Domain combination pairs in Loxodonta africana 76_3

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

2516 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	442	172
Immunoglobulin	Immunoglobulin	375	140
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	199	58
Fibronectin type III	Fibronectin type III	161	95
EGF/Laminin	EGF/Laminin	123	97
RNA-binding domain, RBD	RNA-binding domain, RBD	123	34
Immunoglobulin	Fibronectin type III	117	70
Cadherin-like	Cadherin-like	99	25
DBL homology domain (DH-domain)	PH domain-like	99	51
RING/U-box	B-box zinc-binding domain	99	19
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	82	31
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	82	27
RING/U-box	Concanavalin A-like lectins/glucanases	81	10
Intermediate filament protein, coiled coil region	Intermediate filament protein, coiled coil region	78	13
B-box zinc-binding domain	Concanavalin A-like lectins/glucanases	77	9
PH domain-like	PH domain-like	76	37
TPR-like	TPR-like	75	25
ARM repeat	ARM repeat	73	25
Second domain of FERM	PH domain-like	72	31
Actin-like ATPase domain	Actin-like ATPase domain	69	14
SH3-domain	SH3-domain	69	41
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	68	39
Ubiquitin-like	PH domain-like	67	29
HAD-like	Calcium ATPase, transmembrane domain M	67	12
Growth factor receptor domain	EGF/Laminin	66	60
PDZ domain-like	PDZ domain-like	66	38
PH domain-like	SH3-domain	61	30
Glucocorticoid receptor-like (DNA-binding domain)	Nuclear receptor ligand-binding domain	61	6
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	60	7
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	60	7
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	60	9
Calcium ATPase, transduction domain A	HAD-like	59	8
BAR/IMD domain-like	SH3-domain	59	14
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	58	4
MHC antigen-recognition domain	Immunoglobulin	57	4
POZ domain	Kelch motif	56	7
Voltage-gated potassium channels	Voltage-gated potassium channels	56	9
Complement control module/SCR domain	Complement control module/SCR domain	56	36
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	54	5
POZ domain	beta-beta-alpha zinc fingers	54	25
TSP-1 type 1 repeat	TSP-1 type 1 repeat	53	36
Homeodomain-like	Homeodomain-like	53	20
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	52	13
EF-hand	EF-hand	52	26
Ubiquitin-like	Second domain of FERM	51	20
Growth factor receptor domain	Growth factor receptor domain	50	39
KRAB domain (Kruppel-associated box)	beta-beta-alpha zinc fingers	49	29
Protein kinase-like (PK-like)	PH domain-like	49	27
L domain-like	L domain-like	49	26
EGF/Laminin	Concanavalin A-like lectins/glucanases	48	36
Immunoglobulin	Protein kinase-like (PK-like)	46	30
SH3-domain	SH2 domain	46	16
Spectrin repeat	Spectrin repeat	45	37
GTPase activation domain, GAP	PH domain-like	45	27
PH domain-like	SH2 domain	43	24
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	43	17
Sema domain	Plexin repeat	42	19
SH2 domain	Protein kinase-like (PK-like)	40	13
E set domains	E set domains	40	20
C2 domain (Calcium/lipid-binding domain, CaLB)	PH domain-like	40	22
Spermadhesin, CUB domain	Spermadhesin, CUB domain	40	28
Cysteine-rich domain	Protein kinase-like (PK-like)	40	22
FYVE/PHD zinc finger	FYVE/PHD zinc finger	39	20
SH3-domain	Protein kinase-like (PK-like)	39	13
Tudor/PWWP/MBT	Tudor/PWWP/MBT	38	19
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	38	17
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	37	3
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	37	12
L domain-like	Immunoglobulin	37	15
DBL homology domain (DH-domain)	SH3-domain	36	19
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	36	7
Fibronectin type III	Protein kinase-like (PK-like)	36	21
WW domain	WW domain	35	25
WD40 repeat-like	WD40 repeat-like	35	18
lambda repressor-like DNA-binding domains	Homeodomain-like	35	12
Cyclin-like	Cyclin-like	33	8
P-loop containing nucleoside triphosphate hydrolases	PDZ domain-like	31	16
Thioredoxin-like	GST C-terminal domain-like	31	5
FYVE/PHD zinc finger	Tudor/PWWP/MBT	31	11
Retrovirus capsid dimerization domain-like	beta-beta-alpha zinc fingers	31	19
(Phosphotyrosine protein) phosphatases II	PH domain-like	31	12
Protein kinase-like (PK-like)	ARM repeat	31	19
Concanavalin A-like lectins/glucanases	Fibronectin type III	31	17
PDZ domain-like	PH domain-like	31	20
Cysteine-rich domain	PH domain-like	30	18
Ankyrin repeat	Ankyrin repeat	30	25
LDL receptor-like module	LDL receptor-like module	29	27
Voltage-gated potassium channels	cAMP-binding domain-like	28	5
Protein kinase-like (PK-like)	SAM/Pointed domain	28	11
C-type lectin-like	C-type lectin-like	28	12
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	28	16
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	28	12
vWA-like	vWA-like	27	21
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	27	15
Myosin rod fragments	Myosin rod fragments	27	12
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	26	18
FYVE/PHD zinc finger	Clavaminate synthase-like	26	8
FYVE/PHD zinc finger	Bromodomain	26	15
SAM/Pointed domain	SAM/Pointed domain	24	11
Periplasmic binding protein-like I	Periplasmic binding protein-like II	24	7
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	24	1
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	24	8
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	24	12
Thioredoxin-like	Thioredoxin-like	24	9
PGBD-like	Metalloproteases ("zincins"), catalytic domain	24	6
Nucleotide-diphospho-sugar transferases	Ricin B-like lectins	24	2
Integrin domains	Integrin domains	24	8
PDZ domain-like	SH3-domain	23	10
Cysteine-rich domain	Cysteine-rich domain	23	12
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	23	4
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	23	4
RING/U-box	RING/U-box	23	13
POZ domain	Voltage-gated potassium channels	23	4
GroES-like	NAD(P)-binding Rossmann-fold domains	23	5
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	23	13
Protein kinase-like (PK-like)	KA1-like	23	3
BAR/IMD domain-like	GTPase activation domain, GAP	23	7
Metalloproteases ("zincins"), catalytic domain	Hemopexin-like domain	23	5
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	23	13
Integrin alpha N-terminal domain	Integrin domains	23	7
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	23	13
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	22	12
PH domain-like	EF-hand	22	11
ABC transporter transmembrane region	ABC transporter transmembrane region	22	4
Chromo domain-like	Chromo domain-like	21	6
Ubiquitin-like	Protein kinase-like (PK-like)	21	10
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	21	6
PGBD-like	Hemopexin-like domain	21	4
PH domain-like	ArfGap/RecO-like zinc finger	21	12
Growth factor receptor domain	Protein kinase-like (PK-like)	21	8
Calponin-homology domain, CH-domain	Spectrin repeat	21	16
GTPase activation domain, GAP	SH3-domain	20	9
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	20	7
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	20	13
F-box domain	RNI-like	20	5
Galactose-binding domain-like	Protein kinase-like (PK-like)	20	7
EF-hand	PLC-like phosphodiesterases	20	12
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	20	3
TNF receptor-like	TNF receptor-like	19	9
Growth factor receptor domain	Fibronectin type III	19	9
Bromodomain	Bromodomain	19	11
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	19	11
PH domain-like	Ankyrin repeat	19	10
L domain-like	Fibronectin type III	19	9
(Trans)glycosidases	Glycosyl hydrolase domain	19	9
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	18	10
Ankyrin repeat	SAM/Pointed domain	18	9
Sema domain	E set domains	18	10
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	18	3
L27 domain	PDZ domain-like	18	9
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	18	5
Integrin domains	vWA-like	18	8
Growth factor receptor domain	Concanavalin A-like lectins/glucanases	18	16
Ankyrin repeat	SOCS box-like	18	4
SRCR-like	SRCR-like	18	14
ARM repeat	Formin homology 2 domain (FH2 domain)	18	4
Sema domain	GTPase activation domain, GAP	17	8
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	17	5
Spectrin repeat	EF-hand	17	11
Galactose-binding domain-like	Growth factor receptor domain	17	8
Hormone receptor domain	Family A G protein-coupled receptor-like	17	5
BAR/IMD domain-like	PH domain-like	17	7
Voltage-gated potassium channels	E set domains	17	3
beta-beta-alpha zinc fingers	Homeodomain-like	17	12
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	17	8
Plexin repeat	E set domains	17	10
FnI-like domain	FnI-like domain	17	13
p53-like transcription factors	E set domains	17	4
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	17	9
Cadherin-like	Concanavalin A-like lectins/glucanases	16	9
TNF receptor-like	DEATH domain	16	6
Spermadhesin, CUB domain	Complement control module/SCR domain	16	10
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	16	6
EF-hand	RING/U-box	16	8
YWTD domain	EGF/Laminin	16	14
Snake toxin-like	Protein kinase-like (PK-like)	16	3
E set domains	GTPase activation domain, GAP	16	8
Concanavalin A-like lectins/glucanases	Immunoglobulin	16	7
Calponin-homology domain, CH-domain	EF-hand	16	7
Kringle-like	Kringle-like	16	11
Plexin repeat	GTPase activation domain, GAP	16	8
ArfGap/RecO-like zinc finger	Ankyrin repeat	16	8
UBA-like	Ubiquitin-like	16	10
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	16	5
Sec7 domain	PH domain-like	16	3
YWTD domain	LDL receptor-like module	15	14
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	15	9
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	15	12
PH domain-like	PLC-like phosphodiesterases	15	8
Protein kinase-like (PK-like)	PDZ domain-like	15	5
Galactose-binding domain-like	SAM/Pointed domain	15	6
Ubiquitin-like	Ras GEF	15	9
GroEL equatorial domain-like	GroEL apical domain-like	15	3
RNA-binding domain, RBD	NTF2-like	15	5
Glucocorticoid receptor-like (DNA-binding domain)	Homeodomain-like	15	4
PH domain-like	WD40 repeat-like	15	7
ARM repeat	PH domain-like	15	8
Fibronectin type III	SAM/Pointed domain	15	6
GroEL-intermediate domain like	GroEL apical domain-like	15	2
Ankyrin repeat	SH3-domain	15	7
dsRNA-binding domain-like	dsRNA-binding domain-like	15	11
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	15	5
RNA-binding domain, RBD	L domain-like	14	4
P-loop containing nucleoside triphosphate hydrolases	DEATH domain	14	9
Spermadhesin, CUB domain	EGF/Laminin	14	11
Actin depolymerizing proteins	Actin depolymerizing proteins	14	8
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	14	9
SAM/Pointed domain	"Winged helix" DNA-binding domain	14	6
L domain-like	Protein kinase-like (PK-like)	14	6
PDZ domain-like	Ubiquitin-like	14	10
EF-hand	SH3-domain	14	10
WW domain	Hect, E3 ligase catalytic domain	14	10
cAMP-binding domain-like	cAMP-binding domain-like	14	8
Nucleotide cyclase	Nucleotide cyclase	14	3
CCCH zinc finger	CCCH zinc finger	14	9
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	14	7
RING/U-box	Cysteine proteinases	14	7
FYVE/PHD zinc finger	SET domain	14	8
EGF/Laminin	Trypsin-like serine proteases	14	9
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	14	3
Cysteine-rich domain	C2 domain (Calcium/lipid-binding domain, CaLB)	13	10
vWA-like	EGF/Laminin	13	9
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	13	10
Nucleic acid-binding proteins	Nucleic acid-binding proteins	13	9
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	13	7
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	13	2
L domain-like	NTF2-like	13	3
EGF/Laminin	Complement control module/SCR domain	13	12
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	13	8
Cysteine proteinases	EF-hand	13	4
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	13	11
Galactose-binding domain-like	Fibronectin type III	13	5
UBA-like	RNA-binding domain, RBD	13	2
p53-like transcription factors	p53 tetramerization domain	13	2
Transglutaminase, two C-terminal domains	Transglutaminase, two C-terminal domains	13	2
L domain-like	Growth factor receptor domain	13	7
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	13	7
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	13	6
SH2 domain	SH2 domain	13	7
TSP-1 type 1 repeat	Growth factor receptor domain	13	8
BRCT domain	BRCT domain	13	9
Ubiquitin-like	Ubiquitin-like	13	10
P-loop containing nucleoside triphosphate hydrolases	RNI-like	13	6
Cysteine proteinases	Transglutaminase, two C-terminal domains	13	2
GroEL equatorial domain-like	GroEL-intermediate domain like	13	1
E set domains	Transglutaminase, two C-terminal domains	13	2
A DNA-binding domain in eukaryotic transcription factors	Leucine zipper domain	13	3
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	13	3
E set domains	Cysteine proteinases	13	2
C-type lectin-like	EGF/Laminin	13	12
WD40 repeat-like	ARM repeat	12	9
Retrovirus capsid dimerization domain-like	KRAB domain (Kruppel-associated box)	12	8
BEACH domain	WD40 repeat-like	12	8
NTF2-like	UBA-like	12	2
ENTH/VHS domain	GAT-like domain	12	3
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	12	6
PDZ domain-like	Glucocorticoid receptor-like (DNA-binding domain)	12	6
Immunoglobulin	C-type lectin-like	12	6
POZ domain	POZ domain	12	9
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	12	8
SMAD MH1 domain	SMAD/FHA domain	12	4
Cysteine-rich domain	GTPase activation domain, GAP	12	7
Serine protease inhibitors	Serine protease inhibitors	12	7
PH domain-like	Oxysterol-binding protein-like	12	4
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	12	6
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	12	6
Protein kinase-like (PK-like)	Ankyrin repeat	12	8
Ankyrin repeat	DEATH domain	12	8
Intermediate filament protein, coiled coil region	Prefoldin	12	5
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	12	4
L domain-like	Toll/Interleukin receptor TIR domain	12	7
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	12	1
EGF/Laminin	LDL receptor-like module	12	11
YWTD domain	Growth factor receptor domain	12	12
L27 domain	P-loop containing nucleoside triphosphate hydrolases	12	6
Growth factor receptor domain	SAM/Pointed domain	11	4
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	11	6
FYVE/PHD zinc finger	RING/U-box	11	6
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	11	3
RING/U-box	TRAF domain-like	11	9
Immunoglobulin	(Phosphotyrosine protein) phosphatases II	11	7
ARM repeat	Clathrin adaptor appendage domain	11	5
B-box zinc-binding domain	Fibronectin type III	11	4
E set domains	Terpenoid cyclases/Protein prenyltransferases	11	3
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	11	5
Phospholipase D/nuclease	Phospholipase D/nuclease	11	5
SRCR-like	Trypsin-like serine proteases	11	7
Calpain large subunit, middle domain (domain III)	EF-hand	11	2
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	11	3
vWA-like	Fibronectin type III	11	10
L domain-like	UBA-like	11	1
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	11	4
Second domain of FERM	Protein kinase-like (PK-like)	11	6
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	11	5
YWTD domain	YWTD domain	11	10
L27 domain	SH3-domain	11	5
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	11	7
Ubiquitin-like	Cysteine-rich domain	11	7
E set domains	Alpha-macroglobulin receptor domain	11	3
TSP-1 type 1 repeat	Immunoglobulin	10	6
Thiolase-like	Thiolase-like	10	4
L domain-like	Family A G protein-coupled receptor-like	10	5
Ribonuclease H-like	DNA/RNA polymerases	10	6
F-box domain	WD40 repeat-like	10	3
SAM/Pointed domain	PH domain-like	10	6
Transcription factor STAT-4 N-domain	SH2 domain	10	1
PX domain	BAR/IMD domain-like	10	3
Sema domain	Immunoglobulin	10	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	10	7
LDL receptor-like module	Spermadhesin, CUB domain	10	7
LDL receptor-like module	Trypsin-like serine proteases	10	7
Flavoproteins	Riboflavin synthase domain-like	10	7
MFS general substrate transporter	Kazal-type serine protease inhibitors	10	2
Transcription factor STAT-4 N-domain	STAT	10	1
Galactose-binding domain-like	(Trans)glycosidases	10	3
C-type lectin-like	Complement control module/SCR domain	10	9
Spectrin repeat	PH domain-like	10	9
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	10	7
Plexin repeat	vWA-like	10	6
ARM repeat	Concanavalin A-like lectins/glucanases	10	9
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	10	8
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	10	5
Clc chloride channel	CBS-domain pair	10	2
Plexin repeat	EGF/Laminin	10	6
POZ domain	Galactose oxidase, central domain	10	5
PYP-like sensor domain (PAS domain)	Voltage-gated potassium channels	10	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	10	4
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	10	6
Kelch motif	Kelch motif	10	3
Transcription factor STAT-4 N-domain	p53-like transcription factors	10	1
Plexin repeat	Immunoglobulin	10	3
Growth factor receptor domain	LDL receptor-like module	10	10
Kazal-type serine protease inhibitors	EF-hand	10	7
STAT	SH2 domain	10	1
Calponin-homology domain, CH-domain	PH domain-like	10	6
"Winged helix" DNA-binding domain	SMAD/FHA domain	10	2
HMG-box	HMG-box	10	5
Kringle-like	Trypsin-like serine proteases	10	10
Galactose-binding domain-like	Galactose-binding domain-like	10	8
Cadherin-like	EGF/Laminin	10	7
P-loop containing nucleoside triphosphate hydrolases	BRK domain-like	10	3
Protease propeptides/inhibitors	Zn-dependent exopeptidases	10	1
STAT	p53-like transcription factors	10	1
RING/U-box	Fibronectin type III	10	3
p53-like transcription factors	SH2 domain	10	1
Ubiquitin-like	ARM repeat	10	6
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	10	4
SET domain	beta-beta-alpha zinc fingers	10	7
Integrin domains	EGF/Laminin	9	5
EGF/Laminin	Galactose-binding domain-like	9	4
PX domain	SH3-domain	9	7
Spectrin repeat	Plakin repeat	9	9
SAM/Pointed domain	GTPase activation domain, GAP	9	4
GLA-domain	Trypsin-like serine proteases	9	5
Immunoglobulin	Toll/Interleukin receptor TIR domain	9	5
RNI-like	RNI-like	9	4
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	9	4
PH domain-like	BEACH domain	9	6
DEATH domain	DEATH domain	9	4
Cullin homology domain	"Winged helix" DNA-binding domain	9	3
Ubiquitin-like	GTPase activation domain, GAP	9	5
vWA-like	Integrin beta tail domain	9	5
Plexin repeat	Integrin beta tail domain	9	5
vWA-like	Integrin alpha N-terminal domain	9	3
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	9	1
EF-G C-terminal domain-like	EF-G C-terminal domain-like	9	5
PAZ domain	Ribonuclease H-like	9	3
WD40 repeat-like	RING/U-box	9	8
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	9	4
Subtilisin-like	Galactose-binding domain-like	9	6
Plexin repeat	Integrin domains	9	5
Galactose mutarotase-like	(Trans)glycosidases	9	5
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	9	3
Plakin repeat	Plakin repeat	9	9
DUSP-like	Cysteine proteinases	9	6
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	9	4
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	9	2
TB module/8-cys domain	TB module/8-cys domain	9	8
MAST3 pre-PK domain-like	PDZ domain-like	9	2
MAST3 pre-PK domain-like	Protein kinase-like (PK-like)	9	2
Regulator of G-protein signaling, RGS	PH domain-like	9	5
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	9	5
EGF/Laminin	Integrin beta tail domain	9	5
P-loop containing nucleoside triphosphate hydrolases	EF-hand	9	2
SH2 domain	SOCS box-like	9	3
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	9	8
ARID-like	Clavaminate synthase-like	9	5
DEATH domain	Protein kinase-like (PK-like)	9	6
BAR/IMD domain-like	Ankyrin repeat	9	4
TB module/8-cys domain	Growth factor receptor domain	9	8
PH domain-like	"Winged helix" DNA-binding domain	9	3
Galactose-binding domain-like	Concanavalin A-like lectins/glucanases	9	3
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	9	4
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	9	3
Kazal-type serine protease inhibitors	Kazal-type serine protease inhibitors	9	8
PX domain	Protein kinase-like (PK-like)	9	7
Ubiquitin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	9	5
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	9	3
DEATH domain	Caspase-like	9	4
PYP-like sensor domain (PAS domain)	cAMP-binding domain-like	9	2
EGF/Laminin	TB module/8-cys domain	9	8
Clavaminate synthase-like	Tudor/PWWP/MBT	8	2
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	8	6
TRAF domain-like	TRAF domain-like	8	7
Cullin repeat-like	Cullin homology domain	8	2
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	8	5
Immunoglobulin	DEATH domain	8	3
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	8	3
Periplasmic binding protein-like I	Voltage-gated potassium channels	8	2
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	8	5
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	8	5
vWA-like	Concanavalin A-like lectins/glucanases	8	7
CoA-dependent acyltransferases	CoA-dependent acyltransferases	8	1
Surp module (SWAP domain)	Surp module (SWAP domain)	8	3
Serum albumin-like	Serum albumin-like	8	3
Galactose mutarotase-like	Glycosyl hydrolase domain	8	4
Myosin rod fragments	Tropomyosin	8	3
Spermadhesin, CUB domain	Trypsin-like serine proteases	8	7
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	8	3
Translation proteins	EF-G C-terminal domain-like	8	4
PreATP-grasp domain	Rudiment single hybrid motif	8	6
Cupredoxins	Peptidylarginine deiminase Pad4, middle domain	8	1
GAF domain-like	HD-domain/PDEase-like	8	4
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	8	5
RING/U-box	UBA-like	8	5
Cupredoxins	Pentein	8	1
Tudor/PWWP/MBT	SAM/Pointed domain	8	5
SEA domain	Trypsin-like serine proteases	8	4
Integrin domains	Integrin beta tail domain	8	4
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	8	3
Ypt/Rab-GAP domain of gyp1p	EF-hand	8	1
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	8	2
PH domain-like	Ypt/Rab-GAP domain of gyp1p	8	5
Serine protease inhibitors	FnI-like domain	8	7
PH domain-like	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	8	1
Voltage-gated potassium channels	Small-conductance potassium channel	8	2
Ubiquitin-like	RING/U-box	8	4
ARID-like	FYVE/PHD zinc finger	8	4
Ubiquitin-like	Cysteine proteinases	8	6
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	8	2
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	8	5
vWA-like	Helical domain of Sec23/24	8	5
EF-hand	SH2 domain	8	5
SH3-domain	ARM repeat	8	2
C2 domain (Calcium/lipid-binding domain, CaLB)	SH2 domain	8	5
HLH, helix-loop-helix DNA-binding domain	Orange domain-like	8	2
PH domain-like	FYVE/PHD zinc finger	8	6
Cullin repeat-like	"Winged helix" DNA-binding domain	8	2
SH3-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	8	5
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	8	5
DBL homology domain (DH-domain)	PDZ domain-like	8	4
RNA-binding domain, RBD	Ran binding protein zinc finger-like	8	3
Peptidylarginine deiminase Pad4, middle domain	Pentein	8	1
Voltage-gated potassium channels	Periplasmic binding protein-like II	8	2
ClpP/crotonase	ClpP/crotonase	8	5
EF-hand	Cysteine-rich domain	8	2
GLA-domain	EGF/Laminin	8	4
beta-sandwich domain of Sec23/24	vWA-like	8	5
"Winged helix" DNA-binding domain	Ubiquitin-like	8	5
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	8	4
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	8	4
Bromodomain	Tudor/PWWP/MBT	8	3
Tudor/PWWP/MBT	SET domain	8	4
Growth factor receptor domain	Thyroglobulin type-1 domain	7	4
PDZ domain-like	"Winged helix" DNA-binding domain	7	4
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	7	2
ARM repeat	Subdomain of clathrin and coatomer appendage domain	7	2
SH3-domain	SAM/Pointed domain	7	4
Concanavalin A-like lectins/glucanases	TSP type-3 repeat	7	5
Nitric oxide (NO) synthase oxygenase domain	Riboflavin synthase domain-like	7	4
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	7	1
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	7	1
GST C-terminal domain-like	Nucleotidylyl transferase	7	4
Protease propeptides/inhibitors	Subtilisin-like	7	6
Protein kinase-like (PK-like)	NTF2-like	7	2
Calponin-homology domain, CH-domain	GAS2 domain-like	7	4
FF domain	FF domain	7	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	7	3
Plexin repeat	Plexin repeat	7	5
FnI-like domain	TSP-1 type 1 repeat	7	4
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	7	1
(Trans)glycosidases	(Trans)glycosidases	7	6
PreATP-grasp domain	Single hybrid motif	7	5
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	7	4
GAF domain-like	GAF domain-like	7	3
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	7	4
Cupredoxins	Cupredoxins	7	6
EF-hand	Mitochondrial carrier	7	3
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	7	5
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	7	3
Nitric oxide (NO) synthase oxygenase domain	Flavoproteins	7	4
Translation proteins	Ribosomal protein S5 domain 2-like	7	3
Complement control module/SCR domain	Trypsin-like serine proteases	7	5
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	7	4
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	7	1
LDL receptor-like module	SRCR-like	7	4
Sec7 domain	ARM repeat	7	3
TPR-like	ARM repeat	7	3
RNA-binding domain, RBD	ENTH/VHS domain	7	2
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	7	1
EF-hand	Thyroglobulin type-1 domain	7	5
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	7	1
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	7	1
WW domain	FF domain	7	4
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	7	1
Nucleotidyltransferase	Nucleotidyltransferase	7	5
Regulator of G-protein signaling, RGS	Ubiquitin-like	7	3
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	7	1
WD40 repeat-like	Bromodomain	7	4
Metalloproteases ("zincins"), catalytic domain	ARM repeat	7	2
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	7	2
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	7	7
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	7	1
alpha/beta-Hydrolases	Lipase/lipooxygenase domain (PLAT/LH2 domain)	7	1
Concanavalin A-like lectins/glucanases	Fibrinogen C-terminal domain-like	7	2
Spectrin repeat	SH3-domain	7	6
P-loop containing nucleoside triphosphate hydrolases	PUA domain-like	7	3
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	7	2
PAP/OAS1 substrate-binding domain	PAP/OAS1 substrate-binding domain	7	5
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	7	1
Second domain of FERM	PDZ domain-like	7	5
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	7	1
Rudiment single hybrid motif	Single hybrid motif	7	5
Nitric oxide (NO) synthase oxygenase domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	7	4
DBL homology domain (DH-domain)	GTPase activation domain, GAP	7	3
CRAL/TRIO domain	Spectrin repeat	7	6
CCCH zinc finger	RING/U-box	7	6
DEATH domain	RNI-like	7	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	7	3
Hedgehog/DD-peptidase	Hedgehog/intein (Hint) domain	7	1
DNase I-like	RNA-binding domain, RBD	7	1
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	7	1
Chromo domain-like	BRK domain-like	7	2
Growth factor receptor domain	FnI-like domain	7	5
Somatomedin B domain	Somatomedin B domain	7	5
MFS general substrate transporter	MFS general substrate transporter	7	3
TSP type-3 repeat	TSP type-3 repeat	7	5
lambda repressor-like DNA-binding domains	lambda repressor-like DNA-binding domains	7	5
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	7	6
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	7	5
BPTI-like	BPTI-like	7	7
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	7	1
GroES-like	GroES-like	7	1
Ankyrin repeat	POZ domain	7	6
Cap-Gly domain	Cap-Gly domain	7	5
EGF/Laminin	Fibrinogen C-terminal domain-like	7	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	7	1
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	7	3
FKBP-like	TPR-like	7	3
EGF/Laminin	TSP type-3 repeat	7	5
FnI-like domain	EGF/Laminin	7	4
Thioredoxin-like	Ubiquitin-like	7	3
Periplasmic binding protein-like I	Protein kinase-like (PK-like)	7	5
L domain-like	Calponin-homology domain, CH-domain	7	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	7	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	6	2
Periplasmic binding protein-like I	Nucleotide cyclase	6	4
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	6	1
TPR-like	Ankyrin repeat	6	5
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	6	3
Kazal-type serine protease inhibitors	Immunoglobulin	6	4
Fibronectin type III	Fibrinogen C-terminal domain-like	6	5
Ras GEF	PH domain-like	6	5
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	6	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	6	2
EGF/Laminin	Fibronectin type III	6	6
Calponin-homology domain, CH-domain	SH3-domain	6	2
PH domain-like	FAT domain of focal adhesion kinase	6	3
WW domain	GTPase activation domain, GAP	6	6
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	6	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	6	2
Second domain of FERM	FAT domain of focal adhesion kinase	6	3
PUA domain-like	RING/U-box	6	3
"Winged helix" DNA-binding domain	FYVE/PHD zinc finger	6	4
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	6	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	6	2
Immunoglobulin	EGF/Laminin	6	4
E set domains	Ankyrin repeat	6	2
C2 domain (Calcium/lipid-binding domain, CaLB)	C-terminal domain of PLC-beta	6	3
Ubiquitin-like	(Phosphotyrosine protein) phosphatases II	6	3
FYVE/PHD zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	6	4
CRAL/TRIO domain	DBL homology domain (DH-domain)	6	5
DBL homology domain (DH-domain)	WD40 repeat-like	6	1
Kazal-type serine protease inhibitors	EGF/Laminin	6	4
ARM repeat	Hect, E3 ligase catalytic domain	6	3
SAM/Pointed domain	Bet v1-like	6	2
SH3-domain	Fibronectin type III	6	4
(Phosphotyrosine protein) phosphatases II	SH2 domain	6	3
LDL receptor-like module	Concanavalin A-like lectins/glucanases	6	6
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	6	2
PA domain	RING/U-box	6	2
WW domain	PH domain-like	6	4
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	6	5
Doublecortin (DC)	Doublecortin (DC)	6	4
Protein kinase-like (PK-like)	Polo-box domain	6	4
SAND domain-like	Bromodomain	6	3
Kazal-type serine protease inhibitors	Thyroglobulin type-1 domain	6	4
Second domain of FERM	Moesin tail domain	6	2
t-snare proteins	SNARE fusion complex	6	2
SAND domain-like	FYVE/PHD zinc finger	6	3
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	6	4
GTPase activation domain, GAP	Bet v1-like	6	2
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	6	3
Zn-finger domain of Sec23/24	vWA-like	6	3
Carboxypeptidase regulatory domain-like	NHL repeat	6	4
Protein kinase-like (PK-like)	FAT domain of focal adhesion kinase	6	3
(Trans)glycosidases	Chitinase insertion domain	6	3
Ricin B-like lectins	Kringle-like	6	3
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	6	5
Frizzled cysteine-rich domain	TIMP-like	6	2
Spectrin repeat	DBL homology domain (DH-domain)	6	5
CAD & PB1 domains	Protein kinase-like (PK-like)	6	4
PA domain	Transferrin receptor-like dimerisation domain	6	1
Rap/Ran-GAP	PDZ domain-like	6	1
Calponin-homology domain, CH-domain	Glucocorticoid receptor-like (DNA-binding domain)	6	6
Concanavalin A-like lectins/glucanases	EF-hand	6	5
Ras GEF	EF-hand	6	3
Ubiquitin-like	FAT domain of focal adhesion kinase	6	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	6	3
IP3 receptor type 1 binding core, domain 2	EF-hand	6	5
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	6	5
Kringle-like	C-type lectin-like	6	3
PAH2 domain	PAH2 domain	6	3
PH domain-like	Moesin tail domain	6	2
Immunoglobulin	Complement control module/SCR domain	6	5
Galactose-binding domain-like	Fibrinogen C-terminal domain-like	6	1
EF-hand	DBL homology domain (DH-domain)	6	3
Protein kinase-like (PK-like)	Nucleotide cyclase	6	4
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	6	5
Concanavalin A-like lectins/glucanases	FnI-like domain	6	3
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	6	2
Lipovitellin-phosvitin complex, superhelical domain	Lipovitellin-phosvitin complex; beta-sheet shell regions	6	4
Putative DNA-binding domain	SAND domain-like	6	2
UBA-like	UBA-like	6	5
SH2 domain	GTPase activation domain, GAP	6	3
Cystatin/monellin	Cystatin/monellin	6	4
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	6	3
Cysteine proteinases	ARM repeat	6	4
RNA-binding domain, RBD	PABC (PABP) domain	6	2
B-box zinc-binding domain	FYVE/PHD zinc finger	6	5
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	6	3
Second domain of FERM	(Phosphotyrosine protein) phosphatases II	6	3
P-loop containing nucleoside triphosphate hydrolases	GTPase activation domain, GAP	6	4
IP3 receptor type 1 binding core, domain 2	Concanavalin A-like lectins/glucanases	6	5
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	6	3
Ribosomal protein L6	Ribosomal protein L6	6	1
EF-hand	C-terminal domain of PLC-beta	6	3
FYVE/PHD zinc finger	HMG-box	6	5
cAMP-binding domain-like	Ras GEF	6	4
Ricin B-like lectins	C-type lectin-like	6	3
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	6	2
SAM/Pointed domain	PDZ domain-like	6	5
PA domain	Zn-dependent exopeptidases	6	1
FYVE/PHD zinc finger	Chromo domain-like	6	2
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	6	4
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	6	5
PLC-like phosphodiesterases	C-terminal domain of PLC-beta	6	3
TSP-1 type 1 repeat	DEATH domain	6	2
Growth factor receptor domain	Kazal-type serine protease inhibitors	5	2
A heparin-binding domain	CAPPD, an extracellular domain of amyloid beta A4 protein	5	3
Subtilisin-like	Growth factor receptor domain	5	3
Clavaminate synthase-like	RNI-like	5	1
TPR-like	HCP-like	5	5
Anaphylotoxins (complement system)	TIMP-like	5	2
Protein kinase-like (PK-like)	G protein-binding domain	5	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	5	2
P-loop containing nucleoside triphosphate hydrolases	POZ domain	5	2
Terpenoid cyclases/Protein prenyltransferases	TIMP-like	5	2
Anaphylotoxins (complement system)	Alpha-macroglobulin receptor domain	5	2
F-box domain	Galactose-binding domain-like	5	2
TGS-like	ThrRS/AlaRS common domain	5	4
P-loop containing nucleoside triphosphate hydrolases	WW domain	5	5
RING/U-box	Ankyrin repeat	5	4
SH2 domain	VPS9 domain	5	5
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	5	2
gamma-Crystallin-like	gamma-Crystallin-like	5	2
N-terminal domain of cbl (N-cbl)	RING/U-box	5	3
C2 domain (Calcium/lipid-binding domain, CaLB)	FabD/lysophospholipase-like	5	2
Cysteine-rich domain	DBL homology domain (DH-domain)	5	4
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	5	3
TPR-like	RING/U-box	5	4
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	5	2
CalX-like	CalX-like	5	5
"Winged helix" DNA-binding domain	Ras GEF	5	3
RCC1/BLIP-II	RCC1/BLIP-II	5	4
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	5	4
P-loop containing nucleoside triphosphate hydrolases	TGS-like	5	1
MIR domain	IP3 receptor type 1 binding core, domain 2	5	4
RNase III domain-like	dsRNA-binding domain-like	5	3
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	5	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	5	4
ARM repeat	RING/U-box	5	4
RUN domain-like	Ypt/Rab-GAP domain of gyp1p	5	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	5	3
Metalloproteases ("zincins"), catalytic domain	EGF/Laminin	5	3
WW domain	EF-hand	5	3
G protein-binding domain	Cysteine-rich domain	5	3
SH2 domain	RING/U-box	5	3
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	5	2
PsbU/PolX domain-like	Nucleotidyltransferase	5	3
Hermes dimerisation domain	Ribonuclease H-like	5	4
Saposin	Saposin	5	3
Glucocorticoid receptor-like (DNA-binding domain)	VHP, Villin headpiece domain	5	3
FYVE/PHD zinc finger	RNI-like	5	1
Bromodomain	RING/U-box	5	2
WWE domain	Hect, E3 ligase catalytic domain	5	2
WWE domain	ADP-ribosylation	5	3
TPR-like	SH3-domain	5	3
Actin depolymerizing proteins	VHP, Villin headpiece domain	5	3
Outer arm dynein light chain 1	L domain-like	5	5
LDL receptor-like module	TSP-1 type 1 repeat	5	5
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	5	4
Concanavalin A-like lectins/glucanases	Family A G protein-coupled receptor-like	5	3
RNA-binding domain, RBD	Eukaryotic type KH-domain (KH-domain type I)	5	3
CCHHC domain	CCHHC domain	5	4
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	5	1
Calponin-homology domain, CH-domain	PRC-barrel domain	5	1
G protein-binding domain	PH domain-like	5	3
N-terminal domain of cbl (N-cbl)	SH2 domain	5	3
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	5	2
Ubiquitin-like	SH2 domain	5	4
RUN domain-like	FYVE/PHD zinc finger	5	3
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	5	3
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	5	3
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	5	3
beta-beta-alpha zinc fingers	Ribonuclease H-like	5	4
Cysteine-rich domain	SH3-domain	5	2
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	5	4
UBA-like	Cysteine proteinases	5	3
ARM repeat	WWE domain	5	2
Protease propeptides/inhibitors	Galactose-binding domain-like	5	4
HCP-like	HCP-like	5	5
Ras GEF	Cysteine-rich domain	5	2
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	5	5
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	5	3
Eukaryotic type KH-domain (KH-domain type I)	RING/U-box	5	2
Ribonuclease H-like	RNA-binding domain, RBD	5	5
PDZ domain-like	Regulator of G-protein signaling, RGS	5	3
SAP domain	RNA-binding domain, RBD	5	2
RNI-like	ARM repeat	5	1
vWA-like	Chicken cartilage matrix protein	5	4
Ubiquitin-like	Moesin tail domain	5	1
SMAD/FHA domain	PH domain-like	5	3
Alpha-macroglobulin receptor domain	TIMP-like	5	2
PHM/PNGase F	PHM/PNGase F	5	3
CRAL/TRIO domain	PH domain-like	5	4
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	5	2
beta-beta-alpha zinc fingers	Hermes dimerisation domain	5	4
Elafin-like	BPTI-like	5	5
Anaphylotoxins (complement system)	Terpenoid cyclases/Protein prenyltransferases	5	2
Calponin-homology domain, CH-domain	E set domains	5	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	5	2
N-terminal domain of cbl (N-cbl)	EF-hand	5	3
Spermadhesin, CUB domain	Concanavalin A-like lectins/glucanases	5	4
Concanavalin A-like lectins/glucanases	Metalloproteases ("zincins"), catalytic domain	5	5
PKD domain	PKD domain	5	4
HR1 repeat	HR1 repeat	5	2
Concanavalin A-like lectins/glucanases	WD40 repeat-like	5	4
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	5	3
gamma-Crystallin-like	Ricin B-like lectins	5	2
DBL homology domain (DH-domain)	BAR/IMD domain-like	5	3
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	5	2
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	5	1
Pectin lyase-like	Pectin lyase-like	5	4
cAMP-binding domain-like	Ubiquitin-like	5	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	5	5
HR1 repeat	Protein kinase-like (PK-like)	5	2
TAFH domain-like	Histone-fold	5	1
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	5	5
SH2 domain	Ras GEF	5	3
Regulator of G-protein signaling, RGS	PX domain	5	2
EGF/Laminin	TIMP-like	5	3
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	5	2
FAS1 domain	FAS1 domain	5	4
Thyroglobulin type-1 domain	Thyroglobulin type-1 domain	5	4
Second domain of FERM	SH2 domain	5	3
BRCT domain	Homeodomain-like	4	1
ArfGap/RecO-like zinc finger	GTPase activation domain, GAP	4	3
Calponin-homology domain, CH-domain	GTPase activation domain, GAP	4	3
ENTH/VHS domain	SH3-domain	4	1
EF-hand	NAD kinase/diacylglycerol kinase-like	4	1
PH domain-like	C-terminal domain of PLC-beta	4	2
Translation proteins SH3-like domain	Nucleic acid-binding proteins	4	2
UBA-like	ARM repeat	4	3
IP3 receptor type 1 binding core, domain 2	IP3 receptor type 1 binding core, domain 2	4	4
PH domain-like	I/LWEQ domain	4	2
PH domain-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	4	3
Second domain of FERM	alpha-catenin/vinculin-like	4	2
ENTH/VHS domain	Clathrin adaptor appendage domain	4	1
ARM repeat	BEACH domain	4	3
Spectrin repeat	RING/U-box	4	2
B-box zinc-binding domain	Bromodomain	4	3
BPTI-like	CAPPD, an extracellular domain of amyloid beta A4 protein	4	2
Galactose-binding domain-like	Carboxypeptidase regulatory domain-like	4	3
BRCT domain	DNA polymerase beta, N-terminal domain-like	4	2
Nucleotidylyl transferase	P-loop containing nucleoside triphosphate hydrolases	4	2
EF-hand	Dimeric alpha+beta barrel	4	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	4	1
L domain-like	EGF/Laminin	4	4
Amyloid beta a4 protein copper binding domain (domain 2)	BPTI-like	4	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	4	1
Polo-box domain	Polo-box domain	4	3
(Phosphotyrosine protein) phosphatases II	Chaperone J-domain	4	2
Carbonic anhydrase	Fibronectin type III	4	2
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	1
SAM/Pointed domain	ADP-ribosylation	4	3
Taf5 N-terminal domain-like	WD40 repeat-like	4	1
Phenylalanine zipper	SH2 domain	4	2
Somatomedin B domain	His-Me finger endonucleases	4	3
FAD/NAD(P)-binding domain	Glucocorticoid receptor-like (DNA-binding domain)	4	4
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
Nucleotidylyl transferase	Ribosomal protein L25-like	4	2
I/LWEQ domain	alpha-catenin/vinculin-like	4	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	4	2
Single hybrid motif	CoA-dependent acyltransferases	4	3
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	4	2
C2 domain (Calcium/lipid-binding domain, CaLB)	PX domain	4	3
Amyloid beta a4 protein copper binding domain (domain 2)	CAPPD, an extracellular domain of amyloid beta A4 protein	4	2
Single hybrid motif	ClpP/crotonase	4	3
Spectrin repeat	WW domain	4	2
Ligand-binding domain in the NO signalling and Golgi transport	Nucleotide cyclase	4	2
Guanido kinase N-terminal domain	Glutamine synthetase/guanido kinase	4	3
PH domain-like	alpha-catenin/vinculin-like	4	2
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	4	2
Trypsin-like serine proteases	Trypsin-like serine proteases	4	4
PH domain-like	Immunoglobulin	4	4
ARM repeat	PX domain	4	3
ARM repeat	Galactose-binding domain-like	4	3
GFP-like	EGF/Laminin	4	4
PreATP-grasp domain	ClpP/crotonase	4	3
ArfGap/RecO-like zinc finger	SH3-domain	4	1
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	4	2
Spermadhesin, CUB domain	C-type lectin-like	4	4
CRAL/TRIO domain	SH3-domain	4	3
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	4	1
Translation proteins	ThrRS/AlaRS common domain	4	3
RING/U-box	WWE domain	4	3
DBL homology domain (DH-domain)	SH2 domain	4	2
Zinc beta-ribbon	Cyclin-like	4	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	4	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Eferin C-derminal domain-like	4	2
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	4	2
Phenylalanine zipper	PH domain-like	4	2
ADC-like	Cdc48 domain 2-like	4	2
Ubiquitin-like	alpha-catenin/vinculin-like	4	2
Spermadhesin, CUB domain	SRCR-like	4	4
TPR-like	"Winged helix" DNA-binding domain	4	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	4	1
EGF/Laminin	Notch domain	4	3
Inhibitor of apoptosis (IAP) repeat	Inhibitor of apoptosis (IAP) repeat	4	3
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	4	2
SH2 domain	Cysteine-rich domain	4	2
FKBP-like	EF-hand	4	2
Growth factor receptor domain	Chicken cartilage matrix protein	4	3
GST C-terminal domain-like	S15/NS1 RNA-binding domain	4	2
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	4	3
P-loop containing nucleoside triphosphate hydrolases	FF domain	4	2
Tropomyosin	Tropomyosin	4	4
A middle domain of Talin 1	I/LWEQ domain	4	2
DBL homology domain (DH-domain)	Protein kinase-like (PK-like)	4	4
Cysteine-rich domain	SAM/Pointed domain	4	2
EF-hand	GAS2 domain-like	4	4
EGF/Laminin	Ankyrin repeat	4	3
Concanavalin A-like lectins/glucanases	PH domain-like	4	3
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	4	3
L27 domain	L27 domain	4	2
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	4	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Chaperone J-domain	4	2
TAFH domain-like	HIT/MYND zinc finger-like	4	1
PH domain-like	NAD kinase/diacylglycerol kinase-like	4	2
Notch domain	Ankyrin repeat	4	3
A middle domain of Talin 1	alpha-catenin/vinculin-like	4	2
Ankyrin repeat	Mib/herc2 domain-like	4	3
CCCH zinc finger	P-loop containing nucleoside triphosphate hydrolases	4	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	2
Rudiment single hybrid motif	ClpP/crotonase	4	3
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	4	3
PH domain-like	Tricorn protease domain 2	4	3
A heparin-binding domain	Amyloid beta a4 protein copper binding domain (domain 2)	4	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	4	3
TATA-box binding protein-like	TATA-box binding protein-like	4	2
L domain-like	Concanavalin A-like lectins/glucanases	4	4
vWA-like	Growth factor receptor domain	4	3
Actin-crosslinking proteins	Actin-crosslinking proteins	4	2
B-box zinc-binding domain	NHL repeat	4	3
Second domain of FERM	A middle domain of Talin 1	4	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	4	2
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	4	4
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	4	2
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	4	2
Ankyrin repeat	ADP-ribosylation	4	3
Tudor/PWWP/MBT	S-adenosyl-L-methionine-dependent methyltransferases	4	1
Concanavalin A-like lectins/glucanases	BEACH domain	4	3
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	4	2
Elafin-like	Elafin-like	4	3
RNase III domain-like	RNase III domain-like	4	2
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	4	2
Spermadhesin, CUB domain	Galactose-binding domain-like	4	3
Calponin-homology domain, CH-domain	RGC domain-like	4	3
NAD kinase/diacylglycerol kinase-like	SAM/Pointed domain	4	2
Regulator of G-protein signaling, RGS	DBL homology domain (DH-domain)	4	2
DBL homology domain (DH-domain)	Immunoglobulin	4	4
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	4	3
"Winged helix" DNA-binding domain	GTPase activation domain, GAP	4	1
GST C-terminal domain-like	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	4	3
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	4	2
SEA domain	SEA domain	4	3
Alkaline phosphatase-like	His-Me finger endonucleases	4	3
GAT-like domain	Clathrin adaptor appendage domain	4	1
Galactose-binding domain-like	RING/U-box	4	2
SH3-domain	Phosphoglycerate mutase-like	4	2
FAD/NAD(P)-binding domain	Calponin-homology domain, CH-domain	4	4
B-box zinc-binding domain	E set domains	4	3
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	4	3
SNARE fusion complex	SNARE fusion complex	4	2
TRAF domain-like	F-box domain	4	1
RNA-binding domain, RBD	SPOC domain-like	4	3
Somatomedin B domain	Alkaline phosphatase-like	4	3
Galactose-binding domain-like	Zn-dependent exopeptidases	4	3
Calponin-homology domain, CH-domain	Plakin repeat	4	4
Ubiquitin-like	I/LWEQ domain	4	2
Periplasmic binding protein-like II	Periplasmic binding protein-like II	4	2
ClpS-like	"Winged helix" DNA-binding domain	4	1
GFP-like	Growth factor receptor domain	4	4
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	4	3
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	4	2
GTF2I-like repeat	GTF2I-like repeat	4	3
P-loop containing nucleoside triphosphate hydrolases	TPR-like	4	2
A heparin-binding domain	BPTI-like	4	2
Second domain of FERM	I/LWEQ domain	4	2
PX domain	Ubiquitin-like	4	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	4	2
Ubiquitin-like	DBL homology domain (DH-domain)	4	3
ARID-like	Chromo domain-like	4	3
Notch domain	Notch domain	4	3
L domain-like	RNI-like	4	3
GTPase activation domain, GAP	RGC domain-like	4	3
WW domain	RING/U-box	4	2
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	2
Cysteine-rich DNA binding domain, (DM domain)	UBA-like	4	2
"Winged helix" DNA-binding domain	cAMP-binding domain-like	4	2
Formyltransferase	FMT C-terminal domain-like	4	3
Surp module (SWAP domain)	ENTH/VHS domain	4	2
Kelch motif	Galactose oxidase, central domain	4	3
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	4	1
Aconitase iron-sulfur domain	LeuD/IlvD-like	4	2
BAR/IMD domain-like	Cysteine-rich domain	4	2
SMAD/FHA domain	BRCT domain	4	2
MIR domain	MIR domain	4	4
DBL homology domain (DH-domain)	Ras GEF	4	4
BRCT domain	PsbU/PolX domain-like	4	2
Elongation factor TFIIS domain 2	Zinc beta-ribbon	4	2
RING/U-box	E set domains	4	2
Calponin-homology domain, CH-domain	WW domain	4	3
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	4	3
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	4	4
WW domain	PDZ domain-like	4	4
Growth factor receptor domain	Ankyrin repeat	4	3
BRCT domain	Nucleotidyltransferase	4	2
Cysteine-rich domain	Tricorn protease domain 2	4	3
Tricorn protease domain 2	WD40 repeat-like	4	4
Metalloproteases ("zincins"), catalytic domain	Spermadhesin, CUB domain	4	2
Growth factor receptor domain	Notch domain	4	3
PurM N-terminal domain-like	PurM C-terminal domain-like	4	3
FKBP-like	FKBP-like	4	2
Nucleotidyltransferase	Retrovirus zinc finger-like domains	4	3
Carbonic anhydrase	(Phosphotyrosine protein) phosphatases II	4	2
PH domain-like	A middle domain of Talin 1	4	2
PAP/OAS1 substrate-binding domain	Retrovirus zinc finger-like domains	4	3
I/LWEQ domain	I/LWEQ domain	4	2
Alkaline phosphatase-like	Alkaline phosphatase-like	4	2
Ubiquitin-like	A middle domain of Talin 1	4	2
EF-hand	Riboflavin synthase domain-like	3	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	3	1
Mib/herc2 domain-like	RING/U-box	3	2
HIN-2000 domain-like	HIN-2000 domain-like	3	3
Galactose-binding domain-like	Hect, E3 ligase catalytic domain	3	3
TGS-like	Class II aaRS and biotin synthetases	3	2
HMG-box	SET domain	3	3
Midkine	Midkine	3	2
Ubiquitin-like	SH3-domain	3	3
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	3	1
RUN domain-like	SH3-domain	3	2
Glycosyl hydrolase domain	Trefoil	3	3
Homeodomain-like	FAD/NAD(P)-binding domain	3	2
FYVE/PHD zinc finger	Elongation factor TFIIS domain 2	3	2
Heme-dependent peroxidases	Riboflavin synthase domain-like	3	1
Plexin repeat	TSP-1 type 1 repeat	3	3
Growth factor receptor domain	Mannose 6-phosphate receptor domain	3	1
Galactose mutarotase-like	Trefoil	3	3
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	3	2
NHL repeat	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	2
Triple coiled coil domain of C-type lectins	C-type lectin-like	3	1
WGR domain-like	ADP-ribosylation	3	3
Ubiquitin-like	PUA domain-like	3	1
Class II aaRS ABD-related	C-terminal domain of ProRS	3	1
Macro domain-like	ADP-ribosylation	3	2
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	3	1
TAZ domain	RING/U-box	3	1
Carboxypeptidase regulatory domain-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	2
Dimerization cofactor of HNF-1 alpha	Homeodomain-like	3	2
PX domain	PH domain-like	3	2
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	3	1
Prefoldin	WD40 repeat-like	3	2
PUA domain-like	Ribosomal protein S5 domain 2-like	3	1
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	3	2
Myosin S1 fragment, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	3	2
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	3	3
GST C-terminal domain-like	Class II aaRS ABD-related	3	1
Kix domain of CBP (creb binding protein)	Nuclear receptor coactivator interlocking domain	3	1
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	3	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	3	2
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	3	1
RING/U-box	Nuclear receptor coactivator interlocking domain	3	1
RCC1/BLIP-II	POZ domain	3	2
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	3	2
TAZ domain	TAZ domain	3	1
E set domains	NHL repeat	3	2
PX domain	Phospholipase D/nuclease	3	2
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	3	3
Cadherin-like	Growth factor receptor domain	3	3
SET domain	TPR-like	3	2
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	3	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	3	2
"Winged helix" DNA-binding domain	Acyl-CoA N-acyltransferases (Nat)	3	2
Restriction endonuclease-like	RuvA domain 2-like	3	3
S15/NS1 RNA-binding domain	C-terminal domain of ProRS	3	1
TSP-1 type 1 repeat	TSP type-3 repeat	3	1
CBS-domain pair	CBS-domain pair	3	2
MIR domain	Concanavalin A-like lectins/glucanases	3	2
Dimerization cofactor of HNF-1 alpha	lambda repressor-like DNA-binding domains	3	2
Eukaryotic type KH-domain (KH-domain type I)	P-loop containing nucleoside triphosphate hydrolases	3	2
RCC1/BLIP-II	Galactose-binding domain-like	3	2
DBL homology domain (DH-domain)	"Winged helix" DNA-binding domain	3	1
Sema domain	TSP-1 type 1 repeat	3	3
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	3	1
GST C-terminal domain-like	Ribosomal protein L25-like	3	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	3	2
Bet v1-like	HAD-like	3	2
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	3	1
TRAF domain-like	Trimerization domain of TRAF	3	2
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	3	2
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	3	1
LDL receptor-like module	Frizzled cysteine-rich domain	3	2
Growth factor receptor domain	Immunoglobulin	3	1
PH domain-like	Phospholipase D/nuclease	3	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	3	2
Concanavalin A-like lectins/glucanases	(Phosphotyrosine protein) phosphatases II	3	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	3	2
NAD kinase/diacylglycerol kinase-like	Ankyrin repeat	3	1
FYVE/PHD zinc finger	PUA domain-like	3	1
MIR domain	EF-hand	3	2
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	3	1
Initiation factor IF2/eIF5b, domain 3	Translation proteins	3	2
N-acetylmuramoyl-L-alanine amidase-like	N-acetylmuramoyl-L-alanine amidase-like	3	2
tRNA-binding arm	Class II aaRS and biotin synthetases	3	2
CAD & PB1 domains	PDZ domain-like	3	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	3	2
HLH, helix-loop-helix DNA-binding domain	Nuclear receptor coactivator interlocking domain	3	1
P-loop containing nucleoside triphosphate hydrolases	ArfGap/RecO-like zinc finger	3	2
Ran binding protein zinc finger-like	RING/U-box	3	3
Sec63 N-terminal domain-like	E set domains	3	3
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	3	3
Myosin S1 fragment, N-terminal domain	Myosin rod fragments	3	2
Nucleotide cyclase	P-loop containing nucleoside triphosphate hydrolases	3	1
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	3	2
UBC-like	Endosomal sorting complex assembly domain	3	1
p53 tetramerization domain	SAM/Pointed domain	3	1
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	3	3
E set domains	Anthrax protective antigen	3	3
FYVE/PHD zinc finger	HIT/MYND zinc finger-like	3	2
TGS-like	Class II aaRS ABD-related	3	2
SAND domain-like	HIT/MYND zinc finger-like	3	1
Sialidases	Sialidases	3	2
E set domains	DEATH domain	3	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	3	3
RING/U-box	NHL repeat	3	2
Ankyrin repeat	Cap-Gly domain	3	3
Ubiquitin-like	Ran binding protein zinc finger-like	3	2
DBL homology domain (DH-domain)	FYVE/PHD zinc finger	3	2
Ribosomal protein L25-like	Class II aaRS and biotin synthetases	3	1
Concanavalin A-like lectins/glucanases	Complement control module/SCR domain	3	3
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	3	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	3	2
(Trans)glycosidases	Trefoil	3	3
BRCT domain	post-AAA+ oligomerization domain-like	3	2
"Winged helix" DNA-binding domain	occludin/ELL-like	3	1
Ubiquitin-like	FYVE/PHD zinc finger	3	1
SH2 domain	PLC-like phosphodiesterases	3	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	3	2
FAD/NAD(P)-binding domain	Folate-binding domain	3	2
Fibronectin type III	YWTD domain	3	3
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	1
Cytidine deaminase-like	Cytidine deaminase-like	3	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex; beta-sheet shell regions	3	2
Second domain of FERM	DBL homology domain (DH-domain)	3	3
Kix domain of CBP (creb binding protein)	RING/U-box	3	1
Glucocorticoid receptor-like (DNA-binding domain)	Ribonuclease H-like	3	2
CAD & PB1 domains	UBA-like	3	2
beta-beta-alpha zinc fingers	FYVE/PHD zinc finger	3	1
BRK domain-like	BRK domain-like	3	1
L domain-like	C-terminal, gelsolin-like domain of Sec23/24	3	1
Nucleotidylyl transferase	Class II aaRS and biotin synthetases	3	1
BRCA2 helical domain	BRCA2 tower domain	3	1
WD40 repeat-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	3	2
F-box domain	Pectin lyase-like	3	2
Thioredoxin-like	Nucleoside diphosphate kinase, NDK	3	2
Arginase/deacetylase	Arginase/deacetylase	3	2
Surp module (SWAP domain)	Ubiquitin-like	3	1
Phosphofructokinase	Phosphofructokinase	3	1
G protein-binding domain	G protein-binding domain	3	1
Kix domain of CBP (creb binding protein)	Bromodomain	3	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	3	2
Spermadhesin, CUB domain	TIMP-like	3	3
Tudor/PWWP/MBT	HIV integrase-binding domain	3	1
PDZ domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	3	3
PUA domain-like	Nucleotidylyl transferase	3	1
Sema domain	Protein kinase-like (PK-like)	3	3
EGF/Laminin	Heme-dependent peroxidases	3	2
E set domains	Protein kinase-like (PK-like)	3	3
Tumor suppressor gene product Apc	ARM repeat	3	2
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	3	2
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	3	1
SH3-domain	CAD & PB1 domains	3	2
CAD & PB1 domains	RING/U-box	3	2
Phospholipase A2, PLA2	Phospholipase A2, PLA2	3	2
CBS-domain pair	cAMP-binding domain-like	3	2
Ribosomal protein L25-like	Class II aaRS ABD-related	3	1
Plexin repeat	Protein kinase-like (PK-like)	3	3
p53-like transcription factors	Ankyrin repeat	3	1
TAZ domain	Nuclear receptor coactivator interlocking domain	3	1
DNase I-like	GTPase activation domain, GAP	3	1
BRCA2 helical domain	Nucleic acid-binding proteins	3	1
Chaperone J-domain	Homeodomain-like	3	2
RuvA domain 2-like	RuvA domain 2-like	3	3
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	3	1
p53-like transcription factors	DEATH domain	3	1
PH domain-like	Tropomyosin	3	2
L domain-like	P-loop containing nucleoside triphosphate hydrolases	3	3
Concanavalin A-like lectins/glucanases	TSP-1 type 1 repeat	3	1
ARM repeat	"Winged helix" DNA-binding domain	3	1
WD40 repeat-like	SNARE fusion complex	3	1
RUN domain-like	PH domain-like	3	3
ARM repeat	POZ domain	3	2
SNARE-like	SNARE fusion complex	3	2
Ribosomal protein L25-like	S15/NS1 RNA-binding domain	3	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	3	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	2
Nucleic acid-binding proteins	EF-hand	3	2
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
GST C-terminal domain-like	Class II aaRS and biotin synthetases	3	1
Heme-dependent peroxidases	EF-hand	3	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	3	2
Ankyrin repeat	SET domain	3	1
UBC-like	RING/U-box	3	2
BPTI-like	Immunoglobulin	3	3
L domain-like	Actin depolymerizing proteins	3	1
DNA-binding domain	Bromodomain	3	3
MIT domain	P-loop containing nucleoside triphosphate hydrolases	3	1
Glycosyl hydrolase domain	Glycosyl hydrolase domain	3	3
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	3	1
Protein kinase-like (PK-like)	WD40 repeat-like	3	3
Ankyrin repeat	HIT/MYND zinc finger-like	3	2
UBA-like	Protein kinase-like (PK-like)	3	2
SH2 domain	DNase I-like	3	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	3	1
Cupredoxins	Galactose-binding domain-like	3	3
DEK C-terminal domain	(Phosphotyrosine protein) phosphatases II	3	1
Trypsin-like serine proteases	PDZ domain-like	3	2
SH2 domain	SAM/Pointed domain	3	2
Ribosomal protein L25-like	C-terminal domain of ProRS	3	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
TPR-like	HSP20-like chaperones	3	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	VPS9 domain	3	3
Kringle-like	Spermadhesin, CUB domain	3	1
Heme-dependent peroxidases	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	1
SH3-domain	PLC-like phosphodiesterases	3	2
FYVE/PHD zinc finger	SAP domain	3	1
Complement control module/SCR domain	Fibronectin type III	3	3
MFS general substrate transporter	Pentapeptide repeat-like	3	1
p53-like transcription factors	SAM/Pointed domain	3	1
Formyltransferase	ALDH-like	3	2
BRK domain-like	Bromodomain	3	1
SAP domain	P-loop containing nucleoside triphosphate hydrolases	3	2
ARID-like	ARM repeat	3	1
TRAF domain-like	POZ domain	3	1
Kazal-type serine protease inhibitors	Trypsin-like serine proteases	3	2
Fibrinogen coiled-coil and central regions	Fibrinogen C-terminal domain-like	3	3
FF domain	GTPase activation domain, GAP	3	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	3	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
MIT domain	Protein kinase-like (PK-like)	3	3
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	3	1
Tudor/PWWP/MBT	Galactose-binding domain-like	3	2
DNA-binding domain	FYVE/PHD zinc finger	3	3
Protein kinase-like (PK-like)	Tricorn protease domain 2	3	2
Nucleotidylyl transferase	C-terminal domain of ProRS	3	1
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	3	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	PKD domain	3	3
MgtE membrane domain-like	MgtE membrane domain-like	3	2
Chaperone J-domain	Thioredoxin-like	3	2
Bromodomain	Nuclear receptor coactivator interlocking domain	3	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
ENTH/VHS domain	I/LWEQ domain	3	2
BAR/IMD domain-like	SH2 domain	3	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	3	2
TAZ domain	Kix domain of CBP (creb binding protein)	3	1
Somatomedin B domain	Hemopexin-like domain	3	2
Homeodomain-like	RING/U-box	3	2
WD40 repeat-like	FYVE/PHD zinc finger	3	3
CCCH zinc finger	beta-beta-alpha zinc fingers	3	3
GST C-terminal domain-like	C-terminal domain of ProRS	3	1
SAM/Pointed domain	RING/U-box	3	3
FAS1 domain	EGF/Laminin	3	3
Histone-fold	Macro domain-like	3	1
SH3-domain	Immunoglobulin	3	3
Hairpin loop containing domain-like	Trypsin-like serine proteases	3	3
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	1
Homeodomain-like	FAD-linked reductases, C-terminal domain	3	2
AN1-like Zinc finger	AN1-like Zinc finger	3	2
TSP-1 type 1 repeat	EGF/Laminin	3	1
PYP-like sensor domain (PAS domain)	Nuclear receptor coactivator interlocking domain	3	1
Nucleic acid-binding proteins	BRCA2 tower domain	3	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	3	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	2
FMT C-terminal domain-like	ALDH-like	3	2
Nucleotidylyl transferase	Class II aaRS ABD-related	3	1
Kelch motif	Fibronectin type III	3	1
HMA, heavy metal-associated domain	HAD-like	3	3
P-loop containing nucleoside triphosphate hydrolases	Prefoldin	3	2
RNA-binding domain, RBD	dsRNA-binding domain-like	3	2
DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	3	3
Galactose mutarotase-like	Galactose mutarotase-like	3	3
L domain-like	PDZ domain-like	3	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	2
Hairpin loop containing domain-like	Kringle-like	3	3
SAP domain	RING/U-box	3	1
Growth factor receptor domain	Spermadhesin, CUB domain	3	3
Calponin-homology domain, CH-domain	SH2 domain	3	1
FAD-linked reductases, C-terminal domain	Folate-binding domain	3	2
ARM repeat	Rap/Ran-GAP	3	1
Spectrin repeat	GAS2 domain-like	3	3
Tudor/PWWP/MBT	HIT/MYND zinc finger-like	3	2
Tudor/PWWP/MBT	ARID-like	3	2
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	3	1
cAMP-binding domain-like	FabD/lysophospholipase-like	3	1
FnI-like domain	TSP type-3 repeat	3	1
L domain-like	DNase I-like	3	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	3	2
TPR-like	PUA domain-like	3	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	3	2
PriA/YqbF domain	GINS helical bundle-like	3	2
POZ domain	Skp1 dimerisation domain-like	3	1
Glucocorticoid receptor-like (DNA-binding domain)	Protein kinase-like (PK-like)	3	2
beta-beta-alpha zinc fingers	Leucine zipper domain	3	1
DNA-binding protein LAG-1 (CSL)	E set domains	3	1
Tudor/PWWP/MBT	Chromo domain-like	3	2
PK beta-barrel domain-like	PK C-terminal domain-like	3	1
Protein kinase-like (PK-like)	L27 domain	3	1
SAP domain	Concanavalin A-like lectins/glucanases	3	2
Nucleic acid-binding proteins	BRCT domain	3	2
Histone-fold	ARM repeat	3	2
Bromodomain	HIT/MYND zinc finger-like	3	2
PX domain	Outer arm dynein light chain 1	3	2
RING/U-box	Trimerization domain of TRAF	3	2
Protein kinase-like (PK-like)	RCC1/BLIP-II	3	2
WWE domain	WWE domain	3	2
TAZ domain	Bromodomain	3	1
DUSP-like	Ubiquitin-like	3	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	3	2
EGF/Laminin	NHL repeat	3	3
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	3	1
UBC-like	UBA-like	2	1
L domain-like	PP2C-like	2	1
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	2	2
DBL homology domain (DH-domain)	VPS9 domain	2	2
GFP-like	YWTD domain	2	2
PX domain	MIT domain	2	2
Calponin-homology domain, CH-domain	Ubiquitin-like	2	1
vWA-like	SPOC domain-like	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
FnI-like domain	Kringle-like	2	2
NHL repeat	Soluble quinoprotein glucose dehydrogenase	2	1
Ubiquitin-like	Zn-binding ribosomal proteins	2	2
LDL receptor-like module	L domain-like	2	1
Growth factor receptor domain	PDZ domain-like	2	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	2
FnI-like domain	L domain-like	2	2
PRP4-like	Functional domain of the splicing factor Prp18	2	1
WD40 repeat-like	Cysteine proteinases	2	1
TPR-like	CAD & PB1 domains	2	1
Calponin-homology domain, CH-domain	RING/U-box	2	1
LDL receptor-like module	Protein kinase-like (PK-like)	2	2
RNA-binding domain, RBD	beta-beta-alpha zinc fingers	2	2
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	2	1
Tropomyosin	Smc hinge domain	2	2
SAM/Pointed domain	ArfGap/RecO-like zinc finger	2	1
ACT-like	ACT-like	2	1
vWA-like	BPTI-like	2	2
TPR-like	RNI-like	2	2
Elafin-like	Kazal-type serine protease inhibitors	2	2
L domain-like	Hormone receptor domain	2	1
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	2	2
Ankyrin repeat	RNI-like	2	2
GFP-like	Thyroglobulin type-1 domain	2	2
alpha/beta-Hydrolases	alpha/beta-Hydrolases	2	2
Nucleic acid-binding proteins	eIF2alpha middle domain-like	2	1
Ubiquitin-like	Ankyrin repeat	2	2
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	2	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Ubiquitin-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	1
P-loop containing nucleoside triphosphate hydrolases	Microbial and mitochondrial ADK, insert "zinc finger" domain	2	2
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	2	1
Apolipoprotein	Apolipoprotein A-I	2	1
Kazal-type serine protease inhibitors	PDZ domain-like	2	1
UBC-like	Class II aaRS and biotin synthetases	2	1
PH domain-like	Glycolipid transfer protein, GLTP	2	1
Multidrug efflux transporter AcrB transmembrane domain	NAD-binding domain of HMG-CoA reductase	2	1
CCCH zinc finger	Retrovirus zinc finger-like domains	2	2
Apolipoprotein	Apolipoprotein	2	1
Rabenosyn-5 Rab-binding domain-like	Rabenosyn-5 Rab-binding domain-like	2	1
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	2	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	2	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
N-terminal coiled coil domain from apc	Tumor suppressor gene product Apc	2	1
vWA-like	Trypsin-like serine proteases	2	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipase/lipooxygenase domain (PLAT/LH2 domain)	2	2
Mib/herc2 domain-like	Hect, E3 ligase catalytic domain	2	2
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	2	1
UBA-like	Hect, E3 ligase catalytic domain	2	1
Ribosomal protein S5 domain 2-like	HMG-box	2	1
UBA-like	WWE domain	2	1
UBA-like	Thioredoxin-like	2	1
PAZ domain	dsRNA-binding domain-like	2	1
RCC1/BLIP-II	RING/U-box	2	1
Immunoglobulin	Family A G protein-coupled receptor-like	2	2
F-box domain	ApaG-like	2	1
Ankyrin repeat	Nudix	2	2
TPR-like	CCCH zinc finger	2	2
KRAB domain (Kruppel-associated box)	KRAB domain (Kruppel-associated box)	2	2
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	2	2
LEM domain	RNA-binding domain, RBD	2	1
Spermadhesin, CUB domain	LCCL domain	2	2
Nucleic acid-binding proteins	SAP domain	2	1
E set domains	AMPKBI-like	2	1
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	2	1
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	2	1
PH domain-like	Bet v1-like	2	1
FAD-linked reductases, C-terminal domain	Aminomethyltransferase beta-barrel domain	2	1
Plakin repeat	EF-hand	2	2
L domain-like	WD40 repeat-like	2	2
EGF/Laminin	EF-hand	2	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	2	2
Oligoxyloglucan reducing end-specific cellobiohydrolase	YWTD domain	2	2
"Winged helix" DNA-binding domain	SAICAR synthase-like	2	1
PR-1-like	LCCL domain	2	1
Tudor/PWWP/MBT	HMG-box	2	2
Chaperone J-domain	ARM repeat	2	1
FYVE/PHD zinc finger	Rabenosyn-5 Rab-binding domain-like	2	1
beta-sandwich domain of Sec23/24	beta-sandwich domain of Sec23/24	2	2
CRAL/TRIO N-terminal domain	PapD-like	2	1
RNA-binding domain, RBD	Surp module (SWAP domain)	2	1
C-terminal, gelsolin-like domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	2	1
Glucocorticoid receptor-like (DNA-binding domain)	Nucleic acid-binding proteins	2	1
Calpain large subunit, middle domain (domain III)	C2 domain (Calcium/lipid-binding domain, CaLB)	2	1
PreATP-grasp domain	Methylglyoxal synthase-like	2	2
(Phosphotyrosine protein) phosphatases II	FYVE/PHD zinc finger	2	1
SH3-domain	S-adenosyl-L-methionine-dependent methyltransferases	2	2
Galactose-binding domain-like	Mib/herc2 domain-like	2	2
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	WD40 repeat-like	2	2
UBA-like	Phosphoglycerate mutase-like	2	1
PKD domain	Lipase/lipooxygenase domain (PLAT/LH2 domain)	2	2
Chromo domain-like	SET domain	2	1
Thyroglobulin type-1 domain	YWTD domain	2	2
Glucocorticoid receptor-like (DNA-binding domain)	ATP-dependent DNA ligase DNA-binding domain	2	1
SAM/Pointed domain	Toll/Interleukin receptor TIR domain	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	2	1
Acyl-CoA binding protein	ClpP/crotonase	2	2
Clathrin heavy-chain terminal domain	ARM repeat	2	1
WD40 repeat-like	Ribonuclease H-like	2	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	2	2
beta-lactamase/transpeptidase-like	Ankyrin repeat	2	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	2	1
Amine oxidase N-terminal region	Amine oxidase catalytic domain	2	2
TPR-like	PIN domain-like	2	1
Acyl-CoA binding protein	Supernatant protein factor (SPF), C-terminal domain	2	2
Plakin repeat	GAS2 domain-like	2	2
SPOC domain-like	SAP domain	2	2
Concanavalin A-like lectins/glucanases	SOCS box-like	2	1
CalX-like	Concanavalin A-like lectins/glucanases	2	2
Ankyrin repeat	Fibronectin type III	2	2
Histone-fold	PH domain-like	2	2
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Snake toxin-like	Snake toxin-like	2	2
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
TPR-like	Clavaminate synthase-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	1
Tropomyosin	FYVE/PHD zinc finger	2	1
Metalloproteases ("zincins"), catalytic domain	TRAF domain-like	2	2
Tudor/PWWP/MBT	ARM repeat	2	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	2	2
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
PDZ domain-like	Nitric oxide (NO) synthase oxygenase domain	2	2
GroEL apical domain-like	SAICAR synthase-like	2	1
S13-like H2TH domain	Glucocorticoid receptor-like (DNA-binding domain)	2	2
RING/U-box	BRCT domain	2	2
PDZ domain-like	Riboflavin synthase domain-like	2	2
Cap-Gly domain	Ubiquitin-like	2	2
Spermadhesin, CUB domain	Frizzled cysteine-rich domain	2	1
Ribonuclease H-like	Ribonuclease H-like	2	2
GroEL-intermediate domain like	SAICAR synthase-like	2	1
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	2	2
Eukaryotic type KH-domain (KH-domain type I)	Tudor/PWWP/MBT	2	2
RNA-binding domain, RBD	RING/U-box	2	2
Tudor/PWWP/MBT	CCHHC domain	2	2
Cysteine proteinases	HIT/MYND zinc finger-like	2	1
Ubiquitin-like	XPC-binding domain	2	2
Oligoxyloglucan reducing end-specific cellobiohydrolase	LDL receptor-like module	2	2
POZ domain	FYVE/PHD zinc finger	2	2
Class I glutamine amidotransferase-like	PreATP-grasp domain	2	2
PDZ domain-like	Ras GEF	2	2
FAS1 domain	C-type lectin-like	2	2
EGF/Laminin	Thyroglobulin type-1 domain	2	2
HSP20-like chaperones	Cysteine proteinases	2	1
Concanavalin A-like lectins/glucanases	Assembly domain of cartilage oligomeric matrix protein	2	2
P-loop containing nucleoside triphosphate hydrolases	SOCS box-like	2	1
Ubiquitin-like	Chaperone J-domain	2	1
ITPase-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
(Trans)glycosidases	Invertebrate chitin-binding proteins	2	1
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	2	1
Galactose-binding domain-like	Kelch motif	2	1
Ankyrin repeat	FYVE/PHD zinc finger	2	2
DBL homology domain (DH-domain)	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	2	2
Kringle-like	Protein kinase-like (PK-like)	2	2
LEM domain	LEM domain	2	1
Class II aaRS and biotin synthetases	Translation proteins	2	1
TSP-1 type 1 repeat	Complement control module/SCR domain	2	2
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	2	1
E set domains	Galactose-binding domain-like	2	1
Family A G protein-coupled receptor-like	Family A G protein-coupled receptor-like	2	2
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	2	1
EF-hand	Tropomyosin	2	1
L30e-like	alpha/beta knot	2	2
Histone-fold	DBL homology domain (DH-domain)	2	2
CRAL/TRIO domain	GTPase activation domain, GAP	2	2
(Trans)glycosidases	Six-hairpin glycosidases	2	1
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	2	2
Ubiquitin-like	TPR-like	2	1
PYP-like sensor domain (PAS domain)	HD-domain/PDEase-like	2	1
VPS9 domain	Ubiquitin-like	2	2
L domain-like	DEATH domain	2	1
Immunoglobulin	TIMP-like	2	2
SMAD/FHA domain	PDZ domain-like	2	2
Spectrin repeat	Immunoglobulin	2	2
UBA-like	CCCH zinc finger	2	1
HIT/MYND zinc finger-like	TPR-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Cysteine-rich domain	2	2
Tudor/PWWP/MBT	BRCT domain	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Nucleotidyltransferase substrate binding subunit/domain	2	1
"Winged helix" DNA-binding domain	dsRNA-binding domain-like	2	2
RuvA domain 2-like	Nucleic acid-binding proteins	2	2
RING/U-box	DUSP-like	2	1
SMAD/FHA domain	Cap-Gly domain	2	1
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	2	2
WD40 repeat-like	Ypt/Rab-GAP domain of gyp1p	2	1
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	2	2
PDZ domain-like	BAR/IMD domain-like	2	2
BAR/IMD domain-like	Protein kinase-like (PK-like)	2	1
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	2	2
Kelch motif	EGF/Laminin	2	2
CRAL/TRIO domain	Immunoglobulin	2	2
EF-hand	Rhomboid-like	2	2
Tudor/PWWP/MBT	Staphylococcal nuclease	2	2
Galactose-binding domain-like	BRCT domain	2	1
Thioredoxin-like	NHL repeat	2	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	2	1
RCC1/BLIP-II	E set domains	2	1
P-loop containing nucleoside triphosphate hydrolases	Fzo-like conserved region	2	2
Thioesterase/thiol ester dehydrase-isomerase	Bet v1-like	2	2
Assembly domain of cartilage oligomeric matrix protein	EGF/Laminin	2	2
Zn-dependent exopeptidases	Zn-dependent exopeptidases	2	1
Kelch motif	C-type lectin-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HMG-box	2	1
PDZ domain-like	Myosin rod fragments	2	1
MPN010-like	SAM/Pointed domain	2	1
Class II MHC-associated invariant chain ectoplasmic trimerization domain	Thyroglobulin type-1 domain	2	1
Cytochrome b5-like heme/steroid binding domain	HSP20-like chaperones	2	1
ADP-ribosylation	vWA-like	2	2
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	2
Spectrin repeat	Protein kinase-like (PK-like)	2	2
HSP20-like chaperones	HSP20-like chaperones	2	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	2	1
HSP20-like chaperones	HIT/MYND zinc finger-like	2	1
FAD/NAD(P)-binding domain	EF-hand	2	1
Soluble quinoprotein glucose dehydrogenase	WD40 repeat-like	2	2
TNF-like	TNF-like	2	1
WD40 repeat-like	UBC-like	2	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Fibronectin type III	2	2
Immunoglobulin	Kringle-like	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	1
RING/U-box	PDZ domain-like	2	1
BRCT domain	ADP-ribosylation	2	2
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	2	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	2	1
PH domain-like	PP2C-like	2	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Oligoxyloglucan reducing end-specific cellobiohydrolase	2	2
Inhibitor of apoptosis (IAP) repeat	DEATH domain	2	2
Amine oxidase N-terminal region	Amine oxidase N-terminal region	2	2
HSP20-like chaperones	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	1
DNA-binding domain	SET domain	2	1
TAF(II)230 TBP-binding fragment	Bromodomain	2	1
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	2	2
Nucleotidylyl transferase	Nucleotidylyl transferase	2	1
F-box domain	Concanavalin A-like lectins/glucanases	2	1
ACP-like	ALDH-like	2	1
Immunoglobulin	Hormone receptor domain	2	1
PX domain	Retrovirus zinc finger-like domains	2	2
UBA-like	XPC-binding domain	2	2
RNA-binding domain, RBD	Tricorn protease domain 2	2	1
GLA-domain	Growth factor receptor domain	2	1
FYVE/PHD zinc finger	F-box domain	2	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	2	1
LEM domain	Ankyrin repeat	2	2
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	2	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	2	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	2	2
Ypt/Rab-GAP domain of gyp1p	SH3-domain	2	1
F-box domain	SMI1/KNR4-like	2	1
Elafin-like	Immunoglobulin	2	2
PDZ domain-like	GTPase activation domain, GAP	2	2
PX domain	TPR-like	2	1
Immunoglobulin	3-carboxy-cis,cis-mucoante lactonizing enzyme	2	2
Quinoprotein alcohol dehydrogenase-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	2	2
PreATP-grasp domain	PreATP-grasp domain	2	2
Ankyrin repeat	Second domain of FERM	2	1
NHL repeat	WD40 repeat-like	2	2
SWIB/MDM2 domain	Ran binding protein zinc finger-like	2	2
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	2	2
Carboxypeptidase regulatory domain-like	Soluble quinoprotein glucose dehydrogenase	2	1
EGF/Laminin	Tropomyosin	2	2
Cysteine proteinases	Ribonuclease H-like	2	1
Chitinase insertion domain	Invertebrate chitin-binding proteins	2	1
ARM repeat	Zn-dependent exopeptidases	2	1
Domain of poly(ADP-ribose) polymerase	vWA-like	2	2
"Winged helix" DNA-binding domain	GroEL-intermediate domain like	2	1
TPR-like	UBA-like	2	1
Immunoglobulin	Caspase-like	2	1
HMG-box	Chromo domain-like	2	1
Cysteine proteinases	EPT/RTPC-like	2	2
SMI1/KNR4-like	ApaG-like	2	1
Assembly domain of cartilage oligomeric matrix protein	TSP type-3 repeat	2	2
Voltage-gated potassium channels	EF-hand	2	2
PDZ domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	2
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	2	1
Metalloproteases ("zincins"), catalytic domain	Fibronectin type III	2	2
HBS1-like domain	P-loop containing nucleoside triphosphate hydrolases	2	1
TPR-like	beta-beta-alpha zinc fingers	2	2
PHM/PNGase F	Calcium-dependent phosphotriesterase	2	2
PDZ domain-like	Flavoproteins	2	2
SEA domain	Spermadhesin, CUB domain	2	2
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	2	1
P-loop containing nucleoside triphosphate hydrolases	Cap-Gly domain	2	1
Myosin rod fragments	FYVE/PHD zinc finger	2	1
BRCT domain	PH domain-like	2	1
Ubiquitin-like	SMAD/FHA domain	2	2
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Methenyltetrahydrofolate cyclohydrolase-like	2	1
WD40 repeat-like	SOCS box-like	2	2
ITPase-like	"Winged helix" DNA-binding domain	2	1
Bcr-Abl oncoprotein oligomerization domain	PH domain-like	2	1
E set domains	Hect, E3 ligase catalytic domain	2	1
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	2	2
HMG-box	P-loop containing nucleoside triphosphate hydrolases	2	1
Ankyrin repeat	Hect, E3 ligase catalytic domain	2	2
Ubiquitin-like	SAM/Pointed domain	2	2
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	2	1
BRCT domain	DBL homology domain (DH-domain)	2	1
ARM repeat	GTPase activation domain, GAP	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	2	2
Regulator of G-protein signaling, RGS	Regulator of G-protein signaling, RGS	2	2
PH domain-like	HMG-box	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SET domain	2	1
BPTI-like	TIMP-like	2	2
Mannose 6-phosphate receptor domain	Kringle-like	2	1
N-terminal coiled coil domain from apc	ARM repeat	2	1
FYVE/PHD zinc finger	GroEL-intermediate domain like	2	1
Rhomboid-like	UBA-like	2	1
Ankyrin repeat	DBL homology domain (DH-domain)	2	1
EGF/Laminin	Kringle-like	2	2
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	2	1
TPR-like	Chaperone J-domain	2	1
LDL receptor-like module	Mannose 6-phosphate receptor domain	2	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	2	1
TPR-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	1
GLA-domain	Concanavalin A-like lectins/glucanases	2	1
Dcp2 domain-like	Nudix	2	1
FAD/NAD(P)-binding domain	Aminomethyltransferase beta-barrel domain	2	1
Vacuolar ATP synthase subunit C	Vacuolar ATP synthase subunit C	2	1
WW domain	RGC domain-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Chaperone J-domain	2	1
DNase I-like	SAM/Pointed domain	2	1
FYVE/PHD zinc finger	SAICAR synthase-like	2	1
FMT C-terminal domain-like	ACP-like	2	1
FYVE/PHD zinc finger	GroEL apical domain-like	2	1
Elafin-like	TIMP-like	2	2
Kringle-like	Hemopexin-like domain	2	1
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	2	1
CRAL/TRIO domain	Protein kinase-like (PK-like)	2	2
Formyltransferase	ACP-like	2	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	2
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	2	2
Integrin alpha N-terminal domain	Growth factor receptor domain	2	2
HIT-like	HIT-like	2	1
SEA domain	LDL receptor-like module	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	2
HBS1-like domain	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
PAZ domain	RNase III domain-like	2	1
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	2	1
Myosin rod fragments	Cysteine-rich domain	2	2
EF-hand	Galactose-binding domain-like	2	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	2	1
SH2 domain	UBA-like	2	2
RNA-binding domain, RBD	Cyclophilin-like	2	2
Ankyrin repeat	Eukaryotic type KH-domain (KH-domain type I)	2	2
UBC-like	Protein kinase-like (PK-like)	2	1
SEA domain	Concanavalin A-like lectins/glucanases	2	2
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	2	2
UBA-like	SH3-domain	2	1
HR1 repeat	PDZ domain-like	2	2
Bromodomain	HMG-box	2	2
MIT domain	F-box domain	2	1
Second domain of FERM	RING/U-box	2	1
Bromodomain	SET domain	2	1
Metalloproteases ("zincins"), catalytic domain	Kringle-like	2	1
CRAL/TRIO domain	PapD-like	2	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	2	2
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	2	2
Complement control module/SCR domain	vWA-like	2	1
Translational machinery components	L30e-like	2	2
Nucleic acid-binding proteins	TPR-like	2	2
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	2	2
PAH2 domain	Homeodomain-like	2	1
IP3 receptor type 1 binding core, domain 2	ARM repeat	2	2
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	2	2
"Winged helix" DNA-binding domain	GroEL apical domain-like	2	1
LCCL domain	LCCL domain	2	1
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	2	2
DUSP-like	DUSP-like	2	1
Fibronectin type III	BPTI-like	2	2
Chaperone J-domain	Nucleotidyltransferase substrate binding subunit/domain	2	1
Growth factor receptor domain	SEA domain	2	2
N-terminal domain of cbl (N-cbl)	UBA-like	2	2
Bcr-Abl oncoprotein oligomerization domain	GTPase activation domain, GAP	2	1
Chromo domain-like	ClpP/crotonase	2	1
Spermadhesin, CUB domain	Cystine-knot cytokines	2	1
Doublecortin (DC)	Protein kinase-like (PK-like)	2	2
PRTase-like	PRTase-like	2	2
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	2	1
DEATH domain	PDZ domain-like	2	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	2	2
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	2
Cysteine proteinases	C2 domain (Calcium/lipid-binding domain, CaLB)	2	1
Bcr-Abl oncoprotein oligomerization domain	DBL homology domain (DH-domain)	2	1
Kazal-type serine protease inhibitors	BPTI-like	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	2
USP8 N-terminal domain-like	JAB1/MPN domain	2	1
POZ domain	WD40 repeat-like	2	1
Growth factor receptor domain	Complement control module/SCR domain	2	2
PGBD-like	Kringle-like	2	1
Colipase-like	Colipase-like	2	1
Ankyrin repeat	Cysteine-rich domain	2	1
Galactose-binding domain-like	Galactose oxidase, central domain	2	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	2	1
FYVE/PHD zinc finger	PDZ domain-like	2	2
HBS1-like domain	Translation proteins	2	1
Ribonuclease H-like	HRDC-like	2	2
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	1
Ras GEF	PLC-like phosphodiesterases	2	2
MIT domain	MIT domain	2	2
Growth factor receptor domain	Trypsin-like serine proteases	2	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	2	1
PP2C-like	Protein serine/threonine phosphatase 2C, C-terminal domain	2	2
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	2
Myosin rod fragments	G protein-binding domain	2	2
EGF/Laminin	SEA domain	2	2
R3H domain	P-loop containing nucleoside triphosphate hydrolases	2	2
Cyclophilin-like	TPR-like	2	2
WD40 repeat-like	TPR-like	2	2
ARM repeat	EF-hand	2	2
TB module/8-cys domain	Kazal-type serine protease inhibitors	2	2
Ubiquitin-like	Acid proteases	2	1
Invasin/intimin cell-adhesion fragments	Invasin/intimin cell-adhesion fragments	2	1
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	2	2
PH domain-like	RING/U-box	2	1
LDL receptor-like module	Complement control module/SCR domain	2	2
LDL receptor-like module	Fibronectin type III	2	2
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	2	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	1
LCCL domain	vWA-like	2	2
DPP6 N-terminal domain-like	WD40 repeat-like	2	1
Multidrug efflux transporter AcrB transmembrane domain	Substrate-binding domain of HMG-CoA reductase	2	1
PR-1-like	Crisp domain-like	2	1
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
Ubiquitin-like	Nucleotidyltransferase substrate binding subunit/domain	2	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	2	2
Spermadhesin, CUB domain	Kelch motif	2	2
Kazal-type serine protease inhibitors	TIMP-like	2	2
FYVE/PHD zinc finger	Supernatant protein factor (SPF), C-terminal domain	2	2
EF-hand	UBA-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	2	1
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	2	2
Tudor/PWWP/MBT	Cullin homology domain	2	1
RNA-binding domain, RBD	SET domain	2	1
Galactose-binding domain-like	Cullin homology domain	2	1
CAD & PB1 domains	Cysteine-rich domain	2	1
cAMP-binding domain-like	PDZ domain-like	2	2
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Glucocorticoid receptor-like (DNA-binding domain)	DNA ligase/mRNA capping enzyme, catalytic domain	2	1
EGF/Laminin	Carboxypeptidase regulatory domain-like	2	2
PUA domain-like	SWIB/MDM2 domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Ribonuclease H-like	2	2
EGF/Laminin	Chicken cartilage matrix protein	2	2
RUN domain-like	RUN domain-like	2	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	2
GDNF receptor-like	GDNF receptor-like	2	2
C-type lectin-like	Growth factor receptor domain	2	2
Myosin rod fragments	PH domain-like	2	2
Histone-fold	Ras GEF	2	2
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	2	2
RNI-like	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain	2	1
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	2	2
RING/U-box	Protein kinase-like (PK-like)	2	1
Protein kinase-like (PK-like)	Myosin rod fragments	2	2
ARM repeat	Ankyrin repeat	2	2
Concanavalin A-like lectins/glucanases	TRAF domain-like	2	2
Elafin-like	Fibronectin type III	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	2	2
HSP20-like chaperones	Riboflavin synthase domain-like	2	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	2	1
Ankyrin repeat	Galactose-binding domain-like	2	2
Bcr-Abl oncoprotein oligomerization domain	C2 domain (Calcium/lipid-binding domain, CaLB)	2	1
Mib/herc2 domain-like	Mib/herc2 domain-like	2	1
LDL receptor-like module	Family A G protein-coupled receptor-like	2	1
Second domain of FERM	SH3-domain	2	2
Metalloproteases ("zincins"), catalytic domain	Complement control module/SCR domain	2	2
Complement control module/SCR domain	Periplasmic binding protein-like I	2	1
AXH domain	HMG-box	2	1
Nucleotide-binding domain	Nucleotide-binding domain	2	2
Second domain of FERM	Second domain of FERM	2	2
PH domain-like	L domain-like	2	1
ARM repeat	Cullin homology domain	2	1
SAP domain	EF-hand	2	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	2	1
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	2	2
Macro domain-like	WWE domain	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
PH domain-like	BSD domain-like	1	1
PH domain-like	VPS9 domain	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Cysteine proteinases	Tudor/PWWP/MBT	1	1
Trefoil	Trefoil	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
"Winged helix" DNA-binding domain	RING/U-box	1	1
ARM repeat	Homeodomain-like	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
ARM repeat	FYVE/PHD zinc finger	1	1
PX domain	GTPase activation domain, GAP	1	1
S-adenosyl-L-methionine-dependent methyltransferases	NAD(P)-binding Rossmann-fold domains	1	1
Macro domain-like	CRAL/TRIO domain	1	1
Macro domain-like	Macro domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	CCCH zinc finger	1	1
PDZ domain-like	PX domain	1	1
Tudor/PWWP/MBT	NAD(P)-binding Rossmann-fold domains	1	1
Granulin repeat	Granulin repeat	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
FMN-linked oxidoreductases	4Fe-4S ferredoxins	1	1
TROVE domain-like	vWA-like	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
Kelch motif	NHL repeat	1	1
Clavaminate synthase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	GroES-like	1	1
ARM repeat	Toll/Interleukin receptor TIR domain	1	1
Non-globular alpha+beta subunits of globular proteins	ISP domain	1	1
TRAF domain-like	WD40 repeat-like	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
Growth factor receptor domain	Family A G protein-coupled receptor-like	1	1
Seven-hairpin glycosidases	PA domain	1	1
Voltage-gated potassium channels	(Phosphotyrosine protein) phosphatases II	1	1
TrmE connector domain	P-loop containing nucleoside triphosphate hydrolases	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	RING/U-box	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Composite domain of metallo-dependent hydrolases	1	1
Ankyrin repeat	EF-hand	1	1
POZ domain	Galactose-binding domain-like	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
TPR-like	Protein kinase-like (PK-like)	1	1
Homocysteine S-methyltransferase	Dihydropteroate synthetase-like	1	1
Kazal-type serine protease inhibitors	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Elafin-like	Growth factor receptor domain	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
LDL receptor-like module	C-type lectin-like	1	1
DNA-binding domain	DNA-glycosylase	1	1
KRAB domain (Kruppel-associated box)	Homeodomain-like	1	1
Galactose oxidase, central domain	C-type lectin-like	1	1
WD40 repeat-like	Nucleoporin domain	1	1
FabD/lysophospholipase-like	alpha/beta-Hydrolases	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
L domain-like	Ubiquitin-like	1	1
beta-beta-alpha zinc fingers	WW domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	1	1
FYVE/PHD zinc finger	SMAD/FHA domain	1	1
Galactose oxidase, central domain	EGF/Laminin	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	Actin-like ATPase domain	1	1
(Trans)glycosidases	Acyl-CoA N-acyltransferases (Nat)	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	1	1
Methionine synthase domain	Cobalamin (vitamin B12)-binding domain	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	1	1
Heme-dependent peroxidases	Complement control module/SCR domain	1	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	1	1
BAG domain	BAG domain	1	1
(Trans)glycosidases	Fibronectin type III	1	1
Elafin-like	EGF/Laminin	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Concanavalin A-like lectins/glucanases	HCP-like	1	1
HAD-like	Acyl-CoA dehydrogenase NM domain-like	1	1
Cystine-knot cytokines	Heparin-binding domain from vascular endothelial growth factor	1	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	1	1
Microbial and mitochondrial ADK, insert "zinc finger" domain	Microbial and mitochondrial ADK, insert "zinc finger" domain	1	1
Metallo-dependent phosphatases	EF-hand	1	1
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
Cadherin-like	Dystroglycan, domain 2	1	1
GroES-like	alpha/beta-Hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	1	1
Band 7/SPFH domain	SCP-like	1	1
L domain-like	PKD domain	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Tryptophan synthase beta subunit-like PLP-dependent enzymes	1	1
Ankyrin repeat	FabD/lysophospholipase-like	1	1
Ribonuclease H-like	SH2 domain	1	1
Flavoproteins	Radical SAM enzymes	1	1
Protein kinase-like (PK-like)	RNA-binding domain, RBD	1	1
WD40 repeat-like	Peptidase/esterase 'gauge' domain	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
EF-hand	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
EGF/Laminin	Calcium-dependent phosphotriesterase	1	1
Ricin B-like lectins	Fibronectin type III	1	1
RCC1/BLIP-II	PH domain-like	1	1
Nucleotide-binding domain	4Fe-4S ferredoxins	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
Serine protease inhibitors	AbfB domain	1	1
F-box domain	PH domain-like	1	1
BRCT domain	vWA-like	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	1	1
Plexin repeat	CalX-like	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Chaperone J-domain	E set domains	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Chromo domain-like	Concanavalin A-like lectins/glucanases	1	1
BRCT domain	WGR domain-like	1	1
F-box domain	YccV-like	1	1
HR1 repeat	SH3-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	LigT-like	1	1
MHC antigen-recognition domain	MHC antigen-recognition domain	1	1
RING/U-box	beta-beta-alpha zinc fingers	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Thiolase-like	NAD(P)-binding Rossmann-fold domains	1	1
Concanavalin A-like lectins/glucanases	Trypsin-like serine proteases	1	1
GroES-like	ACP-like	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	Quinoprotein alcohol dehydrogenase-like	1	1
E set domains	Cupredoxins	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
PH domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
SIS domain	SIS domain	1	1
S-adenosyl-L-methionine-dependent methyltransferases	ACP-like	1	1
CAD & PB1 domains	His-Me finger endonucleases	1	1
SWIB/MDM2 domain	eIF1-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
Dihydropteroate synthetase-like	Cobalamin (vitamin B12)-binding domain	1	1
PYP-like sensor domain (PAS domain)	Positive stranded ssRNA viruses	1	1
EF-hand	DUSP-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Anticodon-binding domain of PheRS	1	1
Methylglyoxal synthase-like	Metallo-dependent hydrolases	1	1
PR-1-like	C-type lectin-like	1	1
Ubiquitin-like	HAD-like	1	1
PurM C-terminal domain-like	Formyltransferase	1	1
HAD-like	alpha/beta-Hydrolases	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
PKD domain	C-type lectin-like	1	1
Single hybrid motif	Single hybrid motif	1	1
WW domain	FKBP-like	1	1
S13-like H2TH domain	Ran binding protein zinc finger-like	1	1
B-box zinc-binding domain	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
FabD/lysophospholipase-like	ACP-like	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PUG domain-like	Ran binding protein zinc finger-like	1	1
F-box domain	Sec7 domain	1	1
PH domain-like	Cyclophilin-like	1	1
Retrovirus zinc finger-like domains	RING/U-box	1	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	1	1
Thiolase-like	FabD/lysophospholipase-like	1	1
Saposin	Metallo-dependent phosphatases	1	1
Somatomedin B domain	Complement control module/SCR domain	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Polo-box domain	1	1
TPR-like	Metallo-dependent phosphatases	1	1
ARM repeat	L domain-like	1	1
Fibrinogen C-terminal domain-like	Fibrinogen C-terminal domain-like	1	1
B-box zinc-binding domain	TRAF domain-like	1	1
Putative DNA-binding domain	Cation efflux protein transmembrane domain-like	1	1
TRAF domain-like	EGF/Laminin	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	NagB/RpiA/CoA transferase-like	1	1
Dihydropteroate synthetase-like	Methionine synthase activation domain-like	1	1
Aldolase	Single hybrid motif	1	1
R3H domain	RNA-binding domain, RBD	1	1
Thioredoxin-like	FAD-dependent thiol oxidase	1	1
Clavaminate synthase-like	Clavaminate synthase-like	1	1
Galactose oxidase, central domain	FYVE/PHD zinc finger	1	1
Rhodanese/Cell cycle control phosphatase	Cysteine proteinases	1	1
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Rudiment single hybrid motif	PurM C-terminal domain-like	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
Tropomyosin	Prefoldin	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-binding domain	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
Cap-Gly domain	Cysteine proteinases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Single hybrid motif	BRCT domain	1	1
Nitrous oxide reductase, N-terminal domain	Soluble quinoprotein glucose dehydrogenase	1	1
Lipocalins	BPTI-like	1	1
beta-beta-alpha zinc fingers	PAP/OAS1 substrate-binding domain	1	1
SAM/Pointed domain	Retrovirus zinc finger-like domains	1	1
Ubiquitin-like	EPT/RTPC-like	1	1
PDZ domain-like	Formin homology 2 domain (FH2 domain)	1	1
Thyroglobulin type-1 domain	alpha/beta-Hydrolases	1	1
ISP domain	Metallo-hydrolase/oxidoreductase	1	1
Anthrax protective antigen	Pectin lyase-like	1	1
CCHHC domain	SAM/Pointed domain	1	1
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	1	1
WD40 repeat-like	SAM/Pointed domain	1	1
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	1	1
YWTD domain	Protein kinase-like (PK-like)	1	1
PUG domain-like	RING/U-box	1	1
F-box domain	Cyclin-like	1	1
"Winged helix" DNA-binding domain	Class II aaRS and biotin synthetases	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
UBC-like	Ribosomal protein S5 domain 2-like	1	1
vWA-like	Cysteine-rich domain	1	1
SEA domain	Family A G protein-coupled receptor-like	1	1
Ankyrin repeat	Pseudo ankyrin repeat-like	1	1
Kazal-type serine protease inhibitors	Concanavalin A-like lectins/glucanases	1	1
ACP-like	alpha/beta-Hydrolases	1	1
Glutathione synthetase ATP-binding domain-like	Formyltransferase	1	1
Plexin repeat	Fibronectin type III	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Actin-like ATPase domain	AF1104-like	1	1
DAK1/DegV-like	DhaL-like	1	1
L domain-like	Calcium-dependent phosphotriesterase	1	1
SMAD/FHA domain	HAD-like	1	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	1	1
Methylglyoxal synthase-like	Composite domain of metallo-dependent hydrolases	1	1
Acetyl-CoA synthetase-like	ACP-like	1	1
YaeB-like	YaeB-like	1	1
UBA-like	DNase I-like	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Thioredoxin-like	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
EGF/Laminin	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
FMN-linked oxidoreductases	dsRNA-binding domain-like	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	1	1
Dipeptidyl peptidase I (cathepsin C), exclusion domain	Cysteine proteinases	1	1
Nucleotide-diphospho-sugar transferases	HAD-like	1	1
RCC1/BLIP-II	Cytochrome b5-like heme/steroid binding domain	1	1
Cobalamin (vitamin B12)-binding domain	Methionine synthase activation domain-like	1	1
EF-hand	FnI-like domain	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
DNA clamp	DNA clamp	1	1
Methionine synthase domain	Methionine synthase activation domain-like	1	1
Growth factor receptor domain	Intermediate filament protein, coiled coil region	1	1
L domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
Soluble quinoprotein glucose dehydrogenase	SRCR-like	1	1
HSP20-like chaperones	ThrRS/AlaRS common domain	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
vWA-like	SAP domain	1	1
Ribonuclease H-like	Zinc finger domain of DNA polymerase-alpha	1	1
RuvA domain 2-like	SH2 domain	1	1
Inhibitor of apoptosis (IAP) repeat	UBC-like	1	1
Ras GEF	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Carboxypeptidase regulatory domain-like	Immunoglobulin	1	1
Thiolase-like	ACP-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
Cadherin-like	Protein kinase-like (PK-like)	1	1
N-terminal domain of MutM-like DNA repair proteins	Ran binding protein zinc finger-like	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	1	1
Frizzled cysteine-rich domain	Concanavalin A-like lectins/glucanases	1	1
Histone-fold	Histone-fold	1	1
PAP/OAS1 substrate-binding domain	Ubiquitin-like	1	1
PKD domain	LDL receptor-like module	1	1
Ankyrin repeat	BRCT domain	1	1
Cytochrome b5-like heme/steroid binding domain	Mib/herc2 domain-like	1	1
Voltage-gated potassium channels	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Thiolase-like	GroES-like	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Rudiment single hybrid motif	PurM N-terminal domain-like	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
Homocysteine S-methyltransferase	Methionine synthase activation domain-like	1	1
RuvA domain 2-like	DNase I-like	1	1
Intermediate filament protein, coiled coil region	Myosin rod fragments	1	1
Growth factor receptor domain	Prefoldin	1	1
DEATH domain	HIN-2000 domain-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Kelch motif	1	1
POZ domain	Leucine zipper domain	1	1
PLP-dependent transferases	PK beta-barrel domain-like	1	1
Retrovirus zinc finger-like domains	P-loop containing nucleoside triphosphate hydrolases	1	1
Quinoprotein alcohol dehydrogenase-like	TolB, C-terminal domain	1	1
Concanavalin A-like lectins/glucanases	Hormone receptor domain	1	1
PH domain-like	RNI-like	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
HAD-like	Protein kinase-like (PK-like)	1	1
NHL repeat	Calcium-dependent phosphotriesterase	1	1
PurM N-terminal domain-like	Formyltransferase	1	1
SAP domain	Ribonuclease H-like	1	1
NAD(P)-binding Rossmann-fold domains	NagB/RpiA/CoA transferase-like	1	1
MFS general substrate transporter	alpha/beta knot	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	ACP-like	1	1
CCCH zinc finger	RNA-binding domain, RBD	1	1
RING/U-box	SH3-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	1	1
Ankyrin repeat	WD40 repeat-like	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Cadherin-like	Family A G protein-coupled receptor-like	1	1
Nucleotide-binding domain	FMN-linked oxidoreductases	1	1
NAD(P)-binding Rossmann-fold domains	alpha/beta-Hydrolases	1	1
Ankyrin repeat	Tropomyosin	1	1
vWA-like	C-terminal domain of Ku80	1	1
RING/U-box	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
CCHHC domain	Acyl-CoA N-acyltransferases (Nat)	1	1
PRP4-like	WD40 repeat-like	1	1
BRCT domain	DNA/RNA polymerases	1	1
RNA-binding domain, RBD	Nucleotidyltransferase	1	1
Formin homology 2 domain (FH2 domain)	Protein kinase-like (PK-like)	1	1
Mitotic arrest deficient-like 1, Mad1	Eferin C-derminal domain-like	1	1
SEA domain	Immunoglobulin	1	1
Telomeric repeat binding factor (TRF) dimerisation domain	Homeodomain-like	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
HAD-like	BRCT domain	1	1
SGNH hydrolase	SGNH hydrolase	1	1
Concanavalin A-like lectins/glucanases	FYVE/PHD zinc finger	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
RCC1/BLIP-II	Tudor/PWWP/MBT	1	1
P-loop containing nucleoside triphosphate hydrolases	beta-beta-alpha zinc fingers	1	1
Protein kinase-like (PK-like)	Chaperone J-domain	1	1
HAD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
FabD/lysophospholipase-like	NAD(P)-binding Rossmann-fold domains	1	1
FYVE/PHD zinc finger	Hect, E3 ligase catalytic domain	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
SAM/Pointed domain	HD-domain/PDEase-like	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
SET domain	WW domain	1	1
t-snare proteins	t-snare proteins	1	1
POZ domain	Pentapeptide repeat-like	1	1
BSD domain-like	BSD domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Ran binding protein zinc finger-like	1	1
Thiolase-like	SCP-like	1	1
NHL repeat	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Integrin beta tail domain	Fibronectin type III	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
TROVE domain-like	Soluble quinoprotein glucose dehydrogenase	1	1
EF-hand	WD40 repeat-like	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
Nucleotide-binding domain	FAD/NAD(P)-binding domain	1	1
WW domain	BAR/IMD domain-like	1	1
PX domain	CAD & PB1 domains	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
PreATP-grasp domain	Metallo-dependent hydrolases	1	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	1	1
EGF/Laminin	CalX-like	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
Zinc hairpin stack	RING/U-box	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	1	1
B-box zinc-binding domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
EF-hand	Ubiquitin-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
L domain-like	C-type lectin-like	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
TSP-1 type 1 repeat	Family A G protein-coupled receptor-like	1	1
E set domains	(Trans)glycosidases	1	1
Seven-hairpin glycosidases	Seven-hairpin glycosidases	1	1
vWA-like	Sensory domain-like	1	1
UBC-like	NAD(P)-binding Rossmann-fold domains	1	1
RNI-like	Ubiquitin-like	1	1
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	1	1
Immunoglobulin	SRCR-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	SH3-domain	1	1
Glutaminase/Asparaginase	Ankyrin repeat	1	1
Ankyrin repeat	L domain-like	1	1
POZ domain	A DNA-binding domain in eukaryotic transcription factors	1	1
Single hybrid motif	HAD-like	1	1
RCC1/BLIP-II	VPS9 domain	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
FnI-like domain	Trypsin-like serine proteases	1	1
VPS9 domain	Ankyrin repeat	1	1
Kazal-type serine protease inhibitors	SEA domain	1	1
alpha-helical ferredoxin	4Fe-4S ferredoxins	1	1
Rab geranylgeranyltransferase alpha-subunit, insert domain	Outer arm dynein light chain 1	1	1
alpha-helical ferredoxin	FMN-linked oxidoreductases	1	1
Periplasmic binding protein-like II	P-loop containing nucleoside triphosphate hydrolases	1	1
ISP transmembrane anchor	ISP domain	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Annexin	Annexin	1	1
Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	1	1
Protein prenylyltransferase	Rab geranylgeranyltransferase alpha-subunit, insert domain	1	1
KRAB domain (Kruppel-associated box)	Ribonuclease H-like	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
S-adenosyl-L-methionine-dependent methyltransferases	alpha/beta-Hydrolases	1	1
Chaperone J-domain	RNA-binding domain, RBD	1	1
RCC1/BLIP-II	Concanavalin A-like lectins/glucanases	1	1
Homocysteine S-methyltransferase	Methionine synthase domain	1	1
PH domain-like	Ran binding protein zinc finger-like	1	1
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	1	1
TPR-like	RNA-binding domain, RBD	1	1
TROVE domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
RmlC-like cupins	RmlC-like cupins	1	1
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	1	1
GST C-terminal domain-like	Methionyl-tRNA synthetase (MetRS), Zn-domain	1	1
beta-sandwich domain of Sec23/24	ARM repeat	1	1
Cupredoxins	Pectin lyase-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Metalloproteases ("zincins"), catalytic domain	1	1
Thioredoxin-like	FAD/NAD(P)-binding domain	1	1
Immunoglobulin	FnI-like domain	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
HSP20-like chaperones	Translation proteins	1	1
mRNA decapping enzyme DcpS N-terminal domain	HIT-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
UBA-like	Tudor/PWWP/MBT	1	1
PUG domain-like	Cysteine proteinases	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
Growth factor receptor domain	TSP type-3 repeat	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Composite domain of metallo-dependent hydrolases	1	1
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	1	1
Pseudouridine synthase	PUA domain-like	1	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	P-loop containing nucleoside triphosphate hydrolases	1	1
Soluble quinoprotein glucose dehydrogenase	Quinoprotein alcohol dehydrogenase-like	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
DNA/RNA polymerases	Zinc finger domain of DNA polymerase-alpha	1	1
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
RNA-binding domain, RBD	PAP/OAS1 substrate-binding domain	1	1
Frizzled cysteine-rich domain	SRCR-like	1	1
Thiolase-like	alpha/beta-Hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Restriction endonuclease-like	1	1
P-loop containing nucleoside triphosphate hydrolases	E set domains	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
WW domain	NAD(P)-binding Rossmann-fold domains	1	1
N-terminal domain of MutM-like DNA repair proteins	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
NagB/RpiA/CoA transferase-like	RNA-binding domain, RBD	1	1
Periplasmic binding protein-like I	Periplasmic binding protein-like I	1	1
USP8 N-terminal domain-like	Cysteine proteinases	1	1
Leech antihemostatic proteins	Leech antihemostatic proteins	1	1
Methylated DNA-protein cysteine methyltransferase domain	Methylated DNA-protein cysteine methyltransferase, C-terminal domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	beta-beta-alpha zinc fingers	1	1
Rudiment single hybrid motif	Formyltransferase	1	1
Tropomyosin	SAM/Pointed domain	1	1
Oxidoreductase molybdopterin-binding domain	E set domains	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
RCC1/BLIP-II	Mib/herc2 domain-like	1	1
LCCL domain	Galactose-binding domain-like	1	1
Kazal-type serine protease inhibitors	LDL receptor-like module	1	1
Concanavalin A-like lectins/glucanases	C-type lectin-like	1	1
PreATP-grasp domain	PurM C-terminal domain-like	1	1
vWA-like	FnI-like domain	1	1
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	1	1
Kringle-like	SRCR-like	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	1	1
Tudor/PWWP/MBT	Protein kinase-like (PK-like)	1	1
Actin depolymerizing proteins	SH3-domain	1	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	1	1
Cadherin-like	Hormone receptor domain	1	1
EGF/Laminin	TNF-like	1	1
WD40 repeat-like	Hect, E3 ligase catalytic domain	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	1	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	1	1
DEATH domain	WD40 repeat-like	1	1
Serine protease inhibitors	EGF/Laminin	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
Doublecortin (DC)	Pentapeptide repeat-like	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
Calcium-dependent phosphotriesterase	Quinoprotein alcohol dehydrogenase-like	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Carboxypeptidase regulatory domain-like	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
P-loop containing nucleoside triphosphate hydrolases	Soluble quinoprotein glucose dehydrogenase	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	alpha/beta-Hydrolases	1	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	1	1
Elafin-like	SEA domain	1	1
DBL homology domain (DH-domain)	Fibronectin type III	1	1
Rudiment single hybrid motif	Aldolase	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
DEATH domain	B-box zinc-binding domain	1	1
Molybdenum cofactor biosynthesis proteins	Adenine nucleotide alpha hydrolases-like	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Immunoglobulin	Heme-dependent peroxidases	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
RAP domain-like	RAP domain-like	1	1
F-box domain	L domain-like	1	1
Spermadhesin, CUB domain	Galactose oxidase, central domain	1	1
RCC1/BLIP-II	WD40 repeat-like	1	1
Thiolase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
dsRNA-binding domain-like	R3H domain	1	1
Ran binding protein zinc finger-like	Cysteine proteinases	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
Cytochrome b5-like heme/steroid binding domain	Hect, E3 ligase catalytic domain	1	1
PUA domain-like	eIF1-like	1	1
p53-like transcription factors	p53-like transcription factors	1	1
GTPase activation domain, GAP	GTPase activation domain, GAP	1	1
Eukaryotic type KH-domain (KH-domain type I)	SAM/Pointed domain	1	1
F-box domain	Kelch motif	1	1
Staphylococcal nuclease	Protein kinase-like (PK-like)	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
Ribokinase-like	Ribokinase-like	1	1
Cysteine-rich domain	(Phosphotyrosine protein) phosphatases II	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
TPR-like	PH domain-like	1	1
Mib/herc2 domain-like	Tudor/PWWP/MBT	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Ribonuclease H-like	"Winged helix" DNA-binding domain	1	1
PreATP-grasp domain	Composite domain of metallo-dependent hydrolases	1	1
Serine protease inhibitors	vWA-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Putative DNA-binding domain	1	1
vWA-like	CalX-like	1	1
L domain-like	RING/U-box	1	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	1	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
AF1104-like	AF1104-like	1	1
GLA-domain	Kringle-like	1	1
EF-hand	Myosin rod fragments	1	1
Ankyrin repeat	Oxysterol-binding protein-like	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	UBA-like	1	1
PreATP-grasp domain	Formyltransferase	1	1
Growth factor receptor domain	Hormone receptor domain	1	1
DEATH domain	Toll/Interleukin receptor TIR domain	1	1
Frizzled cysteine-rich domain	C-type lectin-like	1	1
RNI-like	Immunoglobulin	1	1
Protein kinase-like (PK-like)	Ypt/Rab-GAP domain of gyp1p	1	1
EF-hand	Immunoglobulin	1	1
TPR-like	Ran binding protein zinc finger-like	1	1
SEA domain	SRCR-like	1	1
RING/U-box	Formin homology 2 domain (FH2 domain)	1	1
EPT/RTPC-like	RNA 3'-terminal phosphate cyclase, RPTC, insert domain	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
RCC1/BLIP-II	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	1	1
Tudor/PWWP/MBT	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
Anthrax protective antigen	Cupredoxins	1	1
Protease propeptides/inhibitors	Growth factor receptor domain	1	1
dsRNA-binding domain-like	Protein kinase-like (PK-like)	1	1
Non-globular alpha+beta subunits of globular proteins	ISP transmembrane anchor	1	1
WW domain	dsRNA-binding domain-like	1	1
PLC-like phosphodiesterases	Ubiquitin-like	1	1
TRADD, N-terminal domain	DEATH domain	1	1
ARM repeat	beta-beta-alpha zinc fingers	1	1
Tricorn protease domain 2	TPR-like	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
Ubiquitin-like	BAG domain	1	1
NAD(P)-binding Rossmann-fold domains	Thioesterase/thiol ester dehydrase-isomerase	1	1
Kringle-like	HCP-like	1	1
SWIB/MDM2 domain	SWIB/MDM2 domain	1	1
Tex N-terminal region-like	SH2 domain	1	1
Starch-binding domain-like	Carboxypeptidase regulatory domain-like	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Rad50 coiled-coil Zn hook	1	1
P-loop containing nucleoside triphosphate hydrolases	AN1-like Zinc finger	1	1
ARM repeat	HMA, heavy metal-associated domain	1	1
Somatomedin B domain	EndoU-like	1	1
RING/U-box	NRDP1 C-terminal domain-like	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	1	1
Glutathione synthetase ATP-binding domain-like	Composite domain of metallo-dependent hydrolases	1	1
Prokaryotic type I DNA topoisomerase	Zinc beta-ribbon	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
FnI-like domain	Leech antihemostatic proteins	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
Apolipoprotein A-I	Apolipoprotein A-I	1	1
PUG domain-like	Galactose-binding domain-like	1	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	1	1
Cap-Gly domain	RNI-like	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
Kazal-type serine protease inhibitors	FnI-like domain	1	1
RUN domain-like	Supernatant protein factor (SPF), C-terminal domain	1	1
R3H domain	Ribonuclease H-like	1	1
SEA domain	Fibronectin type III	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
Ankyrin repeat	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
CHY zinc finger-like	RING/U-box	1	1
ISP domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
GST C-terminal domain-like	ValRS/IleRS/LeuRS editing domain	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
GST C-terminal domain-like	eEF-1beta-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	1	1
Homeodomain-like	JAB1/MPN domain	1	1
EGF/Laminin	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Ran binding protein zinc finger-like	Cyclophilin-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
Tricorn protease domain 2	ARM repeat	1	1
WD40 repeat-like	HMG-box	1	1
PDZ domain-like	EF-hand	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
Pentapeptide repeat-like	RNA-binding domain, RBD	1	1
Cytochrome b5-like heme/steroid binding domain	E set domains	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	CBS-domain pair	1	1
ISP domain	FAD/NAD(P)-binding domain	1	1
PreATP-grasp domain	PurM N-terminal domain-like	1	1
Nucleotidyltransferase	Ubiquitin-like	1	1
TROVE domain-like	WD40 repeat-like	1	1
C-type lectin-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
Terpenoid synthases	SH3-domain	1	1
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	1	1
Nitrous oxide reductase, N-terminal domain	Galactose oxidase, central domain	1	1
TRAF domain-like	NRDP1 C-terminal domain-like	1	1
Galactose oxidase, central domain	Galactose oxidase, central domain	1	1
Homocysteine S-methyltransferase	Cobalamin (vitamin B12)-binding domain	1	1
Cysteine proteinases	Galactose-binding domain-like	1	1
L domain-like	Putative isomerase YbhE	1	1
L domain-like	SAM/Pointed domain	1	1
PLP-dependent transferases	PLP-dependent transferases	1	1
Transmembrane di-heme cytochromes	a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
PX domain	SAM/Pointed domain	1	1
Heme-dependent peroxidases	FnI-like domain	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
alpha-helical ferredoxin	Nucleotide-binding domain	1	1
RING/U-box	Prefoldin	1	1
HAD-like	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
Rap30/74 interaction domains	Rap30/74 interaction domains	1	1
Nucleotidylyl transferase	SH2 domain	1	1
Spermadhesin, CUB domain	Family A G protein-coupled receptor-like	1	1
Sec63 N-terminal domain-like	Ribonuclease H-like	1	1
Doublecortin (DC)	POZ domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Chaperone J-domain	1	1
LDL receptor-like module	Immunoglobulin	1	1
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
R3H domain	AN1-like Zinc finger	1	1
FabD/lysophospholipase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Glycosyl hydrolase domain	Fibronectin type III	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
ARM repeat	alpha/beta knot	1	1
Arp2/3 complex subunits	Arp2/3 complex subunits	1	1
CalX-like	Fibronectin type III	1	1
Tudor/PWWP/MBT	Hect, E3 ligase catalytic domain	1	1
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
L domain-like	Heme-dependent peroxidases	1	1
FnI-like domain	Fibronectin type III	1	1
PDZ domain-like	Cysteine-rich domain	1	1
CalX-like	C-type lectin-like	1	1
Homeodomain-like	Formin homology 2 domain (FH2 domain)	1	1
Protein kinase-like (PK-like)	HCP-like	1	1
L domain-like	Polo-box domain	1	1
Cytochrome b5-like heme/steroid binding domain	Oxidoreductase molybdopterin-binding domain	1	1
Protein prenylyltransferase	Outer arm dynein light chain 1	1	1
ARM repeat	SAM/Pointed domain	1	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
S-adenosyl-L-methionine-dependent methyltransferases	GroES-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	CCCH zinc finger	1	1
YccV-like	ApaG-like	1	1
E set domains	Glycosyl hydrolase domain	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
Galactose-binding domain-like	TIMP-like	1	1
Arginase/deacetylase	RING/U-box	1	1
PurS-like	PurM C-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	1	1
FabD/lysophospholipase-like	GroES-like	1	1
beta-beta-alpha zinc fingers	Nucleotidyltransferase	1	1
SWIB/MDM2 domain	RING/U-box	1	1
Dihydropteroate synthetase-like	Methionine synthase domain	1	1
R3H domain	Ankyrin repeat	1	1
HIT/MYND zinc finger-like	SET domain	1	1
CAD & PB1 domains	C-terminal domain of DFF45/ICAD (DFF-C domain)	1	1
PABC (PABP) domain	Hect, E3 ligase catalytic domain	1	1
Aldolase	AFP III-like domain	1	1
Cytochrome b5-like heme/steroid binding domain	Tudor/PWWP/MBT	1	1
SAICAR synthase-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Formate/glycerate dehydrogenase catalytic domain-like	DHS-like NAD/FAD-binding domain	1	1
BEACH domain	FYVE/PHD zinc finger	1	1
Thioredoxin-like	ERP29 C domain-like	1	1
SMAD/FHA domain	RING/U-box	1	1
P-loop containing nucleoside triphosphate hydrolases	RGC domain-like	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
DUSP-like	EPT/RTPC-like	1	1
EGF/Laminin	Family A G protein-coupled receptor-like	1	1
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	1	1
ARM repeat	Mib/herc2 domain-like	1	1
THUMP domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
BAR/IMD domain-like	HR1 repeat	1	1
TSP-1 type 1 repeat	BPTI-like	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
SAM/Pointed domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
SMAD/FHA domain	Protein kinase-like (PK-like)	1	1
SMAD/FHA domain	HIT-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
TPR-like	Fic-like	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
RING/U-box	Cyclophilin-like	1	1
GTPase activation domain, GAP	VPS9 domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Tricorn protease domain 2	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	1	1
USP8 N-terminal domain-like	Rhodanese/Cell cycle control phosphatase	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	1	1
F-box domain	DBL homology domain (DH-domain)	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	NAD(P)-binding Rossmann-fold domains	1	1
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	1	1
Frizzled cysteine-rich domain	Trypsin-like serine proteases	1	1
Kazal-type serine protease inhibitors	SRCR-like	1	1
NAD(P)-binding Rossmann-fold domains	ACP-like	1	1
Ubiquitin-like	NAD kinase/diacylglycerol kinase-like	1	1
BPTI-like	LDL receptor-like module	1	1
Concanavalin A-like lectins/glucanases	Hect, E3 ligase catalytic domain	1	1
Thiolase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Hemopexin-like domain	Hemopexin-like domain	1	1
Starch-binding domain-like	(Phosphotyrosine protein) phosphatases II	1	1
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	1	1
Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	1	1
Starch-binding domain-like	PLC-like phosphodiesterases	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
FYVE/PHD zinc finger	EF-hand	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
UBC-like	LDH C-terminal domain-like	1	1
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	1	1
Cytochrome b5-like heme/steroid binding domain	Galactose-binding domain-like	1	1
PreATP-grasp domain	Aldolase	1	1
Somatomedin B domain	TSP-1 type 1 repeat	1	1
WD40 repeat-like	Tubby C-terminal domain-like	1	1
PurS-like	PurM N-terminal domain-like	1	1
HLH, helix-loop-helix DNA-binding domain	Positive stranded ssRNA viruses	1	1
ACP-like	Quinoprotein alcohol dehydrogenase-like	1	1
PH domain-like	Fibronectin type III	1	1
Pre-PUA domain	PUA domain-like	1	1
Concanavalin A-like lectins/glucanases	Serine protease inhibitors	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Lipocalins	1	1
RCC1/BLIP-II	DBL homology domain (DH-domain)	1	1
TRAF domain-like	Cysteine proteinases	1	1
MIT domain	Cysteine proteinases	1	1
DNA-glycosylase	Nudix	1	1
"Winged helix" DNA-binding domain	E set domains	1	1
Class I glutamine amidotransferase-like	Composite domain of metallo-dependent hydrolases	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Aldolase	1	1
PUG domain-like	Ubiquitin-like	1	1
L domain-like	Tropomyosin	1	1
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
Composite domain of metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
vWA-like	Immunoglobulin	1	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
E set domains	Pectin lyase-like	1	1
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	1	1
Terpenoid synthases	RUN domain-like	1	1
NAD(P)-binding Rossmann-fold domains	SCP-like	1	1
NAD(P)-binding Rossmann-fold domains	DHS-like NAD/FAD-binding domain	1	1
Carbamate kinase-like	ALDH-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
NHL repeat	Peptidase/esterase 'gauge' domain	1	1
Concanavalin A-like lectins/glucanases	SRCR-like	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Kringle-like	Fibronectin type III	1	1
CHY zinc finger-like	Zinc hairpin stack	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
Integrin beta tail domain	CalX-like	1	1