Domain combination pairs in Brachypodium distachyon

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1473 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	259	57
L domain-like	Protein kinase-like (PK-like)	244	40
P-loop containing nucleoside triphosphate hydrolases	L domain-like	184	26
F-box domain	RNI-like	147	16
RNA-binding domain, RBD	RNA-binding domain, RBD	115	21
L domain-like	L domain-like	114	46
L domain-like	RNI-like	96	39
Thioredoxin-like	GST C-terminal domain-like	85	6
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	83	6
Actin-like ATPase domain	Actin-like ATPase domain	82	18
RNI-like	Protein kinase-like (PK-like)	71	26
TPR-like	TPR-like	70	22
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	62	7
Barwin-like endoglucanases	PHL pollen allergen	61	3
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	59	6
ARM repeat	ARM repeat	58	29
Calcium ATPase, transduction domain A	HAD-like	54	11
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	53	10
ABC transporter transmembrane region	ABC transporter transmembrane region	53	6
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	53	8
HAD-like	Calcium ATPase, transmembrane domain M	53	10
Thiolase-like	Thiolase-like	52	2
TRAF domain-like	POZ domain	52	4
GroES-like	NAD(P)-binding Rossmann-fold domains	47	7
RING/U-box	ARM repeat	46	10
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	45	6
Cupredoxins	Cupredoxins	45	7
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	44	14
Protein kinase-like (PK-like)	EF-hand	44	3
Cyclin-like	Cyclin-like	42	7
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	40	8
P-loop containing nucleoside triphosphate hydrolases	RNI-like	38	19
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	37	9
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	37	6
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	37	8
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	36	3
Calcium ATPase, transmembrane domain M	Metal cation-transporting ATPase, ATP-binding domain N	36	3
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	36	3
Galactose-binding domain-like	(Trans)glycosidases	35	13
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	33	7
(Trans)glycosidases	Glycosyl hydrolase domain	32	10
RNI-like	RNI-like	32	20
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	32	12
DNA/RNA polymerases	Ribonuclease H-like	32	10
RING/U-box	RING/U-box	31	16
GroEL-intermediate domain like	GroEL apical domain-like	31	4
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	31	7
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	31	9
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	30	7
Trypsin-like serine proteases	PDZ domain-like	29	6
GroEL equatorial domain-like	GroEL-intermediate domain like	29	3
DNA-binding domain	DNA-binding domain	29	4
GroEL equatorial domain-like	GroEL apical domain-like	29	3
Voltage-gated potassium channels	cAMP-binding domain-like	28	5
F-box domain	Galactose oxidase, central domain	28	5
CCCH zinc finger	CCCH zinc finger	28	12
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	27	14
Homeodomain-like	Homeodomain-like	26	10
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	26	6
Protein kinase-like (PK-like)	ARM repeat	25	17
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	25	8
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	25	8
F-box domain	L domain-like	25	8
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	24	3
EGF/Laminin	Protein kinase-like (PK-like)	24	4
Retrovirus zinc finger-like domains	RNA-binding domain, RBD	24	6
Nucleic acid-binding proteins	Nucleic acid-binding proteins	23	17
Thioredoxin-like	Thioredoxin-like	23	13
Ubiquitin-like	Ubiquitin-like	23	8
ENTH/VHS domain	GAT-like domain	22	3
Retrovirus zinc finger-like domains	DNA/RNA polymerases	22	5
Growth factor receptor domain	Protein kinase-like (PK-like)	22	3
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	22	7
Retrovirus zinc finger-like domains	Ribonuclease H-like	21	5
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	21	4
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	21	3
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	21	4
GroES-like	GroES-like	21	5
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	20	1
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	20	10
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	20	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	20	5
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	20	10
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	19	2
PAZ domain	Ribonuclease H-like	19	4
DNA-binding pseudobarrel domain	CAD & PB1 domains	19	3
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	18	3
WRKY DNA-binding domain	WRKY DNA-binding domain	18	4
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	18	3
vWA-like	RING/U-box	18	5
Homeodomain-like	Bet v1-like	18	5
ACT-like	ACT-like	18	11
FYVE/PHD zinc finger	FYVE/PHD zinc finger	17	11
Periplasmic binding protein-like I	Periplasmic binding protein-like II	17	3
Galactose-binding domain-like	Galactose-binding domain-like	17	4
Phospholipase D/nuclease	Phospholipase D/nuclease	17	7
Single hybrid motif	CoA-dependent acyltransferases	17	5
Protein kinase-like (PK-like)	RING/U-box	17	6
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	17	4
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	17	5
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	17	4
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	17	2
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	16	5
WD40 repeat-like	WD40 repeat-like	16	8
Protein kinase-like (PK-like)	WD40 repeat-like	16	9
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	16	2
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	16	4
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	15	2
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	15	4
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	15	8
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	15	3
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	15	3
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	15	3
YhbY-like	YhbY-like	15	4
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	15	7
SNARE-like	SNARE fusion complex	15	2
CBS-domain pair	CBS-domain pair	14	6
Ubiquitin-like	UBA-like	14	8
Bet v1-like	Bet v1-like	14	5
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	14	2
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	14	3
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	14	6
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	14	4
PUA domain-like	SET domain	14	2
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	14	9
Ankyrin repeat	TPR-like	14	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	14	3
F-box domain	Kelch motif	14	3
Trypsin-like serine proteases	Trypsin-like serine proteases	14	8
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	14	3
Clc chloride channel	CBS-domain pair	14	2
EF-hand	EF-hand	14	5
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	14	1
E set domains	(Trans)glycosidases	14	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	14	7
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	13	4
Zinc hairpin stack	RING/U-box	13	5
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	13	3
Translation proteins	EF-G C-terminal domain-like	13	7
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	13	2
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	13	7
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	13	7
Subtilisin-like	PA domain	13	3
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	13	7
RNase III domain-like	dsRNA-binding domain-like	13	8
dsRNA-binding domain-like	dsRNA-binding domain-like	13	6
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	13	12
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	13	4
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	13	2
EF-hand	Riboflavin synthase domain-like	12	1
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	12	9
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	12	5
POZ domain	Skp1 dimerisation domain-like	12	3
ACT-like	Protein kinase-like (PK-like)	12	2
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	12	1
CHY zinc finger-like	Zinc hairpin stack	12	4
CHY zinc finger-like	RING/U-box	12	4
E set domains	Glycosyl hydrolase domain	12	4
Ankyrin repeat	RING/U-box	12	5
EF-G C-terminal domain-like	EF-G C-terminal domain-like	12	6
RING/U-box	TRAF domain-like	12	3
ARM repeat	Clathrin adaptor appendage domain	12	4
P-loop containing nucleoside triphosphate hydrolases	E set domains	12	3
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	12	4
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	12	3
Plant lectins/antimicrobial peptides	Plant lectins/antimicrobial peptides	11	6
vWA-like	beta-sandwich domain of Sec23/24	11	5
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	11	8
Zn-finger domain of Sec23/24	vWA-like	11	5
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	11	6
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	11	3
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	11	7
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	11	5
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	11	3
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	11	5
F-box domain	Tubby C-terminal domain-like	11	3
CAD & PB1 domains	Protein kinase-like (PK-like)	11	1
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	11	1
ARM repeat	WD40 repeat-like	11	7
beta-beta-alpha zinc fingers	Ribonuclease H-like	11	5
RNase III domain-like	RNase III domain-like	11	7
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	11	6
t-snare proteins	SNARE fusion complex	11	3
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	11	3
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	11	6
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	11	3
FYVE/PHD zinc finger	RING/U-box	11	8
RCC1/BLIP-II	FYVE/PHD zinc finger	11	3
PH domain-like	FYVE/PHD zinc finger	11	3
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	10	2
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	10	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	10	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	10	2
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	10	2
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	10	8
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	10	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	10	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	10	2
Adenine nucleotide alpha hydrolases-like	RING/U-box	10	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	10	2
RING/U-box	WD40 repeat-like	10	6
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	10	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	10	2
vWA-like	Helical domain of Sec23/24	10	4
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	10	4
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	10	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	10	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	10	4
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	10	2
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	10	7
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	10	2
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	10	2
E set domains	Ankyrin repeat	10	2
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	10	5
BRCT domain	BRCT domain	10	7
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	10	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	10	2
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	10	4
PH domain-like	RCC1/BLIP-II	9	2
Cullin repeat-like	Cullin homology domain	9	4
TPR-like	RING/U-box	9	5
FAS1 domain	FAS1 domain	9	3
MFS general substrate transporter	MFS general substrate transporter	9	2
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	9	5
CheY-like	Homeodomain-like	9	2
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	9	2
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	9	3
P-loop containing nucleoside triphosphate hydrolases	ARM repeat	9	5
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	9	5
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	9	5
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	9	3
FYVE/PHD zinc finger	Homeodomain-like	9	3
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	9	6
Saposin	Saposin	9	1
WD40 repeat-like	NHL repeat	9	1
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	9	1
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	9	3
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	9	3
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	9	6
Cullin homology domain	"Winged helix" DNA-binding domain	9	4
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	9	5
Ubiquitin-like	Zn-binding ribosomal proteins	9	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	9	4
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	9	1
RING/U-box	Nucleotide-diphospho-sugar transferases	9	2
NTF2-like	RNA-binding domain, RBD	9	2
PK beta-barrel domain-like	PK C-terminal domain-like	9	1
UBA-like	UBA-like	9	5
Chromo domain-like	Chromo domain-like	9	4
HCP-like	HCP-like	8	5
ADC-like	P-loop containing nucleoside triphosphate hydrolases	8	3
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	8	7
PAZ domain	RNase III domain-like	8	5
PH domain-like	Bet v1-like	8	3
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	8	4
ARM repeat	Hect, E3 ligase catalytic domain	8	2
ADC-like	Cdc48 domain 2-like	8	3
GroEL apical domain-like	SAICAR synthase-like	8	4
Translation proteins	Ribosomal protein S5 domain 2-like	8	5
Translational machinery components	L30e-like	8	2
Flavoproteins	Riboflavin synthase domain-like	8	4
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	8	5
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	8	2
Cullin repeat-like	"Winged helix" DNA-binding domain	8	3
TPR-like	Protein kinase-like (PK-like)	8	3
HMA, heavy metal-associated domain	HAD-like	8	7
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	8	4
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	8	4
TRAF domain-like	Cysteine proteinases	8	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	8	2
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	8	2
NAD(P)-binding Rossmann-fold domains	ACT-like	8	2
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	8	3
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	8	4
ARM repeat	Tudor/PWWP/MBT	8	5
PAZ domain	dsRNA-binding domain-like	8	5
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	8	2
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	8	5
GST C-terminal domain-like	eEF-1beta-like	8	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	8	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	8	5
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	7	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	7	6
Protease propeptides/inhibitors	Subtilisin-like	7	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	7	3
Thioredoxin-like	Ubiquitin-like	7	5
(Trans)glycosidases	Galactose mutarotase-like	7	4
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	7	4
SWIB/MDM2 domain	Plus3-like	7	5
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	7	2
PH domain-like	BEACH domain	7	4
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	7	5
FKBP-like	TPR-like	7	3
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	7	4
BEACH domain	WD40 repeat-like	7	4
FKBP-like	FKBP-like	7	3
UBA-like	XPC-binding domain	7	3
HD-domain/PDEase-like	Nucleotidyltransferase	7	3
Homodimeric domain of signal transducing histidine kinase	CheY-like	7	4
YrdC/RibB	RibA-like	7	2
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	7	2
L9 N-domain-like	Ribonuclease H-like	7	2
Actin depolymerizing proteins	Actin depolymerizing proteins	7	3
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	7	1
Initiation factor IF2/eIF5b, domain 3	Translation proteins	7	2
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	7	6
Sec7 domain	ARM repeat	7	6
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	7	1
FYVE/PHD zinc finger	SET domain	7	5
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	7	2
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	7	6
Acid proteases	Saposin	7	2
RING/U-box	Cysteine proteinases	7	5
Ubiquitin-like	XPC-binding domain	7	3
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	7	1
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	6	4
Zinc beta-ribbon	Cyclin-like	6	4
Plus3-like	GYF domain	6	4
SNARE fusion complex	SNARE fusion complex	6	1
FYVE/PHD zinc finger	Plus3-like	6	4
SWIB/MDM2 domain	GYF domain	6	4
Amine oxidase N-terminal region	Amine oxidase N-terminal region	6	2
PreATP-grasp domain	Rudiment single hybrid motif	6	5
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	6	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	6	3
RNA-binding domain, RBD	CCCH zinc finger	6	3
Actin depolymerizing proteins	VHP, Villin headpiece domain	6	2
Kelch motif	Kelch motif	6	5
Protein kinase-like (PK-like)	Ankyrin repeat	6	2
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	6	2
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	6	2
Plant lectins/antimicrobial peptides	Lysozyme-like	6	3
L domain-like	Adhesin YadA, collagen-binding domain	6	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	6	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	6	2
Carbamate kinase-like	ACT-like	6	2
F-box domain	F-box domain	6	3
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	6	4
WW domain	P-loop containing nucleoside triphosphate hydrolases	6	1
SAP domain	FYVE/PHD zinc finger	6	2
Ankyrin repeat	POZ domain	6	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	6	3
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	6	4
FYVE/PHD zinc finger	GYF domain	6	4
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	6	4
Amine oxidase N-terminal region	Amine oxidase catalytic domain	6	2
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	6	2
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	6	2
Voltage-gated potassium channels	Ankyrin repeat	6	2
WW domain	WW domain	6	4
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	6	1
Protein kinase-like (PK-like)	KA1-like	6	1
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	6	2
Voltage-gated potassium channels	Voltage-gated potassium channels	6	5
FYVE/PHD zinc finger	SWIB/MDM2 domain	6	4
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	6	2
(Trans)glycosidases	Ricin B-like lectins	6	2
Nucleic acid-binding proteins	Translation proteins SH3-like domain	6	4
TRAF domain-like	TRAF domain-like	6	2
ENT-like	Tudor/PWWP/MBT	6	2
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	6	2
cAMP-binding domain-like	Ankyrin repeat	6	2
NAD(P)-binding Rossmann-fold domains	Aldolase	6	2
Carbamate kinase-like	ALDH-like	6	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	6	2
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	6	1
PH domain-like	Oxysterol-binding protein-like	6	2
FF domain	FF domain	6	3
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	6	3
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	6	2
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	6	3
PH domain-like	WD40 repeat-like	6	3
Eukaryotic type KH-domain (KH-domain type I)	CCCH zinc finger	5	3
RCC1/BLIP-II	Protein kinase-like (PK-like)	5	3
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	5	2
PriA/YqbF domain	GINS helical bundle-like	5	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	5	3
PH domain-like	GTPase activation domain, GAP	5	1
Rudiment single hybrid motif	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	5	2
Galactose mutarotase-like	Glycosyl hydrolase domain	5	2
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	5	4
RING/U-box	BRCT domain	5	2
PH domain-like	ArfGap/RecO-like zinc finger	5	3
Ribonuclease H-like	HRDC-like	5	1
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	5	3
FAD/NAD(P)-binding domain	EF-hand	5	2
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	5	1
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	5	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	5	2
PA domain	Zn-dependent exopeptidases	5	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	5	3
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	5	1
TPR-like	Thioredoxin-like	5	3
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	5	2
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	5	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	5	3
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	5	1
P-loop containing nucleoside triphosphate hydrolases	Thioredoxin-like	5	2
Ran binding protein zinc finger-like	RNA-binding domain, RBD	5	3
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	5	2
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	5	2
PH domain-like	P-loop containing nucleoside triphosphate hydrolases	5	2
Ubiquitin-like	BAG domain	5	3
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	5	1
ARID-like	FYVE/PHD zinc finger	5	2
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	5	3
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	5	1
Sec63 N-terminal domain-like	E set domains	5	3
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	5	3
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	5	3
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	5	2
TAZ domain	RING/U-box	5	3
RNA-binding domain, RBD	PABC (PABP) domain	5	2
Protein kinase-like (PK-like)	PapD-like	5	2
PLC-like phosphodiesterases	PLC-like phosphodiesterases	5	2
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	5	2
PurM N-terminal domain-like	PurM C-terminal domain-like	5	4
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	5	2
ISP domain	Bet v1-like	5	2
Ricin B-like lectins	Ricin B-like lectins	5	2
PapD-like	WD40 repeat-like	5	2
CCCH zinc finger	RING/U-box	5	2
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	5	2
Periplasmic binding protein-like II	ACT-like	5	2
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	5	4
BAR/IMD domain-like	PH domain-like	5	3
alpha/beta-Hydrolases	alpha/beta-Hydrolases	5	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	5	1
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	5	2
Cytochrome f, large domain	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	5	2
Cytochrome f, large domain	Rudiment single hybrid motif	5	2
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	5	4
TPR-like	HCP-like	5	5
ARM repeat	Subdomain of clathrin and coatomer appendage domain	5	3
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	5	2
RuBisCO, large subunit, small (N-terminal) domain	RuBisCo, C-terminal domain	4	1
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	4	3
Ribonuclease H-like	Chromo domain-like	4	4
Tex N-terminal region-like	Ribonuclease H-like	4	2
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	4	1
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	4	1
PGBD-like	Metalloproteases ("zincins"), catalytic domain	4	2
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	4	2
TAZ domain	FYVE/PHD zinc finger	4	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	4	4
DUSP-like	Cysteine proteinases	4	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	4	2
PA domain	Transferrin receptor-like dimerisation domain	4	1
DNA-binding domain	DNA-binding pseudobarrel domain	4	3
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	4	4
Starch-binding domain-like	Galactose-binding domain-like	4	2
RING/U-box	Homeodomain-like	4	2
F-box domain	Clavaminate synthase-like	4	3
RuvA domain 2-like	SH2 domain	4	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	4	2
Serine metabolism enzymes domain	ACT-like	4	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	4	1
BAR/IMD domain-like	Ankyrin repeat	4	2
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	4	1
Ubiquitin-like	Cysteine proteinases	4	3
Amidase signature (AS) enzymes	TPR-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	4	3
POZ domain	TAZ domain	4	2
Nucleotidylyl transferase	Nucleotidylyl transferase	4	1
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
Tex N-terminal region-like	RuvA domain 2-like	4	2
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	4	2
UBC-like	RING/U-box	4	2
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	4	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	4	1
PH domain-like	Ankyrin repeat	4	2
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	4	2
ARM repeat	TPR-like	4	1
HAD-like	dsRNA-binding domain-like	4	2
SH2 domain	SH2 domain	4	2
L domain-like	Thioredoxin-like	4	1
PAH2 domain	PAH2 domain	4	1
Acid proteases	DNA/RNA polymerases	4	4
WD40 repeat-like	Cyclophilin-like	4	1
DNase I-like	DNA/RNA polymerases	4	2
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	4	3
Homeodomain-like	FAD/NAD(P)-binding domain	4	2
TPR-like	CAD & PB1 domains	4	2
Galactose oxidase, central domain	E set domains	4	2
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	4	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	4	2
Tex N-terminal region-like	SH2 domain	4	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	4	1
Ribosomal protein L6	Ribosomal protein L6	4	2
WW domain	FF domain	4	2
Plant invertase/pectin methylesterase inhibitor	Plant invertase/pectin methylesterase inhibitor	4	2
Ricin B-like lectins	Glycosyl hydrolase domain	4	1
Ribonuclease H-like	RuvA domain 2-like	4	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	4	4
ArfGap/RecO-like zinc finger	Ankyrin repeat	4	2
WD40 repeat-like	DPP6 N-terminal domain-like	4	2
PDZ domain-like	TPR-like	4	1
CAD & PB1 domains	RING/U-box	4	2
Cytochrome P450	Cytochrome P450	4	2
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	4	1
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	4	1
PA domain	RING/U-box	4	2
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	4	3
DNA clamp	DNA clamp	4	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	4	2
Metalloproteases ("zincins"), catalytic domain	HAD-like	4	1
Rhomboid-like	UBA-like	4	1
Kelch motif	Metallo-dependent phosphatases	4	1
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	3
SWIB/MDM2 domain	SWIB/MDM2 domain	4	2
PYP-like sensor domain (PAS domain)	GAF domain-like	4	3
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	4	3
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	4	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	4	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	4	2
P-loop containing nucleoside triphosphate hydrolases	TGS-like	4	3
Homeodomain-like	FAD-linked reductases, C-terminal domain	4	2
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	4	1
Ribonuclease H-like	SH2 domain	4	2
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	4	3
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	4
GAF domain-like	CheY-like	4	2
Rudiment single hybrid motif	Single hybrid motif	4	4
POZ domain	TPR-like	4	2
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	4	3
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	4	3
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	4	1
(Phosphotyrosine protein) phosphatases II	E set domains	4	2
Nucleotidylyl transferase	Ribosomal protein L25-like	4	2
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	4	4
E set domains	RNA-binding domain, RBD	4	1
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	4	2
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	4	2
ClpP/crotonase	ClpP/crotonase	4	4
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	4	1
Voltage-gated potassium channels	EF-hand	4	4
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	4	3
GAF domain-like	GAF domain-like	4	3
BAR/IMD domain-like	SH3-domain	4	1
Cysteine-rich domain	Cysteine-rich domain	4	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	4	3
RCC1/BLIP-II	RCC1/BLIP-II	4	3
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	4	3
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	4	1
Thioredoxin-like	FAD-dependent thiol oxidase	4	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	3
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	4	1
Ubiquitin-like	Homeodomain-like	4	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	4	2
CBS-domain pair	CAD & PB1 domains	4	2
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	3	3
beta-beta-alpha zinc fingers	P-loop containing nucleoside triphosphate hydrolases	3	2
Zinc beta-ribbon	Zinc beta-ribbon	3	1
E set domains	E set domains	3	3
Cysteine proteinases	Granulin repeat	3	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	3	3
Nucleic acid-binding proteins	GAD domain-like	3	2
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	3	2
Bowman-Birk inhibitor, BBI	Bowman-Birk inhibitor, BBI	3	2
RuvA domain 2-like	Nucleic acid-binding proteins	3	1
FYVE/PHD zinc finger	Chromo domain-like	3	2
Thioredoxin-like	Cysteine-rich domain	3	2
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
HAD-like	Riboflavin kinase-like	3	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	3	3
Thioredoxin-like	"Winged helix" DNA-binding domain	3	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
LDL receptor-like module	Mannose 6-phosphate receptor domain	3	1
PYP-like sensor domain (PAS domain)	F-box domain	3	1
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	3	1
Translation proteins	ThrRS/AlaRS common domain	3	2
DNase I-like	DNase I-like	3	1
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	3	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	3	1
Concanavalin A-like lectins/glucanases	PH domain-like	3	3
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	3	2
HAD-like	BRCT domain	3	1
F-box domain	HCP-like	3	2
WD40 repeat-like	DNase I-like	3	3
Ribonuclease H-like	Nucleic acid-binding proteins	3	1
P-loop containing nucleoside triphosphate hydrolases	Microbial and mitochondrial ADK, insert "zinc finger" domain	3	1
DNA-binding domain	YbaK/ProRS associated domain	3	2
Cyclophilin-like	RNA-binding domain, RBD	3	2
EF-hand	Mitochondrial carrier	3	1
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	3	2
RING/U-box	Ran binding protein zinc finger-like	3	1
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	3	2
Tex N-terminal region-like	Nucleic acid-binding proteins	3	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	3	2
TPR-like	SET domain	3	2
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	3	2
Protein kinase-like (PK-like)	NTF2-like	3	1
Dom34/Pelota N-terminal domain-like	L30e-like	3	1
Class II aaRS and biotin synthetases	GAD domain-like	3	2
YjeF N-terminal domain-like	FMN-binding split barrel	3	1
POZ domain	POZ domain	3	3
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	3	2
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	3	1
Ribonuclease H-like	Ribonuclease H-like	3	3
Tudor/PWWP/MBT	FYVE/PHD zinc finger	3	2
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	3	1
PUA domain-like	Nucleotidylyl transferase	3	1
LEA14-like	LEA14-like	3	2
Dom34/Pelota N-terminal domain-like	Translational machinery components	3	1
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	3	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	3	2
MoeA N-terminal region -like	MoeA C-terminal domain-like	3	1
UBA-like	PUG domain-like	3	2
PurS-like	PurM C-terminal domain-like	3	2
AraD/HMP-PK domain-like	HAD-like	3	1
HCP-like	HIT/MYND zinc finger-like	3	2
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	3	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	3	2
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	3	3
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	3	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	3	2
F-box domain	Quinoprotein alcohol dehydrogenase-like	3	1
E set domains	CBS-domain pair	3	2
HIT/MYND zinc finger-like	Cysteine proteinases	3	1
PDZ domain-like	ClpP/crotonase	3	2
PLP-dependent transferases	MOSC N-terminal domain-like	3	2
Nucleic acid-binding proteins	SH2 domain	3	1
Retrovirus zinc finger-like domains	RING/U-box	3	2
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	3	1
GST C-terminal domain-like	Nucleotidylyl transferase	3	1
Class II aaRS ABD-related	C-terminal domain of ProRS	3	2
E set domains	AMPKBI-like	3	1
TPR-like	Chaperone J-domain	3	3
WGR domain-like	ADP-ribosylation	3	3
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	3	2
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	3	2
PP2C-like	Protein kinase-like (PK-like)	3	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	3	3
PurS-like	PurM N-terminal domain-like	3	2
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	3	1
Clavaminate synthase-like	beta-beta-alpha zinc fingers	3	2
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	3	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	1
Tropomyosin	Apolipoprotein A-I	3	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	3	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	1
Homeodomain-like	"Winged helix" DNA-binding domain	3	1
RING/U-box	PUA domain-like	3	3
GST C-terminal domain-like	Ribosomal protein L25-like	3	1
PX domain	BAR/IMD domain-like	3	2
TPR-like	RNA-binding domain, RBD	3	2
Tudor/PWWP/MBT	SET domain	3	2
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	3	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	3	1
Mannose-binding lectins	Mannose-binding lectins	3	3
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	3	1
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	3	2
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	3	2
Oxidoreductase molybdopterin-binding domain	E set domains	3	2
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	3	1
Osmotin, thaumatin-like protein	Protein kinase-like (PK-like)	3	3
Glutamine synthetase/guanido kinase	GatB/YqeY motif	3	1
DNA/RNA polymerases	Chromo domain-like	3	3
ThrRS/AlaRS common domain	Class II aaRS ABD-related	3	2
Chaperone J-domain	4Fe-4S ferredoxins	3	1
RuvA domain 2-like	RuvA domain 2-like	3	1
Macro domain-like	CRAL/TRIO domain	3	1
Chaperone J-domain	Thioredoxin-like	3	2
F-box domain	TPR-like	3	1
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
Ankyrin repeat	Ankyrin repeat	3	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	3	2
"Winged helix" DNA-binding domain	E set domains	3	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	3	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	3	3
LysM domain	LysM domain	3	2
PreATP-grasp domain	Single hybrid motif	3	3
Serpins	Serpins	3	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	3	2
tRNA-binding arm	Class II aaRS and biotin synthetases	3	2
Acid proteases	Ribonuclease H-like	3	3
L9 N-domain-like	Ribosomal protein L9 C-domain	3	1
PurS-like	FGAM synthase PurL, linker domain	3	2
Clathrin heavy-chain terminal domain	ARM repeat	3	3
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	3	1
PUA domain-like	Ribosomal protein S5 domain 2-like	3	1
ARID-like	HSP20-like chaperones	3	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	3	1
TATA-box binding protein-like	TATA-box binding protein-like	3	2
RNA-binding domain, RBD	PWI domain	2	1
GST C-terminal domain-like	eEF1-gamma domain	2	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	2	1
Thioredoxin-like	NHL repeat	2	2
Concanavalin A-like lectins/glucanases	Nucleotide-diphospho-sugar transferases	2	1
Kelch motif	Tropomyosin	2	1
Staphylococcal nuclease	Tudor/PWWP/MBT	2	1
PRP4-like	Functional domain of the splicing factor Prp18	2	2
Calponin-homology domain, CH-domain	ARM repeat	2	1
Bromodomain	Bromodomain	2	1
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	2	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Histone-fold	Histone-fold	2	1
Chaperone J-domain	RNA-binding domain, RBD	2	1
FYVE/PHD zinc finger	TPR-like	2	1
F-box domain	ApaG-like	2	1
PurM N-terminal domain-like	PurM N-terminal domain-like	2	1
HAD-like	Thioredoxin-like	2	2
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	2	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	2	1
Cysteine proteinases	Cysteine proteinases	2	2
PH domain-like	HMG-box	2	1
PreATP-grasp domain	PreATP-grasp domain	2	2
Staphylococcal nuclease	Staphylococcal nuclease	2	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	2	2
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	2	2
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
UROD/MetE-like	UROD/MetE-like	2	1
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	1
PUA domain-like	SWIB/MDM2 domain	2	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	2	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	2	1
UBA-like	S-adenosyl-L-methionine-dependent methyltransferases	2	2
Trypsin-like serine proteases	Acyl-CoA N-acyltransferases (Nat)	2	1
Alpha-L RNA-binding motif	Pseudouridine synthase	2	2
Myosin rod fragments	ARM repeat	2	1
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	2	2
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	2
FYVE/PHD zinc finger	SAICAR synthase-like	2	2
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	2	1
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	2	1
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	2	1
Chaperone J-domain	Chaperone J-domain	2	2
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	2	1
Hermes dimerisation domain	Ribonuclease H-like	2	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	2	2
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	2	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	2	1
F-box domain	Outer arm dynein light chain 1	2	2
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	2	2
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	2	2
Ran binding protein zinc finger-like	Translation proteins	2	1
Pseudouridine synthase	PUA domain-like	2	1
Ubiquitin-like	Cap-Gly domain	2	2
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	2	2
POZ domain	Pentapeptide repeat-like	2	1
vWA-like	SPOC domain-like	2	2
Urease, gamma-subunit	Metallo-dependent hydrolases	2	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	2	2
Plus3-like	CCCH zinc finger	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	2	1
Nucleotide-diphospho-sugar transferases	ARM repeat	2	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	2	1
NAC domain	beta-beta-alpha zinc fingers	2	2
Cytidine deaminase-like	Dihydrofolate reductase-like	2	2
SWIB/MDM2 domain	CCCH zinc finger	2	2
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	2	1
SWIB/MDM2 domain	eIF1-like	2	1
HAD-like	NTF2-like	2	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	2
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	2	2
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Acid proteases	Chromo domain-like	2	2
PUG domain-like	Ubiquitin-like	2	2
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
Rhomboid-like	Ran binding protein zinc finger-like	2	2
GST C-terminal domain-like	Nucleic acid-binding proteins	2	1
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
NAC domain	NAC domain	2	2
RNA-binding domain, RBD	WW domain	2	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	1
Single hybrid motif	ClpP/crotonase	2	2
Rudiment single hybrid motif	ClpP/crotonase	2	2
LysM domain	Protein kinase-like (PK-like)	2	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	2	1
HD-domain/PDEase-like	ACT-like	2	1
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	2	1
Nucleotidylyl transferase	tRNA-binding arm	2	1
PapD-like	Ankyrin repeat	2	2
F-box domain	NTF2-like	2	2
F-box domain	WD40 repeat-like	2	2
Nucleoside hydrolase	Nucleoside hydrolase	2	2
RNA-binding domain, RBD	DPP6 N-terminal domain-like	2	2
NAD kinase/diacylglycerol kinase-like	NAD kinase/diacylglycerol kinase-like	2	2
Translation proteins	Translation proteins	2	1
BRCT domain	WGR domain-like	2	2
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	2	2
RNA-binding domain, RBD	ENTH/VHS domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	2	2
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	2	1
ARM repeat	PH domain-like	2	2
AN1-like Zinc finger	AN1-like Zinc finger	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	2	2
Nucleotidyltransferase	ACT-like	2	1
PH domain-like	Phospholipase D/nuclease	2	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	2	1
beta-sandwich domain of Sec23/24	P-loop containing nucleoside triphosphate hydrolases	2	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	2	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	2	1
Nucleotidyltransferase	TGS-like	2	1
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	2	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	2	1
TPR-like	HSP20-like chaperones	2	1
Chaperone J-domain	Sec63 N-terminal domain-like	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	2	2
Agglutinin	Aerolisin/ETX pore-forming domain	2	2
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	2	2
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	2	2
Translation proteins SH3-like domain	Translation proteins SH3-like domain	2	1
UBA-like	Hect, E3 ligase catalytic domain	2	1
HAD-like	NHL repeat	2	2
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	2	1
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	1
F-box domain	HIT/MYND zinc finger-like	2	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	2	1
SMAD/FHA domain	PP2C-like	2	2
BRCT domain	ADP-ribosylation	2	2
PRTase-like	PRTase-like	2	2
FYSH domain	Hypothetical protein AF0491, middle domain	2	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
UBC-like	Endosomal sorting complex assembly domain	2	1
F-box domain	SMI1/KNR4-like	2	1
RmlC-like cupins	RmlC-like cupins	2	1
ISP transmembrane anchor	ISP domain	2	1
TPR-like	PH domain-like	2	2
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	2	2
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	2	2
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
SNARE-like	Domain of the SRP/SRP receptor G-proteins	2	1
ARM repeat	POZ domain	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
Tropomyosin	Tropomyosin	2	1
Chaperone J-domain	ARM repeat	2	2
Ubiquitin-like	Hect, E3 ligase catalytic domain	2	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	1
PUA domain-like	eIF1-like	2	1
SAP domain	DNase I-like	2	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	2	1
E set domains	Riboflavin synthase domain-like	2	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	2	1
Starch-binding domain-like	Starch-binding domain-like	2	2
TPR-like	SMR domain-like	2	2
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	2	2
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
Urease, gamma-subunit	Urease, beta-subunit	2	2
Concanavalin A-like lectins/glucanases	WD40 repeat-like	2	2
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	2	2
Actin-crosslinking proteins	(Trans)glycosidases	2	1
Acetyl-CoA synthetase-like	ACP-like	2	2
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	2	1
FYVE/PHD zinc finger	GroEL apical domain-like	2	2
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Staphylococcal nuclease	2	2
Cyclophilin-like	TPR-like	2	1
Methylglyoxal synthase-like	Cytidine deaminase-like	2	2
Galactose-binding domain-like	Galactose mutarotase-like	2	2
PRTase-like	Ribulose-phoshate binding barrel	2	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
POZ domain	RNI-like	2	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	2	1
Taf5 N-terminal domain-like	WD40 repeat-like	2	1
PX domain	EreA/ChaN-like	2	1
PreATP-grasp domain	ClpP/crotonase	2	2
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	2	2
Arp2/3 complex subunits	Arp2/3 complex subunits	2	2
Starch-binding domain-like	Phosphoglycerate mutase-like	2	2
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	2	2
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	2	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	2	2
Cysteine proteinases	PF0523-like	2	2
FYVE/PHD zinc finger	CCCH zinc finger	2	2
Agglutinin	Agglutinin	2	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	2	2
RING/U-box	Cyclophilin-like	2	2
PRP4-like	WD40 repeat-like	2	1
Surp module (SWAP domain)	ENTH/VHS domain	2	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	2	2
Surp module (SWAP domain)	Surp module (SWAP domain)	2	2
GYF domain	CCCH zinc finger	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
E set domains	Cytochrome b5-like heme/steroid binding domain	2	1
Chaperone J-domain	beta-beta-alpha zinc fingers	2	1
UraD-Like	Transthyretin (synonym: prealbumin)	2	2
Urease, beta-subunit	Metallo-dependent hydrolases	2	2
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	2	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	2	2
SBT domain	Ankyrin repeat	2	1
F-box domain	Calcium-dependent phosphotriesterase	2	1
HIT/MYND zinc finger-like	Creatinase/aminopeptidase	2	1
SMI1/KNR4-like	ApaG-like	2	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	2	2
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	2	2
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	2	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	2	2
RING/U-box	UBA-like	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	2	1
4Fe-4S ferredoxins	Metallo-hydrolase/oxidoreductase	2	1
PurM C-terminal domain-like	PurM C-terminal domain-like	2	1
Thioredoxin-like	eEF1-gamma domain	2	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	1
Cryptochrome/photolyase, N-terminal domain	alpha/beta-Hydrolases	2	1
TPR-like	"Winged helix" DNA-binding domain	2	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	2	1
Macro domain-like	Zn-dependent exopeptidases	2	2
S-adenosyl-L-methionine-dependent methyltransferases	Formin homology 2 domain (FH2 domain)	2	2
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	2	2
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	2	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	2	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	2	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Class II aaRS and biotin synthetases	Translation proteins	2	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	2	2
Nucleic acid-binding proteins	eIF2alpha middle domain-like	2	1
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	2
TAZ domain	TAZ domain	2	1
L30e-like	alpha/beta knot	2	1
GroEL-intermediate domain like	SAICAR synthase-like	2	1
Chaperone J-domain	E set domains	2	1
GYF domain	SET domain	2	2
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	2	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	2	1
PurS-like	Class I glutamine amidotransferase-like	2	1
Galactose-binding domain-like	NAD(P)-binding Rossmann-fold domains	2	1
Restriction endonuclease-like	RuvA domain 2-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	2	2
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	1
ARM repeat	UBA-like	2	1
Clavaminate synthase-like	RING/U-box	2	2
POZ domain	Quinoprotein alcohol dehydrogenase-like	2	1
TGS-like	ACT-like	2	1
BRCT domain	FYVE/PHD zinc finger	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	2	2
RNI-like	Outer arm dynein light chain 1	2	2
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	2	1
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
DNase I-like	EF-hand	2	1
HD-domain/PDEase-like	TGS-like	2	1
RNA-binding domain, RBD	Surp module (SWAP domain)	2	1
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	1
Aconitase iron-sulfur domain	LeuD/IlvD-like	2	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
Putative isomerase YbhE	WD40 repeat-like	1	1
Nucleic acid-binding proteins	UBA-like	1	1
DNA-binding domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
Tricorn protease domain 2	ARM repeat	1	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Ribonuclease H-like	RNI-like	1	1
UBA-like	Thioredoxin-like	1	1
POZ domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
DNA/RNA polymerases	F-box domain	1	1
F-box domain	Tricorn protease domain 2	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Histone-fold	ARM repeat	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
L-aspartase-like	Class II aaRS ABD-related	1	1
Histone-fold	F-box domain	1	1
F-box domain	Putative isomerase YbhE	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
Acyl-CoA binding protein	Cysteine proteinases	1	1
BSD domain-like	BSD domain-like	1	1
Tropomyosin	Mitotic arrest deficient-like 1, Mad1	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	1	1
WD40 repeat-like	SNARE fusion complex	1	1
Aspartate/glutamate racemase	Aspartate/glutamate racemase	1	1
ARM repeat	Concanavalin A-like lectins/glucanases	1	1
ARID-like	RING/U-box	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
Cullin repeat-like	Homeodomain-like	1	1
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	1	1
EGF/Laminin	EGF/Laminin	1	1
beta-beta-alpha zinc fingers	RNI-like	1	1
CHY zinc finger-like	CHY zinc finger-like	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
DUSP-like	Ubiquitin-like	1	1
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	1	1
BRCT domain	PsbU/PolX domain-like	1	1
GYF domain	F-box domain	1	1
Protein kinase-like (PK-like)	Ribonuclease H-like	1	1
The spindle assembly checkpoint protein mad2	The spindle assembly checkpoint protein mad2	1	1
ARM repeat	alpha/beta knot	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
beta-beta-alpha zinc fingers	L domain-like	1	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	1	1
Second domain of FERM	P-loop containing nucleoside triphosphate hydrolases	1	1
UBC-like	Class II aaRS ABD-related	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
EF-hand	Calponin-homology domain, CH-domain	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	1	1
Tricorn protease domain 2	alpha/beta-Hydrolases	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
WD40 repeat-like	Bromodomain	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
Voltage-gated potassium channels	Formin homology 2 domain (FH2 domain)	1	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	1	1
SAP domain	ADP-ribosylation	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
alpha-helical ferredoxin	Nucleotide-binding domain	1	1
Second domain of FERM	Prismane protein-like	1	1
Homeodomain-like	L domain-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
Ubiquitin-like	L domain-like	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	1	1
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	1	1
Hypothetical protein PA1324	Cna protein B-type domain	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
RNI-like	Glutathione synthetase ATP-binding domain-like	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain I	1	1
POZ domain	WD40 repeat-like	1	1
DNA-binding domain	L domain-like	1	1
YgbK-like	Aldolase	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
alpha-helical ferredoxin	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
BRCT domain	DNA/RNA polymerases	1	1
Putative isomerase YbhE	RING/U-box	1	1
EF-hand	PLC-like phosphodiesterases	1	1
WD40 repeat-like	TPR-like	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
beta-sandwich domain of Sec23/24	WD40 repeat-like	1	1
Cysteine proteinases	Cytochrome P450	1	1
Ribosome inactivating proteins (RIP)	Cysteine proteinases	1	1
F-box domain	Tricorn protease N-terminal domain	1	1
GAF domain-like	CAD & PB1 domains	1	1
SAP domain	RNA-binding domain, RBD	1	1
EF-hand	RING/U-box	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
RNI-like	Ubiquitin-like	1	1
RNI-like	Mannose-binding lectins	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
HSP20-like chaperones	HSP20-like chaperones	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
RING/U-box	RNA-binding domain, RBD	1	1
Clathrin heavy-chain terminal domain	Protein kinase-like (PK-like)	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
F-box domain	(Phosphotyrosine protein) phosphatases II	1	1
Chaperone J-domain	CSL zinc finger	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
Second domain of FERM	PH domain-like	1	1
SSo0622-like	Kelch motif	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	1	1
ACP-like	Trimeric LpxA-like enzymes	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
SufE/NifU	BolA-like	1	1
F-box domain	Actin-like ATPase domain	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
Protein kinase-like (PK-like)	Thioredoxin-like	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
GroEL-intermediate domain like	GroEL-intermediate domain like	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	Aldolase	1	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	1	1
Tudor/PWWP/MBT	RNA-binding domain, RBD	1	1
RNI-like	ARM repeat	1	1
ARM repeat	SH3-domain	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
Ribonuclease H-like	F-box domain	1	1
Metalloproteases ("zincins"), catalytic domain	ARM repeat	1	1
ACP-like	Heme-dependent catalase-like	1	1
HIT-like	HIT-like	1	1
Ubiquitin-like	Protein kinase-like (PK-like)	1	1
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Carbamate kinase-like	DNA-binding pseudobarrel domain	1	1
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	Tropomyosin	1	1
(Trans)glycosidases	Chitinase insertion domain	1	1
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	1	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	1	1
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	1	1
"Winged helix" DNA-binding domain	Lumazine synthase	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
F-box domain	ARM repeat	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Cation efflux protein cytoplasmic domain-like	Cation efflux protein cytoplasmic domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	beta-sandwich domain of Sec23/24	1	1
ACT-like	Formyltransferase	1	1
PP2C-like	cAMP-binding domain-like	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
SMAD/FHA domain	BRCT domain	1	1
CAD & PB1 domains	UBA-like	1	1
Ribose/Galactose isomerase RpiB/AlsB	RmlC-like cupins	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
Enolase N-terminal domain-like	alpha/beta-Hydrolases	1	1
Cap-Gly domain	RNI-like	1	1
RING/U-box	Cytochrome P450	1	1
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
ACP-like	ACP-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
HMG-box	HMG-box	1	1
Outer arm dynein light chain 1	Protein kinase-like (PK-like)	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
CCCH zinc finger	HIT-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
Lysozyme-like	Lysozyme-like	1	1
alpha/beta-Hydrolases	Ribosomal protein S10	1	1
F-box domain	"Winged helix" DNA-binding domain	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Chelatase	Chlorophyll a-b binding protein	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	1	1
Class II aaRS and biotin synthetases	DNA-binding domain	1	1
RNI-like	WRKY DNA-binding domain	1	1
Translation proteins	PRC-barrel domain	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Epsilon subunit of F1F0-ATP synthase N-terminal domain	1	1
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
Galactose mutarotase-like	Starch-binding domain-like	1	1
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Voltage-gated potassium channels	Periplasmic binding protein-like II	1	1
Macro domain-like	Macro domain-like	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	1	1
F-box domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	1	1
F-box domain	YWTD domain	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
PRC-barrel domain	PRC-barrel domain	1	1
YjgF-like	YjgF-like	1	1
FKBP-like	Rhodanese/Cell cycle control phosphatase	1	1
Protein prenylyltransferase	Outer arm dynein light chain 1	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
DNA-glycosylase	DNA-glycosylase	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
DNA-glycosylase	Nudix	1	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
TPR-like	PUA domain-like	1	1
HAD-like	Protein kinase-like (PK-like)	1	1
PIN domain-like	Chromo domain-like	1	1
UBC-like	UBA-like	1	1
TGS-like	Class II aaRS ABD-related	1	1
2Fe-2S ferredoxin-like	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Pseudouridine synthase	Pseudouridine synthase	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
F-box domain	SET domain	1	1
Quinoprotein alcohol dehydrogenase-like	Soluble quinoprotein glucose dehydrogenase	1	1
Ubiquitin-like	Bromodomain	1	1
Chromo domain-like	Ankyrin repeat	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Group V grass pollen allergen	Group V grass pollen allergen	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
Plant invertase/pectin methylesterase inhibitor	NAC domain	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
TPR-like	Metallo-dependent phosphatases	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	1	1
Protein kinase-like (PK-like)	DPP6 N-terminal domain-like	1	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
Bacterial photosystem II reaction centre, L and M subunits	Photosystem II antenna protein-like	1	1
Hypothetical protein PA1324	Starch-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	1	1
DnaJ/Hsp40 cysteine-rich domain	DnaJ/Hsp40 cysteine-rich domain	1	1
R3H domain	Ankyrin repeat	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	1	1
P-loop containing nucleoside triphosphate hydrolases	POZ domain	1	1
SIS domain	Phosphoenolpyruvate/pyruvate domain	1	1
FMN-linked oxidoreductases	Nucleotide-binding domain	1	1
Tropomyosin	RING/U-box	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Bromodomain	Formin homology 2 domain (FH2 domain)	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
Cysteine proteinases	Nucleic acid-binding proteins	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Ribonuclease H-like	RING/U-box	1	1
F-box domain	Protein kinase-like (PK-like)	1	1
Acid proteases	Acid proteases	1	1
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	1	1
PFL-like glycyl radical enzymes	HCP-like	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
HCP-like	Homing endonucleases	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Sec1/munc18-like (SM) proteins	Sec1/munc18-like (SM) proteins	1	1
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
L domain-like	ARM repeat	1	1
PDZ domain-like	PDZ domain-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	1	1
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	1	1
ARID-like	Clavaminate synthase-like	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1
Trigger factor ribosome-binding domain	FKBP-like	1	1
F-box domain	LysM domain	1	1
SufE/NifU	NadA-like	1	1
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
P-loop containing nucleoside triphosphate hydrolases	HIT-like	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
FAD-linked oxidases, C-terminal domain	FAD-linked oxidases, C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
TPR-like	NAD kinase/diacylglycerol kinase-like	1	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
FAD-linked reductases, C-terminal domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Histone-fold	RNI-like	1	1
Flavoproteins	Radical SAM enzymes	1	1
P-loop containing nucleoside triphosphate hydrolases	GIY-YIG endonuclease	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
FAD/NAD(P)-binding domain	Nucleotide-binding domain	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
Lipocalins	Lipocalins	1	1
Putative isomerase YbhE	ARM repeat	1	1
Calcium-dependent phosphotriesterase	WD40 repeat-like	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
HAD-like	HAD-like	1	1
Ubiquitin-like	Acid proteases	1	1
Concanavalin A-like lectins/glucanases	Cysteine proteinases	1	1
L domain-like	PA domain	1	1
FKBP-like	Triger factor/SurA peptide-binding domain-like	1	1
Starch-binding domain-like	Nucleic acid-binding proteins	1	1
Cysteine proteinases	UBA-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
L-aspartase-like	Class II aaRS and biotin synthetases	1	1
SPOC domain-like	SAP domain	1	1
Acyl-CoA binding protein	Kelch motif	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
Acyl-CoA binding protein	PF0523-like	1	1
Macro domain-like	HIT-like	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Plant invertase/pectin methylesterase inhibitor	Ribonuclease H-like	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
FAD/NAD(P)-binding domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
Ankyrin repeat	RNA-binding domain, RBD	1	1
Actin-like ATPase domain	AF1104-like	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
ACP-like	Quinoprotein alcohol dehydrogenase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	TPR-like	1	1
Retrovirus zinc finger-like domains	Chromo domain-like	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
F-box domain	Cullin repeat-like	1	1
Starch-binding domain-like	Cna protein B-type domain	1	1
Chorismate mutase II	Chorismate mutase II	1	1
Mannose-binding lectins	alpha/beta-Hydrolases	1	1
ARM repeat	"Winged helix" DNA-binding domain	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	1	1
Galactose mutarotase-like	Galactose mutarotase-like	1	1
RNA-binding domain, RBD	SPOC domain-like	1	1
PDZ domain-like	Rubredoxin-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	1	1
Ankyrin repeat	CCCH zinc finger	1	1
Nucleic acid-binding proteins	S15/NS1 RNA-binding domain	1	1
PHL pollen allergen	PHL pollen allergen	1	1
vWA-like	Cysteine-rich domain	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
Translational machinery components	Insert subdomain of RNA polymerase alpha subunit	1	1
POZ domain	DPP6 N-terminal domain-like	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
RNI-like	(Phosphotyrosine protein) phosphatases II	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	1	1
Nucleotidyltransferase	EF-hand	1	1
alpha/beta-Hydrolases	Glycerol-3-phosphate (1)-acyltransferase	1	1
Cytidine deaminase-like	YbiA-like	1	1
GYF domain	RNA-binding domain, RBD	1	1
CheY-like	CheY-like	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
Dcp2 domain-like	Nudix	1	1
SBT domain	SBT domain	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
ARID-like	HMG-box	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
F-box domain	Cullin homology domain	1	1
Tricorn protease domain 2	DPP6 N-terminal domain-like	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
L domain-like	Subtilisin-like	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	1	1
CCCH zinc finger	WD40 repeat-like	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Ankyrin repeat	Kelch motif	1	1
POZ domain	Galactose-binding domain-like	1	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	1	1
Pre-PUA domain	PUA domain-like	1	1
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	1	1
L domain-like	FabD/lysophospholipase-like	1	1
Galactose-binding domain-like	Glycosyl hydrolase domain	1	1
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	1	1
BRCT domain	Nucleotidyltransferase	1	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
F-box domain	RING/U-box	1	1
Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	1	1
DUSP-like	DUSP-like	1	1
DNA/RNA polymerases	RNI-like	1	1
Chaperone J-domain	Homeodomain-like	1	1
Homeodomain-like	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Cysteine proteinases	Galactose-binding domain-like	1	1
DAK1/DegV-like	DhaL-like	1	1
Zn-binding ribosomal proteins	Zn-binding ribosomal proteins	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
Cullin repeat-like	Bet v1-like	1	1
PH domain-like	"Winged helix" DNA-binding domain	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
Galactose oxidase, central domain	Kelch motif	1	1
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
CarD-like	TRCF domain-like	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
HisI-like	all-alpha NTP pyrophosphatases	1	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
PLP-dependent transferases	PLP-dependent transferases	1	1
Cytidine deaminase-like	Cytidine deaminase-like	1	1
Barwin-like endoglucanases	Barwin-like endoglucanases	1	1
Ubiquitin-like	HAD-like	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Cysteine proteinases	DNA-binding domain	1	1
F-box domain	DNA-binding domain	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
EF-hand	TPR-like	1	1
Rhomboid-like	Rhomboid-like	1	1
Thioredoxin-like	VC0467-like	1	1
At5g01610-like	F-box domain	1	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
Formin homology 2 domain (FH2 domain)	EF-hand	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
Dihydrofolate reductase-like	YbiA-like	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
P-loop containing nucleoside triphosphate hydrolases	CCCH zinc finger	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
FAD/NAD(P)-binding domain	ACP-like	1	1
Cyclophilin-like	Retrovirus zinc finger-like domains	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	1	1
F-box domain	Pectin lyase-like	1	1
FAD/NAD(P)-binding domain	SMAD/FHA domain	1	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
cAMP-binding domain-like	cAMP-binding domain-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	RNA-binding domain, RBD	1	1
vWA-like	SAP domain	1	1
TPR-like	RNI-like	1	1
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
DNA repair protein MutS, domain I	GIY-YIG endonuclease	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
SET domain	HIT/MYND zinc finger-like	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
F-box domain	Soluble quinoprotein glucose dehydrogenase	1	1
Heme oxygenase-like	HAD-like	1	1
vWA-like	C-terminal domain of Ku80	1	1
"Winged helix" DNA-binding domain	Zinc beta-ribbon	1	1
Class I glutamine amidotransferase-like	ADC synthase	1	1
PYP-like sensor domain (PAS domain)	CheY-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PLP-dependent transferases	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
Acid proteases	UBA-like	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
SAP domain	WGR domain-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	1	1
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	1	1
SMAD/FHA domain	Phospholipase D/nuclease	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	1	1
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
Ubiquitin-like	F-box domain	1	1
PUA domain-like	alpha/beta knot	1	1
PH domain-like	Prismane protein-like	1	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	1	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
F-box domain	Peptidase/esterase 'gauge' domain	1	1
Protein kinase-like (PK-like)	PH domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	1	1
ARM repeat	BEACH domain	1	1
Chromo domain-like	Homeodomain-like	1	1
FtsH protease domain-like	FtsH protease domain-like	1	1
HD-domain/PDEase-like	EF-hand	1	1
Retrovirus zinc finger-like domains	Acid proteases	1	1