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CTD Chemicals (CC): Heterocyclic Compounds 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
| Shortest distance to current term (+ for parents, - for children) |
CC term [CC ID] <#Children> |
#Domains (Superfamily|Family) |
#Supra-domain (Single|Duplex|Triple) |
| + 1: | Chemicals [MESH:D] <13> |
| 0: | Heterocyclic Compounds [MESH:D006571] <181> | (563|748) |
(566|486|238) |
| - 1: | Alkaloids [MESH:D000470] <1155> | (105|131) |
(112|95|49) |
| - 1: | Heterocyclic Compounds, 1-Ring [MESH:D006573] <233> | (504|683) |
(511|459|233) |
| - 1: | Heterocyclic Compounds, Bridged-Ring [MESH:D006572] <30> | (35|38) |
(37|13|3) |
| - 1: | Acids, Heterocyclic [MESH:D000147] <11> | (27|26) |
(27|15|7) |
| - 1: | Heterocyclic Oxides [MESH:D006577] <4> | (16|15) |
(16|5|4) |
| - 1: | Heterocyclic Compounds, Fused-Ring [MESH:D000072471] <3> | (463|624) |
(470|425|217) |
| - 1: | (1,4,7-tribenzyl-1,4,7-triazacyclononane-N,N',N'')(methylcyano)copper chlorate [MESH:C098528] | (0|0) |
(0|0|0) |
| - 1: | (1,4,7-triisopropyl-1,4,7-triazacyclonanane-N,N',N'')(methylcyano)copper trifluoromethylsulfonate [MESH:C098529] | (0|0) |
(0|0|0) |
| - 1: | (1-carboxyethyl-4,7-bis((6-carboxypyridin-2-yl)methyl)-1,4,7-triazacyclononane) [MESH:C545633] | (0|0) |
(0|0|0) |
| - 1: | (1-methylphosphonic-acid-4,7-bis((6-carboxypyridin-2-yl)methyl)-1,4,7-triazacyclononane) [MESH:C545632] | (0|0) |
(0|0|0) |
| - 1: | (2-(4,7-biscarboxymethyl(1,4,7)triazacyclonona-1-yl-ethyl)carbonylmethylamino)acetic acid [MESH:C529856] | (0|0) |
(0|0|0) |
| - 1: | (2-(4,7-biscarboxymethyl(1,4,7)triazacyclononan-1-ylethyl)carbonylmethylamino)acetic acid [MESH:C463502] | (0|0) |
(0|0|0) |
| - 1: | (3-(4,7-biscarboxymethyl(1,4,7)triazacyclononan-1-ylpropyl)carbonylmethylamino)acetic acid [MESH:C463519] | (0|0) |
(0|0|0) |
| - 1: | (4,7-bis-carboxymethyl-10-(2-aminoethyl)-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid [MESH:C511915] | (0|0) |
(0|0|0) |
| - 1: | 1,2,4-trioxane [MESH:C503429] | (0|0) |
(0|0|0) |
| - 1: | 1,3-dithiane [MESH:C012947] | (0|0) |
(0|0|0) |
| - 1: | 1,3-dithiolane [MESH:C012948] | (0|0) |
(0|0|0) |
| - 1: | 1,4,10,13-tetraoxa-7,16-diaza-cycloctadecane [MESH:C507685] | (0|0) |
(0|0|0) |
| - 1: | 1,4,7,10-tetraazacyclododecane-N,N',N''N'''-etraacetic acid-lys(8)-vasotocin [MESH:C428503] | (0|0) |
(0|0|0) |
| - 1: | 1,4,7-triazacyclononane [MESH:C075712] | (0|0) |
(0|0|0) |
| - 1: | 1,4,7-triazacyclononane-1,4,7-tris-(glutaric acid) [MESH:C581281] | (0|0) |
(0|0|0) |
| - 1: | 1,4,7-triazacyclononane-1,4-diacetate [MESH:C519451] | (0|0) |
(0|0|0) |
| - 1: | 1,4-dithiane [MESH:C060568] | (0|0) |
(0|0|0) |
| - 1: | 1,5-dioxaspiro(3.2)hexane [MESH:C458142] | (0|0) |
(0|0|0) |
| - 1: | 1,5-dioxepan-2-one [MESH:C091881] | (0|0) |
(0|0|0) |
| - 1: | 1,7-dimethyl-1,4,7,10-tetraazacyclododecane [MESH:C512308] | (0|0) |
(0|0|0) |
| - 1: | 1-(2-guanidinoethyl)-4-(2-hydroxyethyl)-1,4,7-triazacyclononane hydrochloride [MESH:C518837] | (0|0) |
(0|0|0) |
| - 1: | 1-(2-hydroxyphenyl)-2-(2-pyridylmethyl)-4-(hydroxyimino)-2-azapentane [MESH:C545634] | (0|0) |
(0|0|0) |
| - 1: | 1-(3-aminopropyl)-4-methyl-1,4,8,11-tetraazacyclotetradecane [MESH:C054749] | (0|0) |
(0|0|0) |
| - 1: | 1-(4-fluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)cinnoline-3-carboxylic acid [MESH:C061722] | (0|0) |
(0|0|0) |
| - 1: | 1-(phenylmethyl)-4,7,10-tris((4'-methylphenyl)sulfonyl)-1,4,7,10-tetraazacyclododecane [MESH:C105767] | (0|0) |
(0|0|0) |
| - 1: | 1-acetato-1,4,7-triazacyclononane [MESH:C096683] | (0|0) |
(0|0|0) |
| - 1: | 1-ethylphenoxathiin 10,10-dioxide [MESH:C076100] | (0|0) |
(0|0|0) |
| - 1: | 1-methyl-2-thietaniumcarboxylic acid [MESH:C114290] | (0|0) |
(0|0|0) |
| - 1: | 12(4-nitrobenzyl)-1,4,7,10-tetraazacyclotridecane-1,4,7-triacetic acid [MESH:C069409] | (0|0) |
(0|0|0) |
| - 1: | 12-(4-nitrobenzyl)-1,4,7,10-tetraazacyclotridecane-1,4,7,10-tetraacetic acid [MESH:C069408] | (0|0) |
(0|0|0) |
| - 1: | 2,2-dichloro-1,3-dithiacyclobutanone [MESH:C012893] | (0|0) |
(0|0|0) |
| - 1: | 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaaza-isowurtzitane [MESH:C482139] | (0|0) |
(0|0|0) |
| - 1: | 2,4,6-triphenylverdazyl [MESH:C057661] | (0|0) |
(0|0|0) |
| - 1: | 2,5-dihydroxy-1,4-dithiane [MESH:C064095] | (0|0) |
(0|0|0) |
| - 1: | 2,6-epoxyazocane [MESH:C000599345] | (0|0) |
(0|0|0) |
| - 1: | 2-(4-isothiocyanatobenzyl)-1,4,7,10--tetraaza-1,4,7,10-tetra-(2-carbamoylmethyl)cyclododecane [MESH:C410212] | (0|0) |
(0|0|0) |
| - 1: | 2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid [MESH:C087160] | (0|0) |
(0|0|0) |
| - 1: | 2-(4-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid [MESH:C082060] | (0|0) |
(0|0|0) |
| - 1: | 2-(4-nitrobenzyl)-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid [MESH:C078688] | (0|0) |
(0|0|0) |
| - 1: | 2-vinyl-4H-1,3-dithiin [MESH:C075381] | (0|0) |
(0|0|0) |
| - 1: | 3,3'-(1,2,4,5-tetrazine-3,6-diyl)dibenzoic acid [MESH:C582762] | (0|0) |
(0|0|0) |
| - 1: | 3,4-9,10-13,14-tribenzo-1,12-diaza-5,8-dioxacyclotetradecane-1,11-diene [MESH:C000611346] | (0|0) |
(0|0|0) |
| - 1: | 3,7-bis(3-trifluoromethylphenyl)-1,5,3,7-dioxadiazocane [MESH:C093077] | (0|0) |
(0|0|0) |
| - 1: | 3,7-bis-(4-trifluoromethylphenyl)-1,5,3,7-dioxadiazocane [MESH:C065415] | (0|0) |
(0|0|0) |
| - 1: | 3-(3-aminopropoxy)-1,5,9-triazacyclododecane [MESH:C110950] | (0|0) |
(0|0|0) |
| - 1: | 3-(3-aminopropyl)-1,5,9-triazacyclododecane [MESH:C110949] | (0|0) |
(0|0|0) |
| - 1: | 3-(N-(4-pyridino)carbamoyl)methyl-3,4,4-trimethyl-1,2-dioxetane [MESH:C052793] | (0|0) |
(0|0|0) |
| - 1: | 3-decyl-1,5,8-triazacyclodecane-2,4-dione [MESH:C091054] | (0|0) |
(0|0|0) |
| - 1: | 3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane [MESH:C103833] | (0|0) |
(0|0|0) |
| - 1: | 3-vinyl-4H-1,2-dithiin [MESH:C075382] | (0|0) |
(0|0|0) |
| - 1: | 4,5-dihydroxy-1,2-dithiane [MESH:C060456] | (0|0) |
(0|0|0) |
| - 1: | 4,8,11-trimethyl-1,4,8,11-tetraazacyclotetradecane-1-acetate [MESH:C522823] | (0|0) |
(0|0|0) |
| - 1: | 4-((1,4,8,11-tetraazacyclotetradec-1-yl)methyl)benzoic acid [MESH:C074011] | (0|0) |
(0|0|0) |
| - 1: | 4-aminophenylethyl-1,4,7,10-tetraazacyclodecane-N,N',N'',N'''-tetraacetic acid [MESH:C085738] | (0|0) |
(0|0|0) |
| - 1: | 4-bromoacetamidobenzyl-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid [MESH:C063627] | (0|0) |
(0|0|0) |
| - 1: | 4-hydroxymethyl-3,3,4-trimethyl-1,2-dioxetane [MESH:C052792] | (0|0) |
(0|0|0) |
| - 1: | 4-methoxyphenyl-1,3-dithiolane [MESH:C063036] | (0|0) |
(0|0|0) |
| - 1: | 4-n-dodecylphenyl compound [MESH:C114653] | (0|0) |
(0|0|0) |
| - 1: | 4-n-heptylphenyl compound [MESH:C114652] | (0|0) |
(0|0|0) |
| - 1: | 5,7,12,14-tetramethyldibenzo(b,i)(1,4,8,11)tetraazacyclotetradecahexenate [MESH:C110688] | (0|0) |
(0|0|0) |
| - 1: | 6-(4-bromoacetamidobenzyl)-1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid [MESH:C046529] | (0|0) |
(0|0|0) |
| - 1: | 6-(4-methoxyphenyl)-2,4-diphenylverdazyl [MESH:C057662] | (0|0) |
(0|0|0) |
| - 1: | 6-(4-nitrophenyl)-2,4-diphenylverdazyl [MESH:C057663] | (0|0) |
(0|0|0) |
| - 1: | 6-methyl-8-methylsulfonyl-1,3,4,6-tetrahydro-2H-5,1-benzothiazocine [MESH:C048443] | (0|0) |
(0|0|0) |
| - 1: | 6pi-2-azatriene [MESH:C519122] | (0|0) |
(0|0|0) |
| - 1: | 7-((dimethylphenyl)silyl)-2-oxo-6-(2-phenylcyclohexyloxy)-2a,3,6,7,7a,7b-hexahydro-2H-1,4,5-trioxa-4 [MESH:C104203] | (0|0) |
(0|0|0) |
| - 1: | 9-benzyl-3-methylene-1,5-di-p-toluenesulfonyl-1,5,9-triazacyclododeane [MESH:C498074] | (0|0) |
(0|0|0) |
| - 1: | 9-methyl-8-phenyl-6-((2-phenylcyclohexyl)oxy)-4-aza-3,5-dioxatricyclo(5.2.1.0(4,9))decane [MESH:C104204] | (0|0) |
(0|0|0) |
| - 1: | 94-126 compound [MESH:C400540] | (0|0) |
(0|0|0) |
| - 1: | 95-588 compound [MESH:C400539] | (0|0) |
(0|0|0) |
| - 1: | 99-411 compound [MESH:C529215] | (0|0) |
(0|0|0) |
| - 1: | AR C117977 [MESH:C525748] | (0|0) |
(0|0|0) |
| - 1: | AS 186c [MESH:C086149] | (0|0) |
(0|0|0) |
| - 1: | AS 186d [MESH:C086150] | (0|0) |
(0|0|0) |
| - 1: | BMS-986165 [MESH:C000628674] | (0|0) |
(0|0|0) |
| - 1: | CT 77 [MESH:C088193] | (0|0) |
(0|0|0) |
| - 1: | CX157 [MESH:C551866] | (0|0) |
(0|0|0) |
| - 1: | Crismel [MESH:C020876] | (0|0) |
(0|0|0) |
| - 1: | DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide [MESH:C083918] | (0|0) |
(0|0|0) |
| - 1: | FR 134043 [MESH:C094461] | (0|0) |
(0|0|0) |
| - 1: | FR177391 [MESH:C508031] | (0|0) |
(0|0|0) |
| - 1: | Galbulimima alkaloid 13 [MESH:C518378] | (0|0) |
(0|0|0) |
| - 1: | Gd-MCTA [MESH:C067087] | (0|0) |
(0|0|0) |
| - 1: | Genivir [MESH:C069663] | (0|0) |
(0|0|0) |
| - 1: | JM 2763 [MESH:C097727] | (0|0) |
(0|0|0) |
| - 1: | JSTX-3 [MESH:C426070] | (0|0) |
(0|0|0) |
| - 1: | N',N',N'-tris(2-methyl-2-mercaptopropyl)-1,4,7-triazacyclononane [MESH:C108490] | (0|0) |
(0|0|0) |
| - 1: | N,N',N'',N'''-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane [MESH:C082033] | (0|0) |
(0|0|0) |
| - 1: | N,N',N''-tris(2-methyl-(2-mercaptopropyl))-1,4,7-triazacyclononane-pertechnetate [MESH:C075711] | (0|0) |
(0|0|0) |
| - 1: | N,N',N''-tris(2-methyl-(2-propanethiol))-1,4,7-triazacyclononane [MESH:C080232] | (0|0) |
(0|0|0) |
| - 1: | N-benzyl-3,11-azatricyclo(6.3.0.0(2,6))undecane [MESH:C103010] | (0|0) |
(0|0|0) |
| - 1: | N-nitrosodithiazine [MESH:C055148] | (0|0) |
(0|0|0) |
| - 1: | N-octyl-3,11-azatricyclo(6.3.0.0(2,6))undecane [MESH:C103011] | (0|0) |
(0|0|0) |
| - 1: | NSTX-3 [MESH:C426071] | (0|0) |
(0|0|0) |
| - 1: | RAP polymer [MESH:C577040] | (0|0) |
(0|0|0) |
| - 1: | RD3 0028 [MESH:C119093] | (0|0) |
(0|0|0) |
| - 1: | Ro 48-3656 [MESH:C110992] | (0|0) |
(0|0|0) |
| - 1: | SID 791 [MESH:C097728] | (0|0) |
(0|0|0) |
| - 1: | TD-2749 [MESH:C576926] | (0|0) |
(0|0|0) |
| - 1: | YM-96765 [MESH:C502178] | (0|0) |
(0|0|0) |
| - 1: | acutiphycin [MESH:C515767] | (0|0) |
(0|0|0) |
| - 1: | adroxazine [MESH:C045437] | (0|0) |
(0|0|0) |
| - 1: | carbabenzpyride [MESH:C079927] | (0|0) |
(0|0|0) |
| - 1: | contrast agent P792 [MESH:C435266] | (0|0) |
(0|0|0) |
| - 1: | copper acetamidobenzyl-1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid-serum albumi [MESH:C067800] | (0|0) |
(0|0|0) |
| - 1: | copper(II)-1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid [MESH:C113624] | (0|0) |
(0|0|0) |
| - 1: | copper-67-2IT-BAT-Lym-1 [MESH:C097568] | (0|0) |
(0|0|0) |
| - 1: | corrigendum compound [MESH:C062540] | (0|0) |
(0|0|0) |
| - 1: | cyclam [MESH:C024560] | (0|0) |
(0|0|0) |
| - 1: | cyclen [MESH:C038072] | (0|0) |
(0|0|0) |
| - 1: | deoxocarbaqinghaosu [MESH:C071629] | (0|0) |
(0|0|0) |
| - 1: | desoxymorellin [MESH:C482270] | (0|0) |
(0|0|0) |
| - 1: | diamsar chelate [MESH:C059143] | (0|0) |
(0|0|0) |
| - 1: | dichloro(triazacyclononane)copper(II) [MESH:C427213] | (0|0) |
(0|0|0) |
| - 1: | dimethyldioxetanone [MESH:C015832] | (0|0) |
(0|0|0) |
| - 1: | dioxocyclam [MESH:C034036] | (0|0) |
(0|0|0) |
| - 1: | dithietane-1,3-dioxide [MESH:C445704] | (0|0) |
(0|0|0) |
| - 1: | flufenzine [MESH:C417227] | (0|0) |
(0|0|0) |
| - 1: | flurenizid [MESH:C065925] | (0|0) |
(0|0|0) |
| - 1: | forbesione [MESH:C482271] | (0|0) |
(0|0|0) |
| - 1: | frankiamide [MESH:C431244] | (0|0) |
(0|0|0) |
| - 1: | gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate [MESH:C050823] | (0|0) |
(0|0|0) |
| - 1: | gadolinium Cy(2)DOTA [MESH:C094044] | (0|0) |
(0|0|0) |
| - 1: | gadolinium DOTA meglumine [MESH:C112669] | (0|0) |
(0|0|0) |
| - 1: | gadoteridol [MESH:C062402] | (0|0) |
(0|0|0) |
| - 1: | gallium 1,4,7-triazacyclononane-N,N',N''-tris(methylenephosphonic acid) [MESH:C402168] | (0|0) |
(0|0|0) |
| - 1: | hexanal-1,3-dithiane [MESH:C077043] | (0|0) |
(0|0|0) |
| - 1: | hexatroxanone [MESH:C061890] | (0|0) |
(0|0|0) |
| - 1: | himgaline [MESH:C518376] | (0|0) |
(0|0|0) |
| - 1: | hopromalinol [MESH:C578828] | (0|0) |
(0|0|0) |
| - 1: | hoprominol [MESH:C578827] | (0|0) |
(0|0|0) |
| - 1: | indium 111-DOTA-lanreotide [MESH:C116409] | (0|0) |
(0|0|0) |
| - 1: | indium-111-DOTA-peptide chimeric L6 [MESH:C407040] | (0|0) |
(0|0|0) |
| - 1: | kevloc [MESH:C112072] | (0|0) |
(0|0|0) |
| - 1: | lansamide-2 [MESH:C503446] | (0|0) |
(0|0|0) |
| - 1: | lead-203 DOTA-B72.3 [MESH:C113007] | (0|0) |
(0|0|0) |
| - 1: | lipogrammistin A [MESH:C122196] | (0|0) |
(0|0|0) |
| - 1: | macrocycle 1 [MESH:C106058] | (0|0) |
(0|0|0) |
| - 1: | macrosphelide A [MESH:C097798] | (0|0) |
(0|0|0) |
| - 1: | macrosphelide B [MESH:C097799] | (0|0) |
(0|0|0) |
| - 1: | mesulfen [MESH:C011911] | (0|0) |
(0|0|0) |
| - 1: | mustelan [MESH:C013141] | (0|0) |
(0|0|0) |
| - 1: | octahydro-9-hydroxyethyl-1-methoxy-3,4,4-trimethyl-1H-3,9a-peroxy-2-benzoxepin [MESH:C087349] | (0|0) |
(0|0|0) |
| - 1: | pentatroxane [MESH:C061889] | (0|0) |
(0|0|0) |
| - 1: | phenoxathiin [MESH:C068135] | (0|0) |
(0|0|0) |
| - 1: | plerixafor octahydrochloride [MESH:C088327] | (0|0) |
(0|0|0) |
| - 1: | polylysine-(Gd-DOTA) [MESH:C069063] | (0|0) |
(0|0|0) |
| - 1: | pteriatoxin A [MESH:C523038] | (0|0) |
(0|0|0) |
| - 1: | pteriatoxin B [MESH:C523040] | (0|0) |
(0|0|0) |
| - 1: | pteriatoxin C [MESH:C523039] | (0|0) |
(0|0|0) |
| - 1: | pyrenophorol [MESH:C509954] | (0|0) |
(0|0|0) |
| - 1: | s-trioxane [MESH:C011374] | (0|0) |
(0|0|0) |
| - 1: | sar chelate [MESH:C059142] | (0|0) |
(0|0|0) |
| - 1: | sekothrixide [MESH:C072162] | (0|0) |
(0|0|0) |
| - 1: | setosol [MESH:C092938] | (0|0) |
(0|0|0) |
| - 1: | south 7 [MESH:C505700] | (0|0) |
(0|0|0) |
| - 1: | spirotenuipesine A [MESH:C483569] | (0|0) |
(0|0|0) |
| - 1: | spirotenuipesine B [MESH:C483570] | (0|0) |
(0|0|0) |
| - 1: | ternelin [MESH:C000600911] | (0|0) |
(0|0|0) |
| - 1: | tetraaza(1.1.1.1)cyclophane [MESH:C000610131] | (0|0) |
(0|0|0) |
| - 1: | tetraaza-14-crown-4 [MESH:C509110] | (0|0) |
(0|0|0) |
| - 1: | tetraformaltrisazine [MESH:C048247] | (0|0) |
(0|0|0) |
| - 1: | tetrathiafulvalene [MESH:C063887] | (0|0) |
(0|0|0) |
| - 1: | tetravinyl-tetramethylcyclo-tetrasiloxane [MESH:C110979] | (0|0) |
(0|0|0) |
| - 1: | thiahexatroxane [MESH:C061891] | (0|0) |
(0|0|0) |
| - 1: | thianthrene [MESH:C009449] | (0|0) |
(0|0|0) |
| - 1: | thiirancarboxylic acid [MESH:C419887] | (0|0) |
(0|0|0) |
| - 1: | treloxinate [MESH:C002236] | (0|0) |
(0|0|0) |
| - 1: | tris(o-phenylenedioxy)cyclotriphosphazene [MESH:C528765] | (0|0) |
(0|0|0) |
| - 1: | tulathromycin [MESH:C485204] | (0|0) |
(0|0|0) |
| - 1: | vermixocin A [MESH:C077329] | (0|0) |
(0|0|0) |
| - 1: | yttrium 90-DOTA-lanreotide [MESH:C116408] | (0|0) |
(0|0|0) |
| - 1: | yttrium(III)-1,4,7,10-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid [MESH:C113625] | (0|0) |
(0|0|0) |
| - 1: | yttrium-90-DOTA-peptide-chimeric L6 [MESH:C112391] | (0|0) |
(0|0|0) |
| - 1: | zinc xylyl-bicyclam [MESH:C464969] | (0|0) |
(0|0|0) |
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| FAH | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| YjeF N-terminal domain-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Lipoxigenase | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Pseudouridine synthase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| FnI-like domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Phenylalanine zipper | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| GAF domain-like | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| FKBP-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| SCOP hierarchy in SUPERFAMILY | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| HIN-2000 domain-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Probable bacterial effector-binding domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Pentapeptide repeat-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| GTPase activation domain, GAP | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Uteroglobin-like | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Triple coiled coil domain of C-type lectins | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Hermes dimerisation domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| PH domain-like | 0.00001007 | DIRECT |
| SH3-domain | 0.004463 | INHERITED FROM: Pyridazines || aflatoxin B2 || ponatinib || Azoles || AG 1879 |
| Protein kinase-like (PK-like) | 0.005743 | INHERITED FROM: Imatinib Mesylate || SU 5402 || PI 620 || Flavones || Anthocyanins || NVP-TAE684 || labedipinedilol A || ZSTK474 || bisindolylmaleimide || staurosporine aglycone || BMS 754807 || dihydromyricetin || Xanthenes || Isoindoles || Benzodioxoles || PD 173074 || WY-135 || Cyclic GMP || ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate || Pyridazines || orantinib || indole-5-carboxamide || Cantharidin || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || baohuoside I || baricitinib || Semaxinib || GSK2141795 || 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbo || AG-012986 || Heterocyclic Compounds, 3-Ring || Naphthyridines || Phenazines || dracorhodin || Camptothecin || SU 6656 || aucubin || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Dasatinib || 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine || Dioxolanes || Coumarins || Niacinamide || Ochratoxins || GSK2110183 || 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine || 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione || Benzothiazoles || rutacarpine || Orotic Acid || Pyrans || fumosorinone || tanespimycin || Sterigmatocystin || Y 27632 || aflatoxin B2 || alvocidib || Morpholines || 5-iodo-3-(2-azetidinylmethoxy)pyridine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Lactams || Polyphenols || Pyrazines || 5-iodotubercidin || ponatinib || bisindolylmaleimide I || WHI P154 || deguelin || Quinoxalines || Tocopherols || ML 9 || Chromones || GSK 1363089 || Alkaloids || Pyrimidines || dehydroglyasperin C || NVP ADW742 || dictamnine || Azoles || 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione || 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone || ON123300 || Indazoles || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || 4-acetylantroquinonol B || 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide || Quinolines || N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3- || Imidazoles || 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine || 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone || 103D5R || Pyridones || Acids, Heterocyclic || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide || pifithrin || 6-(methylamino)pyrido(3,4-d)pyrimidine || esculetin || Indoles || Isoquinolines || AG 1879 || Pyrroles || Adenosine Diphosphate || 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione || Dioxoles || Oxazines || A 419259 || Benzopyrans || Indolizines || Tubercidin || Celecoxib || tylophorine || N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide || quercetin 4'-O-glucopyranoside || ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate || APS-2-79 || Nicotinic Acids || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || Piperazines || Quinazolines || Pyocyanine || Folfox protocol || 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol || Win 55212-2 || Maleimides || napabucasin || Benzimidazoles || NVP-AEW541 || Sorafenib || Capsaicin || Iridoid Glycosides || Staurosporine || Pyridines || 6,7-dimethoxy-3-phenylquinoxaline || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Carbazoles || norcantharidin || trametinib || Rimonabant || Thiazoles || rottlerin || didymin || Lactams, Macrocyclic || 1',2'-dihydrorotenone || Maytansine || Solanaceous Alkaloids || coptisine || 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy || fascaplysine || copper-1,10-phenanthroline || Piperidines || Sunitinib |
| P-loop containing nucleoside triphosphate hydrolases | 0.008148 | INHERITED FROM: calcein AM || Furans || fluorexon || 2,3-bis(3'-hydroxybenzyl)butyrolactone || Thioxanthenes || Vinca Alkaloids || Dioxolanes || macitentan || Pyrans || Risedronic Acid || mesaconitine || AC 93253 || Coumestrol || Tolvaptan || 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)a || Phosphoadenosine Phosphosulfate || 4-Butyrolactone || bisbenzimide ethoxide trihydrochloride || benzoylhypaconine || Thiazines || TAK-875 || Elacridar || verlukast || pitavastatin |
| FYVE/PHD zinc finger | 0.01199 | INHERITED FROM: 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide || Dioxoles |
| EGF/Laminin | 0.01457 | INHERITED FROM: NVP-TAE684 || GSK1210151A || Propylthiouracil || Tetrachlorodibenzodioxin || dorsomorphin || Heterocyclic Compounds, 3-Ring || Dasatinib || 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine || aflatoxin B2 || Quinoxalines || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Imidazoles || Dioxoles || batimastat || Cytidine || Heterocyclic Oxides || Pyridines || Cyclic S-Oxides || Aminopyridines || Thiazoles |
| RNA-binding domain, RBD | 0.01726 | INHERITED FROM: pateamine A || Pyrazoles || Vitamin E || Vinca Alkaloids || ((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one) || PP242 || ICG 001 || yessotoxin |
| SH2 domain | 0.02702 | INHERITED FROM: Imatinib Mesylate || N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || stattic || Methylthiouracil || 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester || Pyridazines || baricitinib || tofacitinib || 4'-methoxy licoflavanone || Heterocyclic Compounds, 3-Ring || Dasatinib || Niacinamide || Azepines || Polyphenols || WP1066 || ponatinib || Azoles || 4-acetylantroquinonol B || N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidine || INCB018424 || alpinumisoflavone || Imidazoles || (+)-JQ1 compound || AG 1879 || isoquercitrin || Triazoles || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || AZD 1480 || norcantharidin |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.02882 | INHERITED FROM: Benzoxazines || Aminoacridines || 2-methyl-c-5-(4-(5-methyl-2-(4-methylphenyl)-4-oxazolyl)butyl)-1,3-dioxane-r-2-carboxylic acid || laurolactam || 1,4-dihydropyridine || cilnidipine || biochanin A || Nebivolol || fenpyroximate || iprodione || Oxazoles || Ro 41-5253 || enilconazole || Pyridazines || pomiferin || terbutylazine || 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine || Benzothiepins || pyridaben || pazopanib || Ciclopirox || quinoxyfen || Pyrimethamine || osajin || Thiazepines || Dronedarone || Pyrans || 4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid || Heterocyclic Compounds, 4 or More Rings || Adenine Nucleotides || 1,4-bis(2-(3,5-dichloropyridyloxy))benzene || isoprothiolane || fenarimol || 2-acetylphenothiazine || Emetine || galaxolide || prochloraz || Benomyl || metoprine || Pyrimidines || Acridines || Azoles || muraglitazar || Proflavine || Silybin || Quinolines || lacidipine || GKT137831 || 1,5-benzothiazepine || Isoquinolines || ZK 216348 || Flavonoids || Dioxoles || kaempferol || Azetines || TRAM 34 || propiconazole || Reserpine || Purine Nucleotides || tegaserod || fludioxonil || Dihydropyridines || cerivastatin || icaritin || flavone || norathyriol || GW 501516 || vinclozolin || chlormidazole || 3-methylquercetin || Staurosporine || Pyridines || piperophos || Trifluridine || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || rubitecan || pitavastatin || triflumizol || Thiazoles || ST 1481 || LY 518674 || cyprodinil || irilone || daidzein || Kaempferols |
| Ubiquitin-like | 0.04324 | INHERITED FROM: ZSTK474 || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| ARM repeat | 0.05683 | INHERITED FROM: ZSTK474 || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| Cysteine proteinases | 0.06643 | INHERITED FROM: benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide |
| beta-beta-alpha zinc fingers | 0.07353 | INHERITED FROM: GSK-J4 || Leflunomide || Benzazepines || pomalidomide || Aflatoxin M1 || Isoxazoles |
| NAD(P)-binding Rossmann-fold domains | 0.0975 | INHERITED FROM: NAD || Oxcarbazepine || Cimetidine || K 7174 || Adenine Nucleotides || Fomepizole || GW 4064 || Isatin || Metyrapone || Dioxins || Purine Nucleotides || fipronil || Purines || NADP |
| Galactose-binding domain-like | 0.1013 | INHERITED FROM: Pyridazines || ponatinib |
| Nucleic acid-binding proteins | 0.1048 | INHERITED FROM: Piroxicam || Furans || Coumarins || 4-Butyrolactone || Tunicamycin || Thiazines || Chromans || cryptolepine |
| E set domains | 0.1402 | INHERITED FROM: piperine || scoparone || Benzoxazoles || Carbolines || Calcimycin || Harmala Alkaloids |
| Growth factor receptor domain | 0.1928 | INHERITED FROM: Flavones || NVP-TAE684 || baicalin || dorsomorphin || Heterocyclic Compounds, 3-Ring || Troglitazone || Dasatinib || Pteridines || CMF regimen || ponatinib || Formyltetrahydrofolates || Pyrimidines || Azoles || Imidazoles || 6-(methylamino)pyrido(3,4-d)pyrimidine || Canertinib || Dioxoles || Quinazolines || Folfox protocol || napabucasin || NVP-AEW541 || Heterocyclic Oxides || Pyridines || Cyclic S-Oxides || Thiazoles |
| FAD/NAD(P)-binding domain | 0.2005 | INHERITED FROM: Methimazole || Thioctic Acid || Purine Nucleosides || senkirkine || Azoles || Indazoles || Benzydamine || Pyrrolizidine Alkaloids |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.204 | INHERITED FROM: ZSTK474 || Pyrans || aflatoxin B2 || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide |
| (Trans)glycosidases | 0.2073 | INHERITED FROM: Oxocins || PP242 || yessotoxin |
| Mitochondrial carrier | 0.2143 | INHERITED FROM: Adenosine Triphosphate || Tunicamycin || Atrazine || Triazines || Thymidine |
| SMAD/FHA domain | 0.2214 | INHERITED FROM: fludarabine || LDN 193189 || aucubin || Cytochalasin D || Vidarabine || LY2109761 || INCB018424 || Iridoids || casticin || Iridoid Glucosides || Iridoid Glycosides || osthol || Cytochalasins || galangin |
| Leucine zipper domain | 0.2214 | INHERITED FROM: Citrinin || piperine || Phenanthrolines || 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)am || Penicillins || Phthalimides || Isoindoles || Benzodioxoles || cylindrospermopsin || Oxazoles || dinophysistoxin 1 || Tetrachlorodibenzodioxin || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Heterocyclic Compounds, 3-Ring || Phenobarbital || quinomethionate || Vinca Alkaloids || Pteridines || Leflunomide || Ochratoxins || Heterocyclic Compounds, 4 or More Rings || Uric Acid || Azepines || Carbamazepine || Pyrazines || NSC668394 || SR 144528 || Quinoxalines || Nifedipine || sauchinone || Penicillin G || alpha-Tocopherol || SB 203580 || Cyclic AMP || Quinolines || Dioxins || BIX 02189 || Pyrrolidines || Acids, Heterocyclic || Pyrimidine Nucleosides || Isoquinolines || Flavonoids || Dioxoles || nefazodone || Oxazines || Anisomycin || Cocaine || Benzofurans || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Hemin || Piperazines || Quinazolines || CP 31398 || 9-methoxycamptothecin || Aminopterin || 4-Quinolones || Indole Alkaloids || O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate || fisetin || Pyridines || Isoxazoles || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Rimonabant || Quercetin || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || Tetrazoles || rottlerin || Pyrazinamide || Tropanes || Piperidines || Tetrapyrroles |
| PX domain | 0.2288 | INHERITED FROM: Go 6976 |
| Cadherin-like | 0.2428 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
| Fibronectin type III | 0.2443 | INHERITED FROM: dorsomorphin || aflatoxin B2 || ponatinib || Dioxoles || Panobinostat || Cytidine || Pyridines || Aminopyridines |
| SET domain | 0.2701 | INHERITED FROM: Benzylisoquinolines || Berberine || Isoquinolines || Berberine Alkaloids |
| Interleukin 8-like chemokines | 0.2879 | INHERITED FROM: Imatinib Mesylate || Propidium || fexofenadine || Demecolcine || Flavones || Hesperidin || 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || palmatine || Phenanthridines || 1-carboxyheptylimidazole || pevonedistat || Ritonavir || 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || tofacitinib || Oxypurinol || Itraconazole || PD168393 || Vinca Alkaloids || Troglitazone || Dasatinib || Pteridines || Secologanin Tryptamine Alkaloids || Benzoxazoles || Terfenadine || Morphine Derivatives || Oxazolone || Morphinans || Polyphenols || BIRB 796 || Calcimycin || Pterins || roflumilast N-oxide || Emetine || Quinolones || SB 203580 || Opiate Alkaloids || Quinolines || Deoxycytidine || Imidazoles || Roflumilast || Pyrrolidines || gemcitabine || Albendazole || Quinolinium Compounds || Azabicyclo Compounds || Cocaine || 3'-methoxy-4'-nitroflavone || Dequalinium || captax || coralyne || Telmisartan || Rutin || Puromycin || Piperazines || Aminopterin || E804 bisindole || luliconazole || 2-methyl-4-isothiazolin-3-one || 6-formylindolo(3,2-b)carbazole || Benzimidazoles || amorolfine || Lopinavir || Allopurinol || Colchicine || Aripiprazole || Thiazoles || Tropanes || Piperidines |
| p53-like transcription factors | 0.2973 | INHERITED FROM: piperine || Imatinib Mesylate || pyrrolidine dithiocarbamic acid || Flavones || Anthocyanins || Isoindoles || Benzodioxoles || Thioctic Acid || Umbelliferones || pevonedistat || Ritonavir || tofacitinib || 4'-methoxy licoflavanone || Imidazolidines || Vinca Alkaloids || Flavanones || Thiouracil || scoparone || Niacinamide || Benzothiazoles || Resveratrol || Benzoxazoles || Y 27632 || Morpholines || Azepines || SRT2183 || Carbolines || Terfenadine || Polyphenols || Calcimycin || bisindolylmaleimide I || Harmala Alkaloids || Nitrofurans || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Dicumarol || INCB018424 || alpinumisoflavone || Acids, Heterocyclic || Luteolin || Ergolines || Ellagic Acid || esculetin || AG 1879 || isoquercitrin || Imidazolines || Piperazines || Benzodiazepinones || Dactinomycin || piperlonguminine || calyculin A || goniothalamin || chrysin || Ergot Alkaloids || Triazoles || fisetin || Nicotine || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Staurosporine || Apigenin || AZD 1480 || myricetin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbazoles || Pergolide || alpha-naphthoflavone || norcantharidin || Cytochalasins || Morphine || Thiazoles || Tetrazoles || Piperidines || Kaempferols |
| PLP-dependent transferases | 0.3174 | INHERITED FROM: Tetrachlorodibenzodioxin || K 7174 || Picolines || Dioxins || Vitamin B 6 |
| (Phosphotyrosine protein) phosphatases II | 0.3296 | INHERITED FROM: Leflunomide |
| Thioredoxin-like | 0.3481 | INHERITED FROM: Bile Pigments || Cinchona Alkaloids || desethylamodiaquine || Thioctic Acid || dinophysistoxin 1 || Chlorophyllides || Paraquat || fluazinam || xanthohumol || Kathon 930 || captafol || Nevirapine || 2-n-octyl-4-isothiazolin-3-one || amodiaquine quinoneimine || Captan || triflumizol || Amodiaquine || KT 5720 || Quinidine || Tetrapyrroles |
| Periplasmic binding protein-like I | 0.3481 | INHERITED FROM: Citalopram |
| DBL homology domain (DH-domain) | 0.3513 | INHERITED FROM: aflatoxin B2 || Aminopyridines |
| MHC antigen-recognition domain | 0.3595 | INHERITED FROM: valdecoxib || Ketorolac || beta-Lactams || Lincosamides || Chlorothiazide || Lactams || entinostat || Penicillin G || Quinolines || Ampicillin || Diltiazem || Gefitinib || Benzothiadiazines || Thiazines || Quinazolines || Heterocyclic Oxides || Cyclic S-Oxides || MRK 003 || Omeprazole || Cephalosporins |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.3675 | INHERITED FROM: cylindrospermopsin || procyanidin B2 || S-Adenosylmethionine |
| vWA-like | 0.3793 | INHERITED FROM: Atorvastatin || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Phenytoin |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3825 | INHERITED FROM: stattic || EGFR tyrosine kinase inhibitor 324674 || Hydralazine || Phthalazines || Heterocyclic Oxides || Cyclic S-Oxides |
| Fibrinogen C-terminal domain-like | 0.4206 | INHERITED FROM: Adenosine Diphosphate |
| Alkaline phosphatase-like | 0.4333 | INHERITED FROM: Oxocins || PP242 || yessotoxin |
| Ras GEF | 0.4466 | INHERITED FROM: Methapyrilene |
| Acetyl-CoA synthetase-like | 0.4466 | INHERITED FROM: Tetrachlorodibenzodioxin || GW 4064 || 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime |
| Toll/Interleukin receptor TIR domain | 0.5055 | INHERITED FROM: 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || Erlotinib Hydrochloride || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Quinolines || Piperazines || E804 bisindole || chrysin || Aripiprazole |
| Kringle-like | 0.5055 | INHERITED FROM: Benzoxazines || GSK1210151A || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Imidazolidines || Flavanones || Hydantoins || Y 27632 || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Flavonolignans || carbendazim || 3,3'-diindolylmethane || Benomyl || Atorvastatin || Chlorpromazine || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Chalcones || Silybin || Iridoids || Pyrrolidines || Acids, Heterocyclic || Oxazines || Benzophenanthridines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || kaempferol || baicalein || Phenytoin || genipin || 3-hydroxyflavone || Quinazolines || Dactinomycin || Porphyrins || chrysin || Nicotine || Apigenin || Pyridines || Solanaceous Alkaloids || Tetrapyrroles |
| HMG-box | 0.5181 | INHERITED FROM: Polyphenols |
| Voltage-gated potassium channels | 0.5195 | INHERITED FROM: Niflumic Acid || N-(1-(3-morpholin-4-ylphenyl)ethyl)-3-phenylacrylamide || N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)ac || Mibefradil || Tetrodotoxin || nefazodone || Astemizole || Flecainide |
| HSP20-like chaperones | 0.5216 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Adenosine Triphosphate |
| Myosin rod fragments | 0.5216 | INHERITED FROM: Nifedipine || Dihydropyridines |
| Class II aaRS and biotin synthetases | 0.5216 | INHERITED FROM: Cidofovir || Cytosine |
| TNF receptor-like | 0.5377 | INHERITED FROM: motexafin gadolinium || fludarabine || Demecolcine || Flavones || Fluorouracil || HhAntag691 || Isoindoles || Genistein || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Paraquat || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Pteridines || Vidarabine || Azepines || Polyphenols || Quinolones || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Quinolines || Imidazoles || Pyrrolidines || gemcitabine || Pentoxifylline || Benzophenanthridines || Celecoxib || Piperazines || Vemurafenib || Pyridinium Compounds || sanguinarine || osthol || Aripiprazole || Solanaceous Alkaloids || licochalcone A || Theobromine || Piperidines |
| Metalloproteases ("zincins"), catalytic domain | 0.539 | INHERITED FROM: Dioxanes || omapatrilat || Thiazepines || benazepril || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || Benomyl || Picolinic Acids || BQ 788 || 3-hydroxypicolinic acid || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || CGS 27023A || Thiepins || RTKI cpd || dieckol || Amitrole || Tetrazoles || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || varespladib methyl |
| Hemopexin-like domain | 0.553 | INHERITED FROM: piperine || Dioxanes || Benzylisoquinolines || Benzodioxoles || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Purine Nucleosides || Dioxolanes || pyrazolo(3,4-d)pyrimidine || Y 27632 || AICA ribonucleotide || Morpholines || salinomycin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavonolignans || deguelin || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || SB 203580 || Silybin || Berberine || Acids, Heterocyclic || Picolinic Acids || BQ 788 || Oxazines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || 3-hydroxypicolinic acid || Benzodiazepines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || CGS 27023A || Phenytoin || Quinazolines || Porphyrins || chrysin || 2-methyl-4-isothiazolin-3-one || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || dieckol || Tyrphostins || Ciprofloxacin || Amitrole || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || varespladib methyl || Tetrapyrroles || Aminoimidazole Carboxamide |
| Cystatin/monellin | 0.553 | INHERITED FROM: Lucanthone |
| Intermediate filament protein, coiled coil region | 0.5695 | INHERITED FROM: flavone |
| Immunoglobulin | 0.5836 | INHERITED FROM: 3,5-di-tert-butylchalcone 4'-carboxylic acid || Ketorolac || thieno(2,3-c)isoquinolin-5-one || HX 630 || orantinib || beta-Lactams || Lincosamides || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || ponatinib || Lenalidomide || (+)-JQ1 compound || Benzothiadiazines || gardiquimod || Triazoles || Cephalosporins || Aripiprazole |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.5994 | INHERITED FROM: pozanicline || Benzylisoquinolines || Dimethylphenylpiperazinium Iodide || Ro 15-4513 || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Muscimol || gabazine || Atracurium || L 663581 || Mivacurium || Bemegride || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || Diterpene Alkaloids || epibatidine || 1-(3-chlorophenyl)piperazine || Tubocurarine || bretazenil || Etomidate || loreclezole || tert-butylbicyclo-2-benzoate || Pentobarbital || Dihydro-beta-Erythroidine || Lobeline || 1-(2-methoxyphenyl)piperazine || 1-benzylpiperazine || Isoquinolines || Azabicyclo Compounds || Azocines || Pentylenetetrazole || Benzodiazepines || 1-(4-chlorophenyl)piperazine || Atropine || 1-(4-methoxyphenyl)piperazine || tert-butylbicyclophosphorothionate || Piperazines || cisatracurium || phenylpiperazine || fipronil || Nicotine || Bicuculline || 1-(3-trifluoromethylphenyl)piperazine || desformylflustrabromine || Zolpidem || Solanaceous Alkaloids || methyllycaconitine || Tropanes || CL 218872 || Quinolizines |
| Nicotinic receptor ligand binding domain-like | 0.5994 | INHERITED FROM: pozanicline || Benzylisoquinolines || Dimethylphenylpiperazinium Iodide || Ro 15-4513 || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Muscimol || gabazine || Atracurium || L 663581 || Mivacurium || Bemegride || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || Diterpene Alkaloids || epibatidine || 1-(3-chlorophenyl)piperazine || Tubocurarine || bretazenil || Etomidate || loreclezole || tert-butylbicyclo-2-benzoate || Pentobarbital || Dihydro-beta-Erythroidine || Lobeline || 1-(2-methoxyphenyl)piperazine || 1-benzylpiperazine || Isoquinolines || Azabicyclo Compounds || Azocines || Pentylenetetrazole || Benzodiazepines || 1-(4-chlorophenyl)piperazine || Atropine || 1-(4-methoxyphenyl)piperazine || tert-butylbicyclophosphorothionate || Piperazines || cisatracurium || phenylpiperazine || fipronil || Nicotine || Bicuculline || 1-(3-trifluoromethylphenyl)piperazine || desformylflustrabromine || Zolpidem || Solanaceous Alkaloids || methyllycaconitine || Tropanes || CL 218872 || Quinolizines |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.5994 | INHERITED FROM: Indoleacetic Acids || Fluoroquinolones || Moxifloxacin || Furocoumarins || lorcaserin || Pyrazolones || Benzoflavones || biochanin A || Umbelliferones || amentoflavone || bergamottin || 4-Hydroxycoumarins || Tetrachlorodibenzodioxin || 7,3'-dihydroxy-4'-methoxyisoflavone || Indoprofen || glabridin || Phenobarbital || Flavanones || ranirestat || Hydantoins || 2-Pyridinylmethylsulfinylbenzimidazoles || formononetin || Morphine Derivatives || beta-Naphthoflavone || Morphinans || Flavonolignans || Etodolac || Cyproheptadine || Cotinine || 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine || morin || Amobarbital || Oxazepam || Biflavonoids || muraglitazar || sitafloxacin || mangiferin || Chalcones || Scopoletin || Silybin || Opiate Alkaloids || 7-hydroxy-4-trifluoromethylcoumarin || Ezetimibe || Dioxins || 2',4'-dihydroxychalcone || MK-0524 || 2',5'-dihydroxychalcone || kaempferol || Azetines || auriculasin || Ofloxacin || Benzodiazepines || 3-hydroxydesloratadine || grepafloxacin || Phenytoin || naringenin chalcone || Phloretin || bropirimine || Benzodiazepinones || Loratadine || puerarin || Warfarin || chrysin || Phenylbutazone || Benzimidazoles || fisetin || Apigenin || naringenin || hydroxyphenytoin || Pyrrolizidine Alkaloids || Omeprazole || ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate || Morphine || galangin || licochalcone A || Equol || 7-hydroxy-4-(trifluoromethyl)coumarin || Hymecromone || daidzein || Kaempferols |
| Frizzled cysteine-rich domain | 0.6064 | INHERITED FROM: Carbamazepine || deguelin || 1-Methyl-3-isobutylxanthine || Panobinostat || Pyridines |
| PGBD-like | 0.6252 | INHERITED FROM: piperine || Dioxanes || Benzodioxoles || Thiadiazoles || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Xanthones || Dioxolanes || Hydantoins || Y 27632 || AICA ribonucleotide || Morpholines || salinomycin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavonolignans || deguelin || Quinoxalines || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || SB 203580 || Silybin || Deoxycytidine || Pyrrolidines || Acids, Heterocyclic || Picolinic Acids || BQ 788 || Oxazines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || 3-hydroxypicolinic acid || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || CGS 27023A || Phenytoin || Quinazolines || Aminopterin || Porphyrins || chrysin || 2-methyl-4-isothiazolin-3-one || Triazoles || Nicotine || RTKI cpd || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbazoles || dieckol || Tyrphostins || Ciprofloxacin || Amitrole || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Solanaceous Alkaloids || varespladib methyl || Piperidines || Tetrapyrroles || Aminoimidazole Carboxamide |
| MFS general substrate transporter | 0.6388 | INHERITED FROM: Cinchona Alkaloids || 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine || imidacloprid || Neonicotinoids || thiacloprid || pseudoisocyanine || repaglinide || Cimetidine || Heterocyclic Compounds, 3-Ring || N(1)-methylnicotinamide || 2-amino-3,4-dimethylimidazo(4,5-f)quinoline || Heterocyclic Compounds, 4 or More Rings || Uric Acid || Carbolines || Lactams || Cytochalasin B || acetamiprid || nitenpyram || Formyltetrahydrofolates || Atorvastatin || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Ceftibuten || Rifamycins || Imidazoles || Ethidium || Mirtazapine || trospium chloride || Cephalexin || Rifampin || Quinine || Phloretin || Serotonin || 6-carboxyfluorescein || Famotidine || Nortropanes || Flecainide || Ipratropium || Ranitidine || 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide || Belladonna Alkaloids || Thymidine || Lactams, Macrocyclic || Rosuvastatin Calcium || 7-(deoxyadenosin-N(6)-yl)aristolactam I || Quinidine |
| Cyclin-like | 0.6497 | INHERITED FROM: Citrinin || LG 100268 || Piroxicam || fludarabine || Atropine Derivatives || Lamivudine || Aminoacridines || MK-886 || labedipinedilol A || Fluorouracil || Phenanthridines || Oxazoles || Ro 41-5253 || Ritonavir || 7,3'-dihydroxy-4'-methoxyisoflavone || Heterocyclic Compounds, Bridged-Ring || Camptothecin || Flavanones || 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone || Ochratoxins || Benzothiazoles || pyrazolo(3,4-d)pyrimidine || 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-d || Zalcitabine || alvocidib || Guanine || Morpholines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || AC 93253 || N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea || Quinoxalines || Tocopherols || Acridines || CP-654577 || ON123300 || Silybin || Indazoles || ircinin-1 || Quinolines || Deoxycytidine || Acids, Heterocyclic || 6-(methylamino)pyrido(3,4-d)pyrimidine || Trabectedin || Letrozole || palbociclib || Oxazines || Zidovudine || Indolizines || Celecoxib || tylophorine || scriptaid || Bridged Bicyclo Compounds, Heterocyclic || Atropine || THRX 165724 || Thiazines || Nicotinic Acids || Piperazines || Quinazolines || abemaciclib || calyculin A || Dihydropyridines || goniothalamin || Benzimidazoles || Vemurafenib || Hypoxanthines || Nicotine || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Chromans || Thymidine || Thiazoles || Isonicotinic Acids || rottlerin || 1',2'-dihydrorotenone || Solanaceous Alkaloids || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || cryptolepine || Roscovitine |
| DEATH domain | 0.6578 | INHERITED FROM: EKB 569 || Imatinib Mesylate || fludarabine || Indoleacetic Acids || Benzoxazines || Flavones || abexinostat || brevetoxin 2 || Phthalimides || HhAntag691 || Isoindoles || Phenanthridines || Thioctic Acid || Umbelliferones || polyphenon E || rubimaillin || gardenin B || Cantharidin || Genistein || dracorhodin || Purine Nucleosides || Paraquat || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Pteridines || Flavanones || Fusaric Acid || quinoline-val-asp(OMe)-CH2-OPH || Benzothiazoles || Heterocyclic Compounds, 4 or More Rings || Vidarabine || alvocidib || Guanine || Azepines || SRT2183 || Terfenadine || Nigericin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || 5-methylselenylmethyl-2'-deoxyuridine || Oxocins || Polyphenols || Pyrazines || Calcimycin || MitoTEMPO || Pterins || indole-3-carbinol || Thiophenes || morin || Tocopherols || Adenosine || Riluzole || Quinolones || 5-phenylselenylmethyl-2'-deoxyuridine || Pyrones || idelalisib || ON123300 || Chalcones || 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid || Uridine || ircinin-1 || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Quinolines || Deoxycytidine || Imidazoles || Pyrrolidines || Acids, Heterocyclic || casticin || 4-methylene-2-octyl-5-oxofuran-3-carboxylic acid || lonafarnib || Picolinic Acids || esculetin || Isoquinolines || Bortezomib || Miransertib || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || Flavonoids || Pentoxifylline || Oxazines || Benzophenanthridines || Benzofurans || auriculasin || SM 164 || Indolizines || Celecoxib || tylophorine || nutlin 3 || KN 62 || Clonidine || 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide || Piperazines || Quinazolines || Benzodiazepinones || Dactinomycin || 9-methoxycamptothecin || Win 55212-2 || Porphyrins || goniothalamin || Cladribine || CFM 1 || Vemurafenib || Triazoles || Sorafenib || fisetin || Capsaicin || Staurosporine || STF 083010 || Apigenin || Pyridines || N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Carbazoles || norcantharidin || Allopurinol || Pyridinium Compounds || sanguinarine || echimidine || osthol || Quercetin || Bendamustine Hydrochloride || Solanaceous Alkaloids || beta-solamarine || Theobromine || Piperidines || Tetrapyrroles |
| F-box domain | 0.6601 | INHERITED FROM: Pyrroles |
| cAMP-binding domain-like | 0.6885 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide |
| Histone-fold | 0.6944 | INHERITED FROM: Demecolcine || Benzylisoquinolines || Furans || 2,3-bis(3'-hydroxybenzyl)butyrolactone || Xanthenes || OTX015 || Xanthones || Thioxanthenes || Heterocyclic Compounds, 4 or More Rings || Azepines || Coumestrol || Glutethimide || 4-Butyrolactone || Berberine || Isoquinolines || Folic Acid || Berberine Alkaloids || Triazoles || Lucanthone |
| gamma-Crystallin-like | 0.7049 | INHERITED FROM: tebuconazole |
| Terpenoid cyclases/Protein prenyltransferases | 0.7049 | INHERITED FROM: Olanzapine || Benzodiazepines |
| "Winged helix" DNA-binding domain | 0.7142 | INHERITED FROM: Harmala Alkaloids || Harmine |
| Serpins | 0.7147 | INHERITED FROM: Benzoflavones || Tetrachlorodibenzodioxin || Dioxins || Rifampin || periodate-oxidized adenosine || Polychlorinated Dibenzodioxins |
| Translation proteins SH3-like domain | 0.7265 | INHERITED FROM: Vitamin E |
| Snake toxin-like | 0.7284 | INHERITED FROM: rutecarpine |
| Globin-like | 0.7489 | INHERITED FROM: tebuconazole |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.7489 | INHERITED FROM: dinophysistoxin 1 |
| Class II aaRS ABD-related | 0.7489 | INHERITED FROM: Cidofovir |
| Glutathione synthetase ATP-binding domain-like | 0.7554 | INHERITED FROM: GW 4064 |
| Homeodomain-like | 0.7621 | INHERITED FROM: Chir 98014 || Panobinostat |
| SpoIIaa-like | 0.7926 | INHERITED FROM: Zidovudine || Thymidine |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.7926 | INHERITED FROM: Vitamin E |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.8161 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Troglitazone || Heterocyclic Compounds, 4 or More Rings || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || pyrithione zinc || Porphyrins || Benzimidazoles || Triazoles || Chromans || Quercetin || Thiazoles || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || usnic acid || Tetrapyrroles |
| Orange domain-like | 0.8161 | INHERITED FROM: baicalin || Thiadiazoles || Flavanones || baicalein || Heterocyclic Oxides || Cyclic S-Oxides || MRK 003 || Thiazoles |
| E2F-DP heterodimerization region | 0.8395 | INHERITED FROM: Ritonavir || Coumarins || Ochratoxins || Nicotine || Solanaceous Alkaloids |
| LDL receptor-like module | 0.8546 | INHERITED FROM: Olanzapine |
| EF-hand | 0.864 | INHERITED FROM: Imino Pyranoses || miglitol || Pyridines || Aminopyridines || 1-Deoxynojirimycin |
| KRAB domain (Kruppel-associated box) | 0.8775 | INHERITED FROM: GSK-J4 || Leflunomide || Benzazepines || Aflatoxin M1 || Isoxazoles |
| HLH, helix-loop-helix DNA-binding domain | 0.9115 | INHERITED FROM: Anthocyanins || baicalin || 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-y || Genistein || 2,3,7,8-tetrachlorodibenzofuran || Rifampin || propiconazole || Heterocyclic Oxides || Cyclic S-Oxides || Thiazoles || Indican || galangin || 2,3,4,7,8-pentachlorodibenzofuran |
| Polo-box domain | 0.915 | INHERITED FROM: Genistein || Troglitazone || Irinotecan |
| Enolase C-terminal domain-like | 0.941 | INHERITED FROM: Pteridines || Pterins || Aminopterin |
| Enolase N-terminal domain-like | 0.941 | INHERITED FROM: Pteridines || Pterins || Aminopterin |
| L domain-like | 0.9607 | INHERITED FROM: NVP-TAE684 || CMF regimen || Org 41841 || 6-(methylamino)pyrido(3,4-d)pyrimidine || Folfox protocol |
| Kazal-type serine protease inhibitors | 0.9643 | INHERITED FROM: naringin || trospium chloride || Nortropanes || Rosuvastatin Calcium |
| Trypsin-like serine proteases | 1 | INHERITED FROM: 4-Hydroxycoumarins || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || merbarone || Thiobarbiturates || Warfarin |
| Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: Panobinostat |
| Actin-like ATPase domain | 1 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || indirubin-3'-monoxime || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || pyrithione zinc || Hemin || Benzimidazoles || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) |
| C-type lectin-like | 1 | INHERITED FROM: Nebivolol |
| Spermadhesin, CUB domain | 1 | INHERITED FROM: Panobinostat |
| Cystine-knot cytokines | 1 | INHERITED FROM: Anthocyanins || Isoindoles || Ramipril || GSK1210151A || N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || cyanidin || delphinidin || Benzoxazoles || Heterocyclic Compounds, 4 or More Rings || fulvic acid || Oxocins || Risperidone || Calcimycin || Adenine Nucleotides || systhane || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || SB 203580 || Opiate Alkaloids || MOPP protocol || Isoquinolines || Valsartan || Quinazolines || Purine Nucleotides || Protoporphyrins || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbazoles |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: 6-O-monoacetylmorphine || Tacrine || Morphine Derivatives || Amaryllidaceae Alkaloids || RPR 121056 || Galantamine || Heroin || Physostigmine |
| Insulin-like | 1 | INHERITED FROM: Morpholines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Dihydropyridines || Benzimidazoles |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: Tiotropium Bromide || Dioxanes || oxotremorine M || brucine N-oxide || Pilocarpine || abanoquil || Lurasidone Hydrochloride || 7-hydroxymitragynine || Quinuclidinyl Benzilate || broxaterol || N-methylhistamine || 5-methylurapidil || 5-methylfurtrethonium || 1,3-dipropyl-8-cyclopentylxanthine || quercitrin || (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) || Org 41841 || Oxymetazoline || 4-diphenylacetoxy-1,1-dimethylpiperidinium || 7-methyl-6,7,8,9,14,15-hexahydro-5H-benz(d)indolo(2,3-g)azecine || Pipecuronium || xylometazoline || A 86929 || alfuzosin || Oxotremorine || Ketanserin || N-Methylscopolamine || Vortioxetine || proanthocyanidin || 7-fluoro-2-oxo-4-(2-(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)ethyl)-1,2-dihydroquinoline-1-aceta || Tropicamide || indole || Idazoxan || Muscarine || BMY 7378 || 5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide || CGP 20712A |
| TNF-like | 1 | INHERITED FROM: peroben || brevetoxin 2 || Phenanthridines || Quinolones || Atorvastatin || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Clozapine || Pyridones || Benzophenanthridines || Piperazines || Vemurafenib || sanguinarine || Aripiprazole || candesartan |
| 4-helical cytokines | 1 | INHERITED FROM: 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || Flavones || Hesperidin || 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || brevetoxin 2 || Phthalimides || Isoindoles || Benzodioxoles || Azathioprine || Ro 41-5253 || epinastine || resiquimod || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || beta-Lactams || tofacitinib || Naphthyridines || Histamine || Pteridines || StemRegenin 1 || Benzoxazoles || Terfenadine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Morphinans || Oxocins || Flavonolignans || Polyphenols || Calcimycin || Adenine Nucleotides || Patulin || SR 144528 || Quinoxalines || FEC protocol || Nitrofurans || SB 203580 || Opiate Alkaloids || Quinolines || Deoxycytidine || Clozapine || INCB018424 || Imidazoles || Pyrrolidines || Acids, Heterocyclic || gemcitabine || Ergolines || Isoquinolines || Azabicyclo Compounds || Oxazines || Cocaine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || kaempferol || Nevirapine || Phloretin || FK 706 || Clonidine || Nicotinic Acids || Piperazines || Apomorphine || Dactinomycin || Famotidine || E804 bisindole || Ergot Alkaloids || 6-formylindolo(3,2-b)carbazole || Benzimidazoles || fisetin || Ranitidine || 4-methylhistamine || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbazoles || Thymidine || Tyrphostins || Cytochalasins || Ciprofloxacin || Aripiprazole || Thiazoles || Isonicotinic Acids || Tetrazoles || hesperetin || Tropanes || Aporphines || Piperidines || Tetrapyrroles || Kaempferols |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| GLA-domain | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| FAH | 0 | Direct |
| HCP-like | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Trefoil | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| BolA-like | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| UBC-like | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| SIS domain | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| YjeF N-terminal domain-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| DUSP-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| GroES-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| HAD-like | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| FF domain | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| N-(deoxy)ribosyltransferase-like | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| DNase I-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Lipoxigenase | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| AXH domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PUG domain-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| AhpD-like | 0 | Direct |
| LanC-like | 0 | Direct |
| Sema domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Pseudouridine synthase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| SNARE-like | 0 | Direct |
| MIT domain | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| ISP domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Nop domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Metallothionein | 0 | Direct |
| PP2C-like | 0 | Direct |
| Stathmin | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| PEBP-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| DNA clamp | 0 | Direct |
| Release factor | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| SRF-like | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| ITPase-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| BRCT domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| AlbA-like | 0 | Direct |
| R3H domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| BSD domain-like | 0 | Direct |
| L30e-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| FnI-like domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| ACP-like | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| LysM domain | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Aldolase | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| BEACH domain | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Phenylalanine zipper | 0 | Direct |
| PUA domain-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Bet v1-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| GAF domain-like | 0 | Direct |
| PKD domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| KA1-like | 0 | Direct |
| FKBP-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| SCOP hierarchy in SUPERFAMILY | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| HIN-2000 domain-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| TGS-like | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PWI domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| ADC-like | 0 | Direct |
| Probable bacterial effector-binding domain | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| LEM domain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Caspase-like | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| SNF-like | 0 | Direct |
| GFP-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| RGC domain-like | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Hook domain | 0 | Direct |
| Pentein | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Pentapeptide repeat-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Cytokine | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Flavoproteins | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| GTPase activation domain, GAP | 0 | Direct |
| DLC | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| STAT | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Connexin43 | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| LigT-like | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Synuclein | 0 | Direct |
| eIF1-like | 0 | Direct |
| Uteroglobin-like | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| ACT-like | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| TIMP-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| HIT-like | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| PRTase-like | 0 | Direct |
| L27 domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Integrin domains | 0 | Direct |
| Annexin | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Mss4-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Triple coiled coil domain of C-type lectins | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Hermes dimerisation domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Notch domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| WWE domain | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| WW domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Plakin repeat | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| PapD-like | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Translational machinery components | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| VPS9 domain | 0 | Direct |
| PH domain-like | 0.00001007 | Direct |
| SH3-domain | 0.004463 | Inherited |
| Protein kinase-like (PK-like) | 0.005743 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.008148 | Inherited |
| FYVE/PHD zinc finger | 0.01199 | Inherited |
| EGF/Laminin | 0.01457 | Inherited |
| RNA-binding domain, RBD | 0.01726 | Inherited |
| SH2 domain | 0.02702 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.02882 | Inherited |
| Ubiquitin-like | 0.04324 | Inherited |
| ARM repeat | 0.05683 | Inherited |
| Cysteine proteinases | 0.06643 | Inherited |
| beta-beta-alpha zinc fingers | 0.07353 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.0975 | Inherited |
| Galactose-binding domain-like | 0.1013 | Inherited |
| Nucleic acid-binding proteins | 0.1048 | Inherited |
| E set domains | 0.1402 | Inherited |
| Growth factor receptor domain | 0.1928 | Inherited |
| FAD/NAD(P)-binding domain | 0.2005 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.204 | Inherited |
| (Trans)glycosidases | 0.2073 | Inherited |
| Mitochondrial carrier | 0.2143 | Inherited |
| SMAD/FHA domain | 0.2214 | Inherited |
| Leucine zipper domain | 0.2214 | Inherited |
| PX domain | 0.2288 | Inherited |
| Cadherin-like | 0.2428 | Inherited |
| Fibronectin type III | 0.2443 | Inherited |
| SET domain | 0.2701 | Inherited |
| Interleukin 8-like chemokines | 0.2879 | Inherited |
| p53-like transcription factors | 0.2973 | Inherited |
| PLP-dependent transferases | 0.3174 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.3296 | Inherited |
| Thioredoxin-like | 0.3481 | Inherited |
| Periplasmic binding protein-like I | 0.3481 | Inherited |
| DBL homology domain (DH-domain) | 0.3513 | Inherited |
| MHC antigen-recognition domain | 0.3595 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.3675 | Inherited |
| vWA-like | 0.3793 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3825 | Inherited |
| Fibrinogen C-terminal domain-like | 0.4206 | Inherited |
| Alkaline phosphatase-like | 0.4333 | Inherited |
| Ras GEF | 0.4466 | Inherited |
| Acetyl-CoA synthetase-like | 0.4466 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.5055 | Inherited |
| Kringle-like | 0.5055 | Inherited |
| HMG-box | 0.5181 | Inherited |
| Voltage-gated potassium channels | 0.5195 | Inherited |
| HSP20-like chaperones | 0.5216 | Inherited |
| Myosin rod fragments | 0.5216 | Inherited |
| Class II aaRS and biotin synthetases | 0.5216 | Inherited |
| TNF receptor-like | 0.5377 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.539 | Inherited |
| Hemopexin-like domain | 0.553 | Inherited |
| Cystatin/monellin | 0.553 | Inherited |
| Intermediate filament protein, coiled coil region | 0.5695 | Inherited |
| Immunoglobulin | 0.5836 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.5994 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5994 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.5994 | Inherited |
| Frizzled cysteine-rich domain | 0.6064 | Inherited |
| PGBD-like | 0.6252 | Inherited |
| MFS general substrate transporter | 0.6388 | Inherited |
| Cyclin-like | 0.6497 | Inherited |
| DEATH domain | 0.6578 | Inherited |
| F-box domain | 0.6601 | Inherited |
| cAMP-binding domain-like | 0.6885 | Inherited |
| Histone-fold | 0.6944 | Inherited |
| gamma-Crystallin-like | 0.7049 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 0.7049 | Inherited |
| "Winged helix" DNA-binding domain | 0.7142 | Inherited |
| Serpins | 0.7147 | Inherited |
| Translation proteins SH3-like domain | 0.7265 | Inherited |
| Snake toxin-like | 0.7284 | Inherited |
| Globin-like | 0.7489 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.7489 | Inherited |
| Class II aaRS ABD-related | 0.7489 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.7554 | Inherited |
| Homeodomain-like | 0.7621 | Inherited |
| SpoIIaa-like | 0.7926 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.7926 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.8161 | Inherited |
| Orange domain-like | 0.8161 | Inherited |
| E2F-DP heterodimerization region | 0.8395 | Inherited |
| LDL receptor-like module | 0.8546 | Inherited |
| EF-hand | 0.864 | Inherited |
| KRAB domain (Kruppel-associated box) | 0.8775 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.9115 | Inherited |
| Polo-box domain | 0.915 | Inherited |
| Enolase C-terminal domain-like | 0.941 | Inherited |
| Enolase N-terminal domain-like | 0.941 | Inherited |
| L domain-like | 0.9607 | Inherited |
| Kazal-type serine protease inhibitors | 0.9643 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| Concanavalin A-like lectins/glucanases | 1 | Inherited |
| Actin-like ATPase domain | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| Spermadhesin, CUB domain | 1 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| TNF-like | 1 | Inherited |
| 4-helical cytokines | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| beta-CASP RNA-metabolising hydrolases | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| AlkB-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Pentapeptide repeats | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
| BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Acetylcholinesterase-like | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Ornithine decarboxylase antizyme-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| Putative glucosidase YicI, domain 3 | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Alkaline phosphatase | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0 | DIRECT |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| A20-like zinc finger | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| Lysophospholipase | 0 | DIRECT |
| Plakophilin 1 helical region | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Ribosomal protein L3 | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| FKBP immunophilin/proline isomerase | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Penta-EF-hand proteins | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Tetratricopeptide repeat (TPR) | 0 | DIRECT |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | DIRECT |
| Synatpobrevin N-terminal domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Renal dipeptidase | 0 | DIRECT |
| Phosducin | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| PWWP domain | 0 | DIRECT |
| Bacterial PLC | 0 | DIRECT |
| SMAD4-binding domain of oncoprotein Ski | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Uteroglobin-like | 0 | DIRECT |
| Complement components | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| Fibroblast growth factors (FGF) | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| DIX domain | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| DEATH effector domain, DED | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Hermes transposase-like | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| T-box | 0 | DIRECT |
| TK-like Pyr module | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| GAF domain | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Cytidylytransferase | 0 | DIRECT |
| Lipoxigenase N-terminal domain | 0 | DIRECT |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Prokaryotic proteases | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Nuclear receptor | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| TatD Mg-dependent DNase-like | 0 | DIRECT |
| FucT-like | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| MIF-related | 0 | DIRECT |
| Platelet-derived growth factor-like | 0 | DIRECT |
| Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Selenoprotein W-related | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| PUG domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Dachshund-homology domain | 0 | DIRECT |
| PHD domain | 0 | DIRECT |
| FolH catalytic domain-like | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| SelR domain | 0 | DIRECT |
| Interferon regulatory factor | 0 | DIRECT |
| Adapter protein APS, dimerisation domain | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Flavin-binding PAS domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Ribosomal proteins L24p and L21e | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Crisp domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Pointed domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Starch-binding domain | 0 | DIRECT |
| Transglutaminase N-terminal domain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| Leukotriene A4 hydrolase C-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| SPOC domain | 0 | DIRECT |
| p53 DNA-binding domain-like | 0 | DIRECT |
| Synapsin domain | 0 | DIRECT |
| Glycosyl hydrolases family 35 catalytic domain | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Clathrin heavy-chain linker domain | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Cysteine rich domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| IMD domain | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Thioltransferase | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| Sedlin (SEDL) | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Short-chain cytokines | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| HIN-200/IF120x domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Centromere-binding | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Osteonectin | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| Lectin leg-like | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| GS domain | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Triple coiled coil domain of C-type lectins | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | DIRECT |
| VWC domain | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| HtrA-like serine proteases | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| RUN domain | 0 | DIRECT |
| HkH motif-containing C2H2 finger | 0 | DIRECT |
| Diacylglycerol kinase-like | 0 | DIRECT |
| GAT domain | 0 | DIRECT |
| Aldo-keto reductases (NADP) | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
| CPH domain | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| PIWI domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Nuclear movement domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| YicI N-terminal domain-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Retinoblastoma tumor suppressor domains | 0 | DIRECT |
| ProC C-terminal domain-like | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| YjeF N-terminal domain-like | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| GDI-like N domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Kringle modules | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| MYND zinc finger | 0 | DIRECT |
| Animal lipoxigenases | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| GABARAP-like | 0 | DIRECT |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Oligosaccharide phosphorylase | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Arylamine N-methyltransferase | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| ECR1 N-terminal domain-like | 0 | DIRECT |
| Bee venom hyaluronidase | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| Synapsin C-terminal domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| C2 set domains | 0 | DIRECT |
| Link domain | 0 | DIRECT |
| Aminomethyltransferase folate-binding domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Pseudouridine synthase II TruB | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Family 1 of glycosyl hydrolase | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| PNP-oxidase like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| FAH | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| PCI domain (PINT motif) | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| Variant SAM domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Transglutaminase core | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| Caspase recruitment domain, CARD | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| 5' nucleotidase-like | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | DIRECT |
| Integrin beta EGF-like domains | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Extended AAA-ATPase domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| gamma-adaptin C-terminal appendage domain-like | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| Exostosin | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Interleukin-1 (IL-1) | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| THAP domain | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | DIRECT |
| STAT DNA-binding domain | 0 | DIRECT |
| Cytochrome p450 reductase N-terminal domain-like | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Tyrosine-dependent oxidoreductases | 0 | DIRECT |
| Cripto EGF-like domain-like | 0 | DIRECT |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| MBT repeat | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| RGC domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Pyridoxal-dependent decarboxylase | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| TK-like PP module | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Carbamilase | 0 | DIRECT |
| STAR domain | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Ecto-ART | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0.001134 | INHERITED FROM: GSK2141795 || GSK2110183 || aflatoxin B2 || Guanosine Triphosphate || Indoles || Catechin |
| SH3-domain | 0.003867 | INHERITED FROM: aflatoxin B2 || ponatinib || Azoles |
| Canonical RBD | 0.004846 | INHERITED FROM: pateamine A || Pyrazoles || Vinca Alkaloids || Oxocins || ((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one) || PP242 || ICG 001 || yessotoxin |
| Protein kinases, catalytic subunit | 0.007254 | INHERITED FROM: Citrinin || Imatinib Mesylate || SU 5402 || PI 620 || Flavones || NVP-TAE684 || labedipinedilol A || bisindolylmaleimide || staurosporine aglycone || BMS 754807 || Isoindoles || Benzodioxoles || PD 173074 || WY-135 || Cyclic GMP || ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate || Pyridazines || orantinib || indole-5-carboxamide || Cantharidin || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || baohuoside I || baricitinib || Semaxinib || GSK2141795 || 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbo || AG-012986 || Heterocyclic Compounds, 3-Ring || Naphthyridines || Phenazines || dracorhodin || Camptothecin || SU 6656 || aucubin || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Dasatinib || 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine || Dioxolanes || Coumarins || Niacinamide || Ochratoxins || GSK2110183 || 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine || 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione || Benzothiazoles || rutacarpine || Pyrans || fumosorinone || tanespimycin || Y 27632 || aflatoxin B2 || alvocidib || 5-iodo-3-(2-azetidinylmethoxy)pyridine || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Lactams || Polyphenols || Pyrazines || 5-iodotubercidin || ponatinib || bisindolylmaleimide I || WHI P154 || deguelin || Quinoxalines || Formyltetrahydrofolates || ML 9 || GSK 1363089 || Alkaloids || dehydroglyasperin C || dictamnine || Azoles || 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone || ON123300 || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || Quinolines || N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3- || Imidazoles || 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine || 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone || 103D5R || Pyridones || Acids, Heterocyclic || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide || pifithrin || 6-(methylamino)pyrido(3,4-d)pyrimidine || Indoles || Isoquinolines || AG 1879 || Pyrroles || Adenosine Diphosphate || 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione || Dioxoles || Oxazines || A 419259 || Benzopyrans || Tubercidin || quercetin 4'-O-glucopyranoside || ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate || APS-2-79 || Nicotinic Acids || Piperazines || Quinazolines || Pyocyanine || Folfox protocol || 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol || Win 55212-2 || Maleimides || napabucasin || Benzimidazoles || NVP-AEW541 || Sorafenib || Iridoid Glycosides || Staurosporine || Pyridines || 6,7-dimethoxy-3-phenylquinoxaline || Aminopyridines || Carbazoles || norcantharidin || trametinib || Rimonabant || Thiazoles || rottlerin || didymin || Lactams, Macrocyclic || 1',2'-dihydrorotenone || Maytansine || Solanaceous Alkaloids || coptisine || 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy || fascaplysine || Piperidines || Sunitinib |
| SH2 domain | 0.02289 | INHERITED FROM: Imatinib Mesylate || N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || stattic || Methylthiouracil || 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester || Pyridazines || baricitinib || tofacitinib || 4'-methoxy licoflavanone || Dasatinib || Niacinamide || Azepines || Polyphenols || WP1066 || ponatinib || Azoles || 4-acetylantroquinonol B || N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidine || INCB018424 || alpinumisoflavone || Imidazoles || (+)-JQ1 compound || AG 1879 || isoquercitrin || Triazoles || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || AZD 1480 || norcantharidin |
| Growth factor receptor domain | 0.1364 | INHERITED FROM: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine || NVP-TAE684 || Tetrachlorodibenzodioxin || Heterocyclic Compounds, 3-Ring || Lactams || CMF regimen || ponatinib || Adenine Nucleotides || Formyltetrahydrofolates || Penicillin G || Dioxins || Tetrahydrofolates || 6-(methylamino)pyrido(3,4-d)pyrimidine || Dioxoles || Quinazolines || Folfox protocol || Vemurafenib || Pyridines || Thiazoles |
| ABC transporter ATPase domain-like | 0.1512 | INHERITED FROM: fexofenadine || Fluoresceins || oltipraz || calcein AM || Furocoumarins || Pyrazolones || Penicillins || 8-azidoadenosine 5'-triphosphate || fluorexon || Thioguanine || Xanthenes || N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Vinca Alkaloids || Secologanin Tryptamine Alkaloids || senecionine || Ticlopidine || macitentan || Adenosine Triphosphate || Heterocyclic Compounds, 4 or More Rings || 2-Pyridinylmethylsulfinylbenzimidazoles || formononetin || Terfenadine || AC 93253 || Lactams || Bosentan || Pyrazines || Cyproheptadine || Tolvaptan || Mefloquine || Rifamycins || Phenothiazines || Quinolines || Acids, Heterocyclic || Rifampin || bisbenzimide ethoxide trihydrochloride || 6-bromoindirubin-3'-oxime || Benzofurans || Saquinavir || Zidovudine || Celecoxib || 3',4',7-trihydroxyisoflavone || Nelfinavir || Nicotinic Acids || Piperazines || Loratadine || Dihydropyridines || Maleimides || cerivastatin || chrysin || Ergot Alkaloids || Phenylbutazone || Clotrimazole || Benzimidazoles || Thienopyridines || TAK-875 || Benzbromarone || Thymidine || verlukast || pitavastatin || Thiazoles || Tetrazoles || hesperetin || Lactams, Macrocyclic || Sulfinpyrazone || Methoxsalen || Rosuvastatin Calcium |
| Classic zinc finger, C2H2 | 0.1787 | INHERITED FROM: GSK-J4 || Leflunomide || Benzazepines || pomalidomide || Aflatoxin M1 || Isoxazoles |
| Mitochondrial carrier | 0.1995 | INHERITED FROM: Adenosine Triphosphate || Tunicamycin || Atrazine || Triazines || Thymidine |
| Leucine zipper domain | 0.1995 | INHERITED FROM: Citrinin || piperine || Phenanthrolines || 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)am || Penicillins || Phthalimides || Isoindoles || Benzodioxoles || cylindrospermopsin || Oxazoles || dinophysistoxin 1 || Tetrachlorodibenzodioxin || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Heterocyclic Compounds, 3-Ring || quinomethionate || Vinca Alkaloids || Pteridines || Leflunomide || Ochratoxins || Heterocyclic Compounds, 4 or More Rings || Uric Acid || Azepines || Carbamazepine || Pyrazines || NSC668394 || SR 144528 || Quinoxalines || Nifedipine || sauchinone || Penicillin G || SB 203580 || Azoles || Cyclic AMP || Quinolines || Dioxins || BIX 02189 || Pyrrolidines || Acids, Heterocyclic || Pyrimidine Nucleosides || Indoles || Isoquinolines || Flavonoids || Dioxoles || nefazodone || Oxazines || Anisomycin || Cocaine || Benzofurans || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Hemin || Piperazines || CP 31398 || 9-methoxycamptothecin || Aminopterin || 4-Quinolones || Indole Alkaloids || O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate || fisetin || Pyridines || Isoxazoles || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Rimonabant || Quercetin || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || Tetrazoles || rottlerin || Pyrazinamide || Piperidines || Tetrapyrroles |
| Ubiquitin-related | 0.2064 | INHERITED FROM: dinophysistoxin 1 |
| Fibronectin type III | 0.2205 | INHERITED FROM: dorsomorphin || aflatoxin B2 || ponatinib || Dioxoles || Panobinostat || Cytidine || Pyridines || Aminopyridines |
| PX domain | 0.2288 | INHERITED FROM: Go 6976 |
| Cadherin | 0.2353 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
| LIM domain | 0.2453 | INHERITED FROM: Pyrimidines || Aflatoxin B1 |
| Interleukin 8-like chemokines | 0.2623 | INHERITED FROM: Imatinib Mesylate || Propidium || fexofenadine || Demecolcine || Flavones || Hesperidin || 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || palmatine || Phenanthridines || 1-carboxyheptylimidazole || pevonedistat || Ritonavir || 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || tofacitinib || Oxypurinol || Itraconazole || PD168393 || Vinca Alkaloids || Troglitazone || Dasatinib || Pteridines || Benzoxazoles || Terfenadine || Morphine Derivatives || Oxazolone || Morphinans || Polyphenols || BIRB 796 || Calcimycin || Pterins || roflumilast N-oxide || Emetine || Quinolones || SB 203580 || Opiate Alkaloids || Quinolines || Imidazoles || Roflumilast || Pyrrolidines || gemcitabine || Albendazole || Quinolinium Compounds || Azabicyclo Compounds || Cocaine || 3'-methoxy-4'-nitroflavone || Dequalinium || captax || coralyne || Telmisartan || Rutin || Puromycin || Piperazines || Aminopterin || E804 bisindole || luliconazole || 2-methyl-4-isothiazolin-3-one || 6-formylindolo(3,2-b)carbazole || Benzimidazoles || amorolfine || Lopinavir || Allopurinol || Colchicine || Aripiprazole || Thiazoles || Tropanes || Piperidines |
| Dual specificity phosphatase-like | 0.2623 | INHERITED FROM: cylindrospermopsin || Leflunomide || Isoxazoles |
| PLC-like (P variant) | 0.271 | INHERITED FROM: aflatoxin B2 || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 |
| G proteins | 0.2812 | INHERITED FROM: Zoledronic Acid || Guanine Nucleotides || Risedronic Acid || Guanosine Triphosphate |
| DBL homology domain (DH-domain) | 0.3225 | INHERITED FROM: aflatoxin B2 || Aminopyridines |
| MHC antigen-recognition domain | 0.3304 | INHERITED FROM: valdecoxib || Ketorolac || beta-Lactams || Lincosamides || Chlorothiazide || Lactams || entinostat || Penicillin G || Quinolines || Ampicillin || Diltiazem || Gefitinib || Benzothiadiazines || Thiazines || Quinazolines || Heterocyclic Oxides || Cyclic S-Oxides || MRK 003 || Omeprazole || Cephalosporins |
| Fibrinogen C-terminal domain-like | 0.3898 | INHERITED FROM: Adenosine Diphosphate |
| cAMP-binding domain | 0.4029 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Purine Nucleotides |
| Ras-binding domain, RBD | 0.4029 | INHERITED FROM: ZSTK474 || Benzothiazoles || Indazoles || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin |
| I set domains | 0.4063 | INHERITED FROM: PD 173074 || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || aflatoxin B2 || ponatinib || Lenalidomide |
| Acetyl-CoA synthetase-like | 0.4159 | INHERITED FROM: Tetrachlorodibenzodioxin || GW 4064 || 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime |
| Cyclin | 0.4295 | INHERITED FROM: Citrinin || LG 100268 || Piroxicam || fludarabine || Atropine Derivatives || Lamivudine || Aminoacridines || labedipinedilol A || Fluorouracil || Phenanthridines || Ritonavir || 7,3'-dihydroxy-4'-methoxyisoflavone || Heterocyclic Compounds, Bridged-Ring || Flavanones || 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone || Ochratoxins || Benzothiazoles || pyrazolo(3,4-d)pyrimidine || Zalcitabine || alvocidib || Guanine || Morpholines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || AC 93253 || N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea || Acridines || CP-654577 || Chalcones || Silybin || Indazoles || Phenothiazines || Deoxycytidine || Ethidium || Acids, Heterocyclic || Trabectedin || Isoquinolines || palbociclib || Oxazines || Zidovudine || Pyrimidinones || Indolizines || tylophorine || scriptaid || Bridged Bicyclo Compounds, Heterocyclic || Folic Acid || Thiazines || Nicotinic Acids || Piperazines || Quinazolines || abemaciclib || goniothalamin || Vemurafenib || Hypoxanthines || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Belladonna Alkaloids || Chromans || Thymidine || Thiazoles || Isonicotinic Acids || 1',2'-dihydrorotenone || Solanaceous Alkaloids || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || cryptolepine || usnic acid || Isoniazid |
| FHA domain | 0.4295 | INHERITED FROM: fludarabine || Dioxolanes || Vidarabine || myristicin |
| Ras GEF | 0.4431 | INHERITED FROM: Methapyrilene |
| Motor proteins | 0.4452 | INHERITED FROM: Xanthenes || Xanthones || Thioxanthenes || palbociclib || Folic Acid || Lucanthone |
| HMG-box | 0.4856 | INHERITED FROM: Polyphenols |
| Toll/Interleukin receptor TIR domain | 0.5053 | INHERITED FROM: 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || Erlotinib Hydrochloride || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Bortezomib || E804 bisindole || chrysin || Aripiprazole |
| Hemopexin-like domain | 0.5205 | INHERITED FROM: piperine || Dioxanes || Benzylisoquinolines || Benzodioxoles || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Purine Nucleosides || Dioxolanes || pyrazolo(3,4-d)pyrimidine || Y 27632 || AICA ribonucleotide || Morpholines || salinomycin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavonolignans || deguelin || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || SB 203580 || Silybin || Berberine || Acids, Heterocyclic || Picolinic Acids || BQ 788 || Oxazines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || 3-hydroxypicolinic acid || Benzodiazepines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || CGS 27023A || Phenytoin || Porphyrins || chrysin || 2-methyl-4-isothiazolin-3-one || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || dieckol || Tyrphostins || Ciprofloxacin || Amitrole || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || varespladib methyl || Tetrapyrroles || Aminoimidazole Carboxamide |
| Matrix metalloproteases, catalytic domain | 0.5205 | INHERITED FROM: piperine || Dioxanes || Benzodioxoles || Thiadiazoles || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Xanthones || Purine Nucleosides || Dioxolanes || Y 27632 || AICA ribonucleotide || Morpholines || salinomycin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavonolignans || deguelin || Quinoxalines || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || SB 203580 || Silybin || Acids, Heterocyclic || Picolinic Acids || BQ 788 || Oxazines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || 3-hydroxypicolinic acid || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || CGS 27023A || Phenytoin || Quinazolines || Aminopterin || Porphyrins || chrysin || 2-methyl-4-isothiazolin-3-one || Nicotine || RTKI cpd || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || dieckol || Tyrphostins || Ciprofloxacin || Amitrole || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Solanaceous Alkaloids || varespladib methyl || Piperidines || Tetrapyrroles || Aminoimidazole Carboxamide |
| Intermediate filament protein, coiled coil region | 0.5361 | INHERITED FROM: flavone |
| Myosin rod fragments | 0.5371 | INHERITED FROM: Nifedipine || Dihydropyridines |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.5371 | INHERITED FROM: Tunicamycin || Cidofovir || Cytosine |
| Integrin A (or I) domain | 0.5537 | INHERITED FROM: GSK1210151A || Hydantoins || Calcimycin || Atorvastatin || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Phenytoin || Thiazoles |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.5659 | INHERITED FROM: pozanicline || Benzylisoquinolines || Dimethylphenylpiperazinium Iodide || Ro 15-4513 || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Muscimol || gabazine || Atracurium || L 663581 || Mivacurium || Bemegride || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || Diterpene Alkaloids || epibatidine || 1-(3-chlorophenyl)piperazine || Tubocurarine || bretazenil || Etomidate || loreclezole || tert-butylbicyclo-2-benzoate || Pentobarbital || Dihydro-beta-Erythroidine || Lobeline || 1-(2-methoxyphenyl)piperazine || 1-benzylpiperazine || Isoquinolines || Azabicyclo Compounds || Azocines || Pentylenetetrazole || Benzodiazepines || 1-(4-chlorophenyl)piperazine || 1-(4-methoxyphenyl)piperazine || tert-butylbicyclophosphorothionate || Piperazines || cisatracurium || phenylpiperazine || fipronil || Nicotine || Bicuculline || 1-(3-trifluoromethylphenyl)piperazine || desformylflustrabromine || Zolpidem || Solanaceous Alkaloids || methyllycaconitine || Tropanes || CL 218872 || Quinolizines |
| Laminin-type module | 0.5731 | INHERITED FROM: Zoledronic Acid || palbociclib |
| Frizzled cysteine-rich domain | 0.5731 | INHERITED FROM: Carbamazepine || deguelin || 1-Methyl-3-isobutylxanthine || Panobinostat || Pyridines |
| UDPGT-like | 0.5731 | INHERITED FROM: Bile Pigments || Indoleacetic Acids || Fluoroquinolones || Moxifloxacin || Furocoumarins || lorcaserin || Pyrazolones || Benzoflavones || biochanin A || Isoindoles || cylindrospermopsin || Umbelliferones || amentoflavone || Oxazoles || bergamottin || 4-Hydroxycoumarins || Tetrachlorodibenzodioxin || 7,3'-dihydroxy-4'-methoxyisoflavone || Heterocyclic Compounds, 3-Ring || Imidazolidines || Indoprofen || glabridin || Phenobarbital || Flavanones || ranirestat || Coumarins || Hydantoins || Pyrrolidinones || Heterocyclic Compounds, 4 or More Rings || 2-Pyridinylmethylsulfinylbenzimidazoles || formononetin || Morphine Derivatives || beta-Naphthoflavone || Morphinans || Flavonolignans || Pyrazines || Etodolac || Cyproheptadine || Cotinine || 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine || morin || Amobarbital || Oxazepam || Biflavonoids || muraglitazar || sitafloxacin || mangiferin || Chalcones || Scopoletin || Silybin || Opiate Alkaloids || 7-hydroxy-4-trifluoromethylcoumarin || Ezetimibe || Indomethacin || Imidazoles || Dioxins || Acids, Heterocyclic || 2',4'-dihydroxychalcone || MK-0524 || 2',5'-dihydroxychalcone || Rifampin || kaempferol || Azetines || auriculasin || Ofloxacin || Benzodiazepines || 3-hydroxydesloratadine || grepafloxacin || Phenytoin || naringenin chalcone || Phloretin || bropirimine || Benzodiazepinones || Loratadine || puerarin || Warfarin || Irinotecan || chrysin || Phenylbutazone || Benzimidazoles || Triazoles || fisetin || Barbiturates || Apigenin || naringenin || hydroxyphenytoin || Pyrrolizidine Alkaloids || Omeprazole || ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate || Morphine || galangin || Solanaceous Alkaloids || licochalcone A || Equol || 7-hydroxy-4-(trifluoromethyl)coumarin || Hymecromone || daidzein || Polychlorinated Dibenzodioxins || Kaempferols |
| Nicotinic receptor ligand binding domain-like | 0.5783 | INHERITED FROM: pozanicline || Benzylisoquinolines || Dimethylphenylpiperazinium Iodide || Ro 15-4513 || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Muscimol || gabazine || Atracurium || L 663581 || Mivacurium || Bemegride || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || Diterpene Alkaloids || epibatidine || 1-(3-chlorophenyl)piperazine || Tubocurarine || bretazenil || Etomidate || loreclezole || tert-butylbicyclo-2-benzoate || Pentobarbital || Dihydro-beta-Erythroidine || Lobeline || 1-(2-methoxyphenyl)piperazine || 1-benzylpiperazine || Isoquinolines || Azabicyclo Compounds || Azocines || Pentylenetetrazole || Benzodiazepines || 1-(4-chlorophenyl)piperazine || 1-(4-methoxyphenyl)piperazine || tert-butylbicyclophosphorothionate || Piperazines || cisatracurium || phenylpiperazine || fipronil || Nicotine || Bicuculline || 1-(3-trifluoromethylphenyl)piperazine || desformylflustrabromine || Zolpidem || Solanaceous Alkaloids || methyllycaconitine || Tropanes || CL 218872 || Quinolizines |
| MMP N-terminal domain | 0.5921 | INHERITED FROM: piperine || Dioxanes || Benzodioxoles || Thiadiazoles || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Xanthones || Dioxolanes || Hydantoins || Y 27632 || AICA ribonucleotide || Morpholines || salinomycin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Flavonolignans || deguelin || Quinoxalines || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || SB 203580 || Silybin || Deoxycytidine || Pyrrolidines || Acids, Heterocyclic || Picolinic Acids || BQ 788 || Oxazines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || 3-hydroxypicolinic acid || manganese(III)-tetrakis(4-benzoic acid)porphyrin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || CGS 27023A || Phenytoin || Quinazolines || Aminopterin || Porphyrins || chrysin || 2-methyl-4-isothiazolin-3-one || Triazoles || Nicotine || RTKI cpd || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Carbazoles || dieckol || Tyrphostins || Ciprofloxacin || Amitrole || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Solanaceous Alkaloids || varespladib methyl || Piperidines || Tetrapyrroles || Aminoimidazole Carboxamide |
| Proteasome subunits | 0.5921 | INHERITED FROM: stattic || Pyridazines || EGFR tyrosine kinase inhibitor 324674 || quercitrin || Hydralazine || Phthalazines || Heterocyclic Oxides || Cyclic S-Oxides |
| Glutathione peroxidase-like | 0.612 | INHERITED FROM: Thioctic Acid || Paraquat || Flavanones || Pyrimidine Nucleosides || naringenin || Pyridinium Compounds || Quercetin || Tetrapyrroles |
| S100 proteins | 0.6318 | INHERITED FROM: Tetrachlorodibenzodioxin || Heterocyclic Compounds, 3-Ring || Azacitidine || Imino Pyranoses || Dioxins || miglitol || Cytidine || Decitabine || 1-Deoxynojirimycin || Piperidines |
| Arylsulfatase | 0.6318 | INHERITED FROM: Oxocins || PP242 || yessotoxin |
| GABA-aminotransferase-like | 0.6512 | INHERITED FROM: Tetrachlorodibenzodioxin || Heterocyclic Compounds, 3-Ring || Dioxins |
| F-box domain | 0.6582 | INHERITED FROM: Pyrroles |
| Crystallins/Ca-binding development proteins | 0.6725 | INHERITED FROM: tebuconazole |
| C1 set domains (antibody constant domain-like) | 0.6826 | INHERITED FROM: valdecoxib || Fluoroquinolones || Ketorolac || beta-Lactams || Lincosamides || Chlorothiazide || Lactams || entinostat || Penicillin G || Ampicillin || Diltiazem || Gefitinib || Benzothiadiazines || Thiazines || Quinazolines || Heterocyclic Oxides || Cyclic S-Oxides || MRK 003 || Omeprazole || Cephalosporins |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.6952 | INHERITED FROM: piperine || pyrrolidine dithiocarbamic acid || Isoindoles || Benzodioxoles || tofacitinib || scoparone || Resveratrol || Benzoxazoles || Carbolines || Polyphenols || Calcimycin || bisindolylmaleimide I || Harmala Alkaloids || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || INCB018424 || gemcitabine || Maleimides || fisetin || Decitabine || Piperidines |
| Serpins | 0.6967 | INHERITED FROM: Benzoflavones || Tetrachlorodibenzodioxin || Dioxins || Rifampin || periodate-oxidized adenosine || Polychlorinated Dibenzodioxins |
| Nucleosome core histones | 0.6969 | INHERITED FROM: Demecolcine || Benzylisoquinolines || Furans || 2,3-bis(3'-hydroxybenzyl)butyrolactone || Xanthenes || OTX015 || Xanthones || Thioxanthenes || Coumarins || Heterocyclic Compounds, 4 or More Rings || Azepines || Coumestrol || Alkaloids || Glutethimide || 4-Butyrolactone || Berberine || (+)-JQ1 compound || Isoquinolines || Folic Acid || Berberine Alkaloids || Grape Seed Proanthocyanidins || Triazoles || Lucanthone || Colchicine || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin |
| PDI-like | 0.7181 | INHERITED FROM: Tunicamycin |
| Globins | 0.7181 | INHERITED FROM: tebuconazole |
| Long-chain cytokines | 0.7181 | INHERITED FROM: 6,2',4'-trimethoxyflavone || 7-bromoindirubin-3'-oxime || Isoindoles || Azathioprine || Thalidomide || Adenine Nucleotides || Thiophenes || Quinoxalines || SB 203580 || Clozapine || Imidazoles || Acids, Heterocyclic || gemcitabine || Isoquinolines || Cocaine || Piperazines || Purine Nucleotides || Apomorphine || E804 bisindole || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || Niacin || Benzimidazoles || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Aripiprazole || Thiazoles || Tetrazoles || Aporphines || Piperidines |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.7181 | INHERITED FROM: Benzoflavones || Thioctic Acid || Purine Nucleosides || senkirkine || Phenothiazines || Pyrrolizidine Alkaloids |
| Fibronectin type II module | 0.7411 | INHERITED FROM: Phenanthridines || Flavanones || Y 27632 || salinomycin || Quinoxalines || Benzophenanthridines || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || baicalein || Porphyrins || chrysin || Apigenin || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tyrphostins || Tetrapyrroles |
| RING finger domain, C3HC4 | 0.7431 | INHERITED FROM: K 7174 |
| Amylase, catalytic domain | 0.7653 | INHERITED FROM: Phenobarbital || Barbiturates |
| Cell cycle transcription factor e2f-dp | 0.7653 | INHERITED FROM: Furans || Fluorouracil || Azathioprine || Ritonavir || Coumarins || Ochratoxins || Resveratrol || Carbolines || Harmala Alkaloids || Mercaptopurine || Harmine || Nicotine || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Solanaceous Alkaloids |
| Hairy Orange domain | 0.7886 | INHERITED FROM: baicalin || Thiadiazoles || Flavanones || baicalein || Heterocyclic Oxides || Cyclic S-Oxides || MRK 003 || Thiazoles |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.7886 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Troglitazone || Heterocyclic Compounds, 4 or More Rings || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || pyrithione zinc || Porphyrins || Benzimidazoles || Triazoles || Chromans || Quercetin || Thiazoles || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || usnic acid || Tetrapyrroles |
| Anticodon-binding domain of Class II aaRS | 0.7886 | INHERITED FROM: Cidofovir || Cytosine |
| ets domain | 0.7939 | INHERITED FROM: Triazoles |
| Voltage-gated potassium channels | 0.7968 | INHERITED FROM: Cinchona Alkaloids || Niflumic Acid || N-(1-(3-morpholin-4-ylphenyl)ethyl)-3-phenylacrylamide || Astemizole || Quinidine |
| LDL receptor-like module | 0.8296 | INHERITED FROM: Olanzapine |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0.8403 | INHERITED FROM: Vitamin E |
| Ngr ectodomain-like | 0.8585 | INHERITED FROM: Org 41841 |
| L domain | 0.8671 | INHERITED FROM: Flavones || NVP-TAE684 || Fluorouracil || Uracil || Pteridines || Resveratrol || Morpholines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || CMF regimen || Polyphenols || Quinoxalines || Formyltetrahydrofolates || Indazoles || Imidazoles || Pyridones || Tetrahydrofolates || 6-(methylamino)pyrido(3,4-d)pyrimidine || Oxazines || Rosiglitazone || Quinazolines || Folfox protocol || Aminoquinolines || Lapatinib || Cycloheximide || Tyrphostins || Piperidines |
| Glycerol-3-phosphate transporter | 0.8671 | INHERITED FROM: Zidovudine || Thymidine |
| KRAB domain (Kruppel-associated box) | 0.8792 | INHERITED FROM: GSK-J4 || Leflunomide || Benzazepines || Aflatoxin M1 || Isoxazoles |
| HLH, helix-loop-helix DNA-binding domain | 0.8906 | INHERITED FROM: Anthocyanins || baicalin || 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-y || 2,3,7,8-tetrachlorodibenzofuran || Rifampin || propiconazole || Heterocyclic Oxides || Cyclic S-Oxides || Thiazoles || Indican || galangin || 2,3,4,7,8-pentachlorodibenzofuran |
| TRASH domain | 0.8947 | INHERITED FROM: Aflatoxin M1 |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0.8947 | INHERITED FROM: dinophysistoxin 1 |
| Transforming growth factor (TGF)-beta | 0.9099 | INHERITED FROM: brevetoxin 2 || fulvic acid || Oxocins || Calcimycin || Adenine Nucleotides || Cyclic AMP || Valsartan || Purine Nucleotides || Protoporphyrins |
| Spermadhesin, CUB domain | 0.9202 | INHERITED FROM: Panobinostat |
| Polo-box duplicated region | 0.9514 | INHERITED FROM: Fluorouracil || Uracil || Genistein || Camptothecin || Leflunomide || Irinotecan |
| Enolase | 0.9514 | INHERITED FROM: Decitabine |
| Homeodomain | 0.9692 | INHERITED FROM: Chir 98014 || Panobinostat |
| ZZ domain | 1 | INHERITED FROM: dinophysistoxin 1 |
| Insulin-like | 1 | INHERITED FROM: Morpholines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Dihydropyridines || Benzimidazoles |
| Pyrin domain, PYD | 1 | INHERITED FROM: Adenosine Triphosphate |
| Gonadodropin/Follitropin | 1 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Adenine Nucleotides || Cyclic AMP || Isoquinolines || Purine Nucleotides |
| Rhodopsin-like | 1 | INHERITED FROM: Tiotropium Bromide || Dioxanes || oxotremorine M || brucine N-oxide || Pilocarpine || abanoquil || Lurasidone Hydrochloride || 7-hydroxymitragynine || Quinuclidinyl Benzilate || broxaterol || N-methylhistamine || 5-methylurapidil || 5-methylfurtrethonium || 1,3-dipropyl-8-cyclopentylxanthine || quercitrin || (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) || Org 41841 || Risperidone || Oxymetazoline || 4-diphenylacetoxy-1,1-dimethylpiperidinium || Strychnine || 7-methyl-6,7,8,9,14,15-hexahydro-5H-benz(d)indolo(2,3-g)azecine || Pipecuronium || xylometazoline || A 86929 || alfuzosin || Oxotremorine || Ketanserin || N-Methylscopolamine || Vortioxetine || proanthocyanidin || 7-fluoro-2-oxo-4-(2-(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)ethyl)-1,2-dihydroquinoline-1-aceta || Tropicamide || indole || clobenpropit || Idazoxan || Muscarine || BMY 7378 || 5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide || CGP 20712A |
| Interferons/interleukin-10 (IL-10) | 1 | INHERITED FROM: beta-Lactams || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || INCB018424 || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide || Aminoquinolines || gardiquimod || 6-formylindolo(3,2-b)carbazole || Tyrphostins |
| Eukaryotic proteases | 1 | INHERITED FROM: 4-Hydroxycoumarins || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || merbarone || Thiobarbiturates || Warfarin |
| Actin/HSP70 | 1 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || indirubin-3'-monoxime || Albendazole || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || pyrithione zinc || Hemin || Metalloporphyrins || Caffeine || Benzimidazoles || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) |
| TNF-like | 1 | INHERITED FROM: peroben || brevetoxin 2 || Phenanthridines || Quinolones || Atorvastatin || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Clozapine || Pyridones || Benzophenanthridines || Piperazines || Vemurafenib || sanguinarine || Aripiprazole || candesartan |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| beta-CASP RNA-metabolising hydrolases | 0 | Direct |
| DNase I-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| RWD domain | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Stathmin | 0 | Direct |
| AlkB-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| U-box | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Pentapeptide repeats | 0 | Direct |
| Connexin43 | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
| BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| Release factor | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Acetylcholinesterase-like | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Ornithine decarboxylase antizyme-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| Putative glucosidase YicI, domain 3 | 0 | Direct |
| BolA-like | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Alkaline phosphatase | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Tandem AAA-ATPase domain | 0 | Direct |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| A20-like zinc finger | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| Lysophospholipase | 0 | Direct |
| Plakophilin 1 helical region | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Ribosomal protein L3 | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Class I aldolase | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| FKBP immunophilin/proline isomerase | 0 | Direct |
| Hook domain | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | Direct |
| AXH domain | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Penta-EF-hand proteins | 0 | Direct |
| ALDH-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Tetratricopeptide repeat (TPR) | 0 | Direct |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | Direct |
| Synatpobrevin N-terminal domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| FF domain | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Renal dipeptidase | 0 | Direct |
| Phosducin | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| LON domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| APC10-like | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| PWWP domain | 0 | Direct |
| Bacterial PLC | 0 | Direct |
| SMAD4-binding domain of oncoprotein Ski | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Ferritin | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Uteroglobin-like | 0 | Direct |
| Complement components | 0 | Direct |
| DNA ligase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| Fibroblast growth factors (FGF) | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| DIX domain | 0 | Direct |
| Subtilases | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| DEATH effector domain, DED | 0 | Direct |
| PWI domain | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Integrin domains | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Paired domain | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Hermes transposase-like | 0 | Direct |
| CUT domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| MAPEG domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| WW domain | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| NagB-like | 0 | Direct |
| T-box | 0 | Direct |
| TK-like Pyr module | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| GAF domain | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Cytidylytransferase | 0 | Direct |
| Lipoxigenase N-terminal domain | 0 | Direct |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Multidrug resistance efflux transporter EmrE | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| FCH domain | 0 | Direct |
| Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| DLC | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Prokaryotic proteases | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Nuclear receptor | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| STAT | 0 | Direct |
| TatD Mg-dependent DNase-like | 0 | Direct |
| FucT-like | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| Metallothionein | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| MIF-related | 0 | Direct |
| Platelet-derived growth factor-like | 0 | Direct |
| Pseudouridine synthase RsuA/RluD | 0 | Direct |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| EGF-type module | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | Direct |
| Troponin T | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Selenoprotein W-related | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Trefoil | 0 | Direct |
| PUG domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Dachshund-homology domain | 0 | Direct |
| PHD domain | 0 | Direct |
| FolH catalytic domain-like | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Crotonase-like | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| SelR domain | 0 | Direct |
| Interferon regulatory factor | 0 | Direct |
| Adapter protein APS, dimerisation domain | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Flavin-binding PAS domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Ribosomal proteins L24p and L21e | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| HMGL-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Crisp domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Pointed domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Starch-binding domain | 0 | Direct |
| Transglutaminase N-terminal domain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Adenain-like | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| Leukotriene A4 hydrolase C-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| LysM domain | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Choline kinase | 0 | Direct |
| SPOC domain | 0 | Direct |
| p53 DNA-binding domain-like | 0 | Direct |
| Synapsin domain | 0 | Direct |
| Glycosyl hydrolases family 35 catalytic domain | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Tropomyosin | 0 | Direct |
| NIPSNAP | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Clathrin heavy-chain linker domain | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Tetraspanin | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Cysteine rich domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Transferrin | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| IMD domain | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| CAT-like | 0 | Direct |
| L27 domain | 0 | Direct |
| La domain | 0 | Direct |
| Thioltransferase | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| DEP domain | 0 | Direct |
| Sedlin (SEDL) | 0 | Direct |
| AAT-like | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Prefoldin | 0 | Direct |
| Short-chain cytokines | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Troponin I | 0 | Direct |
| YWTD domain | 0 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| HIN-200/IF120x domain | 0 | Direct |
| Sema domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| NagD-like | 0 | Direct |
| GLA-domain | 0 | Direct |
| Centromere-binding | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Osteonectin | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| Lectin leg-like | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| GS domain | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Triple coiled coil domain of C-type lectins | 0 | Direct |
| BRK domain-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | Direct |
| VWC domain | 0 | Direct |
| LanC-like | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| HtrA-like serine proteases | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| RUN domain | 0 | Direct |
| HkH motif-containing C2H2 finger | 0 | Direct |
| Diacylglycerol kinase-like | 0 | Direct |
| GAT domain | 0 | Direct |
| Aldo-keto reductases (NADP) | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| CUE domain | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | Direct |
| B56-like | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| MSP-like | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Notch domain | 0 | Direct |
| PUA domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
| CPH domain | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| PIWI domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Nuclear movement domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| YicI N-terminal domain-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| COMT-like | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Retinoblastoma tumor suppressor domains | 0 | Direct |
| ProC C-terminal domain-like | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| MPP-like | 0 | Direct |
| SNF-like | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| YjeF N-terminal domain-like | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| GDI-like N domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Kringle modules | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| MYND zinc finger | 0 | Direct |
| Animal lipoxigenases | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| WWE domain | 0 | Direct |
| VHS domain | 0 | Direct |
| GABARAP-like | 0 | Direct |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Oligosaccharide phosphorylase | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Arylamine N-methyltransferase | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| UBA domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| ECR1 N-terminal domain-like | 0 | Direct |
| Bee venom hyaluronidase | 0 | Direct |
| Hexokinase | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| Synapsin C-terminal domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Macro domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| C2 set domains | 0 | Direct |
| Link domain | 0 | Direct |
| Aminomethyltransferase folate-binding domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Fumble-like | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Pseudouridine synthase II TruB | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Family 1 of glycosyl hydrolase | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| PNP-oxidase like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| FAH | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| PCI domain (PINT motif) | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Reductases | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| beta-glycanases | 0 | Direct |
| Variant SAM domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Neurotrophin | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Nop domain | 0 | Direct |
| ARID domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| PB1 domain | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| BSD domain | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| WGR domain | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| LeuD-like | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| PDEase | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| UBX domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Transglutaminase core | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| SRF-like | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| SAND domain | 0 | Direct |
| Papain-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| Caspase recruitment domain, CARD | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| 5' nucleotidase-like | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | Direct |
| Integrin beta EGF-like domains | 0 | Direct |
| PKD domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| PDZ domain | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Extended AAA-ATPase domain | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| gamma-adaptin C-terminal appendage domain-like | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| Exostosin | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Synuclein | 0 | Direct |
| TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Interleukin-1 (IL-1) | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| UBC-related | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| Variant RING domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| THAP domain | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| HR1 repeat | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| SMAD domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| HD domain | 0 | Direct |
| GYF domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | Direct |
| STAT DNA-binding domain | 0 | Direct |
| Cytochrome p450 reductase N-terminal domain-like | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Tyrosine-dependent oxidoreductases | 0 | Direct |
| Cripto EGF-like domain-like | 0 | Direct |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| HCP-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| MIR domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| MBT repeat | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| CAD domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| RGC domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Pyridoxal-dependent decarboxylase | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| TK-like PP module | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Chromo domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Cullin repeat | 0 | Direct |
| GRAM domain | 0 | Direct |
| Carbamilase | 0 | Direct |
| STAR domain | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Ecto-ART | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0.001134 | Inherited |
| SH3-domain | 0.003867 | Inherited |
| Canonical RBD | 0.004846 | Inherited |
| Protein kinases, catalytic subunit | 0.007254 | Inherited |
| SH2 domain | 0.02289 | Inherited |
| Growth factor receptor domain | 0.1364 | Inherited |
| ABC transporter ATPase domain-like | 0.1512 | Inherited |
| Classic zinc finger, C2H2 | 0.1787 | Inherited |
| Mitochondrial carrier | 0.1995 | Inherited |
| Leucine zipper domain | 0.1995 | Inherited |
| Ubiquitin-related | 0.2064 | Inherited |
| Fibronectin type III | 0.2205 | Inherited |
| PX domain | 0.2288 | Inherited |
| Cadherin | 0.2353 | Inherited |
| LIM domain | 0.2453 | Inherited |
| Interleukin 8-like chemokines | 0.2623 | Inherited |
| Dual specificity phosphatase-like | 0.2623 | Inherited |
| PLC-like (P variant) | 0.271 | Inherited |
| G proteins | 0.2812 | Inherited |
| DBL homology domain (DH-domain) | 0.3225 | Inherited |
| MHC antigen-recognition domain | 0.3304 | Inherited |
| Fibrinogen C-terminal domain-like | 0.3898 | Inherited |
| cAMP-binding domain | 0.4029 | Inherited |
| Ras-binding domain, RBD | 0.4029 | Inherited |
| I set domains | 0.4063 | Inherited |
| Acetyl-CoA synthetase-like | 0.4159 | Inherited |
| Cyclin | 0.4295 | Inherited |
| FHA domain | 0.4295 | Inherited |
| Ras GEF | 0.4431 | Inherited |
| Motor proteins | 0.4452 | Inherited |
| HMG-box | 0.4856 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.5053 | Inherited |
| Hemopexin-like domain | 0.5205 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.5205 | Inherited |
| Intermediate filament protein, coiled coil region | 0.5361 | Inherited |
| Myosin rod fragments | 0.5371 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.5371 | Inherited |
| Integrin A (or I) domain | 0.5537 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.5659 | Inherited |
| Laminin-type module | 0.5731 | Inherited |
| Frizzled cysteine-rich domain | 0.5731 | Inherited |
| UDPGT-like | 0.5731 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5783 | Inherited |
| MMP N-terminal domain | 0.5921 | Inherited |
| Proteasome subunits | 0.5921 | Inherited |
| Glutathione peroxidase-like | 0.612 | Inherited |
| S100 proteins | 0.6318 | Inherited |
| Arylsulfatase | 0.6318 | Inherited |
| GABA-aminotransferase-like | 0.6512 | Inherited |
| F-box domain | 0.6582 | Inherited |
| Crystallins/Ca-binding development proteins | 0.6725 | Inherited |
| C1 set domains (antibody constant domain-like) | 0.6826 | Inherited |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.6952 | Inherited |
| Serpins | 0.6967 | Inherited |
| Nucleosome core histones | 0.6969 | Inherited |
| PDI-like | 0.7181 | Inherited |
| Globins | 0.7181 | Inherited |
| Long-chain cytokines | 0.7181 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.7181 | Inherited |
| Fibronectin type II module | 0.7411 | Inherited |
| RING finger domain, C3HC4 | 0.7431 | Inherited |
| Amylase, catalytic domain | 0.7653 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.7653 | Inherited |
| Hairy Orange domain | 0.7886 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.7886 | Inherited |
| Anticodon-binding domain of Class II aaRS | 0.7886 | Inherited |
| ets domain | 0.7939 | Inherited |
| Voltage-gated potassium channels | 0.7968 | Inherited |
| LDL receptor-like module | 0.8296 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0.8403 | Inherited |
| Ngr ectodomain-like | 0.8585 | Inherited |
| L domain | 0.8671 | Inherited |
| Glycerol-3-phosphate transporter | 0.8671 | Inherited |
| KRAB domain (Kruppel-associated box) | 0.8792 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.8906 | Inherited |
| TRASH domain | 0.8947 | Inherited |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0.8947 | Inherited |
| Transforming growth factor (TGF)-beta | 0.9099 | Inherited |
| Spermadhesin, CUB domain | 0.9202 | Inherited |
| Polo-box duplicated region | 0.9514 | Inherited |
| Enolase | 0.9514 | Inherited |
| Homeodomain | 0.9692 | Inherited |
| ZZ domain | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| Pyrin domain, PYD | 1 | Inherited |
| Gonadodropin/Follitropin | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Interferons/interleukin-10 (IL-10) | 1 | Inherited |
| Eukaryotic proteases | 1 | Inherited |
| Actin/HSP70 | 1 | Inherited |
| TNF-like | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| PapD-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Amine oxidase N-terminal region | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| HIN-2000 domain-like | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| BTG domain-like | 0 | DIRECT |
| Hermes dimerisation domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | DIRECT |
| Uteroglobin-like | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| FnI-like domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Pseudouridine synthase | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Metallothionein | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Pentapeptide repeat-like | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Triple coiled coil domain of C-type lectins | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Anaphylotoxins (complement system) | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| Probable bacterial effector-binding domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| FKBP-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| GAF domain-like | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| RILP dimerisation region | 0 | DIRECT |
| YjeF N-terminal domain-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Phenylalanine zipper | 0 | DIRECT |
| GTF2I-like repeat | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| GTPase activation domain, GAP | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Integrin beta tail domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Cytochrome c oxidase subunit h | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Lipoxigenase | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| FAH | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Amine oxidase catalytic domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| PH domain-like | 0.000004951 | DIRECT |
| SH3-domain | 0.002875 | INHERITED FROM: ponatinib || AG 1879 || Azoles || aflatoxin B2 || Pyridazines |
| Protein kinase-like (PK-like) | 0.003748 | INHERITED FROM: Anthocyanins || ponatinib || bisindolylmaleimide I || Iridoids || Sunitinib || Pyocyanine || Quinoxalines || dihydromyricetin || SU 6656 || Pyrroles || Imatinib Mesylate || 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbo || isoquercitrin || orantinib || WHI P154 || 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline || fisetin || quercetin 4'-O-glucopyranoside || Benzopyrans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Folfox protocol || Chromones || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Dioxoles || bisindolylmaleimide || deguelin || Niacinamide || Ochratoxins || LM-1685 || Sorafenib || Nicotinic Acids || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || Rimonabant || Heterocyclic Compounds, 3-Ring || Naphthyridines || 2''-galloylhyperin || Benzoxazines || Indolizines || NVP-TAE684 || Pyridones || trametinib || Lactams || ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate || abemaciclib || Isoquinolines || Trifluoperazine || Adenosine Diphosphate || dehydroglyasperin C || Quinazolines || Maytansine || fascaplysine || 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy || carboxyamido-triazole || Orotic Acid || SU 5402 || Pyrans || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine || Benzothiazoles || alsterpaullone || Camptothecin || Win 55212-2 || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || Oxazines || 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol || Phenazines || Pyridines || Thiazoles || GSK 1363089 || Morpholines || Citrinin || APS-2-79 || AG 1879 || Polyphenols || pifithrin || Maleimides || dictamnine || Quinolines || Piperidines || Isoindoles || GSK2110183 || Dioxolanes || Staurosporine || tylophorine || indole-5-carboxamide || Acids, Heterocyclic || 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone || A 419259 || Celecoxib || Imidazoles || didymin || dracorhodin || N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3- || ON123300 || Solanaceous Alkaloids || GSK2141795 || 6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one || ZSTK474 || Pyrazines || N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide || 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide || Chromans || PD 173074 || Carbazoles || Dasatinib || Flavones || Piperazines || 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone || staurosporine aglycone || 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione || Cyclic GMP || 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine || Capsaicin || Coumarins || NVP-AEW541 || Iridoid Glycosides || baricitinib || 4-acetylantroquinonol B || 6-(methylamino)pyrido(3,4-d)pyrimidine || Xanthenes || 103D5R || 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide || Azoles || BMS 754807 || 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione || Pyrimidines || tanespimycin || Benzimidazoles || Cantharidin || 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine || 5-iodo-3-(2-azetidinylmethoxy)pyridine || AG-012986 || 5-iodotubercidin || Tocopherols || napabucasin || PI103 || fumosorinone || Alkaloids || aflatoxin B2 || Benzodioxoles || NVP ADW742 || ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate || aucubin || alvocidib || Aminopyridines || baohuoside I || Tubercidin || Indoles || Pyridazines || labedipinedilol A || esculetin || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || rutacarpine || WY-135 || coptisine || 6,7-dimethoxy-3-phenylquinoxaline || rottlerin || Semaxinib || 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone || Indazoles || ML 9 || norcantharidin || 1',2'-dihydrorotenone || copper-1,10-phenanthroline || Y 27632 || Sterigmatocystin || Lactams, Macrocyclic || PKI 166 || PI 620 || 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione |
| P-loop containing nucleoside triphosphate hydrolases | 0.00543 | INHERITED FROM: mesaconitine || pitavastatin || Coumestrol || Thiazines || macitentan || Thioxanthenes || Elacridar || Risedronic Acid || verlukast || 5-carboxyfluorescein diacetate || Pyrans || Furans || Vinca Alkaloids || calcein AM || 2,3-bis(3'-hydroxybenzyl)butyrolactone || Dioxolanes || TAK-875 || 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)a || 4-Butyrolactone || 5(6)-carboxy-2',7'-dichlorofluorescein || fluorexon || Phosphoadenosine Phosphosulfate || AC 93253 || benzoylhypaconine || Xanthenes || Tolvaptan || bisbenzimide ethoxide trihydrochloride || Guanosine Triphosphate |
| FYVE/PHD zinc finger | 0.008159 | INHERITED FROM: 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide || Dioxoles || dorsomorphin |
| EGF/Laminin | 0.01004 | INHERITED FROM: batimastat || Cytidine || Quinoxalines || Dioxoles || dorsomorphin || Heterocyclic Compounds, 3-Ring || NVP-TAE684 || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Pteridines || Pyridines || Thiazoles || Dioxins || Imidazoles || Dasatinib || 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine || SC 560 || Cyclic S-Oxides || Propylthiouracil || GSK1210151A || Heterocyclic Oxides || Tetrachlorodibenzodioxin || aflatoxin B2 || Aminopyridines || Etodolac |
| RNA-binding domain, RBD | 0.01203 | INHERITED FROM: Vitamin E || Vinca Alkaloids || yessotoxin || ((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one) || ICG 001 || Pyrazoles || PP242 || pateamine A |
| SH2 domain | 0.01931 | INHERITED FROM: ponatinib || Flavonoids || N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine || Imatinib Mesylate || isoquercitrin || Methylthiouracil || tofacitinib || INCB018424 || Niacinamide || Heterocyclic Compounds, 3-Ring || Carbamazepine || alpinumisoflavone || AG 1879 || Polyphenols || Piperidines || stattic || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Imidazoles || Dasatinib || Thiouracil || Triazoles || WP1066 || (+)-JQ1 compound || baricitinib || 4-acetylantroquinonol B || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || Azepines || Azoles || AZD 1480 || N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidine || 4'-methoxy licoflavanone || Pyridazines || norcantharidin || 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.02064 | INHERITED FROM: cerivastatin || Dihydropyridines || kaempferol || manidipine || chlormidazole || rubitecan || Flavonoids || pazopanib || Miconazole || prochloraz || muraglitazar || Silybin || triflumizol || metoprine || norathyriol || 1,5-benzothiazepine || 1,4-bis(2-(3,5-dichloropyridyloxy))benzene || biochanin A || pyridaben || pitavastatin || terbutylazine || daidzein || fenpyroximate || Dioxoles || laurolactam || ST 1481 || propiconazole || Benzoxazines || lacidipine || Lactams || Ro 41-5253 || Isoquinolines || fenarimol || fludioxonil || Azetines || GW 501516 || ZK 216348 || 2-acetylphenothiazine || cilnidipine || quinoxyfen || Pyrans || osajin || GKT137831 || Heterocyclic Compounds, 4 or More Rings || Reserpine || Aminoacridines || Pyridines || Thiazoles || LY 518674 || Quinolines || Trifluridine || Staurosporine || Benzothiepins || piperophos || Thiepins || pomiferin || vinclozolin || 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one || isoprothiolane || 2-methyl-c-5-(4-(5-methyl-2-(4-methylphenyl)-4-oxazolyl)butyl)-1,3-dioxane-r-2-carboxylic acid || Ciclopirox || Nebivolol || 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime || Kaempferols || Oxazoles || icaritin || Adenine Nucleotides || tegaserod || Proflavine || enilconazole || Azoles || Emetine || Pyrimidines || TRAM 34 || 3-methylquercetin || Dioxanes || iprodione || Alkaloids || Acridines || 4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid || cyprodinil || irilone || Pyridazines || triadimefon || 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine || galaxolide || Dronedarone || Lactams, Macrocyclic || 1,4-dihydropyridine || Pyrimethamine || Purine Nucleotides || Benomyl || flavone || Thiazepines |
| Ubiquitin-like | 0.03174 | INHERITED FROM: ABT-737 || 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || ZSTK474 |
| ARM repeat | 0.04231 | INHERITED FROM: 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || ZSTK474 |
| Cysteine proteinases | 0.0499 | INHERITED FROM: benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide |
| beta-beta-alpha zinc fingers | 0.05559 | INHERITED FROM: Aflatoxin M1 || Leflunomide || pomalidomide || Benzazepines || GSK-J4 || Isoxazoles |
| NAD(P)-binding Rossmann-fold domains | 0.07484 | INHERITED FROM: Cimetidine || NADP || Heterocyclic Compounds, 3-Ring || NAD || K 7174 || Metyrapone || Dioxins || GW 4064 || fipronil || Adenine Nucleotides || Fomepizole || Oxcarbazepine || Isatin || Purines || Purine Nucleotides |
| Galactose-binding domain-like | 0.07793 | INHERITED FROM: ponatinib || Indoles || Pyridazines |
| Nucleic acid-binding proteins | 0.0808 | INHERITED FROM: cryptolepine || Thiazines || Furans || Bortezomib || 4-Butyrolactone || Chromans || Coumarins || Tunicamycin || Piroxicam |
| E set domains | 0.1099 | INHERITED FROM: 6-isopropoxy-9-oxoxanthene-2-carboxylic acid || scoparone || Harmala Alkaloids || piperine || Benzoxazoles || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || Calcimycin || Carbolines |
| Growth factor receptor domain | 0.1544 | INHERITED FROM: ponatinib || Troglitazone || Folfox protocol || Dioxoles || dorsomorphin || Heterocyclic Compounds, 3-Ring || NVP-TAE684 || Quinazolines || Pteridines || Canertinib || Pyridines || Thiazoles || Imidazoles || CMF regimen || Formyltetrahydrofolates || Dasatinib || Flavones || Adenine Nucleotides || baicalin || NVP-AEW541 || Cyclic S-Oxides || 6-(methylamino)pyrido(3,4-d)pyrimidine || Azoles || Pyrimidines || Heterocyclic Oxides || napabucasin |
| FAD/NAD(P)-binding domain | 0.1611 | INHERITED FROM: senkirkine || Thioctic Acid || pyrithione zinc || Benzoflavones || Pyrrolizidine Alkaloids || Methimazole || Azoles || Purine Nucleosides || Benzydamine || Indazoles |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.1641 | INHERITED FROM: 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1 || Pyrans || N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide || ZSTK474 || aflatoxin B2 || Aminopyridines |
| (Trans)glycosidases | 0.167 | INHERITED FROM: Oxocins || yessotoxin || PP242 |
| Mitochondrial carrier | 0.1729 | INHERITED FROM: Adenosine Triphosphate || Stavudine || Tunicamycin || Thymidine || Atrazine || Triazines |
| Leucine zipper domain | 0.1791 | INHERITED FROM: O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate || Flavonoids || cylindrospermopsin || Tropanes || Quinoxalines || Leflunomide || fisetin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Hemin || Dioxoles || Penicillin G || Ochratoxins || Rimonabant || Heterocyclic Compounds, 3-Ring || Carbamazepine || Benzofurans || 9-methoxycamptothecin || Isoquinolines || Quinazolines || Uric Acid || Pteridines || Aminopterin || Cyclic AMP || SB 203580 || Pyrrolidines || dinophysistoxin 1 || quinomethionate || Heterocyclic Compounds, 4 or More Rings || Oxazines || Vinca Alkaloids || 4-Quinolones || Phenanthrolines || Pyridines || Citrinin || Maleimides || Quinolines || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Isoindoles || Acids, Heterocyclic || Tetrazoles || Dioxins || Imidazoles || alpha-Tocopherol || Phthalimides || Penicillins || Pyrimidine Nucleosides || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Pyrazines || Tetrapyrroles || Piperazines || Oxazoles || piperine || Isoxazoles || CP 31398 || Pyrazinamide || Azepines || Indole Alkaloids || Azoles || Anisomycin || Cocaine || NSC668394 || Nifedipine || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Tetrachlorodibenzodioxin || Phenobarbital || Quercetin || Benzodioxoles || Indoles || sauchinone || BIX 02189 || rottlerin || 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)am || nefazodone || SR 144528 |
| SMAD/FHA domain | 0.1791 | INHERITED FROM: Cytochalasins || Iridoids || LY2109761 || Iridoid Glucosides || INCB018424 || fludarabine || LDN 193189 || galangin || osthol || Polyphenols || Vidarabine || Iridoid Glycosides || casticin || aucubin || Cytochalasin D |
| PX domain | 0.1857 | INHERITED FROM: Go 6976 |
| Cadherin-like | 0.1978 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
| Fibronectin type III | 0.1991 | INHERITED FROM: ponatinib || Cytidine || Dioxoles || dorsomorphin || Panobinostat || Pyridines || aflatoxin B2 || Aminopyridines |
| SET domain | 0.2216 | INHERITED FROM: Benzylisoquinolines || Berberine || Isoquinolines || Berberine Alkaloids |
| Interleukin 8-like chemokines | 0.2372 | INHERITED FROM: Phenanthridines || Tropanes || Imatinib Mesylate || 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline || Puromycin || 7-bromoindirubin-3'-oxime || Troglitazone || Dequalinium || 3'-methoxy-4'-nitroflavone || tofacitinib || BIRB 796 || gemcitabine || Telmisartan || 1-carboxyheptylimidazole || Albendazole || 6-formylindolo(3,2-b)carbazole || Pterins || E804 bisindole || Oxazolone || Quinolinium Compounds || palmatine || fexofenadine || Pteridines || PD168393 || Aminopterin || Roflumilast || SB 203580 || Pyrrolidines || Vinca Alkaloids || pevonedistat || Demecolcine || Terfenadine || amorolfine || Thiazoles || Polyphenols || Opiate Alkaloids || Quinolines || Piperidines || Ritonavir || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Lopinavir || Imidazoles || Rutin || coralyne || Allopurinol || Aripiprazole || Dasatinib || Oxypurinol || Flavones || Piperazines || captax || Quinolones || Benzoxazoles || 6,2',4'-trimethoxyflavone || Anisomycin || Cocaine || Emetine || Hesperidin || Benzimidazoles || roflumilast N-oxide || Morphinans || Calcimycin || Morphine Derivatives || Deoxycytidine || Azabicyclo Compounds || Itraconazole || Propidium || Secologanin Tryptamine Alkaloids || Colchicine || 2-methyl-4-isothiazolin-3-one || luliconazole |
| p53-like transcription factors | 0.2456 | INHERITED FROM: Cytochalasins || 4-Hydroxycoumarins || Anthocyanins || bisindolylmaleimide I || myricetin || Imatinib Mesylate || isoquercitrin || fisetin || goniothalamin || piperlonguminine || Imidazolines || scoparone || tofacitinib || INCB018424 || Nitrofurans || Thioctic Acid || Niacinamide || Nicotinic Acids || Resveratrol || Pyridones || alpinumisoflavone || Tyrphostins || calyculin A || Benzothiazoles || Harmala Alkaloids || Ergolines || 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine || Vinca Alkaloids || pevonedistat || Phenanthrolines || Terfenadine || Temozolomide || Imidazolidines || Thiazoles || Morpholines || Pergolide || AG 1879 || Polyphenols || Maleimides || Piperidines || Ritonavir || Umbelliferones || Nicotine || Isoindoles || Staurosporine || Benzodiazepinones || Acids, Heterocyclic || Dicumarol || Ellagic Acid || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Tetrazoles || Imidazoles || Dactinomycin || Flavanones || SRT2183 || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Apigenin || Carbazoles || Flavones || Kaempferols || Thiouracil || Triazoles || Piperazines || pyrrolidine dithiocarbamic acid || piperine || Azepines || Benzoxazoles || Ergot Alkaloids || Morphine || alpha-naphthoflavone || Benzodioxoles || AZD 1480 || 4'-methoxy licoflavanone || Luteolin || Calcimycin || Morphine Derivatives || Carbolines || esculetin || norcantharidin || Y 27632 || chrysin || Chloroquine |
| PLP-dependent transferases | 0.2638 | INHERITED FROM: Picolines || Vitamin B 6 || K 7174 || adefovir dipivoxil || Dioxins || Tetrachlorodibenzodioxin |
| (Phosphotyrosine protein) phosphatases II | 0.275 | INHERITED FROM: Leflunomide |
| Periplasmic binding protein-like I | 0.2918 | INHERITED FROM: Citalopram |
| Thioredoxin-like | 0.2919 | INHERITED FROM: triflumizol || Quinidine || darbufelone || desethylamodiaquine || Kathon 930 || Thioctic Acid || amodiaquine quinoneimine || dinophysistoxin 1 || apple polyphenol extract || Paraquat || captafol || Nevirapine || KT 5720 || Tetrapyrroles || 2-n-octyl-4-isothiazolin-3-one || Pyridinium Compounds || Bile Pigments || Cinchona Alkaloids || fluazinam || xanthohumol || Chlorophyllides || Thiazolidines || Amodiaquine || Captan |
| DBL homology domain (DH-domain) | 0.2948 | INHERITED FROM: aflatoxin B2 || Aminopyridines |
| MHC antigen-recognition domain | 0.3021 | INHERITED FROM: Thiazines || entinostat || Penicillin G || Cephalosporins || Lactams || Quinazolines || Fluoroquinolones || Gefitinib || Quinolines || Ampicillin || Lincosamides || Benzothiadiazines || Diltiazem || beta-Lactams || valdecoxib || MRK 003 || Chlorothiazide || Cyclic S-Oxides || 2-Pyridinylmethylsulfinylbenzimidazoles || Ketorolac || Heterocyclic Oxides || Omeprazole |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.3094 | INHERITED FROM: cylindrospermopsin || procyanidin B2 || S-Adenosylmethionine || Berberine Alkaloids || Pyrrolizidine Alkaloids |
| vWA-like | 0.32 | INHERITED FROM: 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Atorvastatin || Phenytoin |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3227 | INHERITED FROM: Hydralazine || EGFR tyrosine kinase inhibitor 324674 || stattic || Cyclic S-Oxides || Heterocyclic Oxides || Phthalazines || quercitrin |
| Fibrinogen C-terminal domain-like | 0.3581 | INHERITED FROM: Adenosine Diphosphate |
| Alkaline phosphatase-like | 0.3698 | INHERITED FROM: Oxocins || yessotoxin || PP242 |
| Ras GEF | 0.3824 | INHERITED FROM: Methapyrilene |
| Acetyl-CoA synthetase-like | 0.3824 | INHERITED FROM: Dioxins || GW 4064 || Pyrrolizidine Alkaloids || 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime || Tetrachlorodibenzodioxin |
| Toll/Interleukin receptor TIR domain | 0.4382 | INHERITED FROM: 7-bromoindirubin-3'-oxime || E804 bisindole || Erlotinib Hydrochloride || Quinolines || Piperidines || Bortezomib || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Aripiprazole || Piperazines || 6,2',4'-trimethoxyflavone || chrysin |
| Kringle-like | 0.4382 | INHERITED FROM: Hydantoins || kaempferol || Iridoids || Silybin || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || 3-hydroxyflavone || Benzoxazines || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Atorvastatin || Quinazolines || Pyrrolidines || Oxazines || Pyridines || Imidazolidines || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Chlorpromazine || Nicotine || carbendazim || Porphyrins || genipin || Acids, Heterocyclic || baicalein || Dactinomycin || Flavanones || Solanaceous Alkaloids || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tetrapyrroles || Phenytoin || Apigenin || Benzodiazepines || Chalcones || 3,3'-diindolylmethane || Tocopherols || GSK1210151A || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzophenanthridines || Y 27632 || chrysin || Benomyl |
| HMG-box | 0.45 | INHERITED FROM: Polyphenols |
| Voltage-gated potassium channels | 0.4513 | INHERITED FROM: Flecainide || Tetrodotoxin || N-(1-(3-morpholin-4-ylphenyl)ethyl)-3-phenylacrylamide || Astemizole || N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)ac || Niflumic Acid || Mibefradil || nefazodone |
| HSP20-like chaperones | 0.4533 | INHERITED FROM: N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || Adenosine Triphosphate |
| Class II aaRS and biotin synthetases | 0.4533 | INHERITED FROM: Cidofovir || Cytosine |
| Myosin rod fragments | 0.4533 | INHERITED FROM: Dihydropyridines || Nifedipine |
| TNF receptor-like | 0.4686 | INHERITED FROM: HhAntag691 || sanguinarine || gemcitabine || fludarabine || Fluorouracil || Quinazolines || Pteridines || Pyrrolidines || osthol || Paraquat || Demecolcine || Polyphenols || Quinolines || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Isoindoles || Celecoxib || Imidazoles || Pentoxifylline || Vidarabine || Genistein || Solanaceous Alkaloids || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Theobromine || Aripiprazole || Thiophenes || Flavones || Pyridinium Compounds || Piperazines || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Quinolones || motexafin gadolinium || Azepines || Vemurafenib || Benzophenanthridines || licochalcone A |
| Metalloproteases ("zincins"), catalytic domain | 0.4699 | INHERITED FROM: 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || benazepril || RTKI cpd || Amitrole || deguelin || Picolinic Acids || 3-hydroxypicolinic acid || Tyrphostins || omapatrilat || manganese(III)-tetrakis(4-benzoic acid)porphyrin || CGS 27023A || Thiepins || Tetrazoles || Phenytoin || varespladib methyl || piperine || dieckol || BQ 788 || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || Dioxanes || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || Benomyl || Thiazepines |
| Hemopexin-like domain | 0.4829 | INHERITED FROM: Hydantoins || Benzylisoquinolines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Silybin || Quinoxalines || Flavonolignans || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Amitrole || Berberine || deguelin || salinomycin || Picolinic Acids || 3-hydroxypicolinic acid || Aminoimidazole Carboxamide || pyrazolo(3,4-d)pyrimidine || Quinazolines || Tyrphostins || SB 203580 || Pyrrolidines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || CGS 27023A || Oxazines || AICA ribonucleotide || Morpholines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Dioxolanes || Porphyrins || Acids, Heterocyclic || Solanaceous Alkaloids || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tetrapyrroles || Phenytoin || Carbazoles || varespladib methyl || piperine || dieckol || BQ 788 || Benzodiazepines || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || Dioxanes || Purine Nucleosides || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Deoxycytidine || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || Y 27632 || 2-methyl-4-isothiazolin-3-one || chrysin || Ciprofloxacin |
| Cystatin/monellin | 0.4829 | INHERITED FROM: Thioxanthenes || Lucanthone |
| Intermediate filament protein, coiled coil region | 0.4988 | INHERITED FROM: flavone |
| Immunoglobulin | 0.5128 | INHERITED FROM: ponatinib || orantinib || HX 630 || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || 3,5-di-tert-butylchalcone 4'-carboxylic acid || Cephalosporins || gardiquimod || Lincosamides || Benzothiadiazines || beta-Lactams || thieno(2,3-c)isoquinolin-5-one || Aripiprazole || Triazoles || (+)-JQ1 compound || Ketorolac || Lenalidomide |
| Nicotinic receptor ligand binding domain-like | 0.528 | INHERITED FROM: Benzylisoquinolines || Tropanes || Atropine || Pentobarbital || Etomidate || 1-(4-methoxyphenyl)piperazine || Bicuculline || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Pentylenetetrazole || tert-butylbicyclo-2-benzoate || Isoquinolines || 1-(2-methoxyphenyl)piperazine || Ro 15-4513 || epibatidine || Muscimol || Nicotine || Heterocyclic Compounds, Bridged-Ring || 1-(3-chlorophenyl)piperazine || desformylflustrabromine || Diterpene Alkaloids || Dimethylphenylpiperazinium Iodide || Quinolizines || methyllycaconitine || CL 218872 || Solanaceous Alkaloids || fipronil || L 663581 || gabazine || Piperazines || Bemegride || Benzodiazepines || loreclezole || Azocines || 1-(3-trifluoromethylphenyl)piperazine || 1-benzylpiperazine || Zolpidem || cisatracurium || Lobeline || tert-butylbicyclophosphorothionate || Tubocurarine || Mivacurium || Azabicyclo Compounds || Atracurium || phenylpiperazine || 1-(4-chlorophenyl)piperazine || bretazenil || Dihydro-beta-Erythroidine || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || pozanicline |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.528 | INHERITED FROM: Hydantoins || 4-Hydroxycoumarins || kaempferol || glabridin || lorcaserin || muraglitazar || Silybin || 7-hydroxy-4-trifluoromethylcoumarin || sitafloxacin || biochanin A || fisetin || Flavonolignans || daidzein || grepafloxacin || hydroxyphenytoin || Moxifloxacin || Ofloxacin || naringenin || Hymecromone || formononetin || Phloretin || Furocoumarins || Azetines || Indoleacetic Acids || auriculasin || galangin || Biflavonoids || bropirimine || Fluoroquinolones || puerarin || Opiate Alkaloids || Umbelliferones || ranirestat || MK-0524 || Benzodiazepinones || Dioxins || 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine || Flavanones || amentoflavone || Benzoflavones || Phenytoin || Pyrazolones || Pyrrolizidine Alkaloids || Apigenin || 7-hydroxy-4-(trifluoromethyl)coumarin || Kaempferols || Loratadine || 7,3'-dihydroxy-4'-methoxyisoflavone || Benzodiazepines || Cyproheptadine || 2-Pyridinylmethylsulfinylbenzimidazoles || 2',4'-dihydroxychalcone || Benzimidazoles || Chalcones || Ezetimibe || Oxazepam || Morphine || Warfarin || Scopoletin || morin || Tetrachlorodibenzodioxin || Phenobarbital || ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate || naringenin chalcone || Amobarbital || Equol || Morphinans || Morphine Derivatives || mangiferin || Phenylbutazone || Indoprofen || Omeprazole || Etodolac || beta-Naphthoflavone || 3-hydroxydesloratadine || 2',5'-dihydroxychalcone || licochalcone A || Cotinine || bergamottin || chrysin |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.528 | INHERITED FROM: Benzylisoquinolines || Tropanes || Atropine || Pentobarbital || Etomidate || 1-(4-methoxyphenyl)piperazine || Bicuculline || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Pentylenetetrazole || tert-butylbicyclo-2-benzoate || Isoquinolines || 1-(2-methoxyphenyl)piperazine || Ro 15-4513 || epibatidine || Muscimol || Nicotine || Heterocyclic Compounds, Bridged-Ring || 1-(3-chlorophenyl)piperazine || desformylflustrabromine || Diterpene Alkaloids || Dimethylphenylpiperazinium Iodide || Quinolizines || methyllycaconitine || CL 218872 || Solanaceous Alkaloids || fipronil || L 663581 || gabazine || Piperazines || Bemegride || Benzodiazepines || loreclezole || Azocines || 1-(3-trifluoromethylphenyl)piperazine || 1-benzylpiperazine || Zolpidem || cisatracurium || Lobeline || tert-butylbicyclophosphorothionate || Tubocurarine || Mivacurium || Azabicyclo Compounds || Atracurium || phenylpiperazine || 1-(4-chlorophenyl)piperazine || bretazenil || Dihydro-beta-Erythroidine || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || pozanicline |
| Frizzled cysteine-rich domain | 0.5351 | INHERITED FROM: Theophylline || deguelin || Carbamazepine || Panobinostat || Pyridines || 1-Methyl-3-isobutylxanthine |
| PGBD-like | 0.5537 | INHERITED FROM: Hydantoins || Benzylisoquinolines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Silybin || Quinoxalines || Flavonolignans || RTKI cpd || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Amitrole || Isoflavones || deguelin || salinomycin || Picolinic Acids || 3-hydroxypicolinic acid || Aminoimidazole Carboxamide || Quinazolines || Pteridines || Tyrphostins || Aminopterin || SB 203580 || Pyrrolidines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || CGS 27023A || Oxazines || AICA ribonucleotide || Morpholines || Thiadiazoles || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Nicotine || Dioxolanes || Porphyrins || Acids, Heterocyclic || Solanaceous Alkaloids || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tetrapyrroles || Xanthones || Phenytoin || Carbazoles || Triazoles || varespladib methyl || piperine || dieckol || BQ 788 || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || Dioxanes || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Deoxycytidine || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || Y 27632 || 2-methyl-4-isothiazolin-3-one || chrysin || Ciprofloxacin |
| MFS general substrate transporter | 0.5672 | INHERITED FROM: Cimetidine || Rifamycins || nitenpyram || pseudoisocyanine || Quinidine || Flecainide || acetamiprid || 7-(deoxyadenosin-N(6)-yl)aristolactam I || Heterocyclic Compounds, 3-Ring || 2-amino-3,4-dimethylimidazo(4,5-f)quinoline || 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine || Rifampin || Lactams || Atorvastatin || Phloretin || Nortropanes || Imipramine || Uric Acid || N(1)-methylnicotinamide || Heterocyclic Compounds, 4 or More Rings || Famotidine || Ethidium || Belladonna Alkaloids || Ipratropium || imidacloprid || Thiazoles || Fluoresceins || Cephalexin || 6-carboxyfluorescein || Clonidine || Quinolizines || trospium chloride || Imidazoles || Pyrimidine Nucleosides || Neonicotinoids || Formyltetrahydrofolates || 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Cinchona Alkaloids || Ranitidine || repaglinide || Quinine || Carbolines || Serotonin || Rosuvastatin Calcium || 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide || thiacloprid || Mirtazapine || Ceftibuten || Thymidine || Lactams, Macrocyclic || Cytochalasin B |
| Cyclin-like | 0.578 | INHERITED FROM: Dihydropyridines || 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone || Phenanthridines || cryptolepine || scriptaid || Silybin || Isoniazid || Atropine || Quinoxalines || goniothalamin || Thiazines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Ochratoxins || Nicotinic Acids || fludarabine || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || Indolizines || Pyridones || Ro 41-5253 || abemaciclib || Fluorouracil || pyrazolo(3,4-d)pyrimidine || Hypoxanthines || Quinazolines || Tyrphostins || Zidovudine || calyculin A || Roscovitine || Benzothiazoles || Camptothecin || THRX 165724 || Bridged Bicyclo Compounds, Heterocyclic || Oxazines || 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-d || Aminoacridines || Guanine || Ethidium || Letrozole || Atropine Derivatives || Thiazoles || Morpholines || Citrinin || Quinolines || Ritonavir || Nicotine || Heterocyclic Compounds, Bridged-Ring || Zalcitabine || tylophorine || Acids, Heterocyclic || Celecoxib || Flavanones || ON123300 || N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea || Solanaceous Alkaloids || Lamivudine || ircinin-1 || Chromans || Pyrimidinones || MK-886 || AC 93253 || palbociclib || Isonicotinic Acids || Piperazines || Oxazoles || 7,3'-dihydroxy-4'-methoxyisoflavone || 6-(methylamino)pyrido(3,4-d)pyrimidine || Vemurafenib || Benzimidazoles || LG 100268 || Tocopherols || Acridines || Trabectedin || alvocidib || Deoxycytidine || labedipinedilol A || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || rottlerin || Indazoles || CP-654577 || Thymidine || 1',2'-dihydrorotenone || Piroxicam |
| DEATH domain | 0.5862 | INHERITED FROM: Flavonoids || Phenanthridines || echimidine || Miransertib || 5-phenylselenylmethyl-2'-deoxyuridine || Imatinib Mesylate || MitoTEMPO || fisetin || Flavonolignans || indole-3-carbinol || goniothalamin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || HhAntag691 || sanguinarine || idelalisib || Thioctic Acid || Riluzole || Sorafenib || Picolinic Acids || fludarabine || Benzoxazines || Pterins || quinoline-val-asp(OMe)-CH2-OPH || Indolizines || Benzofurans || Cladribine || 9-methoxycamptothecin || Isoquinolines || rubimaillin || polyphenon E || Quinazolines || Indoleacetic Acids || Pteridines || auriculasin || pyrithione zinc || Pyrrolidines || Uridine || 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid || Benzothiazoles || osthol || Heterocyclic Compounds, 4 or More Rings || Win 55212-2 || Nigericin || Paraquat || Oxazines || brevetoxin 2 || Oxocins || Guanine || Terfenadine || Pyridines || Polyphenols || Quinolines || Piperidines || Adenosine || Umbelliferones || Bortezomib || Isoindoles || Staurosporine || Porphyrins || 5-methylselenylmethyl-2'-deoxyuridine || tylophorine || Benzodiazepinones || Acids, Heterocyclic || Quinazolinones || Clonidine || Celecoxib || Imidazoles || Dactinomycin || Flavanones || SRT2183 || dracorhodin || Pentoxifylline || Vidarabine || Genistein || Phthalimides || ON123300 || Solanaceous Alkaloids || Dipyridamole || N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide || Pyrones || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Pyrazines || Allopurinol || ircinin-1 || 10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one || Tetrapyrroles || Fusaric Acid || Theobromine || Thiophenes || Apigenin || Carbazoles || Flavones || Pyridinium Compounds || Triazoles || Piperazines || 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide || beta-solamarine || EKB 569 || 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone || Quinolones || Capsaicin || Azepines || gardenin B || Vemurafenib || Chalcones || Cantharidin || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || nutlin 3 || tetrandrine || casticin || Purine Nucleosides || Tocopherols || morin || Quercetin || Bendamustine Hydrochloride || Calcimycin || alvocidib || Deoxycytidine || Adenine || esculetin || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || lonafarnib || 4-methylene-2-octyl-5-oxofuran-3-carboxylic acid || Benzophenanthridines || SM 164 || STF 083010 || CFM 1 || norcantharidin || Y 27632 || abexinostat || KN 62 || Ciprofloxacin |
| F-box domain | 0.5885 | INHERITED FROM: Pyrroles |
| cAMP-binding domain-like | 0.6167 | INHERITED FROM: N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide |
| Histone-fold | 0.6224 | INHERITED FROM: Benzylisoquinolines || Coumestrol || Glutethimide || Thioxanthenes || Berberine || Isoquinolines || Heterocyclic Compounds, 4 or More Rings || Furans || Demecolcine || OTX015 || 2,3-bis(3'-hydroxybenzyl)butyrolactone || Berberine Alkaloids || 4-Butyrolactone || Xanthones || Folic Acid || Triazoles || Coumarins || (+)-JQ1 compound || Azepines || Xanthenes || Lucanthone || Colchicine |
| Terpenoid cyclases/Protein prenyltransferases | 0.6331 | INHERITED FROM: Olanzapine || Benzodiazepines |
| gamma-Crystallin-like | 0.6331 | INHERITED FROM: tebuconazole |
| "Winged helix" DNA-binding domain | 0.6427 | INHERITED FROM: Harmala Alkaloids || Harmine || Lucanthone |
| Serpins | 0.6431 | INHERITED FROM: Rifampin || periodate-oxidized adenosine || Polychlorinated Dibenzodioxins || Dioxins || Benzoflavones || Tetrachlorodibenzodioxin |
| Translation proteins SH3-like domain | 0.655 | INHERITED FROM: Vitamin E |
| Snake toxin-like | 0.6569 | INHERITED FROM: rutecarpine |
| Globin-like | 0.6775 | INHERITED FROM: tebuconazole |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.6775 | INHERITED FROM: dinophysistoxin 1 |
| Class II aaRS ABD-related | 0.6775 | INHERITED FROM: Cidofovir |
| Glutathione synthetase ATP-binding domain-like | 0.6842 | INHERITED FROM: GW 4064 |
| Homeodomain-like | 0.6912 | INHERITED FROM: Panobinostat || Chir 98014 |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.7231 | INHERITED FROM: Vitamin E |
| SpoIIaa-like | 0.7231 | INHERITED FROM: Zidovudine || Thymidine |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.7476 | INHERITED FROM: Troglitazone || Albendazole || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || pyrithione zinc || Heterocyclic Compounds, 4 or More Rings || Thiazoles || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || Piperidines || Porphyrins || Tetrapyrroles || Chromans || Triazoles || usnic acid || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || Benzimidazoles || Quercetin || Pyrazoles || Indazoles |
| Orange domain-like | 0.7476 | INHERITED FROM: Thiazoles || Thiadiazoles || baicalein || Flavanones || baicalin || MRK 003 || Cyclic S-Oxides || Heterocyclic Oxides || Pyrazoles |
| E2F-DP heterodimerization region | 0.7726 | INHERITED FROM: Ochratoxins || Ritonavir || Nicotine || Solanaceous Alkaloids || Coumarins |
| LDL receptor-like module | 0.7882 | INHERITED FROM: Olanzapine |
| EF-hand | 0.7984 | INHERITED FROM: miglitol || Imino Pyranoses || entinostat || 1-Deoxynojirimycin || Pyridines || Aminopyridines |
| KRAB domain (Kruppel-associated box) | 0.813 | INHERITED FROM: Aflatoxin M1 || Leflunomide || Benzazepines || GSK-J4 || Isoxazoles |
| HLH, helix-loop-helix DNA-binding domain | 0.8495 | INHERITED FROM: Anthocyanins || 3-hydroxyflavone || propiconazole || Rifampin || 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-y || 2,3,4,7,8-pentachlorodibenzofuran || galangin || Thiazoles || Genistein || 2,3,7,8-tetrachlorodibenzofuran || baicalin || Cyclic S-Oxides || Indican || Heterocyclic Oxides |
| Polo-box domain | 0.8532 | INHERITED FROM: Troglitazone || Camptothecin || Genistein || Irinotecan |
| RING/U-box | 0.8715 | INHERITED FROM: PCI 32765 |
| Enolase N-terminal domain-like | 0.8816 | INHERITED FROM: Pterins || Pteridines || Aminopterin |
| Enolase C-terminal domain-like | 0.8816 | INHERITED FROM: Pterins || Pteridines || Aminopterin |
| L domain-like | 0.9038 | INHERITED FROM: Folfox protocol || NVP-TAE684 || Org 41841 || CMF regimen || 6-(methylamino)pyrido(3,4-d)pyrimidine |
| Kazal-type serine protease inhibitors | 0.9079 | INHERITED FROM: Nortropanes || trospium chloride || Rosuvastatin Calcium || naringin |
| Ankyrin repeat | 0.922 | INHERITED FROM: EKB 569 |
| Concanavalin A-like lectins/glucanases | 0.9492 | INHERITED FROM: Panobinostat |
| 4-helical cytokines | 0.9627 | INHERITED FROM: Cytochalasins || kaempferol || Azathioprine || StemRegenin 1 || bisindolylmaleimide I || Clozapine || Tropanes || Quinoxalines || Apomorphine || fisetin || Flavonolignans || 7-bromoindirubin-3'-oxime || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || tofacitinib || INCB018424 || Nitrofurans || gemcitabine || Histamine || Nicotinic Acids || Naphthyridines || 6-formylindolo(3,2-b)carbazole || E804 bisindole || Ro 41-5253 || Isoquinolines || Phloretin || Pteridines || Tyrphostins || SB 203580 || Pyrrolidines || Ergolines || Oxazines || brevetoxin 2 || Oxocins || Famotidine || 4-methylhistamine || FEC protocol || Terfenadine || Thiazoles || Polyphenols || Opiate Alkaloids || Maleimides || NVP ABE171 || Quinolines || Nevirapine || resiquimod || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Chlorpromazine || Isoindoles || Acids, Heterocyclic || Clonidine || Tetrazoles || Imidazoles || Dactinomycin || Phthalimides || beta-Lactams || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tetrapyrroles || Aripiprazole || Carbazoles || Flavones || Kaempferols || Isonicotinic Acids || Piperazines || Oxazoles || Adenine Nucleotides || 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one || Benzoxazoles || Ranitidine || 6,2',4'-trimethoxyflavone || Cocaine || Hesperidin || Benzimidazoles || epinastine || Ergot Alkaloids || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Morphinans || Calcimycin || Deoxycytidine || Azabicyclo Compounds || Patulin || Aporphines || rottlerin || Thymidine || FK 706 || hesperetin || SR 144528 || chrysin || Ciprofloxacin || montelukast |
| Spermadhesin, CUB domain | 0.9668 | INHERITED FROM: Panobinostat |
| TNF-like | 0.9668 | INHERITED FROM: Phenanthridines || Clozapine || sanguinarine || tofacitinib || candesartan || Pyridones || peroben || Atorvastatin || Paraquat || brevetoxin 2 || 3,5-bis(2-fluorobenzylidene)piperidin-4-one || Aripiprazole || Piperazines || Quinolones || Vemurafenib || Calcimycin || Benzophenanthridines || Y 27632 |
| Cystine-knot cytokines | 0.9694 | INHERITED FROM: Amiloride || Anthocyanins || N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide || Valsartan || fulvic acid || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Isoquinolines || Quinazolines || Uric Acid || SB 203580 || systhane || Heterocyclic Compounds, 4 or More Rings || Oxocins || Risperidone || Opiate Alkaloids || Protoporphyrins || Isoindoles || MOPP protocol || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || cyanidin || Phenytoin || Ramipril || Carbazoles || Adenine Nucleotides || Benzoxazoles || GSK1210151A || Morphinans || Calcimycin || delphinidin || Purine Nucleotides |
| Actin-like ATPase domain | 0.9819 | INHERITED FROM: Hemin || Albendazole || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || pyrithione zinc || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || Caffeine || yessotoxin || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || Benzimidazoles || indirubin-3'-monoxime || PP242 |
| alpha/beta-Hydrolases | 0.9968 | INHERITED FROM: 6-O-monoacetylmorphine || Physostigmine || Heroin || GW 4064 || Galantamine || 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime || Tacrine || RPR 121056 || Morphine Derivatives || Amaryllidaceae Alkaloids |
| BPTI-like | 1 | INHERITED FROM: Indolequinones || Mitomycins |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: Pipecuronium || broxaterol || Vortioxetine || Quinuclidinyl Benzilate || 7-hydroxymitragynine || proanthocyanidin || oxotremorine M || Oxotremorine || 7-fluoro-2-oxo-4-(2-(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)ethyl)-1,2-dihydroquinoline-1-aceta || 5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide || clobenpropit || BMY 7378 || abanoquil || Risperidone || Org 41841 || xylometazoline || (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) || 1,3-dipropyl-8-cyclopentylxanthine || N-methylhistamine || indole || 5-methylurapidil || Ketanserin || 7-methyl-6,7,8,9,14,15-hexahydro-5H-benz(d)indolo(2,3-g)azecine || CGP 20712A || 4-diphenylacetoxy-1,1-dimethylpiperidinium || Muscarine || Pilocarpine || brucine N-oxide || Dioxanes || Tropicamide || Oxymetazoline || Idazoxan || Lurasidone Hydrochloride || A 86929 || alfuzosin || 5-methylfurtrethonium || Tiotropium Bromide || quercitrin || N-Methylscopolamine |
| Trypsin-like serine proteases | 1 | INHERITED FROM: 4-Hydroxycoumarins || merbarone || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || aspalathin || Warfarin || nothofagin || Thiobarbiturates |
| C-type lectin-like | 1 | INHERITED FROM: Nebivolol |
| Insulin-like | 1 | INHERITED FROM: Dihydropyridines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Morpholines || Benzimidazoles |
| RNI-like | 1 | INHERITED FROM: 3,5-bis(2-fluorobenzylidene)piperidin-4-one |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| PapD-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| LysM domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| PRTase-like | 0 | Direct |
| Amine oxidase N-terminal region | 0 | Direct |
| R3H domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| PAZ domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| HIN-2000 domain-like | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| ISP domain | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| FF domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| SNF-like | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| GroES-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| ACP-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Connexin43 | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| BTG domain-like | 0 | Direct |
| Hermes dimerisation domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0 | Direct |
| Uteroglobin-like | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| ClpS-like | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| BolA-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Notch domain | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| MIR domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| PKD domain | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| FnI-like domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| GLA-domain | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Pseudouridine synthase | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Bromodomain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| TIMP-like | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| DNase I-like | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Metallothionein | 0 | Direct |
| SNARE-like | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Pentapeptide repeat-like | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| SIS domain | 0 | Direct |
| Triple coiled coil domain of C-type lectins | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| GFP-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| CCHHC domain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Anaphylotoxins (complement system) | 0 | Direct |
| BAG domain | 0 | Direct |
| Aldolase | 0 | Direct |
| Sema domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| ADC-like | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| Probable bacterial effector-binding domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| LEM domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| FKBP-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| WWE domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| Nop domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| GAF domain-like | 0 | Direct |
| PP2C-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| SRF-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| DNA clamp | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| STAT | 0 | Direct |
| LanC-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Release factor | 0 | Direct |
| LigT-like | 0 | Direct |
| RILP dimerisation region | 0 | Direct |
| YjeF N-terminal domain-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Phenylalanine zipper | 0 | Direct |
| GTF2I-like repeat | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Cytokine | 0 | Direct |
| Annexin | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| ITPase-like | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| FAS1 domain | 0 | Direct |
| GTPase activation domain, GAP | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| HIT-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| L30e-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| Tropomyosin | 0 | Direct |
| HRDC-like | 0 | Direct |
| UBC-like | 0 | Direct |
| N-(deoxy)ribosyltransferase-like | 0 | Direct |
| Hook domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Mss4-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| GYF domain | 0 | Direct |
| AlbA-like | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Integrin beta tail domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| SAND domain-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| NSFL1 (p97 ATPase) cofactor p47, SEP domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| DUSP-like | 0 | Direct |
| AXH domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| WW domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| MIT domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| PWI domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| DLC | 0 | Direct |
| Thiolase-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Cytochrome c oxidase subunit h | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| PEBP-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| eIF1-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| PUG domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Pentein | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| L27 domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Assembly domain of cartilage oligomeric matrix protein | 0 | Direct |
| RGC domain-like | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| HCP-like | 0 | Direct |
| Lipoxigenase | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| HAD-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Stathmin | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Trefoil | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| FAH | 0 | Direct |
| ARID-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| eIF4e-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| ACT-like | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| KA1-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Amine oxidase catalytic domain | 0 | Direct |
| TGS-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| AhpD-like | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Synuclein | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| PH domain-like | 0.000004951 | Direct |
| SH3-domain | 0.002875 | Inherited |
| Protein kinase-like (PK-like) | 0.003748 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.00543 | Inherited |
| FYVE/PHD zinc finger | 0.008159 | Inherited |
| EGF/Laminin | 0.01004 | Inherited |
| RNA-binding domain, RBD | 0.01203 | Inherited |
| SH2 domain | 0.01931 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.02064 | Inherited |
| Ubiquitin-like | 0.03174 | Inherited |
| ARM repeat | 0.04231 | Inherited |
| Cysteine proteinases | 0.0499 | Inherited |
| beta-beta-alpha zinc fingers | 0.05559 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.07484 | Inherited |
| Galactose-binding domain-like | 0.07793 | Inherited |
| Nucleic acid-binding proteins | 0.0808 | Inherited |
| E set domains | 0.1099 | Inherited |
| Growth factor receptor domain | 0.1544 | Inherited |
| FAD/NAD(P)-binding domain | 0.1611 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.1641 | Inherited |
| (Trans)glycosidases | 0.167 | Inherited |
| Mitochondrial carrier | 0.1729 | Inherited |
| Leucine zipper domain | 0.1791 | Inherited |
| SMAD/FHA domain | 0.1791 | Inherited |
| PX domain | 0.1857 | Inherited |
| Cadherin-like | 0.1978 | Inherited |
| Fibronectin type III | 0.1991 | Inherited |
| SET domain | 0.2216 | Inherited |
| Interleukin 8-like chemokines | 0.2372 | Inherited |
| p53-like transcription factors | 0.2456 | Inherited |
| PLP-dependent transferases | 0.2638 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.275 | Inherited |
| Periplasmic binding protein-like I | 0.2918 | Inherited |
| Thioredoxin-like | 0.2919 | Inherited |
| DBL homology domain (DH-domain) | 0.2948 | Inherited |
| MHC antigen-recognition domain | 0.3021 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.3094 | Inherited |
| vWA-like | 0.32 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3227 | Inherited |
| Fibrinogen C-terminal domain-like | 0.3581 | Inherited |
| Alkaline phosphatase-like | 0.3698 | Inherited |
| Ras GEF | 0.3824 | Inherited |
| Acetyl-CoA synthetase-like | 0.3824 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.4382 | Inherited |
| Kringle-like | 0.4382 | Inherited |
| HMG-box | 0.45 | Inherited |
| Voltage-gated potassium channels | 0.4513 | Inherited |
| HSP20-like chaperones | 0.4533 | Inherited |
| Class II aaRS and biotin synthetases | 0.4533 | Inherited |
| Myosin rod fragments | 0.4533 | Inherited |
| TNF receptor-like | 0.4686 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.4699 | Inherited |
| Hemopexin-like domain | 0.4829 | Inherited |
| Cystatin/monellin | 0.4829 | Inherited |
| Intermediate filament protein, coiled coil region | 0.4988 | Inherited |
| Immunoglobulin | 0.5128 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.528 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.528 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.528 | Inherited |
| Frizzled cysteine-rich domain | 0.5351 | Inherited |
| PGBD-like | 0.5537 | Inherited |
| MFS general substrate transporter | 0.5672 | Inherited |
| Cyclin-like | 0.578 | Inherited |
| DEATH domain | 0.5862 | Inherited |
| F-box domain | 0.5885 | Inherited |
| cAMP-binding domain-like | 0.6167 | Inherited |
| Histone-fold | 0.6224 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 0.6331 | Inherited |
| gamma-Crystallin-like | 0.6331 | Inherited |
| "Winged helix" DNA-binding domain | 0.6427 | Inherited |
| Serpins | 0.6431 | Inherited |
| Translation proteins SH3-like domain | 0.655 | Inherited |
| Snake toxin-like | 0.6569 | Inherited |
| Globin-like | 0.6775 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.6775 | Inherited |
| Class II aaRS ABD-related | 0.6775 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.6842 | Inherited |
| Homeodomain-like | 0.6912 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.7231 | Inherited |
| SpoIIaa-like | 0.7231 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.7476 | Inherited |
| Orange domain-like | 0.7476 | Inherited |
| E2F-DP heterodimerization region | 0.7726 | Inherited |
| LDL receptor-like module | 0.7882 | Inherited |
| EF-hand | 0.7984 | Inherited |
| KRAB domain (Kruppel-associated box) | 0.813 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.8495 | Inherited |
| Polo-box domain | 0.8532 | Inherited |
| RING/U-box | 0.8715 | Inherited |
| Enolase N-terminal domain-like | 0.8816 | Inherited |
| Enolase C-terminal domain-like | 0.8816 | Inherited |
| L domain-like | 0.9038 | Inherited |
| Kazal-type serine protease inhibitors | 0.9079 | Inherited |
| Ankyrin repeat | 0.922 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.9492 | Inherited |
| 4-helical cytokines | 0.9627 | Inherited |
| Spermadhesin, CUB domain | 0.9668 | Inherited |
| TNF-like | 0.9668 | Inherited |
| Cystine-knot cytokines | 0.9694 | Inherited |
| Actin-like ATPase domain | 0.9819 | Inherited |
| alpha/beta-Hydrolases | 0.9968 | Inherited |
| BPTI-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| RNI-like | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54928,57756
54928 - RNA-binding domain, RBD
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
47353,109640
47353 - Retrovirus capsid dimerization domain-like
109640 - KRAB domain (Kruppel-associated box) | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
50729,50729
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | DIRECT |
50729,46785
50729 - PH domain-like
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
57302,57302
57302 - Snake toxin-like
57302 - Snake toxin-like | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
103657,48350
103657 - BAR/IMD domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | DIRECT |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | DIRECT |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
46955,63763
46955 - Putative DNA-binding domain
63763 - SAND domain-like | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
50044,47769
50044 - SH3-domain
47769 - SAM/Pointed domain | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | DIRECT |
48670,48097
48670 - Transducin (heterotrimeric G protein), gamma chain
48097 - Regulator of G-protein signaling, RGS | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | DIRECT |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52087,48350
52087 - CRAL/TRIO domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
51905,47576
51905 - FAD/NAD(P)-binding domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
47576,143575
47576 - Calponin-homology domain, CH-domain
143575 - GAS2 domain-like | 0 | DIRECT |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | DIRECT |
49695,50370
49695 - gamma-Crystallin-like
50370 - Ricin B-like lectins | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
48371,49348
48371 - ARM repeat
49348 - Clathrin adaptor appendage domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
49410,50242
49410 - Alpha-macroglobulin receptor domain
50242 - TIMP-like | 0 | DIRECT |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | DIRECT |
54695,54695
54695 - POZ domain
54695 - POZ domain | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | DIRECT |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | DIRECT |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | DIRECT |
52540,50729
52540 - P-loop containing nucleoside triphosphate hydrolases
50729 - PH domain-like | 0 | DIRECT |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
54416,49998
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | DIRECT |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | DIRECT |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
54928,90209
54928 - RNA-binding domain, RBD
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | DIRECT |
56801,56801
56801 - Acetyl-CoA synthetase-like
56801 - Acetyl-CoA synthetase-like | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
54416,54416
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
90229,57850
90229 - CCCH zinc finger
57850 - RING/U-box | 0 | DIRECT |
64593,90257
64593 - Intermediate filament protein, coiled coil region
90257 - Myosin rod fragments | 0 | DIRECT |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
48726,49899
48726 - Immunoglobulin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
81901,81901
81901 - HCP-like
81901 - HCP-like | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
100895,48726
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | DIRECT |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
47113,-7
47113 - Histone-fold
-7 - CATH | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | DIRECT |
81296,101898
81296 - E set domains
101898 - NHL repeat | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | DIRECT |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
100895,50494
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57581,57581
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | DIRECT |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | DIRECT |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | DIRECT |
50249,46785
50249 - Nucleic acid-binding proteins
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | DIRECT |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47473,57610
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | DIRECT |
49265,49899
49265 - Fibronectin type III
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,56496
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
47576,140612
47576 - Calponin-homology domain, CH-domain
140612 - EB1 dimerisation domain-like | 0 | DIRECT |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | DIRECT |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | DIRECT |
56496,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
102848,54236
102848 - NSFL1 (p97 ATPase) cofactor p47, SEP domain
54236 - Ubiquitin-like | 0 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | DIRECT |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
52540,90002
52540 - P-loop containing nucleoside triphosphate hydrolases
90002 - Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
50729,57903
50729 - PH domain-like
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | DIRECT |
46579,64593
46579 - Prefoldin
64593 - Intermediate filament protein, coiled coil region | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
48403,47986
48403 - Ankyrin repeat
47986 - DEATH domain | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
57944,56436
57944 - Triple coiled coil domain of C-type lectins
56436 - C-type lectin-like | 0 | DIRECT |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | DIRECT |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,69179
53300 - vWA-like
69179 - Integrin domains | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
55186,55681
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
54277,50156
54277 - CAD & PB1 domains
50156 - PDZ domain-like | 0 | DIRECT |
50370,57440
50370 - Ricin B-like lectins
57440 - Kringle-like | 0 | DIRECT |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
49299,49299
49299 - PKD domain
49299 - PKD domain | 0 | DIRECT |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
81837,50978
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
48371,101447
48371 - ARM repeat
101447 - Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | DIRECT |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
82199,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
63763,57903
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
159141,159141
159141 - HIN-2000 domain-like
159141 - HIN-2000 domain-like | 0 | DIRECT |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | DIRECT |
57440,56436
57440 - Kringle-like
56436 - C-type lectin-like | 0 | DIRECT |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | DIRECT |
48452,48371
48452 - TPR-like
48371 - ARM repeat | 0 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | DIRECT |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
54909,54909
54909 - Dimeric alpha+beta barrel
54909 - Dimeric alpha+beta barrel | 0 | DIRECT |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
48452,81901
48452 - TPR-like
81901 - HCP-like | 0 | DIRECT |
57196,69687
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
90193,90193
90193 - Notch domain
90193 - Notch domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
48452,48403
48452 - TPR-like
48403 - Ankyrin repeat | 0 | DIRECT |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.04941 | INHERITED FROM: Quinoxalines || ML 7 || 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide || Panobinostat || Pyridines || Thiazoles || Imidazoles || Cyclic S-Oxides || GSK1210151A || Heterocyclic Oxides || napabucasin |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.1072 | INHERITED FROM: Aflatoxin M1 || Leflunomide || pomalidomide || Benzazepines || GSK-J4 || Isoxazoles |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.2128 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.2729 | INHERITED FROM: Naphthyridines || Benzodioxoles |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.37 | INHERITED FROM: Methapyrilene || aflatoxin B2 |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.3784 | INHERITED FROM: ponatinib || orantinib || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || Aripiprazole || (+)-JQ1 compound || aflatoxin B2 || Lenalidomide |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.3824 | INHERITED FROM: Thiazines || Vitamin E || entinostat || Penicillin G || Cephalosporins || Lactams || Quinazolines || Pyrrolidines || Fluoroquinolones || Gefitinib || Quinolines || Ampicillin || Lincosamides || Benzothiadiazines || Diltiazem || Imidazoles || beta-Lactams || valdecoxib || MRK 003 || Chlorothiazide || Cyclic S-Oxides || 2-Pyridinylmethylsulfinylbenzimidazoles || Ketorolac || Heterocyclic Oxides || Omeprazole |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0.4533 | INHERITED FROM: quinocetone || entinostat || Methapyrilene |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.4533 | INHERITED FROM: Benzylisoquinolines || 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone || Phenanthridines || cryptolepine || scriptaid || Tropanes || Silybin || Isoniazid || Atropine || Leflunomide || Flavonolignans || goniothalamin || Thiazines || Phenothiazines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Berberine || Nicotinic Acids || fludarabine || 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidin || Resveratrol || Indolizines || abemaciclib || Isoquinolines || Fluorouracil || pyrazolo(3,4-d)pyrimidine || Hypoxanthines || Quinazolines || Zidovudine || Benzothiazoles || Bridged Bicyclo Compounds, Heterocyclic || Oxazines || Aminoacridines || Guanine || Ethidium || Belladonna Alkaloids || Atropine Derivatives || Thiazoles || Morpholines || Ritonavir || Heterocyclic Compounds, Bridged-Ring || Zalcitabine || tylophorine || Acids, Heterocyclic || Celecoxib || Flavanones || ON123300 || N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea || Solanaceous Alkaloids || Lamivudine || Chromans || AC 93253 || Folic Acid || Flavones || palbociclib || Isonicotinic Acids || Piperazines || Oxazoles || usnic acid || Isoxazoles || Vemurafenib || Benzimidazoles || Chalcones || LG 100268 || 3,3'-diindolylmethane || Tocopherols || Acridines || Trabectedin || Lucanthone || alvocidib || Deoxycytidine || labedipinedilol A || 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one || Indazoles || CP-654577 || Thymidine || 1',2'-dihydrorotenone || Piroxicam |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.4993 | INHERITED FROM: ponatinib |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.528 | INHERITED FROM: Benzylisoquinolines || Tropanes || Atropine || Pentobarbital || Etomidate || 1-(4-methoxyphenyl)piperazine || Bicuculline || 4-chloro-N-(2-(2-thienyl)imidazo(1,2-a)pyridin-3-yl)benzamide || Pentylenetetrazole || tert-butylbicyclo-2-benzoate || Isoquinolines || 1-(2-methoxyphenyl)piperazine || Ro 15-4513 || epibatidine || Muscimol || Nicotine || Heterocyclic Compounds, Bridged-Ring || 1-(3-chlorophenyl)piperazine || desformylflustrabromine || Diterpene Alkaloids || Dimethylphenylpiperazinium Iodide || Quinolizines || methyllycaconitine || CL 218872 || Solanaceous Alkaloids || fipronil || L 663581 || gabazine || Piperazines || Bemegride || Benzodiazepines || loreclezole || Azocines || 1-(3-trifluoromethylphenyl)piperazine || 1-benzylpiperazine || Zolpidem || cisatracurium || Lobeline || tert-butylbicyclophosphorothionate || Tubocurarine || Mivacurium || Azabicyclo Compounds || Atracurium || phenylpiperazine || 1-(4-chlorophenyl)piperazine || bretazenil || Dihydro-beta-Erythroidine || cytisine || 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane || pozanicline |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.5537 | INHERITED FROM: Hydantoins || Benzylisoquinolines || 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || Silybin || Quinoxalines || Flavonolignans || RTKI cpd || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Amitrole || Isoflavones || deguelin || salinomycin || Picolinic Acids || 3-hydroxypicolinic acid || Aminoimidazole Carboxamide || Quinazolines || Pteridines || Tyrphostins || Aminopterin || SB 203580 || Pyrrolidines || manganese(III)-tetrakis(4-benzoic acid)porphyrin || CGS 27023A || Oxazines || AICA ribonucleotide || Morpholines || Thiadiazoles || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Nicotine || Dioxolanes || Porphyrins || Acids, Heterocyclic || Solanaceous Alkaloids || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tetrapyrroles || Xanthones || Phenytoin || Carbazoles || Triazoles || varespladib methyl || piperine || dieckol || BQ 788 || 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one || Dioxanes || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzodioxoles || Deoxycytidine || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || sauchinone || Y 27632 || 2-methyl-4-isothiazolin-3-one || chrysin || Ciprofloxacin |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.5729 | INHERITED FROM: 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || cobaltiprotoporphyrin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Picolinic Acids || 3-hydroxypicolinic acid || SB 203580 || manganese(III)-tetrakis(4-benzoic acid)porphyrin || CGS 27023A || Fluoroquinolones || Metalloporphyrins || Morpholines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || dieckol || Dioxanes || Ciprofloxacin |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.5922 | INHERITED FROM: Tunicamycin |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 0.655 | INHERITED FROM: Nicotinic Acids || Niflumic Acid |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0.655 | INHERITED FROM: Dihydropyridines || Nifedipine |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.6756 | INHERITED FROM: Lenalidomide |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.7231 | INHERITED FROM: Hydantoins || kaempferol || Bucladesine || Phenanthridines || Phenothiazines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid || Nicotinic Acids || Benzoxazines || Resveratrol || Lactams || Isoquinolines || Fluorouracil || Quinazolines || Pyrrolidines || Heterocyclic Compounds, 4 or More Rings || Paraquat || Oxazines || Thiazoles || Maleimides || Thiadiazoles || Piperidines || 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole || Chlorpromazine || Nicotine || Isoindoles || Porphyrins || Acids, Heterocyclic || baicalein || Dactinomycin || Flavanones || Solanaceous Alkaloids || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Pyrones || Pyrazines || Tetrapyrroles || Phenytoin || Apigenin || Carbazoles || Flavones || Kaempferols || Benzodiazepines || Benzimidazoles || Chalcones || Tocopherols || 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester || Benzophenanthridines || Y 27632 || Lactams, Macrocyclic || chrysin |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.7231 | INHERITED FROM: Vitamin E |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.7476 | INHERITED FROM: Thiazoles || Thiadiazoles || baicalein || Flavanones || baicalin || MRK 003 || Cyclic S-Oxides || Heterocyclic Oxides || Pyrazoles |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0.7726 | INHERITED FROM: senkirkine || Pyrrolizidine Alkaloids || Methimazole || Benzydamine || Indazoles |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.7726 | INHERITED FROM: Ochratoxins || Ritonavir || Nicotine || Solanaceous Alkaloids || Coumarins |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.8256 | INHERITED FROM: Tetrahydrofolates || Aminoquinolines || Quinoxalines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Uracil || Folfox protocol || Resveratrol || NVP-TAE684 || Pyridones || Fluorouracil || Cycloheximide || Quinazolines || Pteridines || Tyrphostins || Oxazines || Morpholines || Polyphenols || Quinolines || Piperidines || Imidazoles || CMF regimen || Formyltetrahydrofolates || Flavones || Rosiglitazone || Piperazines || 6-(methylamino)pyrido(3,4-d)pyrimidine || Lapatinib || Indazoles |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.8256 | INHERITED FROM: Tetrahydrofolates || Aminoquinolines || Quinoxalines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Uracil || Folfox protocol || Resveratrol || NVP-TAE684 || Pyridones || Fluorouracil || Cycloheximide || Quinazolines || Pteridines || Tyrphostins || Oxazines || Morpholines || Polyphenols || Quinolines || Piperidines || Imidazoles || CMF regimen || Formyltetrahydrofolates || Flavones || Rosiglitazone || Piperazines || 6-(methylamino)pyrido(3,4-d)pyrimidine || Lapatinib || Indazoles |
81383,49785
81383 - F-box domain
49785 - Galactose-binding domain-like | 0.8816 | INHERITED FROM: Bridged Bicyclo Compounds, Heterocyclic || Heterocyclic Compounds, Bridged-Ring || ICG 001 |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.9104 | INHERITED FROM: Leflunomide || Uracil || Fluorouracil || Camptothecin || Genistein || Isoxazoles || Irinotecan |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | INHERITED FROM: Hemin || Albendazole || N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine || pyrithione zinc || (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) || Caffeine || yessotoxin || 5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole || Benzimidazoles || indirubin-3'-monoxime || PP242 |
47986,52540
47986 - DEATH domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: Methapyrilene || Aminopyridines |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | INHERITED FROM: Rosiglitazone |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
54928,57756
54928 - RNA-binding domain, RBD
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
47353,109640
47353 - Retrovirus capsid dimerization domain-like
109640 - KRAB domain (Kruppel-associated box) | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
50729,50729
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | Direct |
50729,46785
50729 - PH domain-like
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
57302,57302
57302 - Snake toxin-like
57302 - Snake toxin-like | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
103657,48350
103657 - BAR/IMD domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | Direct |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | Direct |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
46955,63763
46955 - Putative DNA-binding domain
63763 - SAND domain-like | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
50044,47769
50044 - SH3-domain
47769 - SAM/Pointed domain | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | Direct |
48670,48097
48670 - Transducin (heterotrimeric G protein), gamma chain
48097 - Regulator of G-protein signaling, RGS | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | Direct |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52087,48350
52087 - CRAL/TRIO domain
48350 - GTPase activation domain, GAP | 0 | Direct |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
51905,47576
51905 - FAD/NAD(P)-binding domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
47576,143575
47576 - Calponin-homology domain, CH-domain
143575 - GAS2 domain-like | 0 | Direct |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | Direct |
49695,50370
49695 - gamma-Crystallin-like
50370 - Ricin B-like lectins | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
48371,49348
48371 - ARM repeat
49348 - Clathrin adaptor appendage domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
49410,50242
49410 - Alpha-macroglobulin receptor domain
50242 - TIMP-like | 0 | Direct |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | Direct |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | Direct |
54695,54695
54695 - POZ domain
54695 - POZ domain | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | Direct |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | Direct |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | Direct |
52540,50729
52540 - P-loop containing nucleoside triphosphate hydrolases
50729 - PH domain-like | 0 | Direct |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
54416,49998
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | Direct |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | Direct |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
54928,90209
54928 - RNA-binding domain, RBD
90209 - Ran binding protein zinc finger-like | 0 | Direct |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | Direct |
56801,56801
56801 - Acetyl-CoA synthetase-like
56801 - Acetyl-CoA synthetase-like | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
54416,54416
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
90229,57850
90229 - CCCH zinc finger
57850 - RING/U-box | 0 | Direct |
64593,90257
64593 - Intermediate filament protein, coiled coil region
90257 - Myosin rod fragments | 0 | Direct |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
48726,49899
48726 - Immunoglobulin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
81901,81901
81901 - HCP-like
81901 - HCP-like | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
100895,48726
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | Direct |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
47113,-7
47113 - Histone-fold
-7 - CATH | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | Direct |
81296,101898
81296 - E set domains
101898 - NHL repeat | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | Direct |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
100895,50494
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | Direct |
57581,57581
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | Direct |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | Direct |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | Direct |
50249,46785
50249 - Nucleic acid-binding proteins
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | Direct |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | Direct |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47473,57610
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | Direct |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | Direct |
49265,49899
49265 - Fibronectin type III
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,56496
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
47576,140612
47576 - Calponin-homology domain, CH-domain
140612 - EB1 dimerisation domain-like | 0 | Direct |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | Direct |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | Direct |
56496,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
102848,54236
102848 - NSFL1 (p97 ATPase) cofactor p47, SEP domain
54236 - Ubiquitin-like | 0 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | Direct |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
52540,90002
52540 - P-loop containing nucleoside triphosphate hydrolases
90002 - Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
50729,57903
50729 - PH domain-like
57903 - FYVE/PHD zinc finger | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | Direct |
46579,64593
46579 - Prefoldin
64593 - Intermediate filament protein, coiled coil region | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | Direct |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | Direct |
48403,47986
48403 - Ankyrin repeat
47986 - DEATH domain | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
57944,56436
57944 - Triple coiled coil domain of C-type lectins
56436 - C-type lectin-like | 0 | Direct |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | Direct |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,69179
53300 - vWA-like
69179 - Integrin domains | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
55186,55681
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
54277,50156
54277 - CAD & PB1 domains
50156 - PDZ domain-like | 0 | Direct |
50370,57440
50370 - Ricin B-like lectins
57440 - Kringle-like | 0 | Direct |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
49299,49299
49299 - PKD domain
49299 - PKD domain | 0 | Direct |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
81837,50978
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
48371,101447
48371 - ARM repeat
101447 - Formin homology 2 domain (FH2 domain) | 0 | Direct |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | Direct |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
82199,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
63763,57903
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger | 0 | Direct |
159141,159141
159141 - HIN-2000 domain-like
159141 - HIN-2000 domain-like | 0 | Direct |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | Direct |
57440,56436
57440 - Kringle-like
56436 - C-type lectin-like | 0 | Direct |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | Direct |
48452,48371
48452 - TPR-like
48371 - ARM repeat | 0 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | Direct |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
54909,54909
54909 - Dimeric alpha+beta barrel
54909 - Dimeric alpha+beta barrel | 0 | Direct |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
48452,81901
48452 - TPR-like
81901 - HCP-like | 0 | Direct |
57196,69687
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
90193,90193
90193 - Notch domain
90193 - Notch domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
48452,48403
48452 - TPR-like
48403 - Ankyrin repeat | 0 | Direct |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.04941 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.1072 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.2128 | Inherited |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.2729 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.37 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.3784 | Inherited |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.3824 | Inherited |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0.4533 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.4533 | Inherited |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.4993 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.528 | Inherited |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.5537 | Inherited |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.5729 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.5922 | Inherited |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 0.655 | Inherited |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0.655 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.6756 | Inherited |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.7231 | Inherited |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.7231 | Inherited |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.7476 | Inherited |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0.7726 | Inherited |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.7726 | Inherited |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.8256 | Inherited |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.8256 | Inherited |
81383,49785
81383 - F-box domain
49785 - Galactose-binding domain-like | 0.8816 | Inherited |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.9104 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | Inherited |
47986,52540
47986 - DEATH domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
100895,47473,57610
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
50370,57440,56436
50370 - Ricin B-like lectins
57440 - Kringle-like
56436 - C-type lectin-like | 0 | DIRECT |
57184,57581,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
50156,50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57184,100895,50494
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
81271,55186,55681
81271 - TGS-like
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
63763,57903,47370
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
48065,50729,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
57184,57581,57184
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
50156,50729,50729
50156 - PDZ domain-like
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
57440,56436,56436
57440 - Kringle-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
57184,100895,48726
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | DIRECT |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
48726,48726,49899
48726 - Immunoglobulin
48726 - Immunoglobulin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55186,55681,52954
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
75399,75399,75399
75399 - Plakin repeat
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,56496,49899
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57184,57184,57581
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
109640,57667,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
49899,57196,56496
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
49854,57535,49854
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
103473,103473,141571
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter
141571 - Pentapeptide repeat-like | 0 | DIRECT |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
49299,49299,49299
49299 - PKD domain
49299 - PKD domain
49299 - PKD domain | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
48403,48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
50729,81837,50978
50729 - PH domain-like
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | DIRECT |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
50044,55550,50044
50044 - SH3-domain
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
81901,48452,48452
81901 - HCP-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
50978,50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
50729,57863,48403
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
56487,56487,56487
56487 - SRCR-like
56487 - SRCR-like
56487 - SRCR-like | 0 | DIRECT |
100895,50494,50156
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | DIRECT |
57581,57184,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54416,54416,49998
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
49785,49899,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56496,49899,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.2283 | INHERITED FROM: trans-3,4'-dimethyl-3-hydroxyflavanone || Aflatoxins |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.2544 | INHERITED FROM: 1-Methyl-4-phenylpyridinium || Pyridines || Aflatoxin B1 || Cyclic S-Oxides || Heterocyclic Oxides || napabucasin |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.2548 | INHERITED FROM: Aflatoxin M1 || Leflunomide || Benzazepines || GSK-J4 || Isoxazoles |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6124 | INHERITED FROM: 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin || cobaltiprotoporphyrin || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Picolinic Acids || 3-hydroxypicolinic acid || SB 203580 || manganese(III)-tetrakis(4-benzoic acid)porphyrin || CGS 27023A || Fluoroquinolones || Metalloporphyrins || Morpholines || 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one || Tetrapyrroles || dieckol || Dioxanes || Ciprofloxacin |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.6131 | INHERITED FROM: ponatinib || orantinib || 5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one || PD 173074 || Lenalidomide |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.6331 | INHERITED FROM: Cytidine |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.6331 | INHERITED FROM: Tunicamycin |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.8256 | INHERITED FROM: Tetrahydrofolates || Aminoquinolines || Quinoxalines || 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one || Uracil || Folfox protocol || Resveratrol || NVP-TAE684 || Pyridones || Fluorouracil || Cycloheximide || Quinazolines || Pteridines || Tyrphostins || Oxazines || Morpholines || Polyphenols || Quinolines || Piperidines || Imidazoles || CMF regimen || Formyltetrahydrofolates || Flavones || Rosiglitazone || Piperazines || 6-(methylamino)pyrido(3,4-d)pyrimidine || Lapatinib || Indazoles |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
100895,47473,57610
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand
57610 - Thyroglobulin type-1 domain | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
50370,57440,56436
50370 - Ricin B-like lectins
57440 - Kringle-like
56436 - C-type lectin-like | 0 | Direct |
57184,57581,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57581 - TB module/8-cys domain | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
50156,50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57184,100895,50494
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases | 0 | Direct |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
81271,55186,55681
81271 - TGS-like
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
63763,57903,47370
63763 - SAND domain-like
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
48065,50729,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
57184,57581,57184
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
50156,50729,50729
50156 - PDZ domain-like
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
57440,56436,56436
57440 - Kringle-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
57184,100895,48726
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors
48726 - Immunoglobulin | 0 | Direct |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
48726,48726,49899
48726 - Immunoglobulin
48726 - Immunoglobulin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55186,55681,52954
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
75399,75399,75399
75399 - Plakin repeat
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,56496,49899
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57184,57184,57581
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
109640,57667,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
49899,57196,56496
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
49854,57535,49854
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
103473,103473,141571
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter
141571 - Pentapeptide repeat-like | 0 | Direct |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
49299,49299,49299
49299 - PKD domain
49299 - PKD domain
49299 - PKD domain | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
48403,48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
50729,81837,50978
50729 - PH domain-like
81837 - BEACH domain
50978 - WD40 repeat-like | 0 | Direct |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
50044,55550,50044
50044 - SH3-domain
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
81901,48452,48452
81901 - HCP-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
50978,50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
50729,57863,48403
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
56487,56487,56487
56487 - SRCR-like
56487 - SRCR-like
56487 - SRCR-like | 0 | Direct |
100895,50494,50156
100895 - Kazal-type serine protease inhibitors
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | Direct |
57581,57184,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54416,54416,49998
54416 - Amine oxidase N-terminal region
54416 - Amine oxidase N-terminal region
49998 - Amine oxidase catalytic domain | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
49785,49899,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56496,49899,49899
56496 - Fibrinogen C-terminal domain-like
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.2283 | Inherited |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.2544 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.2548 | Inherited |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6124 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.6131 | Inherited |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.6331 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.6331 | Inherited |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.8256 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Heterocyclic Compounds
