like | 0.7994 | INHERITED FROM: Albendazole |
| PYP-like sensor domain (PAS domain) | 0.8012 | INHERITED FROM: Semaxinib || gallocatechol || 1,10-phenanthroline || 3-hydroxyflavone || Anthocyanins || 2,3,7,8-tetrachlorodibenzofuran || Flavones || kaempferol || Rifampin || Indican || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Omeprazole || Kaempferols || Acridines || Rifamycins || 2,3,4,7,8-pentachlorodibenzofuran || galangin || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Benzimidazoles || 3,3'-diindolylmethane || epicatechin gallate || Polyphenols |
| Cytokine | 0.8012 | INHERITED FROM: Phloretin || usnic acid || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Thioredoxin-like | 0.8125 | INHERITED FROM: Chlorophyllides || desethylamodiaquine || Bile Pigments || captafol || Amodiaquine || Tetrapyrroles || Quinidine || KT 5720 || xanthohumol || Captan || amodiaquine quinoneimine |
| Enolase C-terminal domain-like | 0.8288 | INHERITED FROM: Pteridines || Aminopterin || Pterins |
| Enolase N-terminal domain-like | 0.8288 | INHERITED FROM: Pteridines || Aminopterin || Pterins |
| Mitochondrial carrier | 0.8299 | INHERITED FROM: Adenosine Triphosphate |
| Nucleic acid-binding proteins | 0.837 | INHERITED FROM: Coumarins || Chromans || cryptolepine |
| SNARE-like | 0.8607 | INHERITED FROM: PP242 |
| LDL receptor-like module | 0.8638 | INHERITED FROM: Olanzapine |
| Actin-like ATPase domain | 0.878 | INHERITED FROM: Hemin || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || indirubin-3'-monoxime || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Benzimidazoles |
| Spermadhesin, CUB domain | 0.8823 | INHERITED FROM: Panobinostat |
| TNF-like | 0.8823 | INHERITED FROM: Phenanthridines || Benzophenanthridines || candesartan || Quinolones || Aripiprazole || sanguinarine || Clozapine || Vemurafenib |
| SCOP hierarchy in SUPERFAMILY | 0.8854 | INHERITED FROM: quinoline || PP242 || Caffeine || Xanthenes || Purines || Xanthines |
| Inhibitor of apoptosis (IAP) repeat | 0.8859 | INHERITED FROM: Secologanin Tryptamine Alkaloids || Quinazolines || Purine Nucleosides || Flavones || EKB 569 || Pentoxifylline || Isoquinolines || Adenosine || Bendamustine Hydrochloride || Quinoxalines || morin || Carbazoles || indole-3-carbinol || Quinolines || Theobromine || Vinblastine || Chalcones || N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine || alvocidib || Benzimidazoles || Resveratrol || Porphyrins || Polyphenols || evodiamine || Staurosporine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Interleukin 8-like chemokines | 0.9072 | INHERITED FROM: captax || 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline || coralyne || 3'-methoxy-4'-nitroflavone || Dequalinium || Secologanin Tryptamine Alkaloids || Pteridines || Aminopterin || Vinca Alkaloids || Troglitazone || Puromycin || PD168393 || Telmisartan || Rutin || Hesperidin || Quinolinium Compounds || 6,2',4'-trimethoxyflavone || Albendazole || Flavones || Propidium || Phenanthridines || palmatine || 7-bromoindirubin-3'-oxime || Quinolones || Aripiprazole || Emetine || Allopurinol || Pterins || Quinolines || 6-formylindolo(3,2-b)carbazole || Benzimidazoles || Benzoxazoles || E804 bisindole || Calcimycin || Morphinans || Polyphenols || Morphine Derivatives |
| S15/NS1 RNA-binding domain | 0.9085 | INHERITED FROM: Isocoumarins || Ochratoxins |
| Bromodomain | 0.9154 | INHERITED FROM: OTX015 |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.9204 | INHERITED FROM: Vitamin E |
| HLH, helix-loop-helix DNA-binding domain | 0.922 | INHERITED FROM: Genistein || Anthocyanins || 2,3,7,8-tetrachlorodibenzofuran || Rifampin || baicalin || Indican || 2,3,4,7,8-pentachlorodibenzofuran || galangin |
| Voltage-gated potassium channels | 0.9259 | INHERITED FROM: Tetrodotoxin || Astemizole || Mibefradil |
| Sm-like ribonucleoproteins | 0.9289 | INHERITED FROM: PP242 |
| Kazal-type serine protease inhibitors | 0.9359 | INHERITED FROM: naringin |
| Orange domain-like | 0.9436 | INHERITED FROM: baicalein || Flavanones || baicalin |
| (Trans)glycosidases | 0.9676 | INHERITED FROM: PP242 |
| Concanavalin A-like lectins/glucanases | 0.982 | INHERITED FROM: Panobinostat |
| Cysteine proteinases | 0.982 | INHERITED FROM: benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide |
| DBL homology domain (DH-domain) | 0.9887 | INHERITED FROM: aflatoxin B2 |
| Trypsin-like serine proteases | 1 | INHERITED FROM: 4-Hydroxycoumarins || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Warfarin |
| C-type lectin-like | 1 | INHERITED FROM: Nebivolol |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: GSK-J4 || Aflatoxin M1 || Benzazepines |
| Cystine-knot cytokines | 1 | INHERITED FROM: cyanidin || N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Quinazolines || Purine Nucleotides || delphinidin || Anthocyanins || MOPP protocol || GSK1210151A || Ramipril || Isoindoles || Isoquinolines || Adenine Nucleotides || Carbazoles || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || fulvic acid || Heterocyclic Compounds, 4 or More Rings || Benzoxazoles || Calcimycin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Protoporphyrins |
| ADP-ribosylation | 1 | INHERITED FROM: XAV939 || rucaparib || veliparib |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: 6-O-monoacetylmorphine || Heroin || Galantamine || Tacrine || Physostigmine || Morphine Derivatives |
| Snake toxin-like | 1 | INHERITED FROM: rutecarpine |
| L domain-like | 1 | INHERITED FROM: Folfox protocol || CMF regimen |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | INHERITED FROM: Atracurium || Benzodiazepines || Mivacurium || L 663581 || Ro 15-4513 || Benzylisoquinolines || Isoquinolines || Dihydro-beta-Erythroidine || Quinolizines || cisatracurium || cytisine || desformylflustrabromine || Bicuculline || Tubocurarine || bretazenil |
| Insulin-like | 1 | INHERITED FROM: Benzimidazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| HD-domain/PDEase-like | 1 | INHERITED FROM: Purine Nucleotides || NVP ABE171 || Naphthyridines || PF-04254644 || trequinsin || Tetrahydroisoquinolines || Isoquinolines || Quinolines || E 4021 |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: Lurasidone Hydrochloride || 7-hydroxymitragynine || abanoquil || Ketanserin || 7-fluoro-2-oxo-4-(2-(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)ethyl)-1,2-dihydroquinoline-1-aceta || proanthocyanidin || brucine N-oxide || alfuzosin || A 86929 || 7-methyl-6,7,8,9,14,15-hexahydro-5H-benz(d)indolo(2,3-g)azecine || indole || 1,3-dipropyl-8-cyclopentylxanthine || quercitrin || (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) || Idazoxan |
| Nicotinic receptor ligand binding domain-like | 1 | INHERITED FROM: Atracurium || Benzodiazepines || Mivacurium || L 663581 || Ro 15-4513 || Benzylisoquinolines || Isoquinolines || Dihydro-beta-Erythroidine || Quinolizines || cisatracurium || cytisine || desformylflustrabromine || Bicuculline || Tubocurarine || bretazenil |
| 4-helical cytokines | 1 | INHERITED FROM: Phloretin || beta-Lactams || epinastine || Pteridines || Apomorphine || Dactinomycin || Naphthyridines || Hesperidin || Ergolines || 6,2',4'-trimethoxyflavone || Flavones || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || Azathioprine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || kaempferol || Ro 41-5253 || Phthalimides || Isoindoles || Benzodioxoles || Isoquinolines || 7-bromoindirubin-3'-oxime || hesperetin || Ciprofloxacin || Aripiprazole || Cytochalasins || Quinoxalines || Tyrphostins || Adenine Nucleotides || Carbazoles || Quinolines || Tetrapyrroles || Clozapine || Kaempferols || Aporphines || fisetin || 6-formylindolo(3,2-b)carbazole || Benzimidazoles || Benzoxazoles || StemRegenin 1 || E804 bisindole || Calcimycin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Morphinans || Flavonolignans || Polyphenols || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Intermediate filament protein, coiled coil region | 1 | INHERITED FROM: flavone |
| Immunoglobulin | 1 | INHERITED FROM: beta-Lactams || orantinib || Benzothiadiazines || HX 630 || 3,5-di-tert-butylchalcone 4'-carboxylic acid || thieno(2,3-c)isoquinolin-5-one || Ketorolac || Aripiprazole || Cephalosporins || Lenalidomide || gardiquimod |
| Homeodomain-like | 1 | INHERITED FROM: Panobinostat |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| GLA-domain | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| HCP-like | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| BolA-like | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| SIS domain | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| GroES-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| FF domain | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| N-(deoxy)ribosyltransferase-like | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Lipoxigenase | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| AXH domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PUG domain-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| AhpD-like | 0 | Direct |
| LanC-like | 0 | Direct |
| Sema domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| BRK domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| ISP domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Nop domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Metallothionein | 0 | Direct |
| PP2C-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| DNA clamp | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| SRF-like | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| ITPase-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| BSD domain-like | 0 | Direct |
| L30e-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| ACP-like | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| LysM domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Aldolase | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| BEACH domain | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| PKD domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| KA1-like | 0 | Direct |
| FKBP-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| PWI domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| ADC-like | 0 | Direct |
| Probable bacterial effector-binding domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| SNF-like | 0 | Direct |
| GFP-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| RGC domain-like | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Pentein | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Pentapeptide repeat-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Flavoproteins | 0 | Direct |
| DLC | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| STAT | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Connexin43 | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| LigT-like | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Synuclein | 0 | Direct |
| eIF1-like | 0 | Direct |
| Uteroglobin-like | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| TIMP-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| HIT-like | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| L27 domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Integrin domains | 0 | Direct |
| Annexin | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Mss4-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Triple coiled coil domain of C-type lectins | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Hermes dimerisation domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Notch domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| WWE domain | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Plakin repeat | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| PapD-like | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Translational machinery components | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.01007 | Inherited |
| ARM repeat | 0.01458 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.01602 | Inherited |
| Protein kinase-like (PK-like) | 0.02653 | Inherited |
| SMAD/FHA domain | 0.04338 | Inherited |
| PH domain-like | 0.0526 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.05883 | Inherited |
| PLP-dependent transferases | 0.09244 | Inherited |
| Periplasmic binding protein-like I | 0.113 | Inherited |
| MHC antigen-recognition domain | 0.1207 | Inherited |
| vWA-like | 0.1208 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.1537 | Inherited |
| PDZ domain-like | 0.1557 | Inherited |
| Cadherin-like | 0.1573 | Inherited |
| SH2 domain | 0.1653 | Inherited |
| Alkaline phosphatase-like | 0.1776 | Inherited |
| Acetyl-CoA synthetase-like | 0.1894 | Inherited |
| SH3-domain | 0.1979 | Inherited |
| EGF/Laminin | 0.1979 | Inherited |
| E set domains | 0.2003 | Inherited |
| Fibronectin type III | 0.2393 | Inherited |
| FAD/NAD(P)-binding domain | 0.2515 | Inherited |
| Leucine zipper domain | 0.2746 | Inherited |
| TNF receptor-like | 0.2753 | Inherited |
| Growth factor receptor domain | 0.2784 | Inherited |
| PX domain | 0.2825 | Inherited |
| Cyclin-like | 0.2882 | Inherited |
| Chaperone J-domain | 0.2906 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.2948 | Inherited |
| Nuclear receptor ligand-binding domain | 0.2993 | Inherited |
| SET domain | 0.3262 | Inherited |
| Frizzled cysteine-rich domain | 0.35 | Inherited |
| Histone-fold | 0.41 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.4585 | Inherited |
| DEATH domain | 0.4598 | Inherited |
| FnI-like domain | 0.4672 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 0.4696 | Inherited |
| Fibrinogen C-terminal domain-like | 0.4804 | Inherited |
| Translation proteins SH3-like domain | 0.4979 | Inherited |
| RNA-binding domain, RBD | 0.5428 | Inherited |
| SNARE fusion complex | 0.55 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.5649 | Inherited |
| Kringle-like | 0.5649 | Inherited |
| HSP20-like chaperones | 0.5805 | Inherited |
| BRCT domain | 0.5972 | Inherited |
| "Winged helix" DNA-binding domain | 0.5998 | Inherited |
| beta-beta-alpha zinc fingers | 0.6033 | Inherited |
| HMG-box | 0.6038 | Inherited |
| Serpins | 0.6178 | Inherited |
| Hemopexin-like domain | 0.6235 | Inherited |
| Cystatin/monellin | 0.6235 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.6269 | Inherited |
| MFS general substrate transporter | 0.631 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.6598 | Inherited |
| E2F-DP heterodimerization region | 0.6633 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.665 | Inherited |
| p53-like transcription factors | 0.6947 | Inherited |
| NAD(P)-linked oxidoreductase | 0.7014 | Inherited |
| Carbonic anhydrase | 0.7014 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.7205 | Inherited |
| PGBD-like | 0.7216 | Inherited |
| Caspase-like | 0.7404 | Inherited |
| GroEL equatorial domain-like | 0.7597 | Inherited |
| Arginase/deacetylase | 0.7597 | Inherited |
| GroEL apical domain-like | 0.7597 | Inherited |
| Ubiquitin-like | 0.7627 | Inherited |
| Polo-box domain | 0.7849 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.7896 | Inherited |
| cAMP-binding domain-like | 0.7931 | Inherited |
| GroEL-intermediate domain like | 0.7994 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.8012 | Inherited |
| Cytokine | 0.8012 | Inherited |
| Thioredoxin-like | 0.8125 | Inherited |
| Enolase C-terminal domain-like | 0.8288 | Inherited |
| Enolase N-terminal domain-like | 0.8288 | Inherited |
| Mitochondrial carrier | 0.8299 | Inherited |
| Nucleic acid-binding proteins | 0.837 | Inherited |
| SNARE-like | 0.8607 | Inherited |
| LDL receptor-like module | 0.8638 | Inherited |
| Actin-like ATPase domain | 0.878 | Inherited |
| Spermadhesin, CUB domain | 0.8823 | Inherited |
| TNF-like | 0.8823 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 0.8854 | Inherited |
| Inhibitor of apoptosis (IAP) repeat | 0.8859 | Inherited |
| Interleukin 8-like chemokines | 0.9072 | Inherited |
| S15/NS1 RNA-binding domain | 0.9085 | Inherited |
| Bromodomain | 0.9154 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.9204 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.922 | Inherited |
| Voltage-gated potassium channels | 0.9259 | Inherited |
| Sm-like ribonucleoproteins | 0.9289 | Inherited |
| Kazal-type serine protease inhibitors | 0.9359 | Inherited |
| Orange domain-like | 0.9436 | Inherited |
| (Trans)glycosidases | 0.9676 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.982 | Inherited |
| Cysteine proteinases | 0.982 | Inherited |
| DBL homology domain (DH-domain) | 0.9887 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| ADP-ribosylation | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| Snake toxin-like | 1 | Inherited |
| L domain-like | 1 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| HD-domain/PDEase-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Nicotinic receptor ligand binding domain-like | 1 | Inherited |
| 4-helical cytokines | 1 | Inherited |
| Intermediate filament protein, coiled coil region | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DNase I-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| AlkB-like | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Pentapeptide repeats | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Acetylcholinesterase-like | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Ornithine decarboxylase antizyme-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Alkaline phosphatase | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| A20-like zinc finger | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| Plakophilin 1 helical region | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Ribosomal protein L3 | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| FKBP immunophilin/proline isomerase | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Penta-EF-hand proteins | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | DIRECT |
| Synatpobrevin N-terminal domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| Bacterial PLC | 0 | DIRECT |
| SMAD4-binding domain of oncoprotein Ski | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Uteroglobin-like | 0 | DIRECT |
| Complement components | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| DEATH effector domain, DED | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Hermes transposase-like | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| TK-like Pyr module | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Cytidylytransferase | 0 | DIRECT |
| Lipoxigenase N-terminal domain | 0 | DIRECT |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| TatD Mg-dependent DNase-like | 0 | DIRECT |
| FucT-like | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| MIF-related | 0 | DIRECT |
| Platelet-derived growth factor-like | 0 | DIRECT |
| Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Selenoprotein W-related | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| PUG domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Dachshund-homology domain | 0 | DIRECT |
| FolH catalytic domain-like | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| SelR domain | 0 | DIRECT |
| Interferon regulatory factor | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Ribosomal proteins L24p and L21e | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Crisp domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Starch-binding domain | 0 | DIRECT |
| Transglutaminase N-terminal domain | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| Leukotriene A4 hydrolase C-terminal domain | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| SPOC domain | 0 | DIRECT |
| p53 DNA-binding domain-like | 0 | DIRECT |
| Synapsin domain | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Clathrin heavy-chain linker domain | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| Cysteine rich domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| IMD domain | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Centromere-binding | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Osteonectin | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| Lectin leg-like | 0 | DIRECT |
| GS domain | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Triple coiled coil domain of C-type lectins | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | DIRECT |
| VWC domain | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| RUN domain | 0 | DIRECT |
| HkH motif-containing C2H2 finger | 0 | DIRECT |
| GAT domain | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
| CPH domain | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| PIWI domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Nuclear movement domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Retinoblastoma tumor suppressor domains | 0 | DIRECT |
| ProC C-terminal domain-like | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Kringle modules | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| MYND zinc finger | 0 | DIRECT |
| Animal lipoxigenases | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| GABARAP-like | 0 | DIRECT |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Oligosaccharide phosphorylase | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| ECR1 N-terminal domain-like | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| Synapsin C-terminal domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| C2 set domains | 0 | DIRECT |
| Aminomethyltransferase folate-binding domain | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Family 1 of glycosyl hydrolase | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| PNP-oxidase like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| PCI domain (PINT motif) | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| Variant SAM domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Transglutaminase core | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| Caspase recruitment domain, CARD | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| 5' nucleotidase-like | 0 | DIRECT |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | DIRECT |
| Integrin beta EGF-like domains | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| gamma-adaptin C-terminal appendage domain-like | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| Exostosin | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Interleukin-1 (IL-1) | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| THAP domain | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | DIRECT |
| STAT DNA-binding domain | 0 | DIRECT |
| Cytochrome p450 reductase N-terminal domain-like | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Tyrosine-dependent oxidoreductases | 0 | DIRECT |
| Cripto EGF-like domain-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| MBT repeat | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| RGC domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Pyridoxal-dependent decarboxylase | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| TK-like PP module | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Carbamilase | 0 | DIRECT |
| STAR domain | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0.02008 | INHERITED FROM: Semaxinib || quercetin 4'-O-glucopyranoside || Tubercidin || baohuoside I || orantinib || indole-5-carboxamide || Cantharidin || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || Cyclic GMP || Benzopyrans || Folfox protocol || Coumarins || Quinazolines || Pyocyanine || Phenazines || dracorhodin || SU 6656 || APS-2-79 || 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbo || Heterocyclic Compounds, 3-Ring || Naphthyridines || pifithrin || 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide || 103D5R || Flavones || Citrinin || 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine || Adenosine Diphosphate || Isoindoles || Benzodioxoles || Indoles || bisindolylmaleimide || Isoquinolines || staurosporine aglycone || didymin || GSK 1363089 || rottlerin || Formyltetrahydrofolates || Quinoxalines || Carbazoles || deguelin || bisindolylmaleimide I || WHI P154 || fascaplysine || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || Quinolines || Sunitinib || dictamnine || 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone || coptisine || 1',2'-dihydrorotenone || dehydroglyasperin C || alvocidib || Benzimidazoles || napabucasin || aflatoxin B2 || Ochratoxins || Win 55212-2 || Benzothiazoles || 5-iodotubercidin || 6,7-dimethoxy-3-phenylquinoxaline || Polyphenols || Staurosporine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| LIM domain | 0.0599 | INHERITED FROM: Aflatoxin B1 |
| PLC-like (P variant) | 0.07362 | INHERITED FROM: aflatoxin B2 |
| MHC antigen-recognition domain | 0.1104 | INHERITED FROM: beta-Lactams || Benzothiadiazines || Gefitinib || Quinazolines || Ampicillin || Ketorolac || Diltiazem || Cephalosporins || Omeprazole || Quinolines || Penicillin G || Chlorothiazide |
| SH2 domain | 0.1603 | INHERITED FROM: 4'-methoxy licoflavanone || alpinumisoflavone || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine || isoquercitrin || WP1066 || Polyphenols || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside |
| Ras-binding domain, RBD | 0.1636 | INHERITED FROM: N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || Indazoles || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || Benzothiazoles |
| Cadherin | 0.1645 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
| Acetyl-CoA synthetase-like | 0.1746 | INHERITED FROM: Tetrachlorodibenzodioxin |
| Cyclin | 0.186 | INHERITED FROM: 7,3'-dihydroxy-4'-methoxyisoflavone || tylophorine || Indolizines || Flavanones || Quinazolines || abemaciclib || scriptaid || Folic Acid || Trabectedin || Aminoacridines || Citrinin || Ethidium || fludarabine || Phenanthridines || Isoquinolines || Chromans || Indazoles || Phenothiazines || cryptolepine || usnic acid || Chalcones || Silybin || Acridines || CP-654577 || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || 1',2'-dihydrorotenone || alvocidib || Hypoxanthines || Guanine || Vemurafenib || Ochratoxins || Benzothiazoles || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || AC 93253 || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| FHA domain | 0.186 | INHERITED FROM: fludarabine || Vidarabine |
| Growth factor receptor domain | 0.1892 | INHERITED FROM: Tetrachlorodibenzodioxin || Folfox protocol || Quinazolines || Heterocyclic Compounds, 3-Ring || Tetrahydrofolates || N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine || Formyltetrahydrofolates || Adenine Nucleotides || Penicillin G || Vemurafenib || CMF regimen |
| SH3-domain | 0.2062 | INHERITED FROM: aflatoxin B2 |
| Integrin A (or I) domain | 0.2106 | INHERITED FROM: GSK1210151A || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Calcimycin |
| G proteins | 0.2218 | INHERITED FROM: Guanine Nucleotides || Guanosine Triphosphate |
| Nucleosome core histones | 0.2222 | INHERITED FROM: Coumarins || Thioxanthenes || Xanthones || Folic Acid || Benzylisoquinolines || Berberine || OTX015 || Xanthenes || Isoquinolines || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || Grape Seed Proanthocyanidins || Heterocyclic Compounds, 4 or More Rings || Berberine Alkaloids || Lucanthone || Coumestrol |
| Fibronectin type III | 0.2401 | INHERITED FROM: Panobinostat || aflatoxin B2 |
| EGF-type module | 0.2579 | INHERITED FROM: Quinoxalines || Tyrphostins || Warfarin || RTKI cpd |
| Leucine zipper domain | 0.2621 | INHERITED FROM: Tetrachlorodibenzodioxin || Pteridines || Aminopterin || Vinca Alkaloids || quinomethionate || Heterocyclic Compounds, 3-Ring || Hemin || Penicillins || Citrinin || piperine || BIX 02189 || Phenanthrolines || Benzofurans || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Flavonoids || Phthalimides || Isoindoles || Benzodioxoles || Indoles || Isoquinolines || rottlerin || sauchinone || Quercetin || Quinoxalines || Quinolines || Tetrapyrroles || Cyclic AMP || Penicillin G || fisetin || Heterocyclic Compounds, 4 or More Rings || Uric Acid || Indole Alkaloids || Ochratoxins || 4-Quinolones || NSC668394 || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbamazepine |
| Chaperone J-domain | 0.2773 | INHERITED FROM: motexafin gadolinium || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Dibenzazepines || Carbamazepine |
| Nuclear receptor ligand-binding domain | 0.2857 | INHERITED FROM: Tetrachlorodibenzodioxin || Benzothiepins || pomiferin || Fluvastatin || Coumarins || Dronedarone || osajin || Quinazolines || Purine Nucleotides || puerarin || tegaserod || quinoxyfen || Reserpine || Heterocyclic Compounds, 3-Ring || 8-prenylnaringenin || Yohimbine || Furocoumarins || Benzoxazines || Aminoacridines || MK-886 || Flavones || Berberine || Benzofurans || kaempferol || Ro 41-5253 || Melatonin || Flavonoids || Nebivolol || ZK 216348 || Benzoflavones || Isoquinolines || Lansoprazole || biochanin A || Benomyl || pitavastatin || Emetine || galaxolide || Quercetin || Quinoxalines || 2-acetylphenothiazine || Tocopherols || Adenine Nucleotides || Carbazoles || Chromans || Phenothiazines || irilone || Quinolines || daidzein || Kaempferols || Silybin || Acridines || Rifamycins || Proflavine || Purines || chlormidazole || Heterocyclic Compounds, 4 or More Rings || norathyriol || flavone || Benzimidazoles || chrysin || icaritin || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tryptamines || 3-methylquercetin || Staurosporine |
| Pleckstrin-homology domain (PH domain) | 0.2909 | INHERITED FROM: Catechin || Indoles || Guanosine Triphosphate || aflatoxin B2 |
| PX domain | 0.294 | INHERITED FROM: Go 6976 |
| Extended AAA-ATPase domain | 0.294 | INHERITED FROM: Coumestrol |
| Nuclear receptor | 0.3026 | INHERITED FROM: Tetrachlorodibenzodioxin || Benzothiepins || pomiferin || Fluvastatin || Coumarins || Dronedarone || osajin || Quinazolines || Purine Nucleotides || puerarin || tegaserod || quinoxyfen || Reserpine || Heterocyclic Compounds, 3-Ring || 8-prenylnaringenin || Yohimbine || Benzoxazines || Aminoacridines || MK-886 || Flavones || Berberine || Benzofurans || kaempferol || Ro 41-5253 || Melatonin || Flavonoids || Nebivolol || ZK 216348 || Benzoflavones || Isoquinolines || Lansoprazole || biochanin A || Benomyl || pitavastatin || Emetine || galaxolide || Quercetin || Quinoxalines || 2-acetylphenothiazine || Tocopherols || Adenine Nucleotides || Carbazoles || Chromans || Phenothiazines || irilone || Quinolines || daidzein || Kaempferols || Silybin || Acridines || Rifamycins || Proflavine || Purines || chlormidazole || Heterocyclic Compounds, 4 or More Rings || norathyriol || flavone || Benzimidazoles || chrysin || icaritin || 3,3'-diindolylmethane || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tryptamines || 3-methylquercetin || Staurosporine |
| Frizzled cysteine-rich domain | 0.3275 | INHERITED FROM: Panobinostat || deguelin || 1-Methyl-3-isobutylxanthine || Carbamazepine |
| Motor proteins | 0.3303 | INHERITED FROM: Thioxanthenes || Xanthones || Folic Acid || Xanthenes || Lucanthone |
| C1 set domains (antibody constant domain-like) | 0.342 | INHERITED FROM: beta-Lactams || Benzothiadiazines || Gefitinib || Quinazolines || Ampicillin || Fluoroquinolones || Ketorolac || Diltiazem || Cephalosporins || Omeprazole || Penicillin G || Chlorothiazide |
| Proteasome subunits | 0.3481 | INHERITED FROM: quercitrin |
| Canonical RBD | 0.3634 | INHERITED FROM: PP242 || Vinca Alkaloids |
| Glutathione peroxidase-like | 0.3702 | INHERITED FROM: Flavanones || Quercetin || Tetrapyrroles || naringenin |
| S100 proteins | 0.3939 | INHERITED FROM: Tetrachlorodibenzodioxin || Heterocyclic Compounds, 3-Ring |
| Arylsulfatase | 0.3939 | INHERITED FROM: PP242 |
| GABA-aminotransferase-like | 0.4185 | INHERITED FROM: Tetrachlorodibenzodioxin || Heterocyclic Compounds, 3-Ring |
| Fibrinogen C-terminal domain-like | 0.4618 | INHERITED FROM: Adenosine Diphosphate |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.4727 | INHERITED FROM: scoparone || piperine || Isoindoles || Benzodioxoles || Harmala Alkaloids || bisindolylmaleimide I || fisetin || Benzoxazoles || Resveratrol || Calcimycin || Polyphenols || Carbolines |
| ABC transporter ATPase domain-like | 0.4967 | INHERITED FROM: 3',4',7-trihydroxyisoflavone || N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Secologanin Tryptamine Alkaloids || senecionine || Vinca Alkaloids || Nelfinavir || Penicillins || calcein AM || Furocoumarins || Fluoresceins || Benzofurans || Saquinavir || Rifampin || 6-bromoindirubin-3'-oxime || bisbenzimide ethoxide trihydrochloride || Xanthenes || 8-azidoadenosine 5'-triphosphate || fluorexon || Thioguanine || hesperetin || pitavastatin || Benzbromarone || Mefloquine || verlukast || Phenothiazines || Quinolines || Rifamycins || Methoxsalen || 2-Pyridinylmethylsulfinylbenzimidazoles || formononetin || Heterocyclic Compounds, 4 or More Rings || Benzimidazoles || chrysin || Adenosine Triphosphate || Ticlopidine || TAK-875 || Tolvaptan || Thienopyridines || AC 93253 |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.5016 | INHERITED FROM: Purine Nucleosides || Benzoflavones || Phenothiazines || senkirkine || Pyrrolizidine Alkaloids |
| SNARE fusion complex | 0.5296 | INHERITED FROM: Heroin || Morphinans || Morphine Derivatives |
| PAPS sulfotransferase | 0.5602 | INHERITED FROM: 2-amino-3-methyl-9H-pyrido(2,3-b)indole || Phosphoadenosine Phosphosulfate || Pyrrolizidine Alkaloids || Carbolines |
| Cell cycle transcription factor e2f-dp | 0.5642 | INHERITED FROM: Harmine || Coumarins || Azathioprine || Mercaptopurine || Harmala Alkaloids || Resveratrol || Ochratoxins || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Carbolines |
| Toll/Interleukin receptor TIR domain | 0.5758 | INHERITED FROM: 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || Aripiprazole || Erlotinib Hydrochloride || chrysin || E804 bisindole |
| HMG-box | 0.588 | INHERITED FROM: Polyphenols |
| Hemopexin-like domain | 0.5984 | INHERITED FROM: Benzodiazepines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || Purine Nucleosides || Benzylisoquinolines || Berberine || piperine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Ciprofloxacin || sauchinone || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Tyrphostins || dieckol || deguelin || Tetrapyrroles || varespladib methyl || Silybin || chrysin || Porphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Matrix metalloproteases, catalytic domain | 0.5984 | INHERITED FROM: manganese(III)-tetrakis(4-benzoic acid)porphyrin || Aminopterin || Quinazolines || Purine Nucleosides || Xanthones || piperine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Ciprofloxacin || sauchinone || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Quinoxalines || Tyrphostins || dieckol || deguelin || Tetrapyrroles || varespladib methyl || Silybin || chrysin || Porphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || RTKI cpd || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.5992 | INHERITED FROM: Troglitazone || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Quercetin || Chromans || Tetrapyrroles || usnic acid || Heterocyclic Compounds, 4 or More Rings || Benzimidazoles || Porphyrins |
| Histone lysine methyltransferases | 0.6095 | INHERITED FROM: Benzylisoquinolines || Berberine || Isoquinolines || Berberine Alkaloids |
| PDEase | 0.6095 | INHERITED FROM: Purine Nucleotides || NVP ABE171 || Naphthyridines || PF-04254644 || trequinsin || Tetrahydroisoquinolines || Isoquinolines || Quinolines || E 4021 |
| Serpins | 0.6141 | INHERITED FROM: Tetrachlorodibenzodioxin || periodate-oxidized adenosine || Rifampin || Benzoflavones || Polychlorinated Dibenzodioxins |
| UDPGT-like | 0.671 | INHERITED FROM: naringenin chalcone || 4-Hydroxycoumarins || Tetrachlorodibenzodioxin || Phloretin || 7,3'-dihydroxy-4'-methoxyisoflavone || grepafloxacin || Benzodiazepines || bergamottin || auriculasin || Ofloxacin || Flavanones || Coumarins || Benzodiazepinones || puerarin || glabridin || Heterocyclic Compounds, 3-Ring || Indoprofen || lorcaserin || Moxifloxacin || Furocoumarins || Indoleacetic Acids || Fluoroquinolones || Bile Pigments || amentoflavone || kaempferol || Rifampin || Umbelliferones || Isoindoles || 2',5'-dihydroxychalcone || 2',4'-dihydroxychalcone || Benzoflavones || MK-0524 || biochanin A || Oxazepam || Morphine || morin || Omeprazole || 7-hydroxy-4-(trifluoromethyl)coumarin || Indomethacin || daidzein || Hymecromone || Kaempferols || Polychlorinated Dibenzodioxins || mangiferin || Scopoletin || Chalcones || Silybin || 7-hydroxy-4-trifluoromethylcoumarin || Equol || licochalcone A || sitafloxacin || Biflavonoids || galangin || 2-Pyridinylmethylsulfinylbenzimidazoles || formononetin || fisetin || Heterocyclic Compounds, 4 or More Rings || Benzimidazoles || chrysin || Warfarin || Etodolac || Apigenin || Morphinans || Flavonolignans || naringenin || Pyrrolizidine Alkaloids || Morphine Derivatives || beta-Naphthoflavone |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0.6746 | INHERITED FROM: Vitamin E |
| Aldo-keto reductases (NADP) | 0.6795 | INHERITED FROM: beta-Lactams || Oxcarbazepine || Benzodiazepines || 1,10-phenanthroline || Purine Nucleotides || Benzodiazepinones || Penicillins || Medazepam || Ampicillin || Phenanthrolines || Azathioprine || Umbelliferones || Benzoflavones || Diazepam || Nitrazepam || Benzbromarone || Adenine Nucleotides || NADP || cloxazolam || Penicillin G || Estazolam || Oxyquinoline || Flunitrazepam || Benzothiazoles || NSC668394 || naringenin || beta-Naphthoflavone |
| Carbonic anhydrase | 0.6795 | INHERITED FROM: Benzothiazoles || Ethoxzolamide || Flavonolignans |
| MMP N-terminal domain | 0.6971 | INHERITED FROM: manganese(III)-tetrakis(4-benzoic acid)porphyrin || Aminopterin || Quinazolines || Xanthones || piperine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Ciprofloxacin || sauchinone || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Quinoxalines || Tyrphostins || dieckol || Carbazoles || deguelin || Tetrapyrroles || varespladib methyl || Silybin || chrysin || Porphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || RTKI cpd || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| A DNA-binding domain in eukaryotic transcription factors | 0.6994 | INHERITED FROM: Hemin || S-Adenosylmethionine || Tetrapyrroles || Heterocyclic Compounds, 4 or More Rings || Indole Alkaloids |
| L domain | 0.717 | INHERITED FROM: Pteridines || Folfox protocol || Quinazolines || Flavones || Tetrahydrofolates || Formyltetrahydrofolates || Quinoxalines || Tyrphostins || Indazoles || Resveratrol || Aminoquinolines || Lapatinib || CMF regimen || Polyphenols || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Clathrin coat assembly domain | 0.7193 | INHERITED FROM: PP242 |
| Spermadhesin, CUB domain | 0.7331 | INHERITED FROM: Panobinostat |
| Caspase catalytic domain | 0.7599 | INHERITED FROM: 2-Chloroadenosine || baohuoside I || Mitomycins || Chloroquine || Ellipticines || Benzodiazepines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 3',4'-dimethoxyflavone || 4-chromone || Cantharidin || polyphenon E || auriculasin || gardenin B || Flavanones || Secologanin Tryptamine Alkaloids || Fluvastatin || Pteridines || senecionine || mangostin || quinoline-val-asp(OMe)-CH2-OPH || Dactinomycin || phthalocyanine Pc 4 || 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline || Quinazolines || Benzodiazepinones || dracorhodin || Purine Nucleosides || NMS-873 || cyanidin 3-O-glucoside || Rutin || Xanthones || Naphthyridines || Anthocyanins || 2-hydroxy-3',5,5'-trimethoxychalcone || casticin || abexinostat || pifithrin || Furocoumarins || 6-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone || Indoleacetic Acids || Benzoxazines || Indolequinones || cobaltiprotoporphyrin || Fluoroquinolones || 9-hydroxycanthin-6-one || Aminoacridines || Clofarabine || SCIO-469 || Flavones || Berberine || Benzoxepins || fludarabine || Benzofurans || alpha-viniferin || anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione || 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one || kaempferol || Pentoxifylline || Melatonin || Phenanthridines || Rifampin || Umbelliferones || Benzophenanthridines || Phthalimides || dihydromyricetin || Deoxyadenosines || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || Isoindoles || Benzodioxoles || esculetin || Isoquinolines || Adenosine || gambogic acid || Bendamustine Hydrochloride || Riluzole || ellipticine || osthol || Ciprofloxacin || isoangustone A || Quercetin || Morphine || ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate || sanguinarine || echimidine || 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide || Tocopherols || morin || Adenine Nucleotides || tetrandrine || Carbazoles || indole-3-carbinol || Chromans || copper-1,10-phenanthroline || Quinolines || Adenine || Theobromine || sinularin || Chalcones || xanthohumol || Acridines || Equol || 3-methyladenine || paederosidic acid || idelalisib || Methoxsalen || Flavonols || MK 2206 || SNX 2112 || Vidarabine || alvocidib || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || formononetin || fisetin || Heterocyclic Compounds, 4 or More Rings || zinc protoporphyrin || Benzimidazoles || CFM 1 || 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane || chrysin || Benzoxazoles || Resveratrol || sesamol || p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane || Cladribine || Ochratoxins || Win 55212-2 || Aminoquinolines || Benzothiazoles || Calcimycin || senkirkine || heliotrine || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || 5,6-dichlorobenzimidazole || Etodolac || lonidamine || Tryptamines || Apigenin || quercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside || trovafloxacin || (2)-5,6,7,8,4'-pentamethoxyflavanone || Flavonolignans || myricetin || Polyphenols || Pyrrolizidine Alkaloids || Staurosporine || Morphine Derivatives || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Short-chain cytokines | 0.7599 | INHERITED FROM: epinastine || Pteridines || 6,2',4'-trimethoxyflavone || Bucladesine || Flavones || kaempferol || Flavonoids || Phthalimides || Isoindoles || pomalidomide || 7-bromoindirubin-3'-oxime || Chromones || Cytochalasins || Quinoxalines || Tyrphostins || Quinolines || Thalidomide || fisetin || Benzoxazoles || Resveratrol || E804 bisindole || Calcimycin || Cytochalasin B || Polyphenols || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| TRASH domain | 0.7609 | INHERITED FROM: Aflatoxin M1 |
| Histone deacetylase, HDAC | 0.8021 | INHERITED FROM: Benzothiepins || polyphenon E || Benzylisoquinolines || Berberine || Isoquinolines |
| cAMP-binding domain | 0.8228 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Purine Nucleotides |
| Mitochondrial carrier | 0.828 | INHERITED FROM: Adenosine Triphosphate |
| LDL receptor-like module | 0.8479 | INHERITED FROM: Olanzapine |
| Classic zinc finger, C2H2 | 0.8493 | INHERITED FROM: GSK-J4 || Aflatoxin M1 || Benzazepines || pomalidomide |
| Voltage-gated potassium channels | 0.8514 | INHERITED FROM: Astemizole || Quinidine |
| Long-chain cytokines | 0.8531 | INHERITED FROM: Apomorphine || Purine Nucleotides || 6,2',4'-trimethoxyflavone || Azathioprine || Isoindoles || Isoquinolines || 7-bromoindirubin-3'-oxime || Aripiprazole || Quinoxalines || Adenine Nucleotides || Clozapine || Aporphines || Thalidomide || Benzimidazoles || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || E804 bisindole || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Polo-box duplicated region | 0.8543 | INHERITED FROM: Genistein |
| Inhibitor of apoptosis (IAP) repeat | 0.8697 | INHERITED FROM: Secologanin Tryptamine Alkaloids || Quinazolines || Purine Nucleosides || Flavones || EKB 569 || Pentoxifylline || Isoquinolines || Adenosine || Bendamustine Hydrochloride || Quinoxalines || morin || Carbazoles || indole-3-carbinol || Quinolines || Theobromine || Vinblastine || Chalcones || N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine || alvocidib || Benzimidazoles || Resveratrol || Porphyrins || Polyphenols || evodiamine || Staurosporine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Fibronectin type II module | 0.8795 | INHERITED FROM: baicalein || Flavanones || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Phenanthridines || Benzophenanthridines || Quinoxalines || Tyrphostins || Tetrapyrroles || chrysin || Porphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Apigenin |
| TNF-like | 0.8915 | INHERITED FROM: Phenanthridines || Benzophenanthridines || candesartan || Quinolones || Aripiprazole || sanguinarine || Clozapine || Vemurafenib |
| Interleukin 8-like chemokines | 0.8979 | INHERITED FROM: captax || 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline || coralyne || 3'-methoxy-4'-nitroflavone || Dequalinium || Pteridines || Aminopterin || Vinca Alkaloids || Troglitazone || Puromycin || PD168393 || Telmisartan || Rutin || Hesperidin || Quinolinium Compounds || 6,2',4'-trimethoxyflavone || Albendazole || Flavones || Propidium || Phenanthridines || palmatine || 7-bromoindirubin-3'-oxime || Quinolones || Aripiprazole || Emetine || Allopurinol || Pterins || Quinolines || 6-formylindolo(3,2-b)carbazole || Benzimidazoles || Benzoxazoles || E804 bisindole || Calcimycin || Morphinans || Polyphenols || Morphine Derivatives |
| Bromodomain | 0.9062 | INHERITED FROM: OTX015 || Chromans |
| HLH, helix-loop-helix DNA-binding domain | 0.9128 | INHERITED FROM: Anthocyanins || 2,3,7,8-tetrachlorodibenzofuran || Rifampin || baicalin || Indican || 2,3,4,7,8-pentachlorodibenzofuran || galangin |
| Fibroblast growth factors (FGF) | 0.9177 | INHERITED FROM: 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Hairy Orange domain | 0.9295 | INHERITED FROM: baicalein || Flavanones || baicalin |
| TBP-associated factors, TAFs | 0.9507 | INHERITED FROM: Aflatoxin M1 |
| DBL homology domain (DH-domain) | 0.9841 | INHERITED FROM: aflatoxin B2 |
| Actin/HSP70 | 0.9862 | INHERITED FROM: Caffeine || Metalloporphyrins || Hemin || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || indirubin-3'-monoxime || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Benzimidazoles |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 1 | INHERITED FROM: PP242 |
| Transforming growth factor (TGF)-beta | 1 | INHERITED FROM: Purine Nucleotides || Adenine Nucleotides || Cyclic AMP || fulvic acid || Calcimycin || Protoporphyrins |
| Insulin-like | 1 | INHERITED FROM: Benzimidazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Pyrin domain, PYD | 1 | INHERITED FROM: Adenosine Triphosphate |
| Gonadodropin/Follitropin | 1 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Purine Nucleotides || Isoquinolines || Adenine Nucleotides || Cyclic AMP |
| I set domains | 1 | INHERITED FROM: Lenalidomide || aflatoxin B2 |
| Rhodopsin-like | 1 | INHERITED FROM: Lurasidone Hydrochloride || 7-hydroxymitragynine || abanoquil || Ketanserin || 7-fluoro-2-oxo-4-(2-(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)ethyl)-1,2-dihydroquinoline-1-aceta || proanthocyanidin || brucine N-oxide || alfuzosin || A 86929 || Strychnine || 7-methyl-6,7,8,9,14,15-hexahydro-5H-benz(d)indolo(2,3-g)azecine || indole || 1,3-dipropyl-8-cyclopentylxanthine || quercitrin || (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) || Idazoxan |
| Interferons/interleukin-10 (IL-10) | 1 | INHERITED FROM: beta-Lactams || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Tyrphostins || 6-formylindolo(3,2-b)carbazole || gardiquimod || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || Aminoquinolines |
| Homeodomain | 1 | INHERITED FROM: Panobinostat |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: GSK-J4 || Aflatoxin M1 || Benzazepines |
| Nicotinic receptor ligand binding domain-like | 1 | INHERITED FROM: Atracurium || Benzodiazepines || Mivacurium || L 663581 || Ro 15-4513 || Benzylisoquinolines || Isoquinolines || Dihydro-beta-Erythroidine || Quinolizines || cisatracurium || cytisine || desformylflustrabromine || Bicuculline || Tubocurarine || bretazenil |
| Eukaryotic proteases | 1 | INHERITED FROM: 4-Hydroxycoumarins || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Warfarin |
| Intermediate filament protein, coiled coil region | 1 | INHERITED FROM: flavone |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | INHERITED FROM: Atracurium || Benzodiazepines || Mivacurium || L 663581 || Ro 15-4513 || Benzylisoquinolines || Isoquinolines || Dihydro-beta-Erythroidine || Quinolizines || cisatracurium || cytisine || desformylflustrabromine || Bicuculline || Tubocurarine || bretazenil |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DNase I-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| RWD domain | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| AlkB-like | 0 | Direct |
| U-box | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Pentapeptide repeats | 0 | Direct |
| Connexin43 | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Acetylcholinesterase-like | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Ornithine decarboxylase antizyme-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| BolA-like | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Alkaline phosphatase | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| A20-like zinc finger | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| Plakophilin 1 helical region | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Ribosomal protein L3 | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Class I aldolase | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| FKBP immunophilin/proline isomerase | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | Direct |
| AXH domain | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Penta-EF-hand proteins | 0 | Direct |
| ALDH-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | Direct |
| Synatpobrevin N-terminal domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| FF domain | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| LON domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| APC10-like | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| Bacterial PLC | 0 | Direct |
| SMAD4-binding domain of oncoprotein Ski | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Ferritin | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Uteroglobin-like | 0 | Direct |
| Complement components | 0 | Direct |
| DNA ligase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Subtilases | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| DEATH effector domain, DED | 0 | Direct |
| PWI domain | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Integrin domains | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Paired domain | 0 | Direct |
| Hermes transposase-like | 0 | Direct |
| CUT domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| MAPEG domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| NagB-like | 0 | Direct |
| TK-like Pyr module | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Cytidylytransferase | 0 | Direct |
| Lipoxigenase N-terminal domain | 0 | Direct |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Multidrug resistance efflux transporter EmrE | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| DLC | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Translational machinery components | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| STAT | 0 | Direct |
| TatD Mg-dependent DNase-like | 0 | Direct |
| FucT-like | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| Metallothionein | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| MIF-related | 0 | Direct |
| Platelet-derived growth factor-like | 0 | Direct |
| Pseudouridine synthase RsuA/RluD | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | Direct |
| Troponin T | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Selenoprotein W-related | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| PUG domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Dachshund-homology domain | 0 | Direct |
| FolH catalytic domain-like | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Crotonase-like | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| SelR domain | 0 | Direct |
| Interferon regulatory factor | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Ribosomal proteins L24p and L21e | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| HMGL-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Crisp domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| CCHHC domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Starch-binding domain | 0 | Direct |
| Transglutaminase N-terminal domain | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| Leukotriene A4 hydrolase C-terminal domain | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| LysM domain | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Choline kinase | 0 | Direct |
| SPOC domain | 0 | Direct |
| p53 DNA-binding domain-like | 0 | Direct |
| Synapsin domain | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| NIPSNAP | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Clathrin heavy-chain linker domain | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| Cysteine rich domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Transferrin | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| IMD domain | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| CAT-like | 0 | Direct |
| L27 domain | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| AAT-like | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Prefoldin | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Troponin I | 0 | Direct |
| YWTD domain | 0 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Sema domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| NagD-like | 0 | Direct |
| GLA-domain | 0 | Direct |
| Centromere-binding | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Osteonectin | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| Lectin leg-like | 0 | Direct |
| GS domain | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Triple coiled coil domain of C-type lectins | 0 | Direct |
| BRK domain-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | Direct |
| VWC domain | 0 | Direct |
| LanC-like | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| RUN domain | 0 | Direct |
| HkH motif-containing C2H2 finger | 0 | Direct |
| GAT domain | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| CUE domain | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | Direct |
| B56-like | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| MSP-like | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Notch domain | 0 | Direct |
| PUA domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
| CPH domain | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| PIWI domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Nuclear movement domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| COMT-like | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Retinoblastoma tumor suppressor domains | 0 | Direct |
| ProC C-terminal domain-like | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| SNF-like | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Kringle modules | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| MYND zinc finger | 0 | Direct |
| Animal lipoxigenases | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| WWE domain | 0 | Direct |
| VHS domain | 0 | Direct |
| GABARAP-like | 0 | Direct |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Oligosaccharide phosphorylase | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| UBA domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| ECR1 N-terminal domain-like | 0 | Direct |
| Hexokinase | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| Synapsin C-terminal domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Macro domain | 0 | Direct |
| C2 set domains | 0 | Direct |
| Aminomethyltransferase folate-binding domain | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Fumble-like | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Family 1 of glycosyl hydrolase | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| PNP-oxidase like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| PCI domain (PINT motif) | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Reductases | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| beta-glycanases | 0 | Direct |
| Variant SAM domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Nop domain | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| PB1 domain | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| BSD domain | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| WGR domain | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| LeuD-like | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| UBX domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Transglutaminase core | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| SRF-like | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Papain-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| Caspase recruitment domain, CARD | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| 5' nucleotidase-like | 0 | Direct |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | Direct |
| Integrin beta EGF-like domains | 0 | Direct |
| PKD domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| gamma-adaptin C-terminal appendage domain-like | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| Exostosin | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Synuclein | 0 | Direct |
| TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Interleukin-1 (IL-1) | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Variant RING domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| THAP domain | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| HR1 repeat | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| SMAD domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| GYF domain | 0 | Direct |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | Direct |
| STAT DNA-binding domain | 0 | Direct |
| Cytochrome p450 reductase N-terminal domain-like | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Tyrosine-dependent oxidoreductases | 0 | Direct |
| Cripto EGF-like domain-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| HCP-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| MIR domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| MBT repeat | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| CAD domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| RGC domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Pyridoxal-dependent decarboxylase | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| TK-like PP module | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Chromo domain | 0 | Direct |
| Cullin repeat | 0 | Direct |
| GRAM domain | 0 | Direct |
| Carbamilase | 0 | Direct |
| STAR domain | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| Protein kinases, catalytic subunit | 0.02008 | Inherited |
| LIM domain | 0.0599 | Inherited |
| PLC-like (P variant) | 0.07362 | Inherited |
| MHC antigen-recognition domain | 0.1104 | Inherited |
| SH2 domain | 0.1603 | Inherited |
| Ras-binding domain, RBD | 0.1636 | Inherited |
| Cadherin | 0.1645 | Inherited |
| Acetyl-CoA synthetase-like | 0.1746 | Inherited |
| Cyclin | 0.186 | Inherited |
| FHA domain | 0.186 | Inherited |
| Growth factor receptor domain | 0.1892 | Inherited |
| SH3-domain | 0.2062 | Inherited |
| Integrin A (or I) domain | 0.2106 | Inherited |
| G proteins | 0.2218 | Inherited |
| Nucleosome core histones | 0.2222 | Inherited |
| Fibronectin type III | 0.2401 | Inherited |
| EGF-type module | 0.2579 | Inherited |
| Leucine zipper domain | 0.2621 | Inherited |
| Chaperone J-domain | 0.2773 | Inherited |
| Nuclear receptor ligand-binding domain | 0.2857 | Inherited |
| Pleckstrin-homology domain (PH domain) | 0.2909 | Inherited |
| PX domain | 0.294 | Inherited |
| Extended AAA-ATPase domain | 0.294 | Inherited |
| Nuclear receptor | 0.3026 | Inherited |
| Frizzled cysteine-rich domain | 0.3275 | Inherited |
| Motor proteins | 0.3303 | Inherited |
| C1 set domains (antibody constant domain-like) | 0.342 | Inherited |
| Proteasome subunits | 0.3481 | Inherited |
| Canonical RBD | 0.3634 | Inherited |
| Glutathione peroxidase-like | 0.3702 | Inherited |
| S100 proteins | 0.3939 | Inherited |
| Arylsulfatase | 0.3939 | Inherited |
| GABA-aminotransferase-like | 0.4185 | Inherited |
| Fibrinogen C-terminal domain-like | 0.4618 | Inherited |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.4727 | Inherited |
| ABC transporter ATPase domain-like | 0.4967 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.5016 | Inherited |
| SNARE fusion complex | 0.5296 | Inherited |
| PAPS sulfotransferase | 0.5602 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.5642 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.5758 | Inherited |
| HMG-box | 0.588 | Inherited |
| Hemopexin-like domain | 0.5984 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.5984 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.5992 | Inherited |
| Histone lysine methyltransferases | 0.6095 | Inherited |
| PDEase | 0.6095 | Inherited |
| Serpins | 0.6141 | Inherited |
| UDPGT-like | 0.671 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0.6746 | Inherited |
| Aldo-keto reductases (NADP) | 0.6795 | Inherited |
| Carbonic anhydrase | 0.6795 | Inherited |
| MMP N-terminal domain | 0.6971 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.6994 | Inherited |
| L domain | 0.717 | Inherited |
| Clathrin coat assembly domain | 0.7193 | Inherited |
| Spermadhesin, CUB domain | 0.7331 | Inherited |
| Caspase catalytic domain | 0.7599 | Inherited |
| Short-chain cytokines | 0.7599 | Inherited |
| TRASH domain | 0.7609 | Inherited |
| Histone deacetylase, HDAC | 0.8021 | Inherited |
| cAMP-binding domain | 0.8228 | Inherited |
| Mitochondrial carrier | 0.828 | Inherited |
| LDL receptor-like module | 0.8479 | Inherited |
| Classic zinc finger, C2H2 | 0.8493 | Inherited |
| Voltage-gated potassium channels | 0.8514 | Inherited |
| Long-chain cytokines | 0.8531 | Inherited |
| Polo-box duplicated region | 0.8543 | Inherited |
| Inhibitor of apoptosis (IAP) repeat | 0.8697 | Inherited |
| Fibronectin type II module | 0.8795 | Inherited |
| TNF-like | 0.8915 | Inherited |
| Interleukin 8-like chemokines | 0.8979 | Inherited |
| Bromodomain | 0.9062 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.9128 | Inherited |
| Fibroblast growth factors (FGF) | 0.9177 | Inherited |
| Hairy Orange domain | 0.9295 | Inherited |
| TBP-associated factors, TAFs | 0.9507 | Inherited |
| DBL homology domain (DH-domain) | 0.9841 | Inherited |
| Actin/HSP70 | 0.9862 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 1 | Inherited |
| Transforming growth factor (TGF)-beta | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| Pyrin domain, PYD | 1 | Inherited |
| Gonadodropin/Follitropin | 1 | Inherited |
| I set domains | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Interferons/interleukin-10 (IL-10) | 1 | Inherited |
| Homeodomain | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| Nicotinic receptor ligand binding domain-like | 1 | Inherited |
| Eukaryotic proteases | 1 | Inherited |
| Intermediate filament protein, coiled coil region | 1 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Hairpin loop containing domain-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Hermes dimerisation domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| FKBP-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Triple coiled coil domain of C-type lectins | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Uteroglobin-like | 0 | DIRECT |
| Lipoxigenase | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Probable bacterial effector-binding domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| STAT | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Pentapeptide repeat-like | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.006791 | INHERITED FROM: ZK 216348 || 2-acetylphenothiazine || Acridines || Emetine || Ro 41-5253 || Isoquinolines || 3-methylquercetin || osajin || Heterocyclic Compounds, 4 or More Rings || quinoxyfen || irilone || Reserpine || Aminoacridines || Staurosporine || Benzothiepins || Purine Nucleotides || Benomyl || flavone || Quinolines || galaxolide || Dronedarone || pomiferin || Silybin || kaempferol || chlormidazole || Flavonoids || biochanin A || pitavastatin || norathyriol || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || icaritin || Adenine Nucleotides || tegaserod || daidzein || Nebivolol || Kaempferols || Benzoxazines || Proflavine |
| ARM repeat | 0.01005 | INHERITED FROM: N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0111 | INHERITED FROM: aflatoxin B2 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| Protein kinase-like (PK-like) | 0.01894 | INHERITED FROM: dehydroglyasperin C || 5-iodotubercidin || Tocopherols || napabucasin || Quinazolines || fascaplysine || abemaciclib || Benzimidazoles || Trifluoperazine || Isoquinolines || Cantharidin || 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine || Adenosine Diphosphate || alvocidib || Benzothiazoles || alsterpaullone || baohuoside I || Tubercidin || Indoles || aflatoxin B2 || Benzodioxoles || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || Indazoles || Phenazines || GSK 1363089 || Citrinin || APS-2-79 || pifithrin || Polyphenols || Win 55212-2 || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || esculetin || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || coptisine || 6,7-dimethoxy-3-phenylquinoxaline || rottlerin || Semaxinib || Staurosporine || tylophorine || dictamnine || 1',2'-dihydrorotenone || Quinolines || copper-1,10-phenanthroline || Sterigmatocystin || Isoindoles || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || Sunitinib || dracorhodin || Pyocyanine || didymin || indole-5-carboxamide || Anthocyanins || bisindolylmaleimide I || WHI P154 || 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline || fisetin || quercetin 4'-O-glucopyranoside || Benzopyrans || Chromans || Quinoxalines || dihydromyricetin || SU 6656 || 6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one || isoquercitrin || 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbo || orantinib || 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone || staurosporine aglycone || 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione || bisindolylmaleimide || deguelin || Cyclic GMP || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Chromones || Folfox protocol || Flavones || 2''-galloylhyperin || Benzoxazines || Xanthenes || 103D5R || 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide || Indolizines || Ochratoxins || Coumarins || LM-1685 || Heterocyclic Compounds, 3-Ring || Naphthyridines |
| SMAD/FHA domain | 0.03184 | INHERITED FROM: casticin || osthol || galangin || Polyphenols || Cytochalasin D || Vidarabine || Cytochalasins || fludarabine |
| PH domain-like | 0.03904 | INHERITED FROM: Catechin || (N)-methanocarba-2MeSADP || Indoles || aflatoxin B2 || Benzopyrans |
| NAD(P)-binding Rossmann-fold domains | 0.0439 | INHERITED FROM: Oxcarbazepine || Isatin || Purines || NAD || Purine Nucleotides || NADP || Adenine Nucleotides || Heterocyclic Compounds, 3-Ring |
| GTPase activation domain, GAP | 0.06397 | INHERITED FROM: aflatoxin B2 |
| PLP-dependent transferases | 0.07072 | INHERITED FROM: Tetrachlorodibenzodioxin || adefovir dipivoxil |
| Periplasmic binding protein-like I | 0.08744 | INHERITED FROM: Citalopram |
| MHC antigen-recognition domain | 0.09373 | INHERITED FROM: Quinazolines || Ketorolac || Gefitinib || Omeprazole || Fluoroquinolones || Quinolines || Ampicillin || Benzothiadiazines || Diltiazem || beta-Lactams || Penicillin G || Cephalosporins || Chlorothiazide || 2-Pyridinylmethylsulfinylbenzimidazoles |
| vWA-like | 0.09378 | INHERITED FROM: 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| Galactose-binding domain-like | 0.1086 | INHERITED FROM: Indoles |
| P-loop containing nucleoside triphosphate hydrolases | 0.1211 | INHERITED FROM: Tolvaptan || 5-carboxyfluorescein diacetate || bisbenzimide ethoxide trihydrochloride || Guanosine Triphosphate || calcein AM || Vinca Alkaloids || 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)a || TAK-875 || pitavastatin || Coumestrol || 5(6)-carboxy-2',7'-dichlorofluorescein || fluorexon || Thioxanthenes || Elacridar || Phosphoadenosine Phosphosulfate || AC 93253 || Xanthenes || verlukast |
| PDZ domain-like | 0.1228 | INHERITED FROM: Heterocyclic Compounds, 2-Ring || aflatoxin B2 |
| Cadherin-like | 0.1242 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
| SH2 domain | 0.1309 | INHERITED FROM: alpinumisoflavone || 4'-methoxy licoflavanone || Polyphenols || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Flavonoids || N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine || isoquercitrin || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || Carbamazepine || WP1066 || Heterocyclic Compounds, 3-Ring |
| Alkaline phosphatase-like | 0.1413 | INHERITED FROM: PP242 |
| Acetyl-CoA synthetase-like | 0.1515 | INHERITED FROM: Tetrachlorodibenzodioxin || Pyrrolizidine Alkaloids |
| EGF/Laminin | 0.1588 | INHERITED FROM: GSK1210151A || Tetrachlorodibenzodioxin || Pteridines || aflatoxin B2 || Etodolac || Quinoxalines || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Heterocyclic Compounds, 3-Ring |
| SH3-domain | 0.1589 | INHERITED FROM: aflatoxin B2 |
| E set domains | 0.1609 | INHERITED FROM: Calcimycin || Carbolines || Harmala Alkaloids || 6-isopropoxy-9-oxoxanthene-2-carboxylic acid || scoparone || piperine || Benzoxazoles || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole |
| Fibronectin type III | 0.1947 | INHERITED FROM: Panobinostat || aflatoxin B2 |
| FAD/NAD(P)-binding domain | 0.2053 | INHERITED FROM: Purine Nucleosides || Indazoles || Benzydamine || Benzoflavones || senkirkine || Pyrrolizidine Alkaloids |
| Leucine zipper domain | 0.2254 | INHERITED FROM: 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Uric Acid || Tetrachlorodibenzodioxin || Quinazolines || Pteridines || Benzofurans || NSC668394 || Isoquinolines || quinomethionate || Indoles || Heterocyclic Compounds, 4 or More Rings || Aminopterin || Quercetin || Benzodioxoles || Cyclic AMP || Citrinin || sauchinone || BIX 02189 || Vinca Alkaloids || 4-Quinolones || Phenanthrolines || rottlerin || Quinolines || Isoindoles || Phthalimides || alpha-Tocopherol || Flavonoids || Tetrapyrroles || fisetin || Quinoxalines || Penicillins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Hemin || piperine || Penicillin G || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Carbamazepine || Indole Alkaloids || Ochratoxins || Heterocyclic Compounds, 3-Ring |
| TNF receptor-like | 0.226 | INHERITED FROM: Quinazolines || Pteridines || Vemurafenib || osthol || Polyphenols || Benzophenanthridines || licochalcone A || Quinolines || Isoindoles || Vidarabine || Pentoxifylline || Genistein || Theobromine || sanguinarine || Aripiprazole || Flavones || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Quinolones || fludarabine || motexafin gadolinium |
| Growth factor receptor domain | 0.2289 | INHERITED FROM: napabucasin || Quinazolines || Pteridines || Formyltetrahydrofolates || CMF regimen || Adenine Nucleotides || Troglitazone || Folfox protocol || Flavones || baicalin || Heterocyclic Compounds, 3-Ring |
| PX domain | 0.2326 | INHERITED FROM: Go 6976 |
| Cyclin-like | 0.2374 | INHERITED FROM: Hypoxanthines || Tocopherols || Quinazolines || Acridines || Ro 41-5253 || Vemurafenib || abemaciclib || Benzimidazoles || alvocidib || Benzothiazoles || Tyrphostins || Trabectedin || Roscovitine || Ethidium || Guanine || Indazoles || CP-654577 || Citrinin || THRX 165724 || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-d || Aminoacridines || rottlerin || tylophorine || 1',2'-dihydrorotenone || Quinolines || cryptolepine || scriptaid || Flavanones || Silybin || Phenanthridines || Chromans || Quinoxalines || MK-886 || AC 93253 || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Indolizines || Ochratoxins || fludarabine || 7,3'-dihydroxy-4'-methoxyisoflavone || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin |
| Chaperone J-domain | 0.2396 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Dibenzazepines || Carbamazepine || motexafin gadolinium |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.2434 | INHERITED FROM: procyanidin B2 || Berberine Alkaloids || S-Adenosylmethionine || Pyrrolizidine Alkaloids |
| Nuclear receptor ligand-binding domain | 0.2473 | INHERITED FROM: 3,3'-diindolylmethane || Furocoumarins || Tocopherols || Tetrachlorodibenzodioxin || Quinazolines || ZK 216348 || 2-acetylphenothiazine || Acridines || Yohimbine || Benzofurans || Emetine || Ro 41-5253 || Benzimidazoles || Isoquinolines || 3-methylquercetin || osajin || Heterocyclic Compounds, 4 or More Rings || Quercetin || quinoxyfen || puerarin || Polyphenols || irilone || Reserpine || Purines || Aminoacridines || Staurosporine || Benzothiepins || Purine Nucleotides || chrysin || Melatonin || Benomyl || flavone || Quinolines || 8-prenylnaringenin || galaxolide || Dronedarone || Isoindoles || Fluvastatin || pomiferin || Flavanones || Silybin || kaempferol || chlormidazole || Flavonoids || Rifamycins || biochanin A || indole-3-carbinol || Flavonolignans || pitavastatin || Chromans || Quinoxalines || Tryptamines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || norathyriol || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || Benzoflavones || icaritin || Adenine Nucleotides || Berberine || tegaserod || daidzein || Lansoprazole || Phenothiazines || Nebivolol || MK-886 || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Kaempferols || Flavones || Benzoxazines || Coumarins || verlukast || Proflavine || Heterocyclic Compounds, 3-Ring |
| WW domain | 0.2553 | INHERITED FROM: aflatoxin B2 |
| SET domain | 0.2719 | INHERITED FROM: Isoquinolines || Berberine Alkaloids || Benzylisoquinolines || Berberine |
| Frizzled cysteine-rich domain | 0.2935 | INHERITED FROM: Panobinostat || 1-Methyl-3-isobutylxanthine || deguelin || Theophylline || Carbamazepine |
| Histone-fold | 0.3481 | INHERITED FROM: Isoquinolines || Heterocyclic Compounds, 4 or More Rings || Lucanthone || OTX015 || Berberine Alkaloids || Benzylisoquinolines || Xanthones || Coumestrol || Thioxanthenes || Berberine || Folic Acid || Xanthenes || Coumarins |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.3934 | INHERITED FROM: Warfarin || Furocoumarins || Scopoletin || morin || Tetrachlorodibenzodioxin || Indoleacetic Acids || formononetin || Benzimidazoles || Phloretin || Chalcones || Oxazepam || Morphine || Morphinans || Biflavonoids || Morphine Derivatives || mangiferin || auriculasin || naringenin chalcone || Equol || galangin || Omeprazole || puerarin || Etodolac || Fluoroquinolones || Indoprofen || licochalcone A || bergamottin || chrysin || MK-0524 || beta-Naphthoflavone || 2',5'-dihydroxychalcone || Umbelliferones || lorcaserin || Flavanones || Silybin || 4-Hydroxycoumarins || kaempferol || Benzodiazepinones || glabridin || sitafloxacin || biochanin A || fisetin || Flavonolignans || 7-hydroxy-4-trifluoromethylcoumarin || amentoflavone || Benzoflavones || Moxifloxacin || Ofloxacin || naringenin || daidzein || Pyrrolizidine Alkaloids || Apigenin || grepafloxacin || 7-hydroxy-4-(trifluoromethyl)coumarin || Kaempferols || 2',4'-dihydroxychalcone || 7,3'-dihydroxy-4'-methoxyisoflavone || Benzodiazepines || 2-Pyridinylmethylsulfinylbenzimidazoles || Hymecromone |
| DEATH domain | 0.3946 | INHERITED FROM: tetrandrine || Tocopherols || Purine Nucleosides || casticin || morin || polyphenon E || Quinazolines || Indoleacetic Acids || Pteridines || Benzofurans || Cladribine || Vemurafenib || Isoquinolines || Chalcones || Cantharidin || Calcimycin || alvocidib || 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid || Benzothiazoles || osthol || Heterocyclic Compounds, 4 or More Rings || auriculasin || Quercetin || Bendamustine Hydrochloride || Guanine || CFM 1 || Polyphenols || Win 55212-2 || Adenine || esculetin || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Benzophenanthridines || KN 62 || Staurosporine || Porphyrins || Ciprofloxacin || tylophorine || Quinolines || abexinostat || Adenosine || Umbelliferones || Isoindoles || Flavanones || Dactinomycin || SRT2183 || echimidine || dracorhodin || Vidarabine || Pentoxifylline || Genistein || Phthalimides || Benzodiazepinones || Flavonoids || Phenanthridines || Quinazolinones || Allopurinol || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || Tetrapyrroles || fisetin || indole-3-carbinol || Flavonolignans || Theobromine || N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide || sanguinarine || idelalisib || EKB 569 || Carbazoles || Apigenin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavones || Benzoxazines || gardenin B || Indolizines || Pterins || quinoline-val-asp(OMe)-CH2-OPH || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Riluzole || Quinolones || fludarabine |
| FnI-like domain | 0.4016 | INHERITED FROM: GSK1210151A || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Quinazolines || Pteridines || Porphyrins || Dactinomycin || Quinazolinones || Tetrapyrroles || Benzopyrans || Adenine Nucleotides || Pterins || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| Terpenoid cyclases/Protein prenyltransferases | 0.4039 | INHERITED FROM: Olanzapine || Benzodiazepines |
| Fibrinogen C-terminal domain-like | 0.4142 | INHERITED FROM: Adenosine Diphosphate |
| Translation proteins SH3-like domain | 0.4309 | INHERITED FROM: Vitamin E |
| RNA-binding domain, RBD | 0.4733 | INHERITED FROM: PP242 || Vinca Alkaloids || Vitamin E |
| SNARE fusion complex | 0.48 | INHERITED FROM: Morphinans || Morphine Derivatives || Heroin |
| Toll/Interleukin receptor TIR domain | 0.4943 | INHERITED FROM: E804 bisindole || Erlotinib Hydrochloride || chrysin || Quinolines || 7-bromoindirubin-3'-oxime || Aripiprazole || 6,2',4'-trimethoxyflavone |
| Kringle-like | 0.4943 | INHERITED FROM: 3,3'-diindolylmethane || Tocopherols || GSK1210151A || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Quinazolines || Chalcones || Benzophenanthridines || carbendazim || Porphyrins || chrysin || Benomyl || Chlorpromazine || Flavanones || Dactinomycin || Silybin || kaempferol || baicalein || Tetrapyrroles || Flavonolignans || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Apigenin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Benzoxazines || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || 3-hydroxyflavone || Benzodiazepines |
| HSP20-like chaperones | 0.5097 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Adenosine Triphosphate |
| BRCT domain | 0.5258 | INHERITED FROM: fludarabine |
| "Winged helix" DNA-binding domain | 0.5285 | INHERITED FROM: Harmala Alkaloids || Harmine || Lucanthone |
| beta-beta-alpha zinc fingers | 0.532 | INHERITED FROM: pomalidomide || GSK-J4 || Benzazepines || Aflatoxin M1 |
| HMG-box | 0.5324 | INHERITED FROM: Polyphenols |
| Serpins | 0.5464 | INHERITED FROM: periodate-oxidized adenosine || Tetrachlorodibenzodioxin || Polychlorinated Dibenzodioxins || Benzoflavones || Rifampin |
| Cystatin/monellin | 0.5521 | INHERITED FROM: Lucanthone || Thioxanthenes |
| Hemopexin-like domain | 0.5521 | INHERITED FROM: Purine Nucleosides || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Quinazolines || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || manganese(III)-tetrakis(4-benzoic acid)porphyrin || Tyrphostins || Benzodioxoles || sauchinone || Porphyrins || Ciprofloxacin || chrysin || Silybin || Benzylisoquinolines || Tetrapyrroles || Flavonolignans || Quinoxalines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Berberine || piperine || varespladib methyl || deguelin || dieckol || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Benzodiazepines |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.5554 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Benzimidazoles || Heterocyclic Compounds, 4 or More Rings || Quercetin || Indazoles || Porphyrins || Tetrapyrroles || Chromans || Troglitazone || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || usnic acid |
| MFS general substrate transporter | 0.5594 | INHERITED FROM: Uric Acid || Quinine || Phloretin || Imipramine || Carbolines || Serotonin || Heterocyclic Compounds, 4 or More Rings || Ethidium || Ceftibuten || Fluoresceins || Mirtazapine || Cytochalasin B || Cephalexin || 6-carboxyfluorescein || Quinolizines || pseudoisocyanine || Rifamycins || Formyltetrahydrofolates || Quinidine || 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole || 7-(deoxyguanosin-N(2)-yl)aristolactam I || 2-amino-3,4-dimethylimidazo(4,5-f)quinoline || 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine || Rifampin || 7-(deoxyadenosin-N(6)-yl)aristolactam I || Heterocyclic Compounds, 3-Ring |
| Metalloproteases ("zincins"), catalytic domain | 0.5882 | INHERITED FROM: 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || manganese(III)-tetrakis(4-benzoic acid)porphyrin || Tyrphostins || sauchinone || Benomyl || benazepril || piperine || varespladib methyl || deguelin || dieckol || RTKI cpd |
| E2F-DP heterodimerization region | 0.5917 | INHERITED FROM: Ochratoxins || Coumarins |
| FAD-linked reductases, C-terminal domain | 0.5932 | INHERITED FROM: periodate-oxidized adenosine |
| p53-like transcription factors | 0.6228 | INHERITED FROM: alpha-naphthoflavone || alpinumisoflavone || Morphine || Calcimycin || Luteolin || Morphine Derivatives || Benzothiazoles || Carbolines || Harmala Alkaloids || Ergolines || Tyrphostins || Benzodioxoles || 4'-methoxy licoflavanone || Pergolide || Polyphenols || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || esculetin || Vinca Alkaloids || Phenanthrolines || Staurosporine || chrysin || Chloroquine || Umbelliferones || Isoindoles || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Flavanones || Dactinomycin || SRT2183 || Cytochalasins || 4-Hydroxycoumarins || Benzodiazepinones || Anthocyanins || bisindolylmaleimide I || Dicumarol || Ellagic Acid || fisetin || myricetin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || isoquercitrin || scoparone || piperine || Carbazoles || Apigenin || Kaempferols || Flavones || Benzoxazoles || Resveratrol |
| NAD(P)-linked oxidoreductase | 0.6297 | INHERITED FROM: Oxcarbazepine || NSC668394 || Benzothiazoles || cloxazolam || Flunitrazepam || Diazepam || Phenanthrolines || Purine Nucleotides || Nitrazepam || Ampicillin || beta-Naphthoflavone || Umbelliferones || Estazolam || Flavanones || beta-Lactams || Benzodiazepinones || Azathioprine || 1,10-phenanthroline || quinocetone || Penicillins || Benzoflavones || Medazepam || NADP || Adenine Nucleotides || Penicillin G || naringenin || Oxyquinoline || Benzbromarone || Benzodiazepines |
| Carbonic anhydrase | 0.6297 | INHERITED FROM: Benzothiazoles || Flavonolignans || Ethoxzolamide |
| A DNA-binding domain in eukaryotic transcription factors | 0.6492 | INHERITED FROM: Heterocyclic Compounds, 4 or More Rings || Isoindoles || S-Adenosylmethionine || Tetrapyrroles || Hemin || Indole Alkaloids || Resveratrol || Rifampin |
| PGBD-like | 0.6504 | INHERITED FROM: 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Quinazolines || Pteridines || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || manganese(III)-tetrakis(4-benzoic acid)porphyrin || Tyrphostins || Aminopterin || Benzodioxoles || sauchinone || Porphyrins || Ciprofloxacin || chrysin || Silybin || Benzylisoquinolines || Tetrapyrroles || Xanthones || Flavonolignans || Quinoxalines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Isoflavones || piperine || varespladib methyl || deguelin || dieckol || RTKI cpd || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Caspase-like | 0.6689 | INHERITED FROM: Furocoumarins || tetrandrine || Tocopherols || Purine Nucleosides || casticin || morin || mangostin || polyphenon E || ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate || Quinazolines || Indoleacetic Acids || Acridines || Pteridines || Benzofurans || Cladribine || Catechin || NMS-873 || Ellipticines || formononetin || Benzimidazoles || xanthohumol || Isoquinolines || Chalcones || Cantharidin || 5,6-dichlorobenzimidazole || Morphine || Calcimycin || Morphine Derivatives || alvocidib || Benzothiazoles || 3',4'-dimethoxyflavone || baohuoside I || osthol || Heterocyclic Compounds, 4 or More Rings || manganese(III)-tetrakis(4-benzoic acid)porphyrin || auriculasin || Quercetin || Benzoxepins || Benzodioxoles || Equol || Mitomycins || Flavonols || Bendamustine Hydrochloride || MK 2206 || quercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside || CFM 1 || pifithrin || Polyphenols || Etodolac || Win 55212-2 || Adenine || Methoxsalen || esculetin || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Fluoroquinolones || (2)-5,6,7,8,4'-pentamethoxyflavanone || Aminoacridines || Benzophenanthridines || anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione || rottlerin || 3-methyladenine || Staurosporine || Ciprofloxacin || chrysin || Melatonin || Chloroquine || 6-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone || senecionine || Quinolines || copper-1,10-phenanthroline || abexinostat || Secologanin Tryptamine Alkaloids || phthalocyanine Pc 4 || p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane || Adenosine || Umbelliferones || Isoindoles || Fluvastatin || 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one || Flavanones || Dactinomycin || echimidine || dracorhodin || Rutin || Vidarabine || cobaltiprotoporphyrin || Pentoxifylline || Phthalimides || kaempferol || Benzylisoquinolines || zinc protoporphyrin || sinularin || Benzodiazepinones || Anthocyanins || sesamol || cyanidin 3-O-glucoside || Phenanthridines || Quinazolinones || SCIO-469 || 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || 9-hydroxycanthin-6-one || fisetin || Xanthones || indole-3-carbinol || Flavonolignans || 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide || Chromans || Theobromine || Deoxyadenosines || dihydromyricetin || ellipticine || myricetin || Tryptamines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || sanguinarine || idelalisib || Adenine Nucleotides || Berberine || deguelin || senkirkine || paederosidic acid || trovafloxacin || Pyrrolizidine Alkaloids || alpha-viniferin || SNX 2112 || 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane || Carbazoles || Apigenin || lonidamine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavones || Benzoxazines || 2-hydroxy-3',5,5'-trimethoxychalcone || 2-Chloroadenosine || gardenin B || Benzoxazoles || Resveratrol || 4-chromone || Indolequinones || Pterins || quinoline-val-asp(OMe)-CH2-OPH || Rifampin || isoangustone A || usnic acid || gambogic acid || Clofarabine || Riluzole || Ochratoxins || fludarabine || Benzodiazepines || Naphthyridines || heliotrine |
| Arginase/deacetylase | 0.6887 | INHERITED FROM: polyphenon E || Isoquinolines || Benzothiepins || Benzylisoquinolines || Berberine |
| GroEL equatorial domain-like | 0.6887 | INHERITED FROM: Albendazole |
| GroEL apical domain-like | 0.6887 | INHERITED FROM: Albendazole |
| Ubiquitin-like | 0.6918 | INHERITED FROM: N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.7092 | INHERITED FROM: Aminopterin |
| Polo-box domain | 0.715 | INHERITED FROM: Genistein || Troglitazone |
| Ribosomal protein S5 domain 2-like | 0.7199 | INHERITED FROM: Hypoxanthines || Adenosine Triphosphate || Guanine || O(6)-benzylguanine |
| cAMP-binding domain-like | 0.7238 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide |
| GroEL-intermediate domain like | 0.7304 | INHERITED FROM: Benzimidazoles || Albendazole |
| PYP-like sensor domain (PAS domain) | 0.7322 | INHERITED FROM: 2,3,4,7,8-pentachlorodibenzofuran || 3,3'-diindolylmethane || Acridines || Benzimidazoles || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || epicatechin gallate || galangin || Omeprazole || Polyphenols || Semaxinib || kaempferol || Anthocyanins || Rifamycins || 1,10-phenanthroline || 2,3,7,8-tetrachlorodibenzofuran || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Kaempferols || Flavones || Indican || Rifampin || gallocatechol || 3-hydroxyflavone |
| Cytokine | 0.7322 | INHERITED FROM: Quinazolines || Phloretin || Flavonolignans || Penicillins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || usnic acid |
| Thioredoxin-like | 0.7439 | INHERITED FROM: xanthohumol || apple polyphenol extract || Chlorophyllides || captafol || KT 5720 || Amodiaquine || Captan || Tetrapyrroles || desethylamodiaquine || Quinidine || Bile Pigments || amodiaquine quinoneimine |
| Enolase N-terminal domain-like | 0.761 | INHERITED FROM: Pteridines || Aminopterin || Pterins |
| Enolase C-terminal domain-like | 0.761 | INHERITED FROM: Pteridines || Aminopterin || Pterins |
| Mitochondrial carrier | 0.7623 | INHERITED FROM: Adenosine Triphosphate |
| Nucleic acid-binding proteins | 0.77 | INHERITED FROM: cryptolepine || Chromans || Coumarins |
| Ankyrin repeat | 0.7805 | INHERITED FROM: EKB 569 |
| SNARE-like | 0.7948 | INHERITED FROM: PP242 |
| LDL receptor-like module | 0.7983 | INHERITED FROM: Olanzapine |
| Actin-like ATPase domain | 0.8136 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Benzimidazoles || indirubin-3'-monoxime || PP242 || Hemin || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || Caffeine |
| TNF-like | 0.8182 | INHERITED FROM: Vemurafenib || Calcimycin || Benzophenanthridines || Phenanthridines || Clozapine || sanguinarine || Aripiprazole || Quinolones || candesartan |
| Spermadhesin, CUB domain | 0.8182 | INHERITED FROM: Panobinostat |
| Inhibitor of apoptosis (IAP) repeat | 0.822 | INHERITED FROM: Purine Nucleosides || morin || Quinazolines || Benzimidazoles || Isoquinolines || Chalcones || evodiamine || alvocidib || Bendamustine Hydrochloride || Polyphenols || Staurosporine || Porphyrins || Quinolines || Secologanin Tryptamine Alkaloids || Adenosine || N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine || Pentoxifylline || indole-3-carbinol || Theobromine || Quinoxalines || EKB 569 || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavones || Vinblastine || Resveratrol |
| Interleukin 8-like chemokines | 0.8448 | INHERITED FROM: palmatine || Pteridines || Emetine || Hesperidin || E804 bisindole || Quinolinium Compounds || Benzimidazoles || Morphinans || Calcimycin || Morphine Derivatives || PD168393 || Aminopterin || Propidium || Polyphenols || Vinca Alkaloids || Quinolines || Secologanin Tryptamine Alkaloids || Rutin || Phenanthridines || Allopurinol || Puromycin || coralyne || 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline || 3'-methoxy-4'-nitroflavone || captax || 7-bromoindirubin-3'-oxime || Troglitazone || Aripiprazole || Dequalinium || Flavones || Albendazole || 6-formylindolo(3,2-b)carbazole || Benzoxazoles || Pterins || 6,2',4'-trimethoxyflavone || Quinolones || Telmisartan |
| S15/NS1 RNA-binding domain | 0.8463 | INHERITED FROM: Isocoumarins || Ochratoxins |
| Bromodomain | 0.8537 | INHERITED FROM: OTX015 || Chromans |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.8592 | INHERITED FROM: Vitamin E |
| HLH, helix-loop-helix DNA-binding domain | 0.861 | INHERITED FROM: 2,3,4,7,8-pentachlorodibenzofuran || galangin || Genistein || Anthocyanins || 2,3,7,8-tetrachlorodibenzofuran || Indican || Rifampin || baicalin || 3-hydroxyflavone |
| Voltage-gated potassium channels | 0.8651 | INHERITED FROM: Mibefradil || Tetrodotoxin || Astemizole |
| Sm-like ribonucleoproteins | 0.8684 | INHERITED FROM: PP242 |
| Kazal-type serine protease inhibitors | 0.8761 | INHERITED FROM: naringin |
| Orange domain-like | 0.8845 | INHERITED FROM: Flavanones || baicalein || baicalin |
| (Trans)glycosidases | 0.9116 | INHERITED FROM: PP242 |
| BPTI-like | 0.9119 | INHERITED FROM: Mitomycins || Indolequinones |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.9187 | INHERITED FROM: quercitrin |
| G protein-binding domain | 0.9233 | INHERITED FROM: Dibenzazepines || Carbamazepine |
| Concanavalin A-like lectins/glucanases | 0.928 | INHERITED FROM: Panobinostat |
| Cysteine proteinases | 0.928 | INHERITED FROM: benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide |
| DBL homology domain (DH-domain) | 0.9356 | INHERITED FROM: aflatoxin B2 |
| Nicotinic receptor ligand binding domain-like | 0.964 | INHERITED FROM: Isoquinolines || Tubocurarine || Ro 15-4513 || Mivacurium || cisatracurium || Atracurium || cytisine || desformylflustrabromine || bretazenil || Dihydro-beta-Erythroidine || Quinolizines || Benzylisoquinolines || L 663581 || Bicuculline || Benzodiazepines |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.964 | INHERITED FROM: Isoquinolines || Tubocurarine || Ro 15-4513 || Mivacurium || cisatracurium || Atracurium || cytisine || desformylflustrabromine || bretazenil || Dihydro-beta-Erythroidine || Quinolizines || Benzylisoquinolines || L 663581 || Bicuculline || Benzodiazepines |
| alpha/beta-Hydrolases | 0.9753 | INHERITED FROM: Morphine Derivatives || 6-O-monoacetylmorphine || Galantamine || Physostigmine || Tacrine || Heroin |
| HD-domain/PDEase-like | 0.9758 | INHERITED FROM: Tetrahydroisoquinolines || Isoquinolines || Purine Nucleotides || PF-04254644 || NVP ABE171 || Quinolines || E 4021 || trequinsin || Naphthyridines |
| ADP-ribosylation | 0.981 | INHERITED FROM: veliparib || XAV939 || rucaparib |
| Intermediate filament protein, coiled coil region | 0.9878 | INHERITED FROM: flavone |
| Snake toxin-like | 0.9989 | INHERITED FROM: rutecarpine |
| C-type lectin-like | 1 | INHERITED FROM: Nebivolol |
| Trypsin-like serine proteases | 1 | INHERITED FROM: Warfarin || nothofagin || 4-Hydroxycoumarins || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || aspalathin |
| Cystine-knot cytokines | 1 | INHERITED FROM: GSK1210151A || Uric Acid || Quinazolines || Isoquinolines || Morphinans || Calcimycin || Heterocyclic Compounds, 4 or More Rings || delphinidin || Purine Nucleotides || Protoporphyrins || Isoindoles || Anthocyanins || N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || cyanidin || fulvic acid || MOPP protocol || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Adenine Nucleotides || Ramipril || Carbazoles || Benzoxazoles || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: GSK-J4 || Benzazepines || Aflatoxin M1 |
| Immunoglobulin | 1 | INHERITED FROM: Ketorolac || gardiquimod || Lenalidomide || Benzothiadiazines || beta-Lactams || thieno(2,3-c)isoquinolin-5-one || orantinib || HX 630 || Aripiprazole || 3,5-di-tert-butylchalcone 4'-carboxylic acid || Cephalosporins |
| L domain-like | 1 | INHERITED FROM: CMF regimen || Folfox protocol |
| Homeodomain-like | 1 | INHERITED FROM: Panobinostat |
| Insulin-like | 1 | INHERITED FROM: Benzimidazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| 4-helical cytokines | 1 | INHERITED FROM: 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Pteridines || Hesperidin || E804 bisindole || Ro 41-5253 || Benzimidazoles || Isoquinolines || Phloretin || epinastine || Morphinans || Calcimycin || Ergolines || Tyrphostins || Benzodioxoles || Polyphenols || Aporphines || rottlerin || Ciprofloxacin || chrysin || montelukast || NVP ABE171 || Quinolines || Chlorpromazine || hesperetin || Isoindoles || Dactinomycin || Phthalimides || beta-Lactams || Cytochalasins || kaempferol || Azathioprine || StemRegenin 1 || bisindolylmaleimide I || Clozapine || Apomorphine || Tetrapyrroles || fisetin || Flavonolignans || Quinoxalines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Adenine Nucleotides || 7-bromoindirubin-3'-oxime || Aripiprazole || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Kaempferols || Flavones || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || 6-formylindolo(3,2-b)carbazole || Benzoxazoles || 6,2',4'-trimethoxyflavone || Naphthyridines |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: brucine N-oxide || proanthocyanidin || Idazoxan || Lurasidone Hydrochloride || 7-fluoro-2-oxo-4-(2-(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)ethyl)-1,2-dihydroquinoline-1-aceta || quercitrin || A 86929 || alfuzosin || abanoquil || 1,3-dipropyl-8-cyclopentylxanthine || (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) || indole || Ketanserin || 7-methyl-6,7,8,9,14,15-hexahydro-5H-benz(d)indolo(2,3-g)azecine || 7-hydroxymitragynine |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Hairpin loop containing domain-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Nop domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Pentein | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| KA1-like | 0 | Direct |
| GroES-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| ALDH-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Notch domain | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Macro domain-like | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Hermes dimerisation domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| ITPase-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| LanC-like | 0 | Direct |
| HCP-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| eIF1-like | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| BEACH domain | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Thiolase-like | 0 | Direct |
| L27 domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| SIS domain | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| GLA-domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| ClpS-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| WWE domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Mss4-like | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| LigT-like | 0 | Direct |
| N-(deoxy)ribosyltransferase-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| eIF4e-like | 0 | Direct |
| ADC-like | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| PUG domain-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| FKBP-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| HIT-like | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| PKD domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| FF domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| BolA-like | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| DLC | 0 | Direct |
| Triple coiled coil domain of C-type lectins | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Connexin43 | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| SNF-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Metallothionein | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| LysM domain | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| GYF domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| ISP domain | 0 | Direct |
| Uteroglobin-like | 0 | Direct |
| Lipoxigenase | 0 | Direct |
| PapD-like | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| AXH domain | 0 | Direct |
| ACP-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| SRF-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| L30e-like | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| Probable bacterial effector-binding domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| AhpD-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| Aldolase | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| LCCL domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| BAG domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| DNA clamp | 0 | Direct |
| BSD domain-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| GFP-like | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| STAT | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Synuclein | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| TIMP-like | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| PWI domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Plexin repeat | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Pentapeptide repeat-like | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| RGC domain-like | 0 | Direct |
| Sema domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.006791 | Inherited |
| ARM repeat | 0.01005 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0111 | Inherited |
| Protein kinase-like (PK-like) | 0.01894 | Inherited |
| SMAD/FHA domain | 0.03184 | Inherited |
| PH domain-like | 0.03904 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.0439 | Inherited |
| GTPase activation domain, GAP | 0.06397 | Inherited |
| PLP-dependent transferases | 0.07072 | Inherited |
| Periplasmic binding protein-like I | 0.08744 | Inherited |
| MHC antigen-recognition domain | 0.09373 | Inherited |
| vWA-like | 0.09378 | Inherited |
| Galactose-binding domain-like | 0.1086 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.1211 | Inherited |
| PDZ domain-like | 0.1228 | Inherited |
| Cadherin-like | 0.1242 | Inherited |
| SH2 domain | 0.1309 | Inherited |
| Alkaline phosphatase-like | 0.1413 | Inherited |
| Acetyl-CoA synthetase-like | 0.1515 | Inherited |
| EGF/Laminin | 0.1588 | Inherited |
| SH3-domain | 0.1589 | Inherited |
| E set domains | 0.1609 | Inherited |
| Fibronectin type III | 0.1947 | Inherited |
| FAD/NAD(P)-binding domain | 0.2053 | Inherited |
| Leucine zipper domain | 0.2254 | Inherited |
| TNF receptor-like | 0.226 | Inherited |
| Growth factor receptor domain | 0.2289 | Inherited |
| PX domain | 0.2326 | Inherited |
| Cyclin-like | 0.2374 | Inherited |
| Chaperone J-domain | 0.2396 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.2434 | Inherited |
| Nuclear receptor ligand-binding domain | 0.2473 | Inherited |
| WW domain | 0.2553 | Inherited |
| SET domain | 0.2719 | Inherited |
| Frizzled cysteine-rich domain | 0.2935 | Inherited |
| Histone-fold | 0.3481 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.3934 | Inherited |
| DEATH domain | 0.3946 | Inherited |
| FnI-like domain | 0.4016 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 0.4039 | Inherited |
| Fibrinogen C-terminal domain-like | 0.4142 | Inherited |
| Translation proteins SH3-like domain | 0.4309 | Inherited |
| RNA-binding domain, RBD | 0.4733 | Inherited |
| SNARE fusion complex | 0.48 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.4943 | Inherited |
| Kringle-like | 0.4943 | Inherited |
| HSP20-like chaperones | 0.5097 | Inherited |
| BRCT domain | 0.5258 | Inherited |
| "Winged helix" DNA-binding domain | 0.5285 | Inherited |
| beta-beta-alpha zinc fingers | 0.532 | Inherited |
| HMG-box | 0.5324 | Inherited |
| Serpins | 0.5464 | Inherited |
| Cystatin/monellin | 0.5521 | Inherited |
| Hemopexin-like domain | 0.5521 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.5554 | Inherited |
| MFS general substrate transporter | 0.5594 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.5882 | Inherited |
| E2F-DP heterodimerization region | 0.5917 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5932 | Inherited |
| p53-like transcription factors | 0.6228 | Inherited |
| NAD(P)-linked oxidoreductase | 0.6297 | Inherited |
| Carbonic anhydrase | 0.6297 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.6492 | Inherited |
| PGBD-like | 0.6504 | Inherited |
| Caspase-like | 0.6689 | Inherited |
| Arginase/deacetylase | 0.6887 | Inherited |
| GroEL equatorial domain-like | 0.6887 | Inherited |
| GroEL apical domain-like | 0.6887 | Inherited |
| Ubiquitin-like | 0.6918 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.7092 | Inherited |
| Polo-box domain | 0.715 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.7199 | Inherited |
| cAMP-binding domain-like | 0.7238 | Inherited |
| GroEL-intermediate domain like | 0.7304 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.7322 | Inherited |
| Cytokine | 0.7322 | Inherited |
| Thioredoxin-like | 0.7439 | Inherited |
| Enolase N-terminal domain-like | 0.761 | Inherited |
| Enolase C-terminal domain-like | 0.761 | Inherited |
| Mitochondrial carrier | 0.7623 | Inherited |
| Nucleic acid-binding proteins | 0.77 | Inherited |
| Ankyrin repeat | 0.7805 | Inherited |
| SNARE-like | 0.7948 | Inherited |
| LDL receptor-like module | 0.7983 | Inherited |
| Actin-like ATPase domain | 0.8136 | Inherited |
| TNF-like | 0.8182 | Inherited |
| Spermadhesin, CUB domain | 0.8182 | Inherited |
| Inhibitor of apoptosis (IAP) repeat | 0.822 | Inherited |
| Interleukin 8-like chemokines | 0.8448 | Inherited |
| S15/NS1 RNA-binding domain | 0.8463 | Inherited |
| Bromodomain | 0.8537 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.8592 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.861 | Inherited |
| Voltage-gated potassium channels | 0.8651 | Inherited |
| Sm-like ribonucleoproteins | 0.8684 | Inherited |
| Kazal-type serine protease inhibitors | 0.8761 | Inherited |
| Orange domain-like | 0.8845 | Inherited |
| (Trans)glycosidases | 0.9116 | Inherited |
| BPTI-like | 0.9119 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.9187 | Inherited |
| G protein-binding domain | 0.9233 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.928 | Inherited |
| Cysteine proteinases | 0.928 | Inherited |
| DBL homology domain (DH-domain) | 0.9356 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.964 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.964 | Inherited |
| alpha/beta-Hydrolases | 0.9753 | Inherited |
| HD-domain/PDEase-like | 0.9758 | Inherited |
| ADP-ribosylation | 0.981 | Inherited |
| Intermediate filament protein, coiled coil region | 0.9878 | Inherited |
| Snake toxin-like | 0.9989 | Inherited |
| C-type lectin-like | 1 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| L domain-like | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| 4-helical cytokines | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
54909,54909
54909 - Dimeric alpha+beta barrel
54909 - Dimeric alpha+beta barrel | 0 | DIRECT |
57196,56496
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | DIRECT |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49695,50370
49695 - gamma-Crystallin-like
50370 - Ricin B-like lectins | 0 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | DIRECT |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
51905,47576
51905 - FAD/NAD(P)-binding domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
47576,143575
47576 - Calponin-homology domain, CH-domain
143575 - GAS2 domain-like | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
56801,56801
56801 - Acetyl-CoA synthetase-like
56801 - Acetyl-CoA synthetase-like | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48371,49348
48371 - ARM repeat
49348 - Clathrin adaptor appendage domain | 0 | DIRECT |
52540,50729
52540 - P-loop containing nucleoside triphosphate hydrolases
50729 - PH domain-like | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
52087,48350
52087 - CRAL/TRIO domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
48452,48403
48452 - TPR-like
48403 - Ankyrin repeat | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | DIRECT |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | DIRECT |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
82199,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | DIRECT |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54695,54695
54695 - POZ domain
54695 - POZ domain | 0 | DIRECT |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | DIRECT |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
46955,63763
46955 - Putative DNA-binding domain
63763 - SAND domain-like | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
50249,46785
50249 - Nucleic acid-binding proteins
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
54277,50156
54277 - CAD & PB1 domains
50156 - PDZ domain-like | 0 | DIRECT |
47353,109640
47353 - Retrovirus capsid dimerization domain-like
109640 - KRAB domain (Kruppel-associated box) | 0 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
50370,57440
50370 - Ricin B-like lectins
57440 - Kringle-like | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
54416,54416
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region | 0 | DIRECT |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | DIRECT |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57440,56436
57440 - Kringle-like
56436 - C-type lectin-like | 0 | DIRECT |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | DIRECT |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
48452,48371
48452 - TPR-like
48371 - ARM repeat | 0 | DIRECT |
49299,49299
49299 - PKD domain
49299 - PKD domain | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
52540,90002
52540 - P-loop containing nucleoside triphosphate hydrolases
90002 - Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | DIRECT |
50729,50729
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
100895,48726
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | DIRECT |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54928,57756
54928 - RNA-binding domain, RBD
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
103657,48350
103657 - BAR/IMD domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
56496,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | DIRECT |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0 | DIRECT |
53300,69179
53300 - vWA-like
69179 - Integrin domains | 0 | DIRECT |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
57944,56436
57944 - Triple coiled coil domain of C-type lectins
56436 - C-type lectin-like | 0 | DIRECT |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
102848,54236
102848 - NSFL1 (p97 ATPase) cofactor p47, SEP domain
54236 - Ubiquitin-like | 0 | DIRECT |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | DIRECT |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | DIRECT |
81837,50978
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | DIRECT |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | DIRECT |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | DIRECT |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
54928,90209
54928 - RNA-binding domain, RBD
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
50729,46785
50729 - PH domain-like
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
48371,101447
48371 - ARM repeat
101447 - Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
46579,64593
46579 - Prefoldin
64593 - Intermediate filament protein, coiled coil region | 0 | DIRECT |
48670,48097
48670 - Transducin (heterotrimeric G protein), gamma chain
48097 - Regulator of G-protein signaling, RGS | 0 | DIRECT |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
47113,-7
47113 - Histone-fold
-7 - CATH | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | DIRECT |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
81901,81901
81901 - HCP-like
81901 - HCP-like | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
50044,47769
50044 - SH3-domain
47769 - SAM/Pointed domain | 0 | DIRECT |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57196,69687
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
57302,57302
57302 - Snake toxin-like
57302 - Snake toxin-like | 0 | DIRECT |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
54416,49998
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | DIRECT |
47473,57610
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
48452,81901
48452 - TPR-like
81901 - HCP-like | 0 | DIRECT |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
90193,90193
90193 - Notch domain
90193 - Notch domain | 0 | DIRECT |
57581,57581
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | DIRECT |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | DIRECT |
64593,90257
64593 - Intermediate filament protein, coiled coil region
90257 - Myosin rod fragments | 0 | DIRECT |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
90229,57850
90229 - CCCH zinc finger
57850 - RING/U-box | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49410,50242
49410 - Alpha-macroglobulin receptor domain
50242 - TIMP-like | 0 | DIRECT |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | DIRECT |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | DIRECT |
47576,140612
47576 - Calponin-homology domain, CH-domain
140612 - EB1 dimerisation domain-like | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.07594 | INHERITED FROM: Benzodioxoles || Naphthyridines |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.1343 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.1515 | INHERITED FROM: Quinazolines || Ketorolac || Gefitinib || Omeprazole || Fluoroquinolones || Quinolines || Ampicillin || Benzothiadiazines || Diltiazem || beta-Lactams || Penicillin G || Vitamin E || Cephalosporins || Chlorothiazide || 2-Pyridinylmethylsulfinylbenzimidazoles |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.2097 | INHERITED FROM: aflatoxin B2 |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0.2118 | INHERITED FROM: quinocetone |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.2118 | INHERITED FROM: 3,3'-diindolylmethane || Hypoxanthines || Tocopherols || Quinazolines || Acridines || Vemurafenib || abemaciclib || Benzimidazoles || Isoquinolines || Chalcones || alvocidib || Benzothiazoles || Trabectedin || Lucanthone || Ethidium || Guanine || Indazoles || CP-654577 || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Aminoacridines || tylophorine || 1',2'-dihydrorotenone || cryptolepine || scriptaid || Flavanones || Silybin || Benzylisoquinolines || Phenanthridines || Flavonolignans || Chromans || Berberine || Phenothiazines || AC 93253 || Folic Acid || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavones || Resveratrol || Indolizines || usnic acid || fludarabine || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.3542 | INHERITED FROM: Lenalidomide |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.4271 | INHERITED FROM: Tocopherols || Quinazolines || Acridines || Benzofurans || Emetine || Ro 41-5253 || Benzimidazoles || Isoquinolines || 3-methylquercetin || osajin || Heterocyclic Compounds, 4 or More Rings || Quercetin || puerarin || Polyphenols || irilone || Purines || Aminoacridines || Staurosporine || Benzothiepins || Purine Nucleotides || chrysin || adefovir dipivoxil || Melatonin || flavone || Quinolines || galaxolide || Dronedarone || Fluvastatin || pomiferin || scriptaid || kaempferol || Flavonoids || bisindolylmaleimide I || Rifamycins || Ellagic Acid || biochanin A || pitavastatin || Chromans || Quinoxalines || Tryptamines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || norathyriol || Adenine Nucleotides || daidzein || Phenothiazines || Nebivolol || MK-886 || Carbazoles || Coenzyme A || Chromones || Kaempferols || Flavones || Benzoxazines || Coumarins || Proflavine || Heterocyclic Compounds, 3-Ring |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.4402 | INHERITED FROM: Tocopherols |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4569 | INHERITED FROM: GSK1210151A || napabucasin || Panobinostat || Quinoxalines || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.48 | INHERITED FROM: napabucasin |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.5917 | INHERITED FROM: Ochratoxins || Coumarins |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.6504 | INHERITED FROM: 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Quinazolines || Pteridines || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || manganese(III)-tetrakis(4-benzoic acid)porphyrin || Tyrphostins || Aminopterin || Benzodioxoles || sauchinone || Porphyrins || Ciprofloxacin || chrysin || Silybin || Benzylisoquinolines || Tetrapyrroles || Xanthones || Flavonolignans || Quinoxalines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Isoflavones || piperine || varespladib methyl || deguelin || dieckol || RTKI cpd || Carbazoles || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.6689 | INHERITED FROM: Luteolin || Isoindoles || S-Adenosylmethionine || Tetrapyrroles || Quinoxalines || Hemin || Indole Alkaloids || Rifampin |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.672 | INHERITED FROM: Quinazolines || Pteridines || Lapatinib || Tyrphostins || Indazoles || Polyphenols || Quinolines || Aminoquinolines || Tetrahydrofolates || Formyltetrahydrofolates || Quinoxalines || CMF regimen || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Folfox protocol || Flavones || Resveratrol |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.672 | INHERITED FROM: Quinazolines || Pteridines || Lapatinib || Tyrphostins || Indazoles || Polyphenols || Quinolines || Aminoquinolines || Tetrahydrofolates || Formyltetrahydrofolates || Quinoxalines || CMF regimen || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Folfox protocol || Flavones || Resveratrol |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6762 | INHERITED FROM: manganese(III)-tetrakis(4-benzoic acid)porphyrin || Metalloporphyrins || Fluoroquinolones || Ciprofloxacin || cobaltiprotoporphyrin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || dieckol || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.7304 | INHERITED FROM: Benzimidazoles || Albendazole |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.7399 | INHERITED FROM: pomalidomide || GSK-J4 || Benzazepines || Aflatoxin M1 |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0.7523 | INHERITED FROM: Benzothiepins |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.7523 | INHERITED FROM: Benzimidazoles || Albendazole |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.8104 | INHERITED FROM: Genistein |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.8592 | INHERITED FROM: Vitamin E |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.8592 | INHERITED FROM: Tocopherols || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Quinazolines || Benzimidazoles || Isoquinolines || Chalcones || Heterocyclic Compounds, 4 or More Rings || Benzophenanthridines || Porphyrins || chrysin || Chlorpromazine || Isoindoles || Flavanones || Dactinomycin || kaempferol || Bucladesine || baicalein || Phenanthridines || Tetrapyrroles || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Phenothiazines || Carbazoles || Apigenin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Kaempferols || Flavones || Benzoxazines || Resveratrol || Benzodiazepines |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.8845 | INHERITED FROM: Flavanones || baicalein || baicalin |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.8953 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Benzimidazoles || indirubin-3'-monoxime || PP242 || Hemin || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || Caffeine |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0.9089 | INHERITED FROM: Indazoles || Benzydamine || senkirkine || Pyrrolizidine Alkaloids |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.9485 | INHERITED FROM: aflatoxin B2 |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0.9553 | INHERITED FROM: Cyclic AMP |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.964 | INHERITED FROM: Isoquinolines || Tubocurarine || Ro 15-4513 || Mivacurium || cisatracurium || Atracurium || cytisine || desformylflustrabromine || bretazenil || Dihydro-beta-Erythroidine || Quinolizines || Benzylisoquinolines || L 663581 || Bicuculline || Benzodiazepines |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: Lenalidomide || aflatoxin B2 || orantinib || Aripiprazole |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
54909,54909
54909 - Dimeric alpha+beta barrel
54909 - Dimeric alpha+beta barrel | 0 | Direct |
57196,56496
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | Direct |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49695,50370
49695 - gamma-Crystallin-like
50370 - Ricin B-like lectins | 0 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | Direct |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
51905,47576
51905 - FAD/NAD(P)-binding domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
47576,143575
47576 - Calponin-homology domain, CH-domain
143575 - GAS2 domain-like | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
56801,56801
56801 - Acetyl-CoA synthetase-like
56801 - Acetyl-CoA synthetase-like | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48371,49348
48371 - ARM repeat
49348 - Clathrin adaptor appendage domain | 0 | Direct |
52540,50729
52540 - P-loop containing nucleoside triphosphate hydrolases
50729 - PH domain-like | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
52087,48350
52087 - CRAL/TRIO domain
48350 - GTPase activation domain, GAP | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
48452,48403
48452 - TPR-like
48403 - Ankyrin repeat | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | Direct |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | Direct |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
82199,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | Direct |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54695,54695
54695 - POZ domain
54695 - POZ domain | 0 | Direct |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | Direct |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
46955,63763
46955 - Putative DNA-binding domain
63763 - SAND domain-like | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0 | Direct |
50249,46785
50249 - Nucleic acid-binding proteins
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
54277,50156
54277 - CAD & PB1 domains
50156 - PDZ domain-like | 0 | Direct |
47353,109640
47353 - Retrovirus capsid dimerization domain-like
109640 - KRAB domain (Kruppel-associated box) | 0 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
50370,57440
50370 - Ricin B-like lectins
57440 - Kringle-like | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
54416,54416
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region | 0 | Direct |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | Direct |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57440,56436
57440 - Kringle-like
56436 - C-type lectin-like | 0 | Direct |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | Direct |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
48452,48371
48452 - TPR-like
48371 - ARM repeat | 0 | Direct |
49299,49299
49299 - PKD domain
49299 - PKD domain | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
52540,90002
52540 - P-loop containing nucleoside triphosphate hydrolases
90002 - Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | Direct |
50729,50729
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
100895,48726
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | Direct |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | Direct |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | Direct |
54928,57756
54928 - RNA-binding domain, RBD
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
103657,48350
103657 - BAR/IMD domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
56496,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | Direct |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0 | Direct |
53300,69179
53300 - vWA-like
69179 - Integrin domains | 0 | Direct |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
57944,56436
57944 - Triple coiled coil domain of C-type lectins
56436 - C-type lectin-like | 0 | Direct |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
102848,54236
102848 - NSFL1 (p97 ATPase) cofactor p47, SEP domain
54236 - Ubiquitin-like | 0 | Direct |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | Direct |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | Direct |
81837,50978
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | Direct |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | Direct |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | Direct |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
54928,90209
54928 - RNA-binding domain, RBD
90209 - Ran binding protein zinc finger-like | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
50729,46785
50729 - PH domain-like
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
48371,101447
48371 - ARM repeat
101447 - Formin homology 2 domain (FH2 domain) | 0 | Direct |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
46579,64593
46579 - Prefoldin
64593 - Intermediate filament protein, coiled coil region | 0 | Direct |
48670,48097
48670 - Transducin (heterotrimeric G protein), gamma chain
48097 - Regulator of G-protein signaling, RGS | 0 | Direct |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
47113,-7
47113 - Histone-fold
-7 - CATH | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | Direct |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
81901,81901
81901 - HCP-like
81901 - HCP-like | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
50044,47769
50044 - SH3-domain
47769 - SAM/Pointed domain | 0 | Direct |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
57196,69687
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
57302,57302
57302 - Snake toxin-like
57302 - Snake toxin-like | 0 | Direct |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
54416,49998
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | Direct |
47473,57610
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
48452,81901
48452 - TPR-like
81901 - HCP-like | 0 | Direct |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
90193,90193
90193 - Notch domain
90193 - Notch domain | 0 | Direct |
57581,57581
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | Direct |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | Direct |
64593,90257
64593 - Intermediate filament protein, coiled coil region
90257 - Myosin rod fragments | 0 | Direct |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
90229,57850
90229 - CCCH zinc finger
57850 - RING/U-box | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49410,50242
49410 - Alpha-macroglobulin receptor domain
50242 - TIMP-like | 0 | Direct |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | Direct |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | Direct |
47576,140612
47576 - Calponin-homology domain, CH-domain
140612 - EB1 dimerisation domain-like | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.07594 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.1343 | Inherited |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.1515 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.2097 | Inherited |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0.2118 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.2118 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.3542 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.4271 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.4402 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4569 | Inherited |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.48 | Inherited |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.5917 | Inherited |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.6504 | Inherited |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.6689 | Inherited |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.672 | Inherited |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.672 | Inherited |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6762 | Inherited |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.7304 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.7399 | Inherited |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0.7523 | Inherited |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.7523 | Inherited |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.8104 | Inherited |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.8592 | Inherited |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.8592 | Inherited |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.8845 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.8953 | Inherited |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0.9089 | Inherited |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.9485 | Inherited |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0.9553 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.964 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
57184,57581,57184
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
75399,75399,75399
75399 - Plakin repeat
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
57184,57184,57581
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
50729,81837,50978
50729 - PH domain-like
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | DIRECT |
109640,57667,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
49299,49299,49299
49299 - PKD domain
49299 - PKD domain
49299 - PKD domain | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
49785,49899,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
103473,103473,141571
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter
141571 - Pentapeptide repeat-like | 0 | DIRECT |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49854,57535,49854
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
48403,48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
57184,57581,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | DIRECT |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
50729,57863,48403
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
81901,48452,48452
81901 - HCP-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
56496,49899,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
100895,47473,57610
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
48065,50729,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
56487,56487,56487
56487 - SRCR-like
56487 - SRCR-like
56487 - SRCR-like | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
49899,57196,56496
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57440,56436,56436
57440 - Kringle-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
54416,54416,49998
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | DIRECT |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
50156,50729,50729
50156 - PDZ domain-like
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
50370,57440,56436
50370 - Ricin B-like lectins
57440 - Kringle-like
56436 - C-type lectin-like | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
57184,100895,48726
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | DIRECT |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
50156,50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
57581,57184,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50978,50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,56496,49899
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.06592 | INHERITED FROM: napabucasin || Aflatoxin B1 |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.1451 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.5932 | INHERITED FROM: napabucasin || Quinazolines |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.672 | INHERITED FROM: Quinazolines || Pteridines || Lapatinib || Tyrphostins || Indazoles || Polyphenols || Quinolines || Aminoquinolines || Tetrahydrofolates || Formyltetrahydrofolates || Quinoxalines || CMF regimen || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Folfox protocol || Flavones || Resveratrol |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.7276 | INHERITED FROM: manganese(III)-tetrakis(4-benzoic acid)porphyrin || Metalloporphyrins || Fluoroquinolones || Ciprofloxacin || cobaltiprotoporphyrin || Tetrapyrroles || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || dieckol || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.7523 | INHERITED FROM: Benzimidazoles || Albendazole |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.8463 | INHERITED FROM: Isoquinolines || Thalidomide || Isoindoles || Phthalimides || Benzylisoquinolines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Benzoxazines |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.868 | INHERITED FROM: Lenalidomide || orantinib |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.9116 | INHERITED FROM: GSK-J4 || Benzazepines || Aflatoxin M1 |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
57184,57581,57184
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
75399,75399,75399
75399 - Plakin repeat
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
57184,57184,57581
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
50729,81837,50978
50729 - PH domain-like
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | Direct |
109640,57667,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
49299,49299,49299
49299 - PKD domain
49299 - PKD domain
49299 - PKD domain | 0 | Direct |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
49785,49899,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
103473,103473,141571
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter
141571 - Pentapeptide repeat-like | 0 | Direct |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
49854,57535,49854
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | Direct |
48403,48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
57184,57581,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | Direct |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
50729,57863,48403
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
81901,48452,48452
81901 - HCP-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
56496,49899,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
100895,47473,57610
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | Direct |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
48065,50729,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
56487,56487,56487
56487 - SRCR-like
56487 - SRCR-like
56487 - SRCR-like | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
49899,57196,56496
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57440,56436,56436
57440 - Kringle-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
54416,54416,49998
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | Direct |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
50156,50729,50729
50156 - PDZ domain-like
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
50370,57440,56436
50370 - Ricin B-like lectins
57440 - Kringle-like
56436 - C-type lectin-like | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
57184,100895,48726
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | Direct |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
50156,50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
57581,57184,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50978,50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,56496,49899
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.06592 | Inherited |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.1451 | Inherited |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.5932 | Inherited |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.672 | Inherited |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.7276 | Inherited |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.7523 | Inherited |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.8463 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.868 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.9116 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Heterocyclic Compounds, Fused-Ring
