| Root: | SCOP hierarchy in SUPERFAMILY [ 0] (11) |
| Class: | Alpha and beta proteins (a/b) [ 51349] (141) |
| | Mainly parallel beta sheets (beta-alpha-beta units) |
| Fold: | P-loop containing nucleoside triphosphate hydrolases [ 52539] |
| | 3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes |
| Superfamily: | P-loop containing nucleoside triphosphate hydrolases [ 52540] (24) |
| Families: | Nucleotide and nucleoside kinases [ 52541] (20) |
| | parallel beta-sheet of 5 strands, order 23145 |
| | Shikimate kinase (AroK) [ 52566] |
| | similar to the nucleotide/nucleoside kinases but acts on different substrate |
| | Chloramphenicol phosphotransferase [ 52569] |
| | similar to the nucleotide/nucleoside kinases but acts on different substrate |
| | Gluconate kinase [ 75195] |
| | similar to the nucleotide/nucleoside kinases |
| | Plasmid maintenance system epsilon/zeta, toxin zeta subunit [ 82395] |
| | similar to the nucleotide/nucleoside kinases; extra N- and C-terminal structures |
| | Adenosine-5'phosphosulfate kinase (APS kinase) [ 52572] |
| | ATP sulfurylase C-terminal domain [ 64011] |
| | PAPS sulfotransferase [ 52575] (13) |
| | Pfam 00685
similar to the nucleotide/nucleoside kinases but transfer sulphate group |
| | Phosphoribulokinase/pantothenate kinase [ 52584] (5) |
| | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [ 52589] |
| | G proteins [ 52592] (78) |
| | core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest |
| | Motor proteins [ 52641] (4) |
| | Nitrogenase iron protein-like [ 52652] (13) |
| | core: parallel beta-sheet of 7 strands; order 3241567 |
| | RecA protein-like (ATPase-domain) [ 52670] (16) |
| | core: mixed beta-sheet of 8 strands, order 32451678; strand 7 is antiparallel to the rest |
| | Bacterial cell division inhibitor SulA [ 89678] |
| | homologous to RecA but lacks its P-loop motif; the fold is C-terminally truncated; 5-stranded parallel beta-sheet, order: 15423 |
| | ABC transporter ATPase domain-like [ 52686] (20) |
| | there are two additional subdomains inserted into the central core that has a RecA-like topology |
| | Tandem AAA-ATPase domain [ 81268] (22) |
| | duplication: tandem repeat of two RecA-like (AAA) domains |
| | Extended AAA-ATPase domain [ 81269] (27) |
| | fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain |
| | RNA helicase [ 52724] (3) |
| | duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension |
| | Helicase-like "domain" of reverse gyrase [ 69496] |
| | DNA helicase UvsW [ 102396] |
| | contains extra N-terminal alpha+beta subdomain |
| | YjeE-like [ 75213] |
| | mixed beta-sheet; order 234156(0), strands 2 and 6 are antiparallel to the rest |
| | Type II thymidine kinase [ 117558] |
| | N-terminal part of Pfam 00265; parallel beta-sheet of 6 strands, order 324516; topological similarity to the RecA-like proteins, especially CobA (scop_pr 52684) |
| | Atu3015-like [ 142332] (2) |
| | unknown function; similar to the nucleotide/nucleoside kinases |
The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level. Click on the 'Genome Assignments'
icon above to view the genome assignments for this superfamily.
It is possible to browse and view the proteins in the genomes which have
different combinations of domains including a P-loop containing nucleoside triphosphate hydrolases domain. Click on the 'Domain Combinations' icon.
To view the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom click on the 'TaxViz' icon above. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
Undirected domain occurrence networks are available for all superfamilies. Nodes in these networks represent genomes. Connections between nodes represent the presence of domain architectures, which contain the superfamily of interest, in both genomes.
There are 393 hidden Markov models representing the P-loop containing nucleoside triphosphate hydrolases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed by clicking on the icon above.
